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International Journal of minerals,metallurgy and materials 2019年第1期26卷 52-63页

作者： V.H.Vargas I.mejía V.H.Baltazar-Hernández C.maldonado metallurgy and materials Research Institute Universidad Michoacana de San Nicolás de Hidalgo Edificio "U" Ciudad Universitaria materials Science and Engineering Program Autonomous University of Zacatecas

Five advanced high-strength transformation-induced plasticity(TRIP) steels with different chemical compositions were studied to correlate the retained austenite and nonmetallic inclusion content with their physical properties and the characteristics of the resistance spot welding nuggets. Electrical and thermal properties and equilibrium phases of TRIP steels were predicted using the JmatPro? software. Retained austenite and nonmetallic inclusions were quantified by X-ray diffraction and saturation magnetization techniques. The nonmetallic inclusions were characterized by scanning electron microscopy. The results show that the contents of Si, C, Al, and mn in TRIP steels increase both the retained austenite and the nonmetallic inclusion contents. We found that nonmetallic inclusions affect the thermal and electrical properties of the TRIP steels and that the differences between these properties tend to result in different cooling rates during the welding process. The results are discussed in terms of the electrical and thermal properties determined from the chemical composition and their impact on the resistance spot welding nuggets.

关键词： transformation-induced plasticity steel retained austenite non-metallic inclusions magnetic saturation electrical properties thermal properties resistance spot welding nugget

multi-Sectoral Reflections and Efforts in Strengthening Partnerships to Reduce Disaster Risk in mexico:The First muSe-IDRim Conference

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International Journal of Disaster Risk Science 2020年第5期11卷 686-691页

作者： Irasema Alcantara-Ayala Daniel Rodriguez-Velazquez Ricardo J Garnica-Pena Alejandra maldonado-martinez Institute of Geography National Autonomous University of Mexico(UNAM)04510 Mexico CityMexico National School of Social Work.National Autonomous University of mexico(UNAm) 04510 Mexico CityMexico Disaster Risk Reduction Consultant 04700 Mexico CityMexico

Notwithstanding the high societal impact of disasters in mexico,there is a lack of integrated efforts to establish a sound policy for reducing disaster risk to counterbalance the existing concentrated endeavors in disaster *** the face of such segmentation,the science and technology community has advocated for a change of perspective,from civil protection to integrated disaster risk *** first multi-Sectoral Conference towards Integrated Disaster Risk management in mexico:Building a National Public Policy(muSe-IDRim Conference)was held in mexico City at National Autonomous University of mexico,21-24 October *** support of the implementation of the Sendai Framework for Disaster Risk Reduction 2015-2030,the conference aimed at enhancing the dialogue between the scienee and technology community,citizens,civil society organizations,private and public sectors,and the federtil,state,and municipal governments to foster the process of transforming the current National Civil Protection System into a national public policy oriented towards integrated disaster risk management(DRm).Barriers and challenges to the implementation of integrated DRm were *** of integrated DRm challenges current socioeconomic structures and encourages all releva nt stakeholders to think,decide,and act from a different perspective and within and across spatial,temporal,jurisdictional,and institutional *** disaster risk from an integrated approach,learning skills that authorities have not learned or used,and hence,strengthening disaster risk governance are prerequisites to effectively manage disaster risk.

关键词： Disaster risk reduction Integrated disaster risk management mexico Science-based policy making SINAPROC

How inflammation influences psychiatric disease

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World Journal of Psychiatry 2024年第3期14卷 342-349页

作者： Eduardo Ferat-Osorio JoséLuis maldonado-García Lenin Pavón División de Investigación Clínica de la Coordinación de Investigación en Salud Instituto Mexicano del Seguro SocialMexico City 06720Mexico Departamento de Bioquímica Facultad de MedicinaUniversidad Nacional Autónoma de MéxicoCoyoacán 04510Ciudad de MéxicoMexico Departamento de Inmunología Escuela Nacional de Ciencias BiológicasInstituto Politécnico NacionalMexico City 11340Mexico Laboratorio de Psicoinmunología Instituto Nacional de Psiquiatría Ramón de la Fuente MuñizMexico City 14370Mexico

Recent studies highlight the strong correlation between infectious diseases and the development of neuropsychiatric *** this editorial,we comment on the article“Anti-infective therapy durations predict psychological stress and laparoscopic surgery quality in pelvic abscess patients”by Zhang et al,published in the recent issue of the World Journal of Psychiatry 2023;13(11):*** discussion highlighted the potential consequences of anxiety,depression,and psychosis,which are all linked to bacterial,fungal,and viral infections,which are relevant to the impact of inflammation on the sequelae in mental health as those we are observing after the coronavirus disease 2019 *** focus specifically on the immune mechanisms triggered by inflammation,the primary contributor to psychiatric ***,pathophysiological mechanisms such as organ damage,post-injury inflammation,and infectioninduced endocrine alterations,including hypocortisolism or autoantibody formation,significantly contribute to the development of chronic low-grade inflammation,promoting the emergence or development of psychiatric alterations in susceptible *** inflammation can have long-term effects on patients,a multidisciplinary treatment plan can avoid complications and debilitating health issues,and it is crucial to recognize and address the mental health implications.

关键词： Inflammation infection Depression Pelvic inflammatory disease Psychiatric complication

Severe colitis associated with docetaxel use:A report of four cases

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World Journal of Gastrointestinal Oncology 2010年第10期2卷 390-394页

作者： andres F Carrion Peter J Hosein Eugene m Cooper Gilberto Lopes Liset Pelaez Caio m Rocha-Lima Department of medicine Division of GastroenterologyHematology/OncologyPathologyUniversity of Miami Miller School of Medicine Johns Hopkins Singapore International medical Center

Diarrhea is a common side effect of *** colitis is a well known complication of antibiotic treatment that can also be observed,albeit rarely,with certain chemotherapeutic *** present four cases of severe colitis in patients undergoing treatment with taxane-based chemotherapy for pancreatic,lung and breast *** of them had recently received *** patient presented with a bowel perforation and three had endoscopic findings of pseudomembranous *** of these three patients had negative stool toxin assays for Clostridium *** the patient presenting with perforation,an emergency left hemicolectomy was performed and the pathological findings in the colon were acute inflammation and ischemic necrosis;the other three patients were treated with oral vancomycin and/or oral or intravenous metronidazole leading to complete resolution of the *** from pseudomembranous colitis,we describe patients presenting with neutropenic enterocolitis as well as ischemic colitis after docetaxel *** cases provide some insight into the spectrum and varied clinical presentations of severe colitis associated with taxane-based chemotherapy.

关键词： Pseudomembranous colitis Chemotherapy Clostridium diffi cile Docetaxel

Enhancing the graphene photocurrent using surface plasmons and a p-n junction

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Light(Science & Applications) 2020年第1期9卷 793-802页

作者： Di Wang andres E.Llacsahuanga Allcca Ting-Fung Chung Alexander V.Kildishev Yong P.Chen Alexandra Boltasseva Vladimir m.Shalaev School of Electrical and Computer Engineering Purdue UniversityWest LafayetteIN 47907USA Birck Nanotechnology Center Purdue UniversityWest LafayetteIN 47907USA Department of Physics and Astronomy Purdue UniversityWest LafayetteIN 47907USA Purdue Quantum Science and Engineering Institute(PQSEI) Purdue UniversityWest LafayetteIN 47907USA

The recently proposed concept of graphene photodetectors offers remarkable properties such as unprecedented compactness,ultrabroadband detection,and an ultrafast response ***,owing to the low optical absorption of pristine monolayer graphene,the intrinsically low responsivity of graphene photodetectors significantly hinders the development of practical *** address this issue,numerous efforts have thus far been made to enhance the light–graphene interaction using plasmonic *** approaches,however,can be significantly advanced by leveraging the other critical aspect of graphene photoresponsivity enhancement-electrical junction *** has been reported that the dominant photocarrier generation mechanism in graphene is the photothermoelectric(PTE)***,the two energy conversion mechanisms involved in the graphene photodetection process are light-to-heat and heat-to-electricity *** this work,we propose a meticulously designed device architecture to simultaneously enhance the two conversion ***,a gap plasmon structure is used to absorb a major portion of the incident light to induce localized heating,and a pair of split gates is used to produce a p-n junction in graphene to augment the PTE current *** gap plasmon structure and the split gates are designed to share common key components so that the proposed device architecture concurrently realizes both optical and electrical *** experimentally demonstrate the dominance of the PTE effect in graphene photocurrent generation and observe a 25-fold increase in the generated photocurrent compared to the un-enhanced *** further photocurrent enhancement can be achieved by applying a DC bias,the proposed device concept shows vast potential for practical applications.

关键词： electrical plasmon hinder

Hepatic rupture secondary to HELLP syndrome: outcomes in three cases

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World Journal of Emergency medicine 2024年第1期15卷 56-58页

作者： Salvador Gomez-Carro Ruben R.Lozano-Salazar Kassandra Santos-Zaldívar Victor andres Villasuso-Alcocer Nina méndez-Domínguez O'Horan General Hospital Merida 97000Mexico Highly Specialized Hospital of the Yucatan Peninsula Merida 97134Mexico National Institute of Perinatology.mexico City 11000 Mexico

Hypertensive disorders of pregnancy,including chronic hypertension,gestational hypertension,and preeclampsia,are the most common complications in pregnant women,affecting approximately 15%of pregnancies.[1,2]Hemolysis,elevated liver enzymes,and low platelet count(HELLP syndrome)can occur in 0.2%-0.6%of all pregnancies,and 10%-15%of patients are diagnosed with preeclampsia.[3,4]Among its severe complications,liver hematoma is remarkable and may lead to liver *** identification of HELLP syndrome is crucial for proper therapeutic management and to avoid fatal outcomes[4,5]since when a hepatic hematoma occurs,the risk of rupture increases to 12%.[3,5]

关键词： rupture HELLP hypertension pregnancy

Role of platelets and breast cancer stem cells in metastasis

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World Journal of Stem Cells 2020年第11期12卷 1237-1254页

作者： Gretel mendoza-Almanza Luis Burciaga-Hernandez Vilma maldonado Jorge melendez-Zajgla Jorge Olmos CONACYT Universidad Autónoma de Zacatecas.Zacatecas 98060Mexico maestría en Ciencias Biomédicas Universidad Autónoma de ZacatecasZacatecas 98160Mexico Laboratorio de Epigenética Instituto Nacional de Medicina GenómicaCiudad de México 14610Mexico Génómica funcional del cáncer Instituto Nacional de Medicina GenómicaCiudad de México 14610Mexico Biotecnología marina Centro de Investigación Científica y de Estudios Superiores de EnsenadaEnsenada 22860Mexico

The high mortality rate of breast cancer is mainly caused by the metastatic ability of cancer cells,resistance to chemotherapy and radiotherapy,and tumor regression *** recent years,it has been shown that the presence of breast cancer stem cells is closely associated with the migration and metastatic ability of cancer cells,as well as with their resistance to chemotherapy and *** tumor microenvironment is one of the main molecular factors involved in cancer and metastatic processes development,in this sense it is interesting to study the role of platelets,one of the main communicator cells in the human body which are activated by the signals they receive from the microenvironment and can generate more than one *** can ingest and release RNA,proteins,cytokines and growth *** the platelets interact with the tumor microenvironment,they are called"tumor-educated platelets."Tumor-educated platelets transport material from the tumor microenvironment to sites adjacent to the tumor,thus helping to create microenvironments conducive for the development of primary and metastatic *** has been observed that the clone capable of carrying out the metastatic process is a cancer cell with stem cell *** stem cells go through a series of processes,including epithelial-mesenchymal transition,intravasation into blood vessels,movement through blood vessels,extravasation at the site of the establishment of a metastatic focus,and site ***-educated platelets support all these processes.

关键词： Breast cancer stem cells Platelets metastasis Tumor microenvironment Epithelial-mesenchymal transition

Zeolite-templated carbons as effective sorbents to remove methylsiloxanes and derivatives:A computational screening

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Green Energy & Environment 2021年第6期6卷 884-892页

作者： Shiru Lin Kaitlyn A.Jacoby Jinxing Gu Dariana R.Vega-Santander Arturo J.Hernaandez-maldonado Zhongfang Chen Department of Chemistry University of Puerto RicoRío PiedrasSan JuanPR 00931USA Department of Chemistry&Biochemistry Elizabethtown CollegeElizabethtownPA 17022USA Department of Chemical Engineering University of Puerto RicoMayaguez CampusMayaguezPR 00681USA

Though widely used in our daily lives,volatile methylsiloxanes and derivatives are emerging contaminants and becoming a high-priority environment and public health *** effective sorbent materials can remove siloxanes in a cost-effective ***,by means of Grand Canonical monte Carlo(GCmC)simulations,we evaluated the potentials of the recently proposed 68 stable zeolite-templated carbons(ZTCs)(PNAS 2018,115,E8116-E8124)for the removal of four linear methylsiloxanes and derivatives as well as two cyclic methylsiloxanes by the calculated average loading and average adsorption energy *** ZTCs,namely ISV,FAU1,FAU3,and H8326836,were identified with the top 50%adsorption performance toward all the six targeted contaminants,which outperform activated *** first principles computations revealed that steric hindrance,electrostatic interactions(further enhanced by charge transfer),and CH-p interactions account for the outstanding adsorption performance of these *** work provides a quick procedure to computationally screen promising ZTCs for siloxane removal,and help guide future experimental and theoretical investigations.

关键词： Zeolite-templated carbons Contaminants of emerging concern methylsiloxanes GCmC simulations Density functional theory calculations

Gastric infiltration of diffuse large B-cell lymphoma: Endoscopic diagnosis and improvement of lesions after chemotherapy

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World Journal of Gastroenterology 2008年第27期14卷 4407-4409页

作者： Sergio Zepeda-Gómez Jesús Camacho Edgar Oviedo-Cárdenas Carmen Lome-maldonado Department of Gastrointestinal Endoscopy Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán" Department of Pathology Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán"

Diffuse large B-cell lymphoma (DLBCL) is the most common histologic subtype of the non-Hodgkin’s lymphoma (NHL) accounting for about 40% of all NHLs. This is a case report about the endoscopic appearance of a DLBCL with infiltration to the stomach in a 39-year-old female. She had a 6-mo history of lumbar and left upper quadrant pain with intermittent episodes of melena. A computer tomograghy (CT) scan showed mural thickening of the gastric antrum. Endoscopic examination revealed multiple gastric ulcers. Definite diagnosis could be made by endoscopic biopsies and the patient had a good response to chemotherapy. This response correlated well with a further endoscopic follow-up. A follow-up endoscopic examination could be considered to evaluate a good response to chemotherapy in DLBCL patients with secondary gastric dissemination.

关键词： Diffuse large B-cell lymphoma Non-Hodgkin's lymphoma Gastric infiltration

Correlation between metabolic syndrome and sleep apnea

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World Journal of Diabetes 2018年第4期9卷 66-71页

作者： Alejandro Castaneda Edgar Jauregui-maldonado Iqbal Ratnani Joseph Varon Salim Surani Dorrington medical Associates HoustonTX 77030United States DeBakey Heart and Vascular Center Houston MethodistHoustonTX 77030United States Department of Acute and Continuing Care.The University of Texas Health Science Center Houston TX 77030United States Division of Pulmonary Critical Care and Sleep MedicineTexas A and M UniversityHealth Science CenterCorpus ChristiTX 78404United States

The so-called "metabolic syndrome"(mS),constitutes a cluster of metabolic and cardiovascular abnormalities,including fasting glucose,blood pressure,triglycerides,high density lipoprotein cholesterol(HDL-C),and waist circumference that arise from insulin resistance. Obstructive sleep apnea(OSA) syndrome is characterized by recurrent episodes of partial or complete obstruction of the upper airway,involving cessation or significant decreased airflow,with intermittent hypoxemia,frequent arousals from sleep and recurrent oxyhemoglobin desaturations that interfere with normal sleep patterns generating difficulty falling asleep,unrefreshing sleep and loud snoring. The relation between these two entities is known as "Syndrome Z",and there is no question about the impact of these risk factors on health and disease. This clinical condition presents a growing epidemic Worldwide,affecting approximately 60% of the general population with both mS and OSA due to the constant increase of body mass index in humans. This article presents evidence-based data that focuses on the direct relationship between mS and OSA.

关键词： Obstructive sleep apnea metabolic syndrome Sleep apnea Obesity Syndrome Z