检索结果-南通市图书馆

Journal of Materials Science & Technology 2021年第26期85卷 184-193页

作者： Achmad Yanuar Maulana Jungwook Song Da Won leeg chae eun leeg Jongsik Kimg Department of Chemistry Dong-A UniversityBusan 49315South Korea Department of Chemical Engineering(BK21 FOUR Graduate Program) Dong-A UniversityBusan 49315South Korea

Sodium-ion batteries(SIBs)are considered one of the most promising energy storage systems for replacing lithium-ion batteries because of the high abundance and low cost of *** oxyfluoride(FeOF)is a promising conversion-based cathode material for SIBs because of its high theoretical capacity of about855 mA h g^(-1),low-cost chemical compositions,and its lower sensitivity to the size of charged carrier ***,the poor electrical conductivity and ionic diffusion of FeOF result in a low rate capability and *** this work,FeOF nanoparticles wrapped by graphitic carbon layers were synthesized using abietic or maleopimaric acid as both the carbon source and organic *** addition,the morphology of the FeOF particles was gradually controlled from rod to spherical shapes,simply depending on the rosin *** FeOF nanoparticles prepared with maleopimaric acid showed a large reversible discharge capacity of 356.7 mA h g^(-1)with a fading rate of 0.21%per cycle after 100 cycles at a current density of 100 mA g^(-1)and an excellent rate capability.

关键词： Na-ion batteries Cathode Iron oxyfluoride Graphitized carbon Maleopimaric acid

Protein Arginine Methyltransferase 1 Ablation in Motor Neurons Causes Mitochondrial Dysfunction Leading to Age-related Motor Neuron Degeneration with Muscle Loss

在线全文

学校读者我要写书评

暂无评论

Research 2024年第1期2023卷 637-649页

作者： Hyun-Kyung So Hyebeen Kim Jinwoo Lee Chang-Lim You chae-eun Yun Hyeon-Ju Jeong eun-Ju Jin Yunju Jo Dongryeol Ryu Gyu-Un Bae Jong-Sun Kang Department of Molecular Cell Biology Sungkyunkwan University School of MedicineSuwonKorea Single Cell Network Research Center Sungkyunkwan University School of MedicineSuwonKorea Research Institute of Aging-Related Diseases AniMusCureInc.SuwonKorea Drug Information Research Institute Muscle Physiome Research CenterCollege of PharmacySookmyung Women’s UniversitySeoulKorea

Neuromuscular dysfunction is tightly associated with muscle wasting that occurs with age or due to degenerative ***,the molecular mechanisms underlying neuromuscular dysfunction are currently *** studies have proposed important roles of Protein arginine methyltransferase 1(Prmt1)in muscle stem cell function and muscle *** the current study,we set out to determine the role of Prmt1 in neuromuscular function by generating mice with motor neuron-specific ablation of Prmt1(mnKO)using *** exhibited age-related motor neuron degeneration and neuromuscular dysfunction leading to premature muscle loss and ***1 deficiency also impaired motor function recovery and muscle reinnervation after sciatic nerve *** transcriptome analysis of aged mnKO lumbar spinal cords revealed alterations in genes related to inflammation,cell death,oxidative stress,and ***,mnKO lumbar spinal cords of sciatic nerve injury model or aged mice exhibited elevated cellular stress response in motor ***,Prmt1 inhibition in motor neurons elicited mitochondrial *** findings demonstrate that Prmt1 ablation in motor neurons causes agerelated motor neuron degeneration attributing to muscle ***,Prmt1 is a potential target for the prevention or intervention of sarcopenia and neuromuscular dysfunction related to aging.

关键词： degeneration impaired prevention

Real-time and label-free biosensing using moiré pattern generated by bioresponsive hydrogel

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

生物活性材料(英文) 2023年第5期23卷 383-393页

作者： Semin Kim Geehong Kim Yong Woo Ji chae-eun Moon Yuna Jung Hyung Keun Lee JaeJong Lee Won-Gun Koh Department of Chemical and Biomolecular Engineering Yonsei University50 Yonsei-roSeodaemun-guSeoul120-749Republic of Korea Korea Institute of Machinery&Materials Nano-Convergence Mechanical Systems Research Division156 Gajeongbuk-roYuseong-guDaejeon34103Republic of Korea Department of Ophthalmology Yongin Severance HospitalYonsei University College of Medicine363Dongbaekjukjeon-daeroGiheung-guYongin-siGyeonggi-do16995Republic of Korea Institute of Vision Research Department of OphthalmologyYonsei University College of Medicine50-1 Yonsei-roSeodaemun-guSeoul120-749Republic of Korea Department of Ophthalmology Graduate School of Medical ScienceBrain Korea 21 ProjectYonsei University College of MedicineRepublic of Korea College of Pharmacy Yonsei University85 Songdo Hwawak-roYeonsu-guIncheon26426Republic of Korea Department of Ophthalmology Gangnam Severance HospitalYonsei University College of Medicine211 Eonju-roGangnam-guSeoul06273Republic of Korea Department of Nanomechatronics University of Science and Technology217Gajeong-roYuseong-guDaejeon 34113Republic of Korea

Bioresponsive hydrogels are smart materials that respond to various external stimuli and exhibit great potential as biosensors owing to their capability of real-time and label-free ***,we propose a sensing platform based on bioresponsive hydrogels,employing the concept of moiré *** sets of line patterns with different pitch sizes are prepared;a hydrogel grating whose pitch size changes according to external stimuli and a reference grating with constant pitch *** volume changes of the hydrogel caused by external stimuli changes the pitch size of the hydrogel grating,and subsequently,the pitch sizes of the moiré patterns(moiré signal),whose values can be obtained in a real-time and label-free manner through customized moiré microscopy and signal *** confirming that the pH-induced swelling of hydrogel could be monitored using moiré patterns,we performed moiré pattern-based detection of specific proteins using protein-responsive hydrogel that underwent shrinking via interaction with target ***-derived neurotrophic factor and platelet-derived growth factor were selected as the model proteins,and our proposed system successfully detected both proteins at nanomolar *** both cases,the pitch size change of hydrogel grating was monitored much more sensitively using moiré patterns than through direct *** changes in the moiré signals caused by target proteins were detected in ex-vivo environments using a custom-made intraocular lens incorporating the hydrogel grating,demonstrating the capability of the proposed system to detect various markers in intraocular aqueous humor,when implanted in the eye.

关键词： Bioresponsive hydrogel Moirépattern Biosensing Intraocular lens Aqueous humor

Highly impermeable and flexible silica encapsulation films synthesized by sol-gel process

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2022年第8期15卷 7476-7483页

作者： Si-Hoon Kim Gyeong-Seok Hwang Donghwan Koo Dong-Hyun Seo Ye-Pil Kwon Hansuek Lee Hyesung Park eun-chae Jeon Ju-Young Kim School of Materials Science and Engineering University of UlsanTechno saneop-ro 55beon-gil 12Ulsan 44776Republic of Korea Department of Materials Science and Engineering Ulsan National Institute of Science and Technology(UNIST)UNIST-gil 50Ulsan 44919Republic of Korea Department of Physics Korea Advanced Institute of Science and Technology(KAIST)Daehak-ro 291Deajeon 34141Republic of Korea Graduate School of Semiconductor Materials and Devices Ulsan National Institute of Science and Technology(UNIST)UNIST-gil 50Ulsan 44919Republic of Korea

Silica thin films synthesized sol–gel process are proposed as flexible encapsulation materials.A sol–gel process provides a dense and stable amorphous silica structure,yielding an extremely high elastic deformation limit of 4.9%and extremely low water vapor transmission rate(WVTR)of 2.90×10^(−4)g/(m^(2)∙day)at 60℃and relative humidity of 85%.The WVTR is not degraded by cyclic bending deformations for the bending radius corresponding to a tensile strain of 3.3%in the silica encapsulation film,implying that the silica thin film is robust against the formation of pinhole-type defects by cyclic bending *** organic solar cells encapsulated with the silica films operate without degradation in power conversion efficiency for 50,000 bending cycles for a bending radius of 6 mm.

关键词： silica thin film sol-gel flexible encapsulation mechanical reliability flexible organic solar cell

Hybrid algorithm for modeling of fluid-structure interaction in incompressible, viscous flows

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 2012年第4期28卷 1030-1041页

作者： eun Jung chae Deniz Tolga Akcabay Department of Naval Architecture and Marine Engineering University of Michigan

The objective of this paper is to present and to validate a new hybrid coupling （HC） algorithm for modeling of fluid-structure interaction （FSI） in incompressible, viscous flows. The HC algorithm is able to avoid numerical instability issues associated with artificial added mass effects, which are often encountered by standard loosely coupled （LC） and tightly coupled （TC） algorithms, when modeling the FSI response of flexible structures in incompressible flow. The artificial added mass effect is caused by the lag in exchange of interfacial displacements and forces between the fluid and solid solvers in partitioned algorithms. The artificial added mass effect is much more prominent for light/flexible struc- tures moving in water, because the fluid forces are in the same order of magnitude as the solid forces, and because the speed at which numerical errors propagate in an incom- pressible fluid. The new HC algorithm avoids numerical instability issues associated with artificial added mass effects by embedding Theodorsen＇s analytical approximation of the hydroelastic forces in the solution process to obtain better initial estimates of the displacements. Details of the new HC algorithm are presented. Numerical validation studies are shown for the forced pitching response of a steel and a plastic hydrofoil. The results show that the HC algorithm is able to converge faster, and is able to avoid numerical insta- bility issues, compared to standard LC and TC algorithms, when modeling the transient FSI response of a plastic hydrofoil. Although the HC algorithm is only demonstrated for a NACA0009 hydrofoil subject to pure pitching motion, the method can be easily extended to model general 3-D FSI response and stability of complex, flexible structures in turbulent, incompressible, multiphase flows.

关键词： Fluid-structure interaction Viscous Incom- pressible Computational Added Mass Stability

A Proximal Promoter Region of Arabidopsis DREB2C Confers Tissue-specific Expression under Heat Stress

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2012年第9期54卷 640-651页

作者： Jihyun Je Chieun Song Jung eun Hwang chae Oh Lim Systems and Synthetic Agrobiotech Center and PMBBRC Division of Applied Life Science Gyeongsang National University

The dehydration-responsive element-binding factor 2C （DREB2C） is a member of the CBF/DREB subfamily of proteins, which contains a single APETALA2/Ethylene responsive element-binding factor （AP2/ERF） domain. To identify the expression pattern of the DREB2C gene, which contains multiple transcription cis-regulatory elements in its promoter, an approximately 1.4 kb upstream DREB2C sequence was fused to the β-glucuronidase reporter gene （GUS） and the recombinant p1244 construct was transformed into Arabidopsis thaliana （L.） Heynh. The promoter of the gene directed prominent GUS activity in the vasculature in diverse young dividing tissues. Upon applying heat stress （HS）, GUS staining was also enhanced in the vasculature of the growing tissues. Analysis of a series of 5＇-deletions of the DREB2C promoter revealed that a proximal upstream sequence sufficient for the tissue-specific spatial and temporal induction of GUS expression by HS is localized in the promoter region between -204 and -34 bps relative to the transcriptional start site. Furthermore, electrophoretic mobility shift assay （EMSA） demonstrated that nuclear protein binding activities specific to a -120 to -32 bp promoter fragment increased after HS. These results indicate that the TATA-proximal region and some latent trans-acting factors may cooperate in HS-induced activation of the Arabidopsis DREB2C promoter.

关键词： cis-acting elements β-glucuronidase gene expression histochemical assay promoter deletion transgenic plant.

pH-induced structural changes of surface immobilized poly (L-lysine) by two-dimensional (2D) infrared correlation study

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2015年第2期26卷 173-176页

作者： eun Joo Yoo Boknam chae Young Mee Jung Seung Woo Lee School of Chemical Engineering Yeungnam University Pohang Accelerator Laboratory Department of Chemistry Kangwon National University

This paper reports the pH-induced structural changes in the surface immobilized poly（L-lysine）（PLL）***-dimensional（2D） correlation analysis was applied to the Fourier transform infrared（FTIR）spectra of the surface-immobilized PLL film to examine the spectral changes induced by the alternations of the protonation state of the amino group in the side *** spectral changes in the FTIR spectra of the PLL film were observed between pH 7 and *** decrease in the protonation state of the amino group in the side chain induced spectral changes in the amino group as well as conformational changes in the alky]group in the side *** pH 1-8,the spectral changes in the amino and alkyl groups in the side chain occurred before those of the amide group in the main chain of the surface immobilized PLL film.

关键词： Poly(L-lysine)(PLL) Surface-immobilized polypeptide FT-IR spectroscopy 2D correlation spectroscopy

Sarcopenia is associated with Framingham risk score in the Korean population： Korean National Health and Nutrition Examination Survey （KNHANES） 2010-2011

在线全文

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2015年第4期12卷 366-372页

作者： chae-Hwa Byeon Kee-Young Kang Se-Hun Kang eun-Jin Bae Department of Family Medicine DaeDong Hospital Myeongnyun-dong Dongnae-gu Busan South Korea

BACKGROUND:Sarcopenia is a risk factor for metabolic disorders and cardiovascular disease, but the association between sarcopenia and cardiovascular risk factors according to age and obesity status in the general population remains unknown. We thus investigated these associations in the Korean population.;METHODS:We included 8,958 and 8,518 subjects from the fifth Korean National Health and Nutrition Examination Survey (KNHANES) (from 2010 and 2011, respectively). The study was restricted to participants ≥ 20 years old who had completed the health examination survey, including whole body dual-energy X-ray absorptiometry scans. After exclusion, 7,366 subjects (3,188 men, 4,178 women) were included in our final analysis. Age was categorized according to three age groups (20-39, 40-59, and ≥ 60 years), and subjects were categorized according to their sarcopenic and obesity status. Cardiovascular risk was assessed with Framingham risk score (FRS).;RESULTS:The sarcopenic obese group had a higher FRS than the non-sarcopenic obese group, which had a higher FRS than the non-sarcopenic non-obese group. Age-wise, the 20-39 year-old group showed a non-significant association between sarcopenia and FRS. In the 40-59 year-old group, regardless of obesity status, sarcopenic subjects had a higher FRS than non-sarcopenic subjects. In the ≥ 60 year-old group, sarcopenic subjects had a higher FRS than non-sarcopenic subjects for the non-obese group.;CONCLUSIONS:Sarcopenia was associated with cardiovascular disease and may be an early predictor of its susceptibility in both elderly and middle-aged subjects. Thus, management of sarcopenia is necessary to prevent cardiovascular disease.

关键词：健康调查风险评估营养调查韩国肌肉人口心血管疾病分相

Regulation of c-SMAC formation and AKT-mTOR signaling by the TSG101-IFT20 axis in CD4^(+)T cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2023年第5期20卷 525-539页

作者： Jiung Jeong In Kang Yumin Kim Keun Bon Ku Jang Hyun Park Hyun-Jin Kim chae Won Kim Jeongwoo La Hi eun Jung Hyeon Cheol Kim Young Joon Choi Jaeho Kim Joon Kim Heung Kyu Lee Graduate School of Medical Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Department of Internal Medicine Seoul National University HospitalSeoul 03080Republic of Korea Department of Biological Sciences KAISTDaejeon 34141Republic of Korea Department of Convergent Research of Emerging Virus Infection Korea Research Institute of Chemical TechnologyDaejeon 34114Republic of Korea.

CD4^(+)T cells play major roles in the adaptive immune system,which requires antigen recognition,costimulation,and cytokines for its elaborate *** studies have provided new insight into the importance of the supramolecular activation cluster(SMAC),which comprises concentric circles and is involved in the amplification of CD4^(+)T cell ***,the underlying mechanism of SMAC formation remains poorly ***,we performed single-cell RNA sequencing of CD4^(+)T cells left unstimulated and stimulated with anti-CD3 and anti-CD28 antibodies to identify novel proteins involved in their *** found that intraflagellar transport 20(IFT20),previously known as cilia-forming protein,was upregulated in antibody-stimulated CD4^(+)T cells compared to unstimulated CD4^(+)T *** also found that IFT20 interacted with tumor susceptibility gene 101(TSG101),a protein that endocytoses ubiquitinated T-cell *** interaction between IFT20 and TSG101 promoted SMAC formation,which led to amplification of AKT-mTOR ***,IFT20-deficient CD4^(+)T cells showed SMAC malformation,resulting in reduced CD4^(+)T cell proliferation,aerobic glycolysis,and cellular ***,mice with T-cell-specific IFT20 deficiency exhibited reduced allergen-induced airway ***,our data suggest that the IFT20-TSG101 axis regulates AKT-mTOR signaling via SMAC formation.

关键词： CD4^(+)T cell Intraflagellar transport 20 Tumor susceptibility gene 101 AKT-mTOR signaling Asthma Supramolecular activation cluster

Improvement of machining quality of copper-plated roll mold by controlling temperature variation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 37-41页

作者： Tae-Jin JE eun-chae JEON Sang-Cheon PARK Doo-Sun CHOI Kyung-Hyun WHANG Myung-Chang KANG Division of Nano-Mechanical Systems Korea Institute of Machinery and Materials Daejeon 305-343 Korea National Core Research Center for Hybrid Materials Solution Pusan National University

Micro prism film used in LCD industry can be manufactured by roll to roll method with copper-plated roll mold. As copper-plated roll mold is getting larger, pitch error is getting severer. The pitch error drops the quality of micro prism film. The main cause of the pitch error was investigated during machining large roll mold whose machined length was 1 200 mm. The temperature of machining system was elevated during machining roll mold, and this elevation induced thermal expansion of the system. The temperature variation around the roll mold also made thermal expansion of the roll mold. The amount of thermal expansion had strong relationship to the amount of pitch error. Therefore, the roll mold was machined after warming-up of machining system and precise temperature controller around copper-plated roll mold was installed, which minimized the temperature variation. Finally, precise micro prism patterns without pitch error were machined on the large roll mold.

关键词：模具加工温度控制器加工质量温度变化镀铜螺距误差热膨胀量微棱镜