FUNCTIONAL NEAR-INFRARED SPECTROSCOPY-BASED ASSESSMENT OF ATTENTION IMPAIRMENTS AFTER TRAUMATIC BRAIN INJURY

作     者：ANNA C.MERZAGORA MARIA T.SCHULTHEIS BANU ONARAL MELTEM IZZETOGLU 

作者机构：School of Biomedical Engineering Science and Health SystemsDrexel University PhiladelphiaPAUSA Department of PsychologyDrexel University PhiladelphiaPAUSA 

出 版 物：《Journal of Innovative Optical Health Sciences》 (创新光学健康科学杂志（英文）)

年 卷 期：2011年第4卷第3期

页      面：251-260页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：fNIR attention traumatic brain injury NIRS TBI 

摘      要：A frequent consequence of traumatic brain injury(TBI)is cognitive impairment,which results in significant disruption of an individual s everyday *** date,most clinical rehabilitation interventions still rely on behavioral observation,with little or no quantitative information about physiological changes produced at the brain *** brain imaging has been extensively used in the study of cognitive impairments following ***,its applications to rehabilitation have been *** is due in part to the expensive or invasive nature of these *** objective of this study is to apply functional near-infrared spectroscopy(fNIR)to the assessment of attention impairments following *** provides a localized measure of prefrontal hemodynamic activation,which is susceptible to TBI,and it does so in a noninvasive,affordable and wearable way,thus partially overcoming the limitations of other *** included 5 TBI subjects and 11 healthy *** activation measurements were collected during a target categorization *** differences were found in the hemodynamic response between healthy and TBI *** particular,the elicited responses exhibited reduced amplitude in the TBI ***,the results providefirst evidence of the ability of fNIR to reveal differences between TBI and healthy subjects in an attention *** is therefore a promising neuroimaging technique in thefield of *** use of fNIR in neurorehabilitation applications would benefit from its noninvasiveness and cost-effectiveness and the neurophysiological information obtained through the evaluation of the hemodynamic activation could provide invaluable information to guide the choice of intervention.