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FUNCTIONAL NEAR-INFRARED SPECTROSCOPY-BASED ASSESSMENT OF ATTENTION IMPAIRMENTS AFTER TRAUMATIC BRAIN INJURY

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Journal of Innovative Optical Health Sciences 2011年第3期4卷 251-260页

作者： ANNA C.MERZAGORA MARIA T.SCHULTHEIS banu ONARAL MELTEM IZZETOGLU School of Biomedical Engineering Science and Health Systems Drexel University PhiladelphiaPAUSA Department of Psychology Drexel University PhiladelphiaPAUSA

A frequent consequence of traumatic brain injury(TBI)is cognitive impairment,which results in significant disruption of an individual's everyday *** date,most clinical rehabilitation interventions still rely on behavioral observation,with little or no quantitative information about physiological changes produced at the brain *** brain imaging has been extensively used in the study of cognitive impairments following ***,its applications to rehabilitation have been *** is due in part to the expensive or invasive nature of these *** objective of this study is to apply functional near-infrared spectroscopy(fNIR)to the assessment of attention impairments following *** provides a localized measure of prefrontal hemodynamic activation,which is susceptible to TBI,and it does so in a noninvasive,affordable and wearable way,thus partially overcoming the limitations of other *** included 5 TBI subjects and 11 healthy *** activation measurements were collected during a target categorization *** differences were found in the hemodynamic response between healthy and TBI *** particular,the elicited responses exhibited reduced amplitude in the TBI ***,the results providefirst evidence of the ability of fNIR to reveal differences between TBI and healthy subjects in an attention *** is therefore a promising neuroimaging technique in thefield of *** use of fNIR in neurorehabilitation applications would benefit from its noninvasiveness and cost-effectiveness and the neurophysiological information obtained through the evaluation of the hemodynamic activation could provide invaluable information to guide the choice of intervention.

关键词： fNIR attention traumatic brain injury NIRS TBI

Comparison of visual acuity, refractive results and complications of femtosecond laser with mechanical microkeratome in LASIK

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International Journal of Ophthalmology(English edition) 2013年第3期6卷 350-355页

作者： Cemile banu Cosar Tansu Gonen Murat Moray Asim Bozkurt Sener Department of Ophthalmology Acibadem University Department of Ophthalmology Namlk Kemal University Eye Clinic Acibadem Bursa Hospital Eye Clinic Acibadem Maslak Hospital

AIM: To compare the outcomes of laser in situ keratomileusis (LASIK) performed with a femtosecond laser (Femtec, Technolas Perfect Vision GmbH, Germany) versus a mechanical microkeratome (Hansatome, Bausch and Lomb, USA) for the correction of myopia and astigmatism. ·METHODS: In this retrospective study, patients who had undergone LASIK using the 80 -kHz Femtec femtosecond laser were compared to age- and refraction- matched patients in whom the Hansatome microkeratome was used. Refractive and visual results 1 month and 3 months postoperatively, and complication rates were compared between the two groups. ·RESULTS: A total of 280 eyes were analyzed (140 in each group). At 3 months postoperatively in the Femtec vs Hansatome group, spherical equivalent refraction was within ±1.00D of emmetropia in 140 vs 138 eyes (P = 0.498), the cylinder was within ±0.50D in 137 vs 139 eyes (P =0.622), and the UDVA was 20/20 or better in 136 vs 137 eyes (P =0.724), respectively. There was no statistically significant difference in the complication rates between the two groups (P =0.099). ·CONCLUSION: LASIK performed both with Femtec femtosecond laser and Hansatome microkeratome achieved satisfactory refractive and visual results at 3 months postoperatively, without significant differences in efficacy, safety, and complication rates between the two procedures.

关键词： laser in situ keratomileusis femtosecond laser Femtec microkeratome Hansatome

An incidental case of triple gallbladder

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World Journal of Gastroenterology 2007年第13期13卷 2004-2006页

作者： banu Alicioglu Department of Radiology Trakya University School of Medicine Edirne 22030 Turkey

Triplication of the gallbladder is a very rare congenital anomaly of the biliary tract; there are only eleven reported cases to date. Gallbladder multiplications are not likely to be discovered unless associated with cholelithiasis, sludge, cholecystitis and carcinoma. Here we report an incidentally diagnosed triplicate gallbladder in a patient with sigmoid diverticulitis; two of the triplicate gallbladder were demonstrated with ultrasound and computed tomography, and an additional galballder was found at surgery.

关键词： Biliary system Biliary tract imaging Multiplegallbladders Triple gallbladder

Ameliorating effect of Semecarpus anacardium *** milk extract on altered glucose metabolism in high fat diet STZ induced type 2 diabetic rats

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Asian Pacific Journal of Tropical Medicine 2012年第12期5卷 956-961页

作者： Haseena banu Hedayathullah Khan Kaladevi Siddhi Vinayagam Shanthi Palanivelu Sachdanandam Panchanadham Department of Medical Biochemistry DR.A.L.M.P-G.I.B.M.S.University of MadrasTaramani CampusChennai-600113India

Objective:To explore the protective effect of the drug Semecarpus anacardium(***) on altered glucose metabolism in diabetic ***:Type 2 diabetes mellitus was induced by feeding rats with high fat diet followed by single intraperitoneal injection of streptozotocin (STZ)(35 mg/kg b.w.).Seven days after STZ induction,diabetic rats received nut milk extract of *** *** milk extract orally at a dosage of 200 mg/kg daily for 4 *** effect of nut milk extract of *** on blood glucose,plasma insulin,glucose metabolising enzymes and GSK were ***:Treatment with SA extract showed a significant reduction in blood glucose levels and increase in plasma insulin levels and also increase in HOMA-βand decrease in HOMA -*** drug significantly increased the activity of glycolytic enzymes and glucose-6-phosphate dehydrogenase activity and increased the glycogen content in liver of diabetic rats while reducing the activities of gluconeogenic *** drug also effectively ameliorated the alterations in GSK-3 mRNA ***:Overall,the present study demonstrates the possible mechanism of glucose regulation of *** suggestive of its therapeutic potential for the management of diabetes mellitus.

关键词： Semecarpus anacardium Streptozotocin Carbohydrate metabolism Insulin signalling

Subthreshold micropulse laser versus intravitreal anti-VEGF for diabetic macular edema patients with relatively better visual acuity

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International Journal of Ophthalmology(English edition) 2020年第10期13卷 1606-1611页

作者： Sezen Akkaya banu Acιkalιn Yusuf Emre Dogan Fatih Coban Departmant of Ophthalmology Saglιk Bilimleri UniversityFSM Training and Research Hospitallstanbul 34752Turkey

AIM:To compare the effects of yellow(577 nm)subthreshold micropulse laser(SML)and intravitreal(IV)anti-vascular endothelial growth factor(VEGF)treatment in patients with diabetic macular edema(DME)with relatively better visual acuity[best corrected visual acuity(BCVA)≤0.15 log MAR].METHODS:The medical records of 76 eyes of 47 patients underwent IV(0.5 mg)anti-VEGF injection or SML for the DME with relatively better BCVA were *** IV group received three consecutive monthly IV anti-VEGF injections,then were retreated as *** laser treatment group was treated at baseline and 3 mo,and then retreated at 6 and 9 mo if *** participants were followed up for one *** mean BCVA and mean central macular thickness(CMT)values changes over the follow-up were ***:Twenty-four and 23 patients were assigned to the SML and IV subgroups,*** mean number of treatments was 3.64±0.76 in SML group and 5.85±1.38 in IV group(P<0.05).The subgroups were similar with regard to the mean BCVA score at baseline and at the 1st and 3rd months,but the score of SML group was better than that of IV group at the 6th,9th,and 12th months(P<0.05).The decrease in the mean CMT values from baseline values was higher in SML group at the 6th,9th,and 12th months(P<0.05).CONCLUSION:Yellow SML treatment is superior to IV anti-VEGF injection in DME patients with relatively better BCVA for increasing visual acuity and decreasing CMT at 6,9,and 12 *** can be a good alternative first-line therapy for DME with BCVA≤0.15 log MAR.

关键词： diabetic macular edema subthreshold micropulse laser anti-VEGF injection

Angiotensin Ⅱ stimulates expression of transcription factors c-Jun and c-Fos in cyclosporine induced human gingival fibroblasts

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BIOCELL 2013年第3期37卷 71-76页

作者： Tamilselvan SUBRAMANI Suresh RAO Kamatchiammal SENTHILKUMAR Soundararajan PERIASAMY Noorjahan banu ALITHEEN Department of Cell and Molecular Biology Faculty of Biotechnology and Biomolecular SciencesUniversiti Putra MalaysiaSerdangMalaysia. Department of Periodontics Faculty of Dental ScienceSri Ramachandra UniversityChennaiIndia. Virology Division National Environmental Engineering Research InstituteChennaiIndia. Department of Nephrology Faculty of MedicineSri Ramachandra UniversityChennaiIndia.

The present study demonstrates that the expression of c-Jun and c-Fos are elevated in gingival fibroblast cells treated with angiotensin Ⅱ and *** healthy human gingival tissues were collected and gingival fibroblasts were isolated and *** used RT-PCR and Western blot analysis to identify the expression of c-Jun and c-Fos in cyclosporine and angiotensin II treated human gingival fibroblast *** found that angiotensin Ⅱ in combination with cyclosporine induces c-Jun and c-Fos expressions significantly;however,the angiotensin Ⅱ antagonist losartan inhibits the expression of c-Jun and c-Fos(p<0.01).The data suggest that angiotensin Ⅱ in combination with cyclosporine modulates the expression of c-Jun and c-Fos in human gingival fibroblast cells.

关键词： angiotensin c-Jun c-Fos transcription factor cyclosporine gingival overgrowth.

Effect of Boron and Heat Treatment on Mechanical Properties of White Cast Iron for Mining Application

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Journal of Iron and Steel Research International 2011年第11期18卷 31-39页

作者： Havva Kazdal Zeytin Hakan Yildirim banu Berme Selim Duduoglu Gürkan Kazdal Adem Deniz TUBITAK MRC Duduoglu Steel Casting Industry and Trade Inc Co TuBITAK MRC Materials Institute Chemistry Metallurgy Faculty Istanbul Technical University

Heat treatment methods were applied to white cast iron for improving the impact and wear resistance. Additionally, chemical composition optimization was made. Furthermore, the effect of boron addition on such applica- tions was investigated. Samples were investigated by using optical and electron microscope methods. Hardness, wear and impact tests were conducted. The results showed that the secondary carbides in the standard alloy were iron-enriched, needle-like carbides M3C when the boron-added alloy contained Fe23 （C, B）6 type, globular secondary carbides. It was concluded that heat treatment B provided higher wear and hardness properties, compared to the stand- ard heat treatment. Optimum mechanical properties were obtained by lower destabilisation temperatures and increasing temperature reduced the wear resistance and hardness.

关键词： white cast iron mining application impact resistance wear toughness

Effect of Helicobacter pylori eradication on serum ghrelin and obestatin levels

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World Journal of Gastroenterology 2013年第15期19卷 2388-2394页

作者： Celal Ulasoglu banu Isbilen Levent Doganay Filiz Ozen Safak Kiziltas Ilyas Tuncer Department of Gastroenterology Istanbul Medeniyet UniversityGoztepe Education and Research Hospital34470 IstanbulTurkey Department of Biochemistry Istanbul Medeniyet UniversityGoztepe Education and Research Hospital34470 IstanbulTurkey Medical Genetics Istanbul Medeniyet UniversityGoztepe Education and Research Hospital34470 IstanbulTurkey

AIM: To investigate changes in serum ghrelin and obestatin levels before and after Helicobacter pylori (H. pylori ) eradication. METHODS: A total of 92 patients presenting with symptoms of dyspepsia were enrolled in the study. Upper endoscopy was performed on all patients and used to diagnose H. pylori infection according to the presence of characteristic histopathological findings; seventy patients were diagnosed with H. pylori infection and the remaining 22 non-infected patients were classified as healthy controls. H. pylori eradication was accomplished by administering the classical triple therapy drug regimen, consisting of lansoprazole 30 mg bid , amoxicillin 1 g bid , and clarithromycin 500 mg tid for 14 d. The eradication of H. pylori was assessed with C14-urea breath test, which was performed at eight weeks after treatment. Levels of serum active ghrelin and obestatin were assessed at beginning of the study (prior to treatment) and after eight weeks. The levels were comparatively analyzed between the H. pylori negative control group, the H. pylori eradicated group, and the H. pylori non-eradicated group. RESULTS: A total of 92 patients, 50 females and 42 males with a mean age of 38.2 ± 11.9 years (range: 19-64), were analyzed. H. pylori eradication success was achieved in 74.3% (52/70) of H. pylori positive patients. The initial levels of ghrelin in the H. pylori positive and control cases were 63.6 ± 19.8 pg/mL and 65.1 ± 19.2 pg/mL (P=0.78), respectively, and initial obestatin levels were 771±427 pg/mL and 830 ± 296 pg/mL (P=0.19), respectively. The difference between the initial levels and the week 8 levels of ghrelin and obestatin in the control group was insignificant [4.5% (P=0.30) and -0.9% (P=0.65), respectively]. The difference between the initial and week 8 levels of ghrelin and obestatin in the H. pylori non-eradicated group were also insignificant [0.9% (P=0.64) and 5.3% (P=0.32), respectively]. The H. pylori eradicated group had a greater change

关键词： Ghrelin Obestatin Helicobacter pylori Gastric peptides Appetite

Bio-inspired cryptosystem on the reciprocal domain:DNA strands mutate to secure health data

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Frontiers of Information Technology & Electronic Engineering 2021年第7期22卷 940-956页

作者： S.AASHIQ banu Rengarajan AMIRTHARAJAN School of Electrical&Electronics Engineering SASTRA Deemed UniversityThanjavur 613401India

Healthcare and telemedicine industries are relying on technology that is connected to the *** health data are more prone to cyber attacks because of the treasure trove of personal data they *** necessitates protection of digital medical images and their secure *** this paper,an encryption technique based on DNA mutated with Lorenz and Lüchaotic attractors is employed to generate high pseudo-random key *** proposed chaos-DNA cryptic system operates on the integer wavelet transform(IWT)domain and a bio-inspired crossover,mutation unit for enhancing the confusion and diffusion phase in an approximation ***,an XOR operation is performed with a quantised chaotic set from the developed combined *** algorithm attains an average entropy of 7.9973,near-zero correlation with an NPCR of 99.642%,a UACI of 33.438%,and a keyspace of 10~(203).Further,the experimental analyses and NIST statistical test suite have been designed such that the proposed medical image encryption technique has the potency to withstand any statistical,differential,and brute force attacks.

关键词： Medical image encryption DNA Chaotic attractors Crossover Mutation e-Healthcare