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BreedingAIDB: A database integrating crop genome-to-phenotype paired data with machine learning tools applicable to breeding

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Plant Communications 2024年第7期5卷 12-15页

作者： zijie Shen Enhui Shen Kun Yang Zuoqian Fan Qian-Hao Zhu Longjiang Fan Chu-yu Ye Hainan Institute Zhejiang UniversitySanya 572025China Institute of Crop Science&Institute of Bioinformatics College of Agriculture&BiotechnologyZhejiang UniversityHangzhou 310058China CSIRO Agriculture and Food CanberraACT 2601Australia

Machine learning(ML)is one of the key technologies for next-generation breeding,and“big data”is the cornerstone for development of ML algorithms that are applicable to crop breeding ***,there is a shortage of databases containing phenotype data and corresponding genomic data,i.e.,genome-to-phenotype(G2P)paired data,that can be used in the development of ML algorithms for *** fill this gap,we constructed a user-friendly database named the BreedingAIDB(http://***/BreedingAIDB)to provide breeders and ML experts with easily accessible G2P paired data for crops,as well as ML tools.

关键词： database learning breeding

Self-Assembly 3D Porous Crumpled MXene Spheres as Efficient Gas and Pressure Sensing Material for Transient All-MXene Sensors

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Nano-Micro Letters 2022年第4期14卷 1-14页

作者： zijie Yang Siyuan Lv yueying Zhang Jing Wang Li Jiang Xiaoteng Jia Chenguang Wang Xu Yan Peng Sun yu Duan Fangmeng Liu Geyu Lu State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin University2699 Qianjin StreetChangchun 130012People’s Republic of China School of Electronic and Information Engineering Changchun University of Science and TechnologyChangchun 130022People’s Republic of China

Environmentally friendly degradable sensors with both hazardous gases and pressure efficient sensing capabilities are highly desired for various promising applications,including environmental pollution monitoring/prevention,wisdom medical,wearable smart devices,and artificial ***,the transient gas and pressure sensors based on only identical sensing material that concurrently meets the above detection needs have not been ***,we present transient all-MXene NO_(2) and pressure sensors employing three-dimensional porous crumpled MXene spheres prepared by ultrasonic spray pyrolysis technology as the sensing layer,accompanied with water-soluble polyvinyl alcohol substrates embedded with patterned MXene *** gas sensor achieves a ppb-level of highly selective NO_(2) sensing,with a response of up to 12.11%at 5 ppm NO_(2) and a detection range of 50 ppb-5 ppm,while the pressure sensor has an extremely wide linear pressure detection range of 0.14-22.22 kPa and fast response time of 34 *** parallel,all-MXene NO_(2) and pressure sensors can be rapidly degraded in medical H_(2)O_(2) within 6 *** work provides a new avenue toward environmental monitoring,human physiological signal monitoring,and recyclable transient electronics.

关键词： All-MXene 3D porous crumpled MXene sphere Transient NO2 and pressure sensor

Engineering Shewanella-re duce d graphene oxide aerogel biohybrid to efficiently synthesize Au nanoparticles

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Journal of Materials Science & Technology 2024年第1期168卷 50-61页

作者： Baocai Zhang Shulin Shao Huan yu Qijing Liu Sicheng Shi Qingyuan Wu zijie Wu Yiyu Feng Yifei Wang Xi Sun Deguang Wu Feng Li Hao Song Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering(Ministry of Education) Tianjin UniversityTianjin 300072China Collaborative Innovation Center of Chemical Science and Engineering(Tianjin) School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300072China Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical TechnologyBeijing 100029China School of Materials Science and Engineering Tianjin UniversityTianjin 300350China College of Biological Engineering Tianjin Agricultural UniversityTianjin 300384China Department of Brewing Engineering Moutai InstituteLuban AveRenhuai 564507China

Biosynthesizing Au nanoparticles(AuNPs)from gold-bearing scraps provides a sustainable method to meet the urgent demand for ***,it remains challenging to efficiently biosynthesize AuNPs of which the diameter is less than 10 nm from a trace amount of Au^(3+)concentration at the level of tens ***,we constructed an exoelectrogenic cell(eCell)-conductive reduced-graphene-oxide aero-gel(rGA)biohybrid by assembling Shewanella sp.S1(SS1)as living biocatalyst and rGA as conductive ad-sorbent,in which Au^(3+)at trace concentrations would be enriched by the adsorption of rGA and reduced to AuNPs through the extracellular electron transfer(EET)of *** regulate the size of the synthe-sized AuNPs to 10 nm,the strain SS1 was engineered to enhance its EET,resulting in strain RS2(pYYD-P tac-ribADEHC&pHG13-P_(bad)-omcC in SS1).Strain RS2 was further assembled with rGA to construct the RS2-rGA biohybrid,which could synthesize AuNPs with the size of 7.62±2.82 nm from 60 ppm Au^(3+)*** eCell-rGA biohybrid integrated Au^(3+)adsorption and reduction,which enabled AuNPs biosyn-thesis from a trace amount of Au^(3+).Thus,the required Au^(3+)ions concentration was reduced by one or two orders of magnitude compared with conventional methods of AuNPs *** work devel-oped an AuNPs size regulation technology via engineering eCell’s EET with synthetic biology methods,providing a feasible approach to synthesize AuNPs with controllable size from trace level of gold ions.

关键词： Au nanoparticles Exoelectrogenic cell(e-Cell) Shewanella Synthesis biology Extracellular electron transfer Reduced graphene oxide aerogel

Three-Dimensional N-Doped Carbon Nanotube/Graphene Composite Aerogel Anode to Develop High-Power Microbial Fuel Cell

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Energy & Environmental Materials 2023年第3期6卷 161-169页

作者： Shixuan Jin Yiyu Feng Jichao Jia Fulai Zhao zijie Wu Peng Long Feng Li Huitao yu Chi Yang Qijing Liu Baocai Zhang Hao Song Wei Feng School of Material Science and Engineering Tianjin UniversityTianjin 300350China School of Chemical Engineering and Technology Tianjin UniversityTianjin 300350China

Optimizing the structure of electrode materials is one of the most effective strategies for designing high-power microbial fuel cells(MFCs).However,electrode materials currently suffer from a series of shortcomings that limit the output of MFCs,such as high intrinsic resistance,poor electrolyte wettability,and low microbial load ***,a three-dimensional(3D)nitrogen-doped multiwalled carbon nanotube/graphene(N-MWCNT/GA)composite aerogel is synthesized as the anode for *** nitrogen-doped GA,MWCNT/GA,and N-MWCNT/GA,the macroporous hydrophilic N-MWCNT/GA electrode with an average pore size of 4.24μm enables high-density loading of the microbes and facilitates extracellular electron transfer with low intrinsic ***,the hydrophilic surface of N-MWCNT can generate high charge mobility,enabling a high-power output performance of the *** consequence,the MFC system based on N-MWCNT/GA anode exhibits a peak power density and output voltage of 2977.8 mW m^(−2)and 0.654 V,which are 1.83 times and 16.3%higher than those obtained with MWCNT/GA,*** results demonstrate that 3D N-MWCNT/GA anodes can be developed for high-power MFCs in different environments by optimizing their chemical and microstructures.

关键词： anode graphene aerogel microbial fuel cell N-doped carbon nanotube

Tomography of emissivity for Doppler coherence imaging spectroscopy diagnostic in HL-2A

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Plasma Science and Technology 2021年第9期23卷 34-48页

作者： Bingli LI Tianbo WANG Lin NIE Ting LONG zijie LIU Hao WU Rui KE Zhanhui WANG Yi yu Min XU Southwestern Institute of Physics Chengdu 610041People's Republic of China University of Science and Technology of China Hefei 230026People's Republic of China Department of Applied Physics Ghent University9000 Ghent.Belgium

A newly developed Doppler coherence imaging spectroscopy(CIS)technique has been implemented in the HL-2 A tokamak for carbon impurity emissivity and flow *** CIS diagnostics,the emissivity and flow profiles inside the plasma are measured by a camera from the line-integrated emissivity and line-averaged flow,respectively.A standard inference method,called tomographic inversion,is *** an inversion is relatively challenging due to the ill-conditioned *** this article,we report the recent application and comparison of two different tomography algorithms,Gaussian process tomography and Tikhonov tomography,on light intensity measured by CIS,including feasibility and benchmark ***,the tomographic results for real measurement data in HL-2A are presented.

关键词： Bayesian inference Gaussian process tomography HL-2A Tikhonov tomography CIS

Precise and efficient insertion of A673T mutation in APP gene using MSYM

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Genes & Diseases 2024年第6期11卷 65-68页

作者： Qing Xia zijie Liu Xinyu Yang Jiaying Xiao Xue Zhao yu Zhao Feifei Zheng Fangliang Ge Ke Ye Lulu Liu Dayong Wang Xu Gao Department of Biochemistry and Molecular Biology Harbin Medical UniversityHarbinHeilongjiang 150000China Dongzhimen Hospital Beijing University of Chinese MedicineBeijing100700China Basic Medical Institute Heilongjiang Medical Science AcademyHarbinHeilongjiang150000China Translational Medicine Center of Northern China HarbinHeilongjiang 150000China Key Laboratory of Heilongjiang Province for Genetically Modified Animals Harbin Medical UniversityHarbinHeilongjiang 150000China

Alzheimer's disease(AD)is a progressive neurodegenerative disorder causing memory loss,cognitive decline,language impairment,and disorientation,which impose an enormous burden on caregivers and the public health sector.A673T as a protective mutation has great therapeutic potential in AD.1,2 Therefore,a combination of stem cell therapy and A673T mutation existing in natural people based on gene targeting techniques such as CRISPR-Cas9 have been suggested as promising and exciting new developments.

关键词： protective Alzheimer impairment

Bright, photostable and long-circulating NIR-Ⅱ nanoparticles for whole-process monitoring and evaluation of renal transplantation

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National Science Review 2024年第2期11卷 207-220页

作者： Rongyuan Zhang Ping Shen yu Xiong Tianjing Wu Gang Wang yucheng Wang Liping Zhang Han Yang Wei He Jian Du Xuedong Wei Siwei Zhang zijie Qiu Weijie Zhang Zheng Zhao Ben Zhong Tang Clinical Translational Research Center of Aggregation-Induced Emission The Second Affiliated HospitalSchool of MedicineSchool of Science and Engineering Shenzhen Institute of Aggregate Science and TechnologyThe Chinese University of Hong KongShenzhen(CUHK-Shenzhen) Center for AIE Research Shenzhen Key Laboratory of Polymer Science and TechnologyGuangdong Research Center for Interfacial Engineering of Functional MaterialsCollege of Materials Science and Engineering Shenzhen University School of Chemistry Xiangtan University HKUST-Shenzhen Research Institute Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction The Hong Kong University of Science and Technology Department of Urology The First Affiliated Hospital of Soochow University AIE Institute

Kidney transplantation is the gold standard for the treatment of end-stage renal diseases(ESRDs). However,the scarcity of donor kidneys has caused more and more ESRD patients to be stuck on the waiting list for transplant surgery. Improving the survival rate for renal grafts is an alternative solution to the shortage of donor kidneys. Therefore, real-time monitoring of the surgical process is crucial to the success of kidney transplantation, but efficient methods and techniques are lacking. Herein, a fluorescence technology based on bright, photostable and long-circulating aggregation-induced emission(AIE) active NIR-II nano-contrast agent DIPT-ICF nanoparticles for the whole-process monitoring and evaluation of renal transplantation has been reported. In the aggregated state, DIPT-ICF exhibits superior photophysical properties compared with the commercial dyes IR-26 and IR-1061. Besides, the long-circulating characteristic of the AIE nano-contrast agent helps to achieve renal angiography in kidney retrieval surgery,donor kidney quality evaluation, diagnosing vascular and ureteral complications, and assessment of renal graft reperfusion beyond renovascular reconstruction, which considerably outperforms the clinically approved indocyanine green(ICG).

关键词： aggregation-induced emission NIR-II imaging kidney transplantation nano-contrast agent angiography

DNMT3A:A Multifunctional Mediator of Cancer Progression

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Medicinal Plant 2024年第3期15卷 75-78页

作者： zijie WEI Jiaji ZHANG Ziqian KOU yu CHENG Department of Basic Medical Sciences Chengde Medical UniversityChegnde 067000China Department of Pathology Chengde Medical UniversityChengde 067000China

The advances in the research on the structure and function of DNMT3A and the role of DNMT3A in tumorigenesis and development were reviewed,including gynecologic cancers,hematologic tumors,melanoma,amelanoma,colorectal... 详细信息

关键词： DNMT3A Cancer Methylation

0.35%THz pulse conversion efficiency achieved by Ti:sapphire femtosecond laser filamentation in argon at 1 kHz repetition rate

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Opto-Electronic Advances 2022年第9期5卷 26-33页

作者： Zhiqiang yu Nan Zhang Jianxin Wang zijie Dai Cheng Gong Lie Lin Lanjun Guo Weiwei Liu Institute of Modern Optics Nankai UniversityTianjin 300350China Tianjin Key Laboratory of Micro-scale Optical Information Science and Technology Tianjin 300350China Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology Tianjin 300350China

In this study,an optical setup for generating terahertz(THz)pulses through a two-color femtosecond laser filament was carefully designed to achieve a precise overlap of two-color laser pulses in space and time.β-barium borate(BBO),α-BBO,and a dual-wavelength plate were used to compensate the phase delay of the two-color *** ofα-BBO could further realize the precise spatial overlap of the two beams by counteracting the walk-off *** maximum out-put THz pulse energy reached 21μJ in argon gas when using a commercial Ti:sapphire laser with a pulse energy of 6 mJ at a 1 kHz repetition *** corresponding conversion efficiency exceeded 0.35%.

关键词： femtosecond laser filaments walk-off effect conversion efficiency