Aerosol jet printing of surface acoustic wave microfluidic devices
作者机构:Department of Biomedical EngineeringDuke UniversityDurhamNC 27708USA Department of Electrical and Computer EngineeringDuke UniversityDurhamNC 27708USA Department of Mechanical EngineeringVirginia Polytechnic Institute and State UniversityBlacksburgVA 24061USA Thomas Lord Department of Mechanical Engineering and Materials ScienceDuke UniversityDurhamNC 27708USA Deptartment of Precision MechanicsFaculty of Science and EngineeringChuo UniversityTokyo 112-8551Japan Department of ChemistryDuke UniversityDurhamNC 27708USA
出 版 物:《Microsystems & Nanoengineering》 (微系统与纳米工程(英文))
年 卷 期:2024年第10卷第1期
页 面:231-242页
核心收录:
学科分类:08[工学] 0804[工学-仪器科学与技术] 0805[工学-材料科学与工程(可授工学、理学学位)] 081201[工学-计算机系统结构] 0812[工学-计算机科学与技术(可授工学、理学学位)]
基 金:support from the National Science Foundation(CMMI-2104526,CMMI-2243771,and CMMI-2104295) the Department of Energy(DE-NE0009187) the National Institutes of Health(R01GM132603,R01GM144417,and R01GM135486) supported by the National Science Foundation Graduate Research Fellowship under Grant No.2139754 for J.R.and B.S
摘 要:The addition of surface acoustic wave(SAW)technologies to microfluidics has greatly advanced lab-on-a-chip applications due to their unique and powerful attributes,including high-precision manipulation,versatility,integrability,biocompatibility,contactless nature,and rapid ***,the development of SAW microfluidic devices is limited by complex and time-consuming micro/nanofabrication techniques and access to cleanroom facilities for multistep photolithography and vacuum-based *** simplify the fabrication of SAW microfluidic devices with customizable dimensions and functions,we utilized the additive manufacturing technique of aerosol jet *** successfully fabricated customized SAW microfluidic devices of varying materials,including silver nanowires,graphene,and poly(3,4-ethylenedioxythiophene)polystyrene sulfonate(PEDOT:PSS).To characterize and compare the acoustic actuation performance of these aerosol jet printed SAW microfluidic devices with their cleanroom-fabricated counterparts,the wave displacements and resonant frequencies of the different fabricated devices were directly measured through scanning laser Doppler ***,to exhibit the capability of the aerosol jet printed devices for lab-on-a-chip applications,we successfully conducted acoustic streaming and particle concentration ***,we demonstrated a novel solution-based,direct-write,single-step,cleanroom-free additive manufacturing technique to rapidly develop SAW microfluidic devices that shows viability for applications in the fields of biology,chemistry,engineering,and medicine.