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Aerosol jet printing of surface acoustic wave microfluidic devices

Microsystems & Nanoengineering 2024年第1期10卷 231-242页

作者： Joseph Rich b.ian cole Teng Li brandon Lu Hanyu Fu brittany N.Smith Jianping Xia Shujie Yang Ruoyu Zhong James L.Doherty Kanji Kaneko Hiroaki Suzuki Zhenhua Tian Aaron D.Franklin Tony Jun Huang Department of biomedical Engineering Duke UniversityDurhamNC 27708USA Department of Electrical and Computer Engineering Duke UniversityDurhamNC 27708USA Department of Mechanical Engineering Virginia Polytechnic Institute and State UniversityBlacksburgVA 24061USA Thomas Lord Department of Mechanical Engineering and Materials Science Duke UniversityDurhamNC 27708USA Deptartment of Precision Mechanics Faculty of Science and EngineeringChuo UniversityTokyo 112-8551Japan Department of Chemistry Duke UniversityDurhamNC 27708USA

The addition of surface acoustic wave(SAW)technologies to microfluidics has greatly advanced lab-on-a-chip applications due to their unique and powerful attributes,including high-precision manipulation,versatility,integrability,biocompatibility,contactless nature,and rapid ***,the development of SAW microfluidic devices is limited by complex and time-consuming micro/nanofabrication techniques and access to cleanroom facilities for multistep photolithography and vacuum-based *** simplify the fabrication of SAW microfluidic devices with customizable dimensions and functions,we utilized the additive manufacturing technique of aerosol jet *** successfully fabricated customized SAW microfluidic devices of varying materials,including silver nanowires,graphene,and poly(3,4-ethylenedioxythiophene)polystyrene sulfonate(PEDOT:PSS).To characterize and compare the acoustic actuation performance of these aerosol jet printed SAW microfluidic devices with their cleanroom-fabricated counterparts,the wave displacements and resonant frequencies of the different fabricated devices were directly measured through scanning laser Doppler ***,to exhibit the capability of the aerosol jet printed devices for lab-on-a-chip applications,we successfully conducted acoustic streaming and particle concentration ***,we demonstrated a novel solution-based,direct-write,single-step,cleanroom-free additive manufacturing technique to rapidly develop SAW microfluidic devices that shows viability for applications in the fields of biology,chemistry,engineering,and medicine.

关键词： printing wave fluid

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Intramedullary bone pedestal formation contributing to femoral shaft fracture nonunion:A case report and review of the literature

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World Journal of Orthopedics 2022年第5期13卷 528-537页

作者： Charles b Pasque Alexander J Pappas Chad A cole Jr Department of Orthopaedic Surgery and Rehabilitation University of Oklahoma College of MedicineOklahoma CityOK 73104United States University of Colorado School of Medicine AuroraCO 80045United States

bACKGROUND Femoral shaft fracture is a commonly encountered orthopedic injury that can be treated operatively with a low overall delayed/nonunion *** the case of delayed union after antegrade or retrograde intramedullary nail fixation,fracture dynamization is often attempted *** after dynamization has been shown to occur due to infection and other aseptic *** present a unique case of diaphyseal femoral shaft fracture nonunion after dynamization due to intramedullary cortical bone pedestal formation at the distal tip of the *** SUMMARY A 37-year-old male experienced a high-energy trauma to his left thigh after coming down hard during a motocross *** was consistent with an isolated,closed,left mid-shaft femur *** was initially managed with reamed antegrade intramedullary nail fixation but had continued thigh *** at four months demonstrated no evidence of fracture union and failure of the distal locking screw,and dynamization by distal locking screw removal was *** patient continued to have pain eight months after the initial procedure and 4 mo after dynamization with serial radiographs continuing to demonstrate no evidence of fracture *** decision was made to proceed with exchange nailing for aseptic fracture *** the exchange procedure,an obstruction was encountered at the distal tip of the failed nail and was confirmed on magnified fluoroscopy to be a pedestal of cortical bone in the *** obstruction required further distal reaming.A longer and larger diameter exchange nail was placed without difficulty and without a distal locking screw to allow for dynamization at the fracture ***-operative radiographs showed proper fracture and hardware *** was subsequently radiographic evidence of callus formation at one year with subsequent fracture consolidation and resolution of thigh pain at eighteen *** The risk of fracture nonunion caused by int

关键词： Nonunion Femoral shaft fracture Diaphysis Fracture fixation Antegrade intramedullary nail Case report

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φ-meson photoproduction off the protons by using linearly polarized photons in the mid- to higher-t regimes at threshold energies

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Chinese Physics C 2009年第12期33卷 1349-1353页

作者： Julian Salamanca Philip L. cole Idaho State University Department of Physics Pocatello ID 83209-8106 USA Thomas Jefferson National Laboratory. Newport News VA 23606 USA

Observables from vector meson photoproduction by linearly-polarized photons can be expressed in term of bilinear combinations of helicity amplitudes parameterized by the Spin Density Matrix Elements （SDMEs）. These SDMEs give straightforward relations for understanding the nature of the parity exchange at threshold energies, as well as for extracting signatures of the Okubo-Zweig-Iizuka violation. This paper will show preliminary measurements of SDMEs for γp →φp in the photon energy range of 1.7 to 1.9 GeV （momentum transfer squared t range of -1.2 to -0.25 GeV2） and 1.9 to 2.1 CeV （t range of -1.4 to -0.25 GeV2） from the g8b experimental data collected in the summer of 2005 in the Hall b of Jefferson Lab.

关键词： photoproduction of Ф-mesons linearly-polarized photons polarization observables

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The Ornithodolite as a tool to quantify animal space use and habitat selection: a case study with birds diving in tidal waters

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Integrative Zoology 2019年第1期14卷 4-16页

作者： Emma-Louise cole James J WAGGITT Anders HEDENSTROM Marco PianO Mark D.HOLTON Luca bÖRGER Emily L.C.SHEPARD Department of biosciences Swansea UniversitySwanseaUK School of Ocean Sciences Bangor UniversityMenai BridgeUK Department of biology Lund UniversityEcology BuildingSweden Centre for Applied Marine Sciences Bangor UniversityMenai BridgeUK

Animal-attached technologies can be powerful means to quantify space use and behavior;however,there are also ethical implications associated with capturing and instrumenting ***,tagging approaches are not necessarily well-suited for examining the movements of multiple individuals within specific,local areas of ***,we assess a method of quantifying animal space use based on a modified theodolite with an inbuilt laser *** a database of>4200 tracks of migrating birds,we show that detection distance in-creases with bird body mass(range 5 g to>10 kg).The maximum distance recorded to a bird was 5500 m and measurement error was≤5 m for targets within this distance range:a level comparable to methods such as GPS *** go on to present a case study where this method was used to assess habitat selection in seabirds operating in dynamic coastal waters close to a tidal *** positional data with outputs from a hydrographic model revealed that great cormorants(Phalacrocorax carbo)appeared to be highly selective of current characteristics in space and time,exploiting areas where mean current speeds werebulent energy levels were *** birds also oriented into tidal currents during *** together,this suggests that collision risks are low for cormorants at this site,as the 2 conditions avoided by cormorants(high mean current speeds and turbulence levels)are associated with operational tidal ***-all,we suggest that this modified theodolite system is well-suited to the quantification of movement in small areas associated with particular development strategies,including sustainable energy devices.

关键词： GPS habitat use movement ecology seabird tidal turbine

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液相色谱-质谱检测3种不同属新鲜黄芩中8种成分

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食品科学 2014年第4期35卷 131-136页

作者：董喆黄湘鹭曹进张庆生肖盛元 ian b.cole Susan J.Murch 中国食品药品检定研究院食品化妆品检定所北京100050 北京理工大学生命科学院北京100081 卑诗大学奥根分校科学与艺术学院化学系

目的:利用在线的方式,建立对3个属的新鲜黄芩样品中8种成分(褪黑素、5-羟色胺、吲哚-3-乙酸、金丝桃素、黄芩苷、黄芩素、汉黄芩苷、野黄芩苷)的液相色谱-质谱联用测定方法。方法:植物样品的匀浆与适量填料混合后,被填入相应的样品仓,... 详细信息

目的:利用在线的方式,建立对3个属的新鲜黄芩样品中8种成分(褪黑素、5-羟色胺、吲哚-3-乙酸、金丝桃素、黄芩苷、黄芩素、汉黄芩苷、野黄芩苷)的液相色谱-质谱联用测定方法。方法:植物样品的匀浆与适量填料混合后,被填入相应的样品仓,通过杂质去除,目标物质富集洗脱等步骤,用于成分测定。结果:测定黄芩样品中8种成分,方法的检出限及定量限条件的回收率均大于90%,重复性及稳定性相对标准偏差不大于3.1%。结论:可以用于对黄芩原料中功效成分的评价。

关键词：液相色谱-质谱法中国黄芩北美黄芩南美黄芩

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Rail temperature variation under heavy haul operations

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Railway Engineering Science 2022年第2期30卷 148-161页

作者： Chris bosomworth Maksym Spiryagin Sanath Alahakoon Colin cole ben Sneath bruce Makin Centre for Railway Engineering Central Queensland UniversityRockhampton 4702Australia Australasian Centre for Rail Innovation Canberra 2601Australia ARC Infrastructure Perth 6105Australia

There currently does not exist in industry a reliable method for the detection of rail foot *** their head-based counterparts,foot flaws result in broken rail with potentially catastrophic consequences.A proposed area of research for the detection of these flaws is thermography,a non-contact method of measuring and analysing infrared emissions from an object under *** industry,active excitation thermography is the most common,requiring an excitation *** paper will present a temperature measurement system and a method of transient temperature extraction from the running rails for the effects of a passing train to evaluate heat transfer in the practical rail *** outcomes of these results will provide future direction in the development of a rail heat transfer model and determine if train passage provides enough active excitation for a thermography-based detection technique.

关键词： Rail heat transfer Rail foot flaws Field temperature measurement Transient temperature extraction

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Confirmed Envenomation by Androctonus amoreuxi (Egyptian Yellow Fat Tail Scorpion)

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Case Reports in Clinical Medicine 2023年第4期12卷 88-92页

作者： Robert cole Pueringer Kirk Hughes Isaac Yelkin Jon b. cole Travis D. Olives Minnesota Poison Control System Minneapolis USA Department of Emergency Medicine Essentia Health Duluth USA Department of Emergency Medicine Hennepin Healthcare Minneapolis USA

In the United States, envenomations by native scorpion species such as Centruroides are common and generally well-tolerated. On the contrary, Androctonus species envenomations are exceedingly rare outside the Middle East and North Africa but are particularly deadly. We report a case of envenomation by an Egyptian Yellow Fat Tail (Androctonus amoreuxi) scorpion and the subsequent clinical course. A hobbyist and dangerous scorpion collector was stung by his pet Androctonus amoreuxi, purchased online. Our patient rapidly developed severe localized pain followed by systemic effects, including tachycardia, hypertension, tachypnea, anxiety, GI symptoms, diplopia, dyspnea, profound myalgias, and intense paresthesias. Ultimately, he was diagnosed with a grade 2-to-3 scorpion envenomation based upon evidence of autonomic hyperactivity and cranial nerve dysfunction. He never progressed to cardiopulmonary compromise;neither dobutamine nor antivenom was administered, and he improved with supportive care alone. Case details were verified in person and via electronic medical record review.

关键词： Androctonus amoreuxi Fat Tail Scorpion Envenomation

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Variation in the life-history traits of a Schilbid catfish,Clupisoma garua (Hamilton, 1822) in the coastal waters of southern bangladesh

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Chinese Journal of Oceanology and Limnology 2017年第5期35卷 1189-1196页

作者： Muhammad Abu bakar SIDDIK Md Reaz CHAKLADER Md Abu HANIF Ashfaqun NAHAR Ilham ILHAM Anthony cole Ravi FOTEDAR Department of Fisheries biology and Genetics Patuakhali Science and Technology University Patuakhali-8602 Bangladesh Department of Marine Fisheries and Oceanography Patuakhali Science and Technology University Patuakhali-8602 Bangladesh Department of Aquatic Resources and Management Jakarta Fisheries University Jl. A UP Pasar Minggu Jakarta Selatan 12520 Indonesia Department of Environment and Agriculture Curtin University 1 Turner Avenue Bentley VIA 6102 Australia

For the first time, the present study reports the life-history traits, comprising length-frequency distribution （LFD）, sex ratio （SR）, length-weight relationships （LWRs）, condition factors （CFs）, and relative growth （WR）, of Clupisoma garua in the coastal waters of bangladesh. A total of 150 specimens ranging from 8.60 to 25.20 cm total length （TL） and 4.26 to 128.80 g body weight （bW） were collected using traditional fishing gear from August 2013 to July 2014. The overall sex ratio of males to females in the study did not differ significantly from the expected value of 1：1 （χ2=0.96, P〈0.05） but there were significant sex differences （P〈0.05） in the intercepts and slopes of graphs characterizing traits in C. garua. The calculated b values for the LWRs were 2.955, 2.893 and 2.927 for males, females and combined sexes, respectively, and there was negative allometric growth in all cases （b〈3）. The condition factors （KA, KF, KrR） and relative growth （WR） also did not differ significantly （P〈0.05） between the sexes. This study provides a useful tool for fishery specialists to evaluate the relative condition of fish and to initiate early management strategies and regulations for the sustainable management of the remaining stocks of this species in the entire coastal region of southern bangladesh.

关键词： size frequency length-weight sex ratio allometric growth Clupisoma garua

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STCF conceptual design report (Volume 1): Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai L.P.An R.Aliberti Q.An X.Z.bai Y.bai O.bakina A.barnyakov V.blinov V.bobrovnikov D.bodrov A.bogomyagkov A.bondar I.boyko Z.H.bu F.M.Cai H.Cai J.J.Cao Q.H.Cao X.Cao Z.Cao Q.Chang K.T.Chao D.Y.Chen H.Chen H.X.Chen J.F.Chen K.Chen L.L.Chen P.Chen S.L.Chen S.M.Chen S.Chen S.P.Chen W.Chen X.Chen X.F.Chen X.R.Chen Y.Chen Y.Q.Chen H.Y.Cheng J.Cheng S.Cheng T.G.Cheng J.P.Dai L.Y.Dai X.C.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.Z.Ding L.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.J.Du Z.G.Du L.M.Duan D.Epifanov Y.L.Fan S.S.Fang Z.J.Fang G.Fedotovich C.Q.Feng X.Feng Y.T.Feng J.L.Fu J.Gao Y.N.Gao P.S.Ge C.Q.Geng L.S.Geng A.Gilman L.Gong T.Gong b.Gou W.Gradl J.L.Gu A.Guevara L.C.Gui A.Q.Guo F.K.Guo J.C.Guo J.Guo Y.P.Guo Z.H.Guo A.Guskov K.L.Han L.Han M.Han X.Q.Hao J.b.He S.Q.He X.G.He Y.L.He Z.b.He Z.X.Heng b.L.Hou T.J.Hou Y.R.Hou C.Y.Hu H.M.Hu K.Hu R.J.Hu W.H.Hu X.H.Hu Y.C.Hu J.Hua G.S.Huang J.S.Huang M.Huang Q.Y.Huang W.Q.Huang X.T.Huang X.J.Huang Y.b.Huang Y.S.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia Z.K.Jia H.b.Jiang J.Jiang S.Z.Jiang J.b.Jiao Z.Jiao H.J.Jing X.L.Kang X.S.Kang b.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.Lei E.Levichev C.H.Li C.Li D.Y.Li F.Li G.Li G.Li H.b.Li H.Li H.N.Li H.J.Li H.L.Li J.M.Li J.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.H.Li S.Li T.Li W.J.Li X.Li X.H.Li X.Q.Li X.H.Li Y.Li Y.Y.Li Z.J.Li H.Liang J.H.Liang Y.T.Liang G.R.Liao L.Z.Liao Y.Liao C.X.Lin D.X.Lin X.S.Lin b.J.Liu C.W.Liu D.Liu F.Liu G.M.Liu H.b.Liu J.Liu J.J.Liu J.b.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu S.b.Liu T.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu Z.Q.Liu Z.Y.Liu Z.W.Liu I.Logashenko Y.Long C.G.Lu J.X.Lu N.Lu Q.F.Lü Y.Lu Y.Lu Z.Lu P.Lukin F.J.Luo T.Luo X.F.Luo Y.H.Luo H.J.Lyu X.R.Lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko Z.X.Meng R.Mitchell A.Nefediev Y.Nefedov S.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei H.P.Peng L.Peng X.Y.Peng X.J.Peng K.Peters S.Pivovarov E.Pyata b.b.Qi Y.Q.Qi W.b.Qian Y.Qian C.F.Qiao J.J.Qin J.J.Qin L.Q.Qin X.S.Qin T.L.Qiu J.Rademacker C.F.Redmer H.Y.Sang Anhui University Hefei 230039China beihang University Beijing 100191China budker Institute of Nuclear Physics Novosibirsk 630090Russia CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central China Normal University Wuhan 430079China Central South University Changsha 410083China China University of Geosciences Wuhan 430074China China University of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de Lausanne(EPFL) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of Technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High Energy Physics Center Chung-Ang UniversitySeoul 06974Korea Higher School of Economy 11 Pokrovsky bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive Technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of Science and Technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the bEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STCF project in China is under development with an extensive R&D *** document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STCF detector conceptual design

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Methodologies for preparation of prokaryotic extracts for cell-free expression systems

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Synthetic and Systems biotechnology 2020年第4期5卷 252-267页

作者： Stephanie D.cole Aleksandr E.Miklos Abel C.Chiao Zachary Z.Sun Matthew W.Lux US Army Combat Capabilities Development Command Chemical biological Center 8567 Ricketts Point RoadAberdeen Proving GroundMD21010USA Division of biology and biological Engineering California Institute of TechnologyPasadenaCAUSA Synvitrobio Inc. San FranciscoCAUSA 8567 Ricketts Point Road Bldg E3549 Room B140APGMD21010USA

Cell-free systems that mimic essential cell functions,such as gene expression,have dramatically expanded in recent years,both in terms of applications and widespread *** we provide a review of cell-extract methods,with a specific focus on prokaryotic ***,we describe the diversity of Escherichia coli genetic strains available and their corresponding *** then trace the history of cell-extract methodology over the past 20 years,showing key improvements that lower the entry level for new ***,we survey the rise of new prokaryotic cell-free systems,with associated methods,and the opportunities ***,we use this historical perspective to comment on the role of methodology improvements and highlight where further improvements may be possible.

关键词： Cell-free systems Cell-free expression Cell-free extract Synthetic biology Methods

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