检索结果-南通市图书馆

Chinese Chemical Letters 2024年第3期35卷 443-448页

作者： Linhe Xu Xueshan Hu Shuang Zhou Ze Zhang Junxian Zhang Chao Li Daxian zuo Hao Liu Gang chen Jiayu Wan Jinsong Tao State Key Lab of Pulp and Paper Engineering South China University of TechnologyGuangzhou 510640China Future Battery Research Center Global Institute of Future TechnologyShanghai Jiao Tong UniversityShanghai 200240China

Accurate detection of uric acid(UA)is crucial for diagnosing gout,yet traditional sweat-based UA sensors continue to face challenges posed by complex and costly electrode fabrication methods,as well as weakly hydrophilic ***,we designed and developed simple,low-cost,and hydrophilic sweat UA detection sensors constructed by carbon electrodes and cellulose paper *** carbon electrodes were made by carbonized polyimide films through a simple,one-step laser engraving *** electrodes are porous,possess a large specific surface area,and are flexible and *** substrates were composed of highly hydrophilic cellulose paper that can effectively collect,store,and transport *** constructed electrodes demonstrate high sensitivity of 0.4μA Lμmol^(-1)cm^(-2),wide linear range of 2–100μmol/*** addition,our electrodes demonstrate high selectivity,excellent reproducibility,high flexibility,and outstanding stability against mechanical bending,temperature variations,and extended storage ***,our sensors have been proven to provide reliable results when detecting UA levels in real sweat and on real human *** envision that these sensors hold enormous potential for use in the prognosis,diagnosis,and treatment of gout.

关键词： Laser-engraved carbon Polyimide Cellulose paper Hydrophilicity Sweat uric acid

Comprehensive understanding on sources of high levels of fine particulate nitro-aromatic compounds at a coastal rural area in northern China

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第1期135卷 483-494页

作者： Yueru Jiang Xinfeng Wang Min Li Yiheng Liang Zhiyi Liu Jing chen Tianyi guan Jiangshan Mu Yujiao Zhu He Meng Yang Zhou Lan Yao Likun Xue Wenxing Wang Environment Research Institute Shandong UniversityQingdao 266237China Department of Environmental Systems Science Swiss Federal Institute of Technology ZurichZurich 8092Switzerland Department of Water Resources and Drinking Water Swiss Federal Institute of Aquatic Science and TechnologyDuebendorf 8600Switzerland Qingdao Eco-Environment Monitoring Center of Shandong Province Qingdao 266003China College of Oceanic and Atmospheric Sciences Ocean University of ChinaQingdao 266100China School of Environmental and Geographical Sciences Shanghai Normal UniversityShanghai 200234China

Nitro-aromatic compounds(NACs)are among the major components of brown carbon(BrC)in the atmosphere,causing negative impacts on regional climate,air quality,and ecological *** to the extensive origins,it is still a challenge to figure out the contributions and originating regions for different sources of atmospheric ***,field observations on fine particulate NACs were conducted at a coastal rural area in Qingdao,China in the winter of 2018 and *** mean total concentrations of fine particulate nitro-aromatic compounds were 125.0±89.5 and 27.7±21.1 ng/m^(3)in the winter of 2018 and 2019,*** the measured eleven NACs,nitrophenols and nitrocatechols were the most abundant *** characteristics and correlation analysis showed that humidity and anthropogenic primary emissions had significant influences on the NAC *** this study,two tracing methods of the improved spatial concentration weighted trajectory(SCWT)model and the receptor model of positive matrix factorization(PMF)were combined to comprehensively understand the origins of NACs in fine particles at coastal *** major sources were identified,including coal combustion,biomass burning,vehicle exhaust,and secondary ***,coal combustion was responsible for about half of the observed nitro-aromatic compounds,followed by biomass burning(~30%).The results by SCWT demonstrated that the coal combustion dominated NACs mainly originated from the Shandong peninsula and the areas to the north and southwest,while those dominated by biomass burning primarily came from local Qingdao and the areas to the west.

关键词： Nitro-aromatic compounds Fine particles Source apportionment Originating region Combustion activities

Highly efficient room temperature phosphorescent liquid crystalline polymer optical waveguides for advanced optoelectronics

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2024年

作者： Jie Li Yan guan Wei Xia Jin-Kang chen Jiang Huang Yi chen Qi Lin Er-Qiang chen He-Lou Xie Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education and Key Laboratory of Advanced Functional Polymer Materials of CollegesUniversities of Hunan Province and College of ChemistryXiangtan University Beijing National Laboratory for Molecular Sciences Key Laboratory of Polymer Chemistry and Physics of Ministry of EducationCollege of Chemistry and Molecular EngineeringPeking University School of Physics and Optoelectronics Xiangtan University

Active organic optical waveguide materials (OOWMs) incorporating room temperature phosphorescence (RTP) hold significant promise for diverse applications in photonic and optoelectronic *** this potential,realizing active RTP optical waveguides with large-sized ordered structures and minimal light loss remains a formidable *** address this issue,we present a groundbreaking thermoplastic active OOWM with low light loss,leveraging room temperature phosphorescent liquid crystalline polymer (LCP).This innovative material can be easily synthesized through the copolymerization of phosphorescent and liquid crystalline *** resulting RTP copolymer exhibits a nematic liquid crystal phase with a phosphorescence lifetime of approximately 0.15 ms and an afterglow duration of around 1 *** the excellent processability of LCP,we successfully produce meter-scale fibers via melt *** RTP LCP fibers,characterized by a high orientation of mesogens along the fiber axis,demonstrate superior light confinement and efficient light conduction compared to unoriented samples,resulting in a low optical loss coefficient of 0.13 dB/***,the thermal responsiveness of the RTP LCP optical waveguide enables its use as a photo *** pioneering work paves the way for the design of new OOWMs tailored for advanced photonics and optoelectronics devices.

关键词：

Clinical practice guideline for acupuncture and moxibustion:Allergic rhinitis

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2024年第3期22卷 245-257页

作者： Shi-hao Du Sheng chen Shan-ze Wang guan-qun Wang Shuo Du Wei Guo Xiao-long Xie Bi-hui Peng Chao Yang Ji-ping Zhao Institute of Acupuncture and Moxibustion China Academy of Chinese Medical SciencesBeijing 100700China Department of Acupuncture and Moxibustion Dongzhimen HospitalBeijing University of Chinese MedicineBeijing 100700China Department of Acupuncture and Moxibustion Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Department of Traditional Chinese Medicine Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China

Acupuncture is one of the most effective complementary therapies for allergic rhinitis(AR)and has been recommended by several clinical practice guidelines(CPGs)for ***,these CPGs mentioned acupuncture without making recommendations for clinical implementation and therapeutic protocols,therefore limiting the applicability of acupuncture therapies for ***,for the benefit of acupuncture practitioners around the world,the World Federation of Acupuncture-moxibustion Societies have initiated a project to develop the CPG for the use of acupuncture and moxibustion to treat *** CPG was developed according to the Grading of Recommendations Assessment,Development,and Evaluation(GRADE)methodology,referring to the principles of the World Health Organization Handbook for Guideline *** the development of the CPG,the guideline development group(GDG)played an important *** clinical questions,recommendations and therapeutic protocols were all formulated by the GDG using the modified Delphi *** CPG contains recommendations for 15 clinical questions about the use of acupuncture and moxibustion *** include one strong recommendation for the intervention based on high-quality evidence,three conditional recommendations for either the intervention or standard care,and 11 conditional recommendations for the intervention based on very low quality of *** CPG also provides one filiform needle acupuncture protocol and five moxibustion protocols extracted based on the protocols presented in randomized controlled trials reviewed by the GDG.

关键词： Clinical practice guideline Allergic rhinitis Acupuncture Moxibustion GRADE

Clinical practice guideline for acupuncture and moxibustion: Female urinary incontinence

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2024年第3期22卷 258-269页

作者： Chao Yang Shan-ze Wang Sheng chen Shuo Du guan-qun Wang Wei Guo Xiao-long Xie Bi-hui Peng Shi-hao Du Ji-ping Zhao Department of Acupuncture and Moxibustion Dongzhimen HospitalBeijing University of Chinese MedicineBeijing 100700China Department of Acupuncture and Moxibustion Guangdong provincial hospital of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Shanghai Ninth People’s Hospital Shanghai Jiao Tong University School of MedicineShanghai 200011China Institute of Acupuncture and Moxibustion China Academy of Chinese Medical SciencesBeijing 100700China

Urinary incontinence (UI) is a common problem *** has a major impact on physical and social activities and interpersonal *** is common in women,but is under-reported and *** affects the quality of life of female patients *** and moxibustion have been proposed as potentially effective interventions for female ***,for the benefit of acupuncture practitioners around the world,the World Federation of Acupuncture-moxibustion Societies initiated a project to develop a clinical practice guideline (CPG) for the use of acupuncture and moxibustion to treat female *** CPG was developed according to the Grading of Recommendations Assessment,Development,and Evaluation (GRADE) methodology,referring to the principles of the World Health Organization Handbook for Guideline *** the development of the CPG,the guideline development group (GDG) played an important *** clinical questions,recommendations and therapeutic protocols were all formulated by GDG using the modified Delphi *** CPG contains ten recommendations about the use of acupuncture and moxibustion interventions for ten clinical questions,which include nine conditional recommendations for the intervention and one conditional recommendation for either the intervention or the *** CPG also provides one protocol for conventional filiform needle therapy,two therapy protocols for deep needling stimulation on lumbosacral acupoints,and four moxibustion therapy protocols,based on the protocols presented in randomized controlled trials reviewed by the GDG.

关键词： Acupuncture Clinical practice guideline Female urinary incontinence Moxibustion GRADE

Updated prevalence of latent prostate cancer in Chinese population and comparison of biopsy results: An autopsy-based study

在线全文

学校读者我要写书评

暂无评论

The Innovation 2024年第1期5卷 80-87页

作者： Yuliang chen Zhien Zhou Yi Zhou Zhipeng Mai Shijie Jin Zhen Liang Zhiyuan Shang Yuzhi zuo Yu Xiao Wenze Wang Haibo Wang Weigang Yan Department of Urology Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100730China Department of Gynaecology and Obstetrics Beijing HospitalNational Centre of GerontologyBeijing 100730China Department of Pathology Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100730China Peking University Clinical Research Institute Peking University First HospitalBeijing 100034China

Prostate cancer detected by autopsy is named latent prostate *** the repertoire of clinical prostate cancer,latent cancer may better reflect the disease *** clinical prostate specimens,which are obtained exclusively from biopsy-positive cases,prostate specimens obtained through autopsy provide information on biopsy-negative cases,helping calculate the true sensitivity of prostate *** 2014 to 2021,we collected autopsy specimens of the prostate from body donors in China and performed transperineal and transrectal biopsies on specimens before step-sectioning and pathological *** found that the crude prevalence of latent prostate cancer in middle-aged and elderly men was 35.1%(81/231),which was higher than previous estimates for Chinese *** overall per-patient sensitivities of transperineal and transrectal biopsies were not significantly different(33.3%vs.32.1%,p=0.82),but the two approaches differed in preferential sampling area along the proximal-distal axis of the *** biopsy had a higher sensitivity for detecting clinically significant lesions in the distal third(34.7%vs.16.3%,p=0.02)and distal half(30.6%vs.18.1%,p=0.04),while transrectal biopsy had a higher sensitivity for lesions in the proximal half(25.0%vs.13.9%,p=0.046).Both transperineal and transrectal methods of biopsy missed most small lesions(0.5 mL).In conclusion,the prevalence of latent prostate cancer in China has increased over the past 2 *** transperineal and transrectal methods of biopsy had comparable sensitivities but had different preferential sampling *** approaches miss one-third of large lesions.

关键词： biopsy prevalence latent

Relationship between plasma risperidone concentrations and clinical features in chronic schizophrenic patients in China

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2024年第4期14卷 523-532页

作者： Jing-Wen Xu Xiao-Bo guan Xue-Ying Wang Yang Feng Qi Zhang Jun-Juan Zhu Jian-Hua chen Department of Medicine Shanghai No.3 Mental Health Center of Civil AdministrationShanghai 200435China The Fourth Sick Ward Shanghai No.3 Mental Health Center of Civil AdministrationShanghai 200435China Shanghai Mental Health Center Shanghai Jiao Tong University School of MedicineShanghai Key Laboratory of Psychotic DisordersShanghai 200030China The First Sick Ward Shanghai No.3 Mental Health Center of Civil AdministrationShanghai 200435China

BACKGROUND Prior studies have noted great variability in the plasma levels of risperidone(RIS).Plasma concentrations of RIS and its active moiety are highly variable and depend on absorption,metabolism,and other predictors of metabolic dysregulation;however,these factors are poorly understood and the association between metabolic change and change in psychopathology is *** To ascertain the characteristics of chronic schizophrenic patients treated with RIS,and to assess their relationship with plasma RIS *** This was a descriptive cross-sectional study of 50 patients with a diagnosis of schizophrenic psychosis treated with RIS in a psychiatric *** plasma concentrations of RIS and its metabolite 9-hydroxyrisperidone were determined by high performance liquid *** patients’demographic and clinical characteristics,and psychopathologies were assessed,and the associations between clinical variables and plasma levels of RIS were *** Male patients received higher doses of RIS than female ones,but plasma concentrations of RIS and risperidone+9-hydroxyrisperidone(active moiety)were higher in female *** and the mean scores of the general psychopathology subscale of the Positive and Negative Syndrome Scale(PANSS)were significantly positively correlated with plasma concentrations of risperidone+9-hydroxyrisperidone adjusted for weight and dose in all 50 *** male subjects,we found a statistically significant positive correlation between the concentrations of risperidone+9-hydroxyrisperidone in plasma/(dose×kg)and age,mean PANSS negative subscale scores,mean PANSS general psychopathology subscale scores,and mean PANSS total *** Long-term use of RIS should be closely monitored in older patients and females to minimize the risk of high concentrations which could induce side effects.

关键词： Antipsychotics Risperidone 9-hydroxyrisperidone Plasma drug concentration monitoring Chronic schizophrenia

Application of Regularization Methods in the Sky Map Reconstruction of the Tianlai Cylinder Pathfinder Array

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第2期24卷 24-35页

作者： Kaifeng Yu Shifan zuo Fengquan Wu Yougang Wang Xuelei chen National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Key Laboratory of Radio Astronomy and Technology Chinese Academy of SciencesBeijing 100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China Key Laboratory of Cosmology and Astrophysics(Liaoning)&College of Sciences Northeastern UniversityShenyang 110819China Center of High Energy Physics Peking UniversityBeijing 100871China

The Tianlai cylinder pathfinder is a radio interferometer array to test 21 cm intensity mapping techniques in the post-reionization *** works in passive drift scan mode to survey the sky visible in the northern *** deal with the large instantaneous field of view and the spherical sky,we decompose the drift scan data into m-modes,which are linearly related to the sky *** sky map is reconstructed by solving the linear interferometer *** to incomplete uv coverage of the interferometer baselines,this inverse problem is usually ill-posed,and regularization method is needed for its *** this paper,we use simulation to investigate two frequently used regularization methods,the Truncated Singular Value Decomposition(TSVD),and the Tikhonov regularization *** the regularization parameter is very important for its *** employ the generalized cross validation method and the L-curve method to determine the optimal *** compare the resulting maps obtained with the different regularization methods,and for the different parameters derived using the different *** both methods can yield good maps for a range of regularization parameters,in the Tikhonov method the suppression of noisy modes are more gradually applied,produce more smooth maps which avoids some visual artefacts in the maps generated with the TSVD method.

关键词： techniques interferometric-methods numerical-cosmology observations-radio continuum general

Immunoglobulin G-mediated food intolerance and metabolic syndrome influence the occurrence of reflux esophagitis in Helicobacter pylori-infected patients

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第8期30卷 855-862页

作者： Li-Hui Wang Bin-Bin Su Sheng-Shu Wang guan-Chao Sun Kun-Ming Lv Yi Li Hui Shi Qian-Qian chen College Chinese PLA General HospitalBeijing 100853China Department of Gastroenterology Second Medical Center of Chinese PLA General HospitalBeijing 100853China Institute of Geriatrics The 2nd Medical CenterBeijing Key Laboratory of Aging and GeriatricsNational Clinical Research Center for Geriatrics DiseasesSecond Medical Center of Chinese PLA General HospitalBeijing 100853China Department of Gastroenterology First Medical Center of Chinese PLA General HospitalBeijing 100853China

BACKGROUND Reflux esophagitis has an increasing prevalence and complex and diverse *** its risk factors is crucial to understanding the etiology,prevention,and management of the *** occurrence of reflux esophagitis may be associated with food reactions,Helicobacter pylori(***)infection,and metabolic *** To investigate the risk factors for reflux esophagitis and analyze the effects of immunoglobulin(Ig)G-mediated food intolerance,*** infection,and metabolic syndrome on reflux *** Outpatients attending the Second Medical Center of the PLA General Hospital between 2017 and 2021 were retrospectively *** patients’basic information,test results,gastroscopy results,*** test results,and IgG-mediated food intolerance results were *** logistic regression analysis was used to analyze risk factors for reflux *** mediation analysis was used to evaluate the effects of IgG-mediated food intolerance and metabolic syndrome on *** infection affecting reflux *** A total of 7954 outpatients were included;the prevalence of reflux esophagitis,IgG-mediated food intolerance,*** infection,and metabolic syndrome were 20.84%,61.77%,35.91%,and 60.15%,*** analysis showed that the independent risk factors for reflux esophagitis included IgG-mediated food intolerance(OR=1.688,95%CI:1.497-1.903,P<0.00001)and metabolic syndrome(OR=1.165,95%CI:1.030-1.317,P=0.01484),and the independent protective factor for reflux esophagitis was *** infection(OR=0.400,95%CI:0.351-0.456,P<0.00001).IgG-mediated food intolerance had a partially positive mediating effect on *** infection as it was associated with reduced occurrence of reflux esophagitis(P=0.0200).Metabolic syndrome had a partially negative mediating effect on *** infection and reduced the occurrence of reflux esophagitis(P=0.0220).CONCLUSION Patients with IgG-mediated food intol

关键词： Gastroesophageal reflux Esophagitis Food intolerance Metabolic syndrome Helicobacter pylori Chemokines

The expression mechanism of programmed cell death 1 ligand 1 and its role in immunomodulatory ability of mesenchymal stem cells

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Traumatology 2024年第1期27卷 1-10页

作者： Zhuo chen Meng-Wei Yao Xiang Ao Qing-Jia Gong Yi Yang Jin-Xia Liu Qi-Zhou Lian Xiang Xu Ling-Jing zuo Department of Stem Cell&Regenerative Medicine State Key Laboratory of TraumaBurn and Combined InjuryDaping HospitalArmy Medical UniversityChongqing400042China College of Basic Medical Sciences Army Medical UniversityChongqing400038China Department of Orthopedics 953 Hospital of PLAShigatse Branch of Xinqiao HospitalArmy Medical UniversityShigatse857000Tibet Autonomous RegionChina Department of Rheumatology and Immunology Daping HospitalArmy Medical UniversityChongqing400042China Department of Obstetrics and Gynecology Chongqing People's HospitalChongqing401121China Department of Medicine Li Ka Shing Faculty of MedicineThe University of Hong KongHong KongChina Department of Nuclear Medicine The First People's Hospital of Yunnan provinceAffiliated Hospital of Kunming University of Science and TechnologyKunming650034China

Programmed cell death 1 ligand 1(PD-L1)is an important immunosuppressive molecule,which inhibits the function of T cells and other immune cells by binding to the receptor programmed cell *** PD-L1 expression disorder plays an important role in the occurrence,development,and treatment of sepsis or other inflammatory diseases,and has become an important target for the treatment of these *** stem cells(MSCs)are a kind of pluripotent stem cells with multiple differentiation *** recent years,MSCs have been found to have a strong immunosuppressive ability and are used to treat various inflammatory insults caused by hyperimmune ***,PD-L1 is deeply involved in the immunosuppressive events of MSCs and plays an important role in the treatment of various *** this review,we will summarize the main regulatory mechanism of PD-L1 expression,and discuss various biological functions of PD-L1 in the immune regulation of MSCs.

关键词： PD-L1 MSCs Immunomodulation