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chinese Journal of Integrative Medicine 2024年第7期30卷 616-622页

作者： Eun jin Yang Department of KM Science Research Korea Institute of Oriental MedicineDaejeonYuseong-gu34054Republic of Korea

Objective To examine the effect of combined treatment with Bojungikgi-tang(BJIGT,Buzhong Yiqi Decoction)and riluzole(RZ)in transactive response DNA-binding protein 43(TDP-43)stress granule(SG)cells,a amyotrophic lateral sclerosis(ALS)cell line using transcriptomic and molecular *** TDP-43 SG cells were pretreated with BJIGT(100µg/mL),RZ(50µmol/L),and combined BJIGT(100µg/mL)/RZ(50µmol/L)for 6 h before treatment with lipopolysaccharide(LPS,200µmol/L).cell viability assay was performed to elucidate cell toxicity in TDP-43 Sc cells using a cell-counting kit-8(ccK8)assay *** expression levels of cell death-related proteins,including Bax,caspase 1,cleaved caspase 3 and DJ1 in TDP-43 SG cells were examined by Western blot *** autophagy-related proteins,including pmTOR/mTOR,Lc3b,P62,ATG7 and Bcl-2-associated athanogene 3(Bag3)were investigated using immunofluorescence and immunoblotting *** cell viability assay and Western blot analysis showed that combined treatment with BJIGT and RZ suppressed LPS-induced cell death and expression of cell death-related proteins,including Bax,caspase 1,and DJ1(Pcence and immunoblotting assays showed that combined treatment with BJIGT and RZ reduced LPS-induced formation of TDP-43 aggregates and regulated autophagy-related protein levels,including p62,light chain 3b,Bag3,and ATG7,in TDP-43-expressing cells(Pconclusion The combined treatment of BJIGT and RZ might reduce inflammation and regulate autophagy dysfunction in TDP-43-induced ALS.

关键词： Bojungikgi-tang Buzhong Yiqi Decoction transactive response DNA-binding protein 43 autophagy oxidative stress amyotrophic lateral sclerosis

Acetylacetone-TiO_(2) Promoted Large Area compatible cascade Electron Transport Bilayer for Efficient Perovskite Solar cells

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Energy & Environmental Materials 2024年第2期7卷 221-228页

作者： Hyong Joon Lee jin Kyoung Park jin Hyuck Heo Sang Hyuk Im Department of chemical and Biological engineering Korea University145 Anam-ro Seongbuk-guSeoul 17104Korea

In designing efficient perovskite solar cells(PScs),the selection of suitable electron transport layers(ETLs)is critical to the final device performance as they determine the driving force for selective charge ***_(2)nanoparticles(NPs)based ETLs have been a popular choice for PScs due to superior electron mobility,but their relatively deep-lying conduction band energy levels(EcB)result in substantial potential ***,TiO_(2)NPs establish favorable band alignment owing to shallower EcB,but their low intrinsic mobility and abundant surface trap sites impede the final *** this reason,constructing a cascaded bilayer ETL is highly desirable for efficient PScs,as it can rearrange energy levels and exploit on advantages of an individual *** this study,we prepare SnO_(2)NPs and acetylacetone-modified TiO_(2)(Acac-TiO_(2))NPs and implement them as bilayer SnO_(2)/Acac-TiO_(2)(BST)ETL,to assemble cascaded energy band ***_(2)contributes to rapid charge carrier transport from high electron mobility while Acac-TiO_(2)minimizes band-offset and effectively suppresses interfacial ***,the optimized BST ETL generates synergistic influence and delivers power conversion efficiency(PcE)as high as 23.14%with open-circuit voltage(V_(oc))reaching 1.14 ***,the BST ETL is transferred to a large scale and the corresponding mini module demonstrates peak performance of 18.39%PcE from 25 cm^(2)aperture ***,the BST-based mini module exhibit excellent stability,maintaining 83.1%of its initial efficiency after 1000 h under simultaneous 1 Sun light-soaking and damp heat(85℃/RH 85%)environment.

关键词： acetylacetone large area perovskite solar cells TiO_(2)

Effects of tree size and organ age on variations in carbon,nitrogen,and phosphorus stoichiometry in Pinus koraiensis

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Journal of Forestry Research 2024年第3期35卷 155-165页

作者： Yanjun Wang Guangze jin Zhili Liu center for Ecological Research Northeast Forestry UniversityHarbin 150040People's Republic of China Key Laboratory of Sustainable Forest Ecosystem Management-Ministry of Education Northeast Forestry UniversityHarbin 150040People's Republic of China Northeast Asia Biodiversity Research center Northeast Forestry UniversityHarbin 150040People's Republic of China

carbon(c),nitrogen(N),and phosphorus(P)are of fundamental importance for growth and nutrient dynamics within plant organs and deserve more attention at regional to global ***,our knowledge of how these nutrients vary with tree size,organ age,or root order at the individual level remains *** determined c,N,and P contents and their stoichiometric ratios(i.e.,nutrient traits)in needles,branches,and fine roots at different organ ages(0-3-year-old needles and branches)and root orders(1st-4th order roots)from 64 Pinus koraiensis of varying size(Diameter at breast height ranged from 0.3 to 100 cm)in northeast *** factors were also *** results show that nutrient traits were regulated by tree size,organ age,or root order rather than soil *** a whole-plant level,nutrient traits decreased in needles and fine roots but increased in branches with tree *** the organ level,age or root order had a negative effect on c,N,and P and a positive effect on stoichiometric *** results demonstrate that nutrient variations are closely related to organ-specific functions and ecophysiological processes at an individual *** is suggested that the nutrient acquisition strategy by younger trees and organ fractions with higher nutrient content is for ***,nutrient storage strategy in older trees and organ fractions are mainly for steady *** results clarified the nutrient utilization strategies during tree and organ ontogeny and suggest that tree size and organ age or root order should be simultaneously considered to understand the complexities of nutrient variations.

关键词： Tree size Organ age(or root order) carbon(c) Nitrogen(N) Phosphorus(P) Pinus koraiensis

Simple preparation of c(cS)/g-c_(3)N_(4)/co carbon aerogel and its catalytic performance for ammonium perchlorate

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Defence Technology（防务技术） 2024年第3期33卷 186-196页

作者： Yujie Yan Bo jin Rufang Peng State Key Laboratory of Environment-friendly Energy Materials School of Materials Science and EngineeringSouthwest University of Science and TechnologyMianyang621010China

Biomass chitosan(cS)was used as a template,graphitic phase carbon nitride(g-c_(3)N_(4))with high nitrogen content and certain catalytic activity was used as a dopant,and nano-transition metal cobalt(co)was used as a catalytic center *** carbon aerogel(c(cS)/g-c_(3)N_(4)/co)with a three-dimensional network-like structure was prepared by assembling the three materials through experimental operations such as freeze-drying and high-temperature *** was demonstrated by scanning and transmission characterization that the cS in the carbon aerogel could provide more active sites for the cobalt nanoparticles,and the doping of graphite-phase carbon nitride as a template dispersed the cobalt nanoparticles and changed the conductivity of the *** investigate the catalytic effect of carbon aerogel on ammonium perchlorate(AP),it was investigated by differential thermal analyzer and TG thermal *** carbon aerogel was very effective in catalyzing AP,and the 10 wt% content of the catalyst reduced the AP pyrolysis peak from 703.9 to 595.5 *** to further investigate the synergistic effect of the three materials,further carbon aerogels such as c(cS)/co,g-c_(3)N_(4)/co were prepared and applied to catalyze AP,and the same ratio reduced the AP pyrolysis peak by 98.1℃ and 97.7℃.This result indicates a synergistic effect of the assembly of the three materials.

关键词： g-c_(3)N_(4) chitosan co Ammonium perchlorate Pyrolysis kinetics

Pb induced dislocation defects of Ptco systems: Strain-triggered oxygen reduction reaction for PEMFc

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Nano Research 2024年第4期17卷 2462-2472页

作者： chun jin Qiheng Wang jingjun Liu Beijing Key Laboratory of Electrochemical Process and Technology for Materials Beijing 100029China Beijing University of chemical Technology Beijing 100029China

Design and development of advanced electrocatalysts with high performance and low Pt consumption are crucial for reducing the kinetic energy barrier of the cathode oxygen reduction reaction(ORR)and improving the efficiency of proton exchange membrane fuel cells(PEMFc).In this study,we demonstrate a Pb-modulated Ptco system for efficient ORR,in which the inclusion of Pb in ternary alloys induces dislocation defects due to the significant difference in atomic ***-PtcoPb was confirmed to exhibit significantly higher ORR activity and stability in acidic *** practical PEMFc applications,it outperforms the corresponding commercial Pt/c with a mass activity of 0.58 A·mgPt^(-1),making it a promising alternative to state-of-the-art Pt-based *** combination of experimental results and density functional theory(DFT)calculations offers valuable atomic-level insights into the dislocation *** with a larger atomic radius is located in the lattice stretching region below the dislocation slip plane,forming a structure similar to a cottrell atmosphere,which reduces the dislocation energy and puts the system in a lower energy *** cottrell atmosphere pins the dislocation structure and stabilizes the ternary *** adjusting the amount of added Pb,a moderate level of dislocation density induces a tuned strain effect,thereby enhancing the electrocatalytic mechanism by optimizing the electronic structure of the alloy surface and the adsorption and desorption of oxygen *** work provides valuable insights into the design and development of lattice dislocation defect structures to trigger strain effects for improving ORR performance.

关键词： dislocation defect strain effect Pb-modulated oxygen reduction reaction

MD Simulation of Diffusion Behaviors in collision Welding Processes of Al-cu, Al-Al, cu-cu

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computers, Materials & continua 2024年第6期79卷 3455-3468页

作者： Dingyi jin Guo Wei School of Intelligent Manufacturing Hunan First Normal UniversityChangsha410082China School of Physics and Technology Center for Ion Beam ApplicationHubei Nuclear Solid Physics Key LaboratoryWuhan UniversityWuhan430072China

To investigate the effects of material combinations and velocity conditions on atomic diffusion behavior near collision interfaces,this study simulates the atomic diffusion behavior near collision interfaces in cu-Al,Al-Al and cu-cu combinations fabricated through collision welding using molecular dynamic(MD)*** atomic diffusion behaviors are compared between similar metal combinations(Al-Al,cu-cu)and dissimilar metal combinations(Al-cu).By combining the simulation results and classical diffusion theory,the diffusion coefficients for similar and dissimilar metal material combinations under different velocity conditions are *** effects of material combinations and collision velocity on diffusion behaviors are also *** diffusion behaviors of dissimilar material combinations strongly depend on the transverse velocity,whereas those of the similar material combinations are more dependent on the longitudinal *** findings can provide guidance for optimizing welding parameters.

关键词： Atomic diffusion behavior molecular dynamics collision welding

Oxidation behavior of low-grade vanadiferous titanomagnetite concentrate with high titanium

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Journal of Iron and Steel Research International 2024年第2期31卷 329-341页

作者： jin-sheng Liu Zhen-xing Xing Gong-jin c.eng Xue-yong Ding Xiang-xin Xue School of Metallurgy Northeastern UniversityShenyang110819LiaoningChina Liaoning Key Laboratory of Recycling Science for Metallurgical Resources Shenyang110819LiaoningChina Innovation Research Institute of Vanadium and Titanium Resource Industry Technology Northeastern UniversityShenyang110819LiaoningChina

In order to clarify the oxidation mechanisms and make better use of the low-grade vanadiferous titanomagnetite concentrate with high titanium(LVTc),the oxidation behavior of LVTc was *** results showed that oxidation degree was achieved within 90 min when temperature was not lower than 700°c,and the main phases of the oxidized LVTc consisted of Fe9TiO15,Fe2O3,caSiTiO5 and a small amount of *** temperature is favorable to the formation of *** surface of LVTc gradually becomes rough,with fine particles of needle-like and granular shape appearing on the surface,which finally turn from laminar to creamy,spread out,and are interspersed with many tiny *** phase oxidation paths in LVTc were as follows:(1)Fe2.75Ti0.25O4→Fe9TiO15+Fe2O3;(2)Fe2.75Ti0.25O4→Fe2O3+FeTiO3→Fe2TiO5;(3)FeTiO3→Fe2O3+Fe2Ti3O9→*** is predominantly mesoporous whether oxidized or not,with the pores mainly distributed in the range of 2–40 nm,and the specific surface area of LVTc decreases significantly with increasing temperature.

关键词： Low-grade vanadiferous titanomagnetite concentrate Oxidation degree Phase transformation Micromorphology Oxidation path Pore structure

Toxicity of the disinfectant benzalkonium chloride(c_(14))towards cyanobacterium Microcystis results from its impact on the photosynthetic apparatus and cell metabolism

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Journal of Environmental Sciences 2024年第1期135卷 198-209页

作者： Yunlu Jia Yi Huang jin Ma Shangwei Zhang jin Liu Tianli Li Lirong Song Institute of Hydrobiology Chinese Academy of SciencesWuhan 430072China School of Environmental Studies China University of GeosciencesWuhan 430074China Advanced Interdisciplinary Institute of Environment and Ecology Beijing Normal UniversityZhuhai 519087China

Quaternary ammonium compounds(QAcs)are commonly used in a variety of consumer and commercial products,typically as a component of *** the cOVID-19 pandemic,QAcs became one of the primary agents utilized to inactivate the SARS coV-2 virus on ***,the ecotoxicological effects of QAcs upon aquatic organisms have not been fully *** this study,we examined the effects of a widely used QAc(benzalkonium chloride-c_(14),BAc-14)on two toxigenic Microcystis strains and one non-toxigenic freshwater Microcystis strain and carried out an analysis focused on primary,adaptive and compensatory stress responses at apical(growth and photosynthesis)and metabolic *** analysis revealed that the two toxic Microcystis strains were more tolerant than the non-toxic strain,with 96 hr-Ec_(50)values of 0.70,0.76,and 0.38 mg/L BAc-14 for toxigenic *** FAcHB-905,toxigenic *** FAcHB-469,and non-toxigenic *** FAcHB-908,*** photosynthetic activities of the Microcystis,assessed via F_(v)/F_(m) values,were significantly suppressed under 0.4 mg/L ***,this analysis revealed that BAc-14 altered 14,12,and 8 metabolic pathways in *** FAcHB-905,*** FAcHB-469,and *** FAcHB-908,*** is noteworthy that BAc-14 enhanced the level of extracellular microcystin production in the toxigenic Microcystis strains,although cell growth was not significantly ***,these data show that BAc-14 disrupted the physiological and metabolic status of Microcystis cells and stimulated the production and release of microcystin,which could result in damage to aquatic systems.

关键词： Disinfectants Quaternary ammonium compounds Microcystis cyanotoxin Metabolomics chlorophyll fluorescence

Preparation of calcium carbonate with microstructure and nanostructure from carbide slag for cO_(2) sequestration by using recyclable ammonium chloride

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Particuology 2024年第7期90卷 1-9页

作者： jin Yao Qiuju chen Li Zeng Wenjin Ding Key Laboratory of Ministry of Education for Solid Waste Treatment and Resource Recycle Southwest University of Science and TechnologyMianyang621010China Sichuan engineering Lab of Non-metallic Mineral Powder Modification and High-value Utilization Mianyang621010China School of Architecture and civil engineering Chengdu UniversityChengdu610106China

Based on the composition characteristics of carbide slag and the application of polyvinyl chloride,a method of preparing calcium carbonate with microstructure and nanostructure by using carbide slag as a raw material and ammonium chloride as a leaching agent was *** factors for the preparation of calcium carbonate and the effects of different conditions on the crystal phase,grain size,and morphology of calcium carbonate were systematically *** results showed that the nanosized calcium carbonate was prepared at 60 mL/min,25°c,no additional ammonia,and 60 *** product of spherical vaterite was in accordance with the relevant standards for the industrial precipitation of calcium ***,the reuse of carbonation filtrate was *** crystal phase,grain size,and morphology of the carbonation product could be controlled by adjusting the reaction *** manuscript provided a new idea for resource utilization of carbide slag and preparing nanocalcium carbonate.

关键词： carbide slag Ammonium chloride cyclic utilization Micro and nano structure Product control

Investigation of acoustic attributes based on preference and perceptional acoustics of Korean traditional halls for optimal design solutions

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Building Simulation 2024年第5期17卷 723-738页

作者： Beta Bayu Santika Haram Lee jin Yong Jeon Department of Architectural engineering Hanyang UniversitySeoul 04763R.O.Korea

Immersed in the rich tapestry of traditional culture,Gugak,the traditional Korean music stands as a captivating embodiment of artistic *** study embarked on a comprehensive evaluation of a Gugak hall,employing acoustic measurements,computer simulations,and subjective perception *** evaluation focused on the reverberance,clarity,spatial impression,and preference,unravelling the secrets that shape the immersive Gugak *** intricate computer simulations and auralization,the experience of Gugak performances was meticulously brought to life,allowing exploration under diverse conditions by adjusting stage volume ratios from -20% to+20% and modifying the interior materials,including the walls,ceiling,and lateral *** Gugak halls exhibited relatively low values of reverberation time(RT),early decay time(EDT),and binaural quality index(BQI)the dominant factor influencing the acoustic environment was the effect of sound strength(G).Musical clarity(c80)value did not show an inverse proportionality to the reverberation ***,genre differences between traditional Korean and Western classical music did not significantly affect listeners’perception and satisfaction with regards to reverberance,clarity,and spatial *** a result,Gugak halls can adhere to the same acoustic design criteria as Western orchestra halls,since this study found that people perceived them the same *** this study,sound strength was found to be strongly correlated with perception *** was possible to enhance listeners’perception and preference regarding the acoustic environment through material and structural changes to the sidewalls and *** changes improved the reinforcement of low frequencies and simultaneously enhanced the relative effect of side ***,enhancing the reflection and spatial characteristics of the materials effectively improved listener *** on these findings,an optimal des

关键词： Korean traditional hall acoustical parameters perceptual evaluation acoustic preference stage volume ratio