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国外纺织技术（化纤．染整．环境保护分册） 1989年第6期 20-23页

作者： b.a.cameron M.T.Pailthorpe 袁农

引言目前,对于通常用于羊毛的各种染料的防染,还没有普遍有效的反应性防染处理方法。许多早期的羊毛防染处理都是基于破坏阳极“上染位置”和阴离子染料分子之间的离子引力而获得防染这一假设的。由于这一假设已被证实是不正确的。

关键词：氨基磺酸羊毛染色性能

Optimizing oncolytic virus design:a“Swiss army knife”approach to create a systemically delivered therapeutic

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Signal Transduction and Targeted Therapy 2024年第5期9卷 1791-1792页

作者： Carolina S.Ilkow John cameron bell Ottawa Hospital Research Institute 501 Smyth RoadOttawaONK1H 8L6Canada

In a recent paper published in Nature biotechnology,Chen et al.1 describe a multiplex oncolytic virus platform that coupled with adoptive T cell therapy could solve the problem of repeat,systemic delivery of virus based *** is widely accepted that multi-targeted therapeutic approaches attacking several facets of cancer biology are necessary to effectively deal with the tumor heterogeneity that exists within and between patients.

关键词： therapeutic al. targeted

An electropenetrography waveform library for the probing and ingestion behaviors of Culex tarsalis on human hands

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Insect Science 2024年第4期31卷 1165-1186页

作者： Anastasia M.W.Cooper Samuel b.Jameson Victoria Pickens cameron Osborne Elaine A.backus Kristopher Silver Dana N.Mitzel Department of Entomology Kansas State UniversityManhattanKansasUSA Department of Tropical Medicine Tulane University School of Public Health and Tropical MedicineNew OrleansLos AngelesUSA USDA Agricultural Research Service San Joaquin Valley Agricultural Sciences CenterParlierCaliforniaUSA National bio and Agro-Defense Facility USDA Agricultural Research ServiceManhattanKansasUSA

Culex tarsalis Coquillett(Diptera:Culicidae)mosquitoes are capable of vectoring numerous pathogens affecting public and animal ***,the probing behaviors of mosquitoes are poorly understood because they occur in opaque ***(EPG)has the potential to elucidate these behaviors by recording the electrical signals generated during *** used an AC–DC EPG with variable input resistors(Ri levels)to construct a waveform library for *** feeding on human *** events associated with mosquito probing were used to characterize waveforms at four Ri levels and with two electrical current *** optimal settings for EPG recordings of *** probing on human hands was an Ri level of 10^(7)Ohms using an applied signal of 150 millivolts alternating *** for *** included those previously observed and associated with probing behaviors in Aedes aegypti L.(Diptera:Culicidae):waveform families J(surface salivation),K(stylet penetration through the skin),L(types 1 and 2,search for a blood vessel/ingestion site),M(types 1 and 2,ingestion),N(type 1,an unknown behavior which may be a resting and digestion phase),and W(withdrawal).However,we also observed variations in the waveforms not described in ***,which we named types L3,M3,M4,and *** investigation enhances our understanding of mosquito probing *** also provides a new tool for the automated calculation of peak *** work will facilitate future pathogen acquisition and transmission studies and help identify new pest and disease management targets.

关键词： AC-DC blood feeders electrical penetration graph EPG human hands mosquitoes waveform library

Comparative utility of vestibular function tests in patients with peripheral and central vestibular dysfunction

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Journal of Otology 2024年第1期19卷 5-9页

作者： cameron b.Fattahi Christopher Zaro Janice J.Chung Richard F.Lewis Divya A.Chari Department of Otolaryngology-Head and Neck Surgery UMASS Memorial Medical CenterUniversity of Massachusetts Chan Medical SchoolWorcesterMAUSA Jenks Vestibular Physiology Laboratory Massachusetts Eye and EarBostonMAUSA Department of Otolaryngology-Head and Neck Surgery Massachusetts Eye and EarHarvard Medical SchoolBostonMAUSA Department of Neurology Harvard Medical SchoolBostonMAUSA

background: bithermal caloric irrigation, video head impulse test(vHIT), and rotational testing are commonly used to assess peripheral vestibular function, but the relative clinical utility of each test in differentiating patients with peripheral vestibulopathy is ***: To determine whether(1) the combination of two or more vestibular tests enhances diagnostic utility over a single test;(2) abnormal test results on vestibular tests correlate with one ***: Retrospective analysis of data collected from multidisciplinary vestibular clinics at two academic medical centers from 2016 to ***: 150 patients(54.10 ± 15.09 years, 88 females) were included. No individual test was significantly better at predicting the presence of peripheral vestibular damage(p > 0.05). vHIT test results improved significantly when combined with either the caloric test(p = 0.007) or rotary chair test(p = 0.039). Caloric and rotational testing had high sensitivity(74.65% and 76.06%, respectively) and specificity(83.54% and 78.48%, respectively). vHIT demonstrated excellent specificity(89.87%) but poor sensitivity(47.89%). Caloric, vHIT, and rotary chair tests results did not correlate with one another(p > 0.05).Conclusions: Vestibular function tests have comparable diagnostic utility, yet each offers unique advantages. Caloric and rotational testing may be best suited for screening peripheral damage and vHIT may function ideally as a confirmatory test.

关键词： vestibular patients specificity

清代文官的组织人口学研究(1830—1911)

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社会科学研究 2024年第1期 157-169,212页

作者：康文林高帅奇香港科技大学社会科学部中国香港999077 华中师范大学中国近代史研究所湖北武汉430079

中国历史官员量化数据库——(清)缙绅录(CGED-Q JSL)中文官的纵向关联记录揭示了19世纪清代文官整体的职业动态。定量分析的结果表明,清代官僚系统的总体情况就像一个当代的大型组织,文官离职率在任职的第一年内很高,然后下降,之后趋于... 详细信息

中国历史官员量化数据库——(清)缙绅录(CGED-Q JSL)中文官的纵向关联记录揭示了19世纪清代文官整体的职业动态。定量分析的结果表明,清代官僚系统的总体情况就像一个当代的大型组织,文官离职率在任职的第一年内很高,然后下降,之后趋于稳定。19世纪下半叶,官员的离职率整体下降,但于清末十年中上升。官员离职率下降导致拥有功名的候缺待补官员群体谋求仕途和进一步晋升的机会不断减少。同时,异途官员的人数不断增加,加剧了官场竞争。不同类别、品级官员的职业动态在不同历史时期的变化趋势差异较大,尤其是高品级官员的离职率对清代后期的官场平衡具有深刻影响。清代文官的职业动态一方面揭示了清代文官组织人口学的基本特征,另一方面也为解释清代特定官员群体或特定时期的官员个案研究提供了重要参考。

关键词：文官组织人口学《缙绅录》 CGED-Q JSL数据库

Dynamic material performance of cold-formed steel hollow sections： a state-of-the-art review

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Frontiers of Structural and Civil Engineering 2017年第2期11卷 209-227页

作者： cameron b. RITCHIE Jeffrey A. PACKER Xiao-Ling ZHAO Amin HEIDARPOUR Yiyi CHEN Department of Civil Engineering University of Toronto Toronto Ontario MSS 1A4 Canada Department of Civil Engineering Monash University Victoria 3800 Australia College of Civil Engineering Tongji University Shanghai 200092 China

This paper presents a literature review focused on the material performance of cold-formed, carbon steel, hollow structural sections under impulsive （highly dynamic） loading. Impulsive loading, represented by impact and blast, is characterized by a very rapid, time-dependent loading regime in the affected members and materials. Thus, the effect of high-strain-rate loading is initially reviewed. Next the material toughness, an important energy-absorption property and one measure of a material＇s ability to arrest fracture, is considered by means of studying the Charpy V-notch behavior. The response of hollow sections under axial and lateral impact loading is then reviewed. Studies of blast on hollow sections, most of which fall under the categories of contact/near-field loading or far-field loading are presented. Under large-scale field blast experiments, cold-formed hollow sections have shown excellent behavior. Software for modeling blast loading and structural response, the latter including single degree of freedom analysis and explicit finite element analysis, is described and discussed.

关键词： cold-formed steel hollow structural sections composites impulsive loading impact blast experimentation analysis material properties

A longitudinal analysis of the U.S. Air Force Reserve Officers’ Training Corps physical fitness assessment

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Military Medical Research 2020年第2期7卷 166-173页

作者： cameron SMackey Jason MDe Freitas Applied Neuromuscular Physiology Laboratory Oklahoma State University192 CRCStillwaterOK 74078USA

background:The *** Force physical fitness assessment(PFA)is used to determine the overall fitness of their *** is currently unknown to what extent the PFA scores of Reserve Officers’Training Corps(ROTC)cadets are affected by mandatory physical *** purpose of this investigation was to longitudinally examine the PFAs of ROTC cadets over a four-year period,evaluate the results across class ranks,and evaluate the sensitivity of the classification of the ***:Air Force ROTC cadets performed the PFAs(abdominal circumference,1-min pushups,1-min sit-ups,and a 1.5-mile run)in both the spring(n=26)and fall(n=22)*** were compiled over a four-year period(Spring 2014–Fall 2017)and were performed in accordance with Air Force Instruction 36–2905.A oneway repeated measures ANOVA was performed separately for the fall and spring groups for each dependent variable across the 4 ***,a one-way between groups ANOVA was performed for each dependent variable during the time point(fall 2015;n=46)with the most recorded cadets for each class ***:Longitudinal assessments revealed a main effect of time(P=0.010)on abdominal circumference;cadets had a smaller abdominal circumference in their freshman year than in their senior year.A main effect of time(P=0.006)was also observed on sit-up quantity;cadets performed more sit-ups in their junior year than in their freshman *** between class ranks during the same year(between-subjects ANOVA)revealed a main effect of class rank on sit-up quantity(P=0.003);the freshmen completed fewer repetitions than the sophomores(P=0.018)and the juniors did(P=0.001).Conclusions:The results indicated that only the sit-up component showed differences between class *** findings suggest that the Air Force PFA may not be sensitive enough to detect changes in physical fitness or distinguish between class ranks regarding physical performance,even after years of *** limitation may b

关键词： Class ranks Fitness assessment Military Physical training ROTC

Vitamin D receptor expression in human bone tissue and dose-dependent activation in resorbing osteoclasts

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bone Research 2016年第3期4卷 164-173页

作者： Allahdad Zarei Alireza Morovat Kassim Javaid cameron P brown botnar Research Centre Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Science University of Oxford Oxford UK Clinical biochemistry Oxford University Hospitals NHS Trust Oxford UK

The effects of vitamin D on osteoblast mineralization are well documented. Reports of the effects of vitamin D on osteoclasts, however, are conflicting, showing both inhibition and stimulation. Finding that resorbing osteoclasts in human bone express vitamin D receptor （VDR）, we examined their response to different concentrations of 25-hydroxy vitamin D3 [25（OH）D3] （100 or 500 nmol·L^-1） and 1,25-dihydroxy vitamin D3 [1,25（OH）2D3] （0.1 or 0.5 nmol·L^-1） metabolites in cell cultures. Specifically, CD14＋ monocytes were cultured in charcoal-stripped serum in the presence of receptor activator of nuclear factor kappa-b ligand （RANKL） and macrophage colony-stimulating factor （M-CSF）. Tartrate-resistant acid phosphatase （TRAP） histochemical staining assays and dentine resorption analysis were used to identify the size and number of osteoclast cells, number of nuclei per cell and resorption activity. The expression of VDR was detected in human bone tissue （ex vivo） by immunohistochemistry and in vitro cell cultures by western blotting. Quantitative reverse transcription-PCR （qRT-PCR） was used to determine the level of expression of vitamin D-related genes in response to vitamin D metabolites. VDR-related genes during osteoclastogenesis, shown by qRT-PCR, was stimulated in response to 500 nmol·L^-1 of 25（OH）D3 and 0.1-0.5 nmol·L^-1 of 1,25（OH）2D3, upregulating cytochrome P450 family 27 subfamily b member I （CYP27b1） and cytochrome P450 family 24 subfamily A member I （CYP24A1）. Osteoclast fusion transcripts transmembrane 7 subfamily member 4 （tm7sf4） and nuclear factor of activated T-cell cytoplasmic 1 （nfatcl） where downregulated in response to vitamin D metabolites. Osteoclast number and resorption activity were also increased. both 25（OH）D3 and 1,25（OH）2D3 reduced osteoclast size and number when co-treated with RANKL and M-CSF. The evidence for VDR expression in resorbing osteoclasts in vivo and low-dose effects of 1,25（OH）2D3 on osteoclasts in vitro may therefore provide

关键词： Vitamin D receptor expression in human bone tissue and dose-dependent activation in resorbing osteoclasts bone

Atomically dispersed dual-metal-site PGM-free electrocatalysts for oxygen reduction reaction:Opportunities and challenges

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SusMat 2022年第5期2卷 569-590页

作者： Xiaoxuan Yang cameron Priest Yang Hou Gang Wu College of Chemical and biological Engineering Zhejiang UniversityHangzhouChina Department of Chemical and biological Engineering University at BuffaloThe State University of New YorkBuffaloNew YorkUSA Institute of Zhejiang University-Quzhou QuzhouChina School of biological and Chemical Engineering NingboTech UniversityNingboChina

Atomically dispersed and nitrogen coordinated single metal site(MNx,M=Fe,Co,or Mn)moieties embedded in partially graphitized carbon(denoted as M–N–C)are recognized as the most promising platinum group metal-free catalysts for the oxygen reduction reaction(ORR)in proton exchange membrane fuel ***,simply regulating their coordination environments and local structures of single metal sites cannot fundamentally change active site structure,which leads to insufficient activity and stability.A second transition metal can be incorporated to design dual-metal sites,offering a new opportunity to modulate the electronic and geometric structures of M–N–C ***,exploring optimal atomically dispersed dual-metal-site is essential to designing new active sites with enhanced ORR activity,and stability,especially breaking the activity-stability *** review provides a comprehensive analysis of the advances in developing atomically dispersed dual-metal site catalysts for the ORR,including innovative synthesis methods,primary structural configurations,and the mechanisms to promote catalytic *** aim to elucidate the crucial structure–property correlation,emphasizing the inherent electronic and geometric effects of dual metal ***,we discuss the current challenges of dual-metal site catalysts concerning rational design,precise synthesis,and high-fidelity structural characterization.

关键词： dual metal sites electrocatalysis fuel cells oxygen reduction PGM-free catalyst

In vitro angiogenesis in response to biomaterial properties for bone tissue engineering:a review of the state of the art

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Regenerative biomaterials 2023年第1期10卷 744-783页

作者： Else Ellermann Nima Meyer Ruth E.cameron Serena M.best Department of Materials Science and Metallurgy University of CambridgeCambridge CB30FSUK

bone tissue engineering(bTE)aims to improve the healing of bone fractures using scaffolds that mimic the native extracellular *** successful bone regeneration,scaffolds should promote simultaneous bone tissue formation and blood vessel growth for nutrient and waste ***,a significant challenge in regenerative medicine remains the development of grafts that can be vascularized *** other things,optimization of physicochemical conditions of scaffolds is key to achieving appropriate angiogenesis in the period immediately following *** phosphates and collagen scaffolds are two of the most widely studied biomaterials for bTE,due to their close resemblance to inorganic and organic components of bone,respectively,and their bioactivity,tunable biodegradability and the ability to produce tailored *** various strategies exist to enhance vascularization of these scaffolds in vivo,further in vitro assessment is crucial to understand the relation between physicochemical properties of a biomaterial and its ability to induce *** mono-culture studies can provide evidence regarding cell-material interaction of a single cell type,a co-culture procedure is crucial for assessing the complex mechanisms involved in angiogenesis.A co-culture more closely resembles the natural tissue both physically and biologically by stimulating natural intercellular interactions and mimicking the organization of the in vivo ***,a co-culture is a complex system requiring optimization of various parameters including cell types,cell ratio,culture medium and seeding *** fundamental knowledge of the mechanism behind the bioactivity of biomaterials and understanding the contribution of surface and architectural features to the vascularization of scaffolds,and the biological response in general,can provide an invaluable basis for future optimization *** review gives an overview of the

关键词： angiogenesis collagen scaffolds hydroxyapatite co-culture architectural features physicochemical properties