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Physicochemical,rheological and antioxidant profiling of yogurt prepared from non-enzymatically and enzymatically hydrolyzed potato powder under refrigeration

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Food Science and Human Wellness 2023年第1期12卷 69-78页

作者： Ishtiaq Ahmad zhouyi xiong Hanguo xiong Rana Muhammad Aadil Nauman Khalid Allah Bakash Jvaid Lakhoo Zia-ud-din Asad Nawaz Noman Walayat Rao Sanaullah Khan College of Food Science and Technology Huazhong Agricultural UniversityWuhan 430070China Fisheries Research Institute Wuhan Academy of Agricultural SciencesWuhan 430207China National Institute of Food Science and Technology University of AgricultureFaisalabad 38000Pakistan Schools of Food and Agricultural Sciences University of Management and TechnologyLahore 54000Pakistan College of Food Science and Technology Zhejiang University of TechnologyHangzhou 310014China

Evidences show that the storage period greatly affects the quality of yogurt.In this study,three types of yogurt:control yogurt(CY),non-hydrolyzed potato powder yogurt(PPY)and enzymatically hydrolyzed potato powder yogurt(EHPPY)were prepared at 42℃ for 5 h and stored for 28 days at 4℃.The yogurts were evaluated for quality characteristics at different storage periods.Negligible differences in pH values,titratable acidities and viable counts were detected in all three types of yogurt during storage.However,compared to other yogurts,EHPPY exhibited desirable water holding capacity,throughout the storage period.Apart from this,sensory properties and antioxidant activities(2-diphenyl-1-picryl-hydrazyl(DPPH)free radical scavenging activity and ferric reducing antioxidant power(FRAP))of EHPPY were also significantly improved during the storage period.Furthermore,the storage(G’)and loss(G”)modulus of PPY,EHPPY were lower than CY at 4℃ while a hysteresis loop was shown by all yogurts at the temperature range of 4-50℃ indicating higher G’(elasticity)than G”(viscosity).Based on our findings,EHPP could be an important functional ingredient in improving the quality and storage stability of yogurt for its production at an industrial level.

关键词： Storage stability Potato powder Yogurt Rheology Microbiology Antioxidant activity

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A Dual Yamabe Flow and Related Integral Flows

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Chinese Annals of Mathematics,Series B 2024年第3期45卷 319-348页

作者： Jingang xiong School of Mathematical Sciences Laboratory of Mathematics and Complex Systems Ministry of Edu-cation Beijing Normal University

The author studies a family of nonlinear integral flows that involve Riesz potentials on Riemannian manifolds. In the Hardy-Littlewood-Sobolev (HLS for short)subcritical regime, he presents a precise blow-up profile exhibited by the flows. In the HLS critical regime, by introducing a dual Q curvature he demonstrates the concentrationcompactness phenomenon. If, in addition, the integral kernel matches with the Green’s function of a conformally invariant elliptic operator, this critical flow can be considered as a dual Yamabe flow. Convergence is then established on the unit spheres, which is also valid on certain locally conformally flat manifolds.

关键词： Hardy-Littlewood-Sobolev functional Dual Q curvature Integral flow 45K05 35B33

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Long non-coding RNAs with essential roles in neurodegenerative disorders

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Neural Regeneration Research 2024年第6期19卷 1212-1220页

作者： Wandi xiong Lin Lu Jiali Li Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences & Yunnan Province Kunming Institute of Zoology the Chinese Academy of Sciences Tsinghua-Peking Center for Life Sciences National Institute on Drug Dependence Peking University PKU/McGovern Institute for Brain Research Peking University Institute of Mental Health National Clinical Research Center for Mental Disorders Key Laboratory of Mental Health and Peking University Sixth Hospital Peking University

Recently, with the advent of high-resolution and high-throughput sequencing technologies, an increasing number of long non-coding RNAs(lncRNAs) have been found to be involved in the regulation of neuronal function in the central nervous system with specific spatiotemporal patterns, across different neurodegenerative diseases. However, the underlying mechanisms of lncRNAs during neurodegeneration remain poorly understood. This review provides an overview of the current knowledge of the biology of lncRNAs and focuses on introducing the latest identified roles, regulatory mechanisms, and research status of lncRNAs in Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. Finally, this review discusses the potential values of lncRNAs as diagnostic biomarkers and therapeutic targets for neurodegenerative diseases, hoping to provide broader implications for developing effective treatments.

关键词： Alzheimer’s disease amyotrophic lateral sclerosis biomarker Huntington’s disease long non-coding RNAs neurodegenerative diseases Parkinson’s disease therapy transcriptional regulation translational regulation

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Recent Progress in Bionic Hydrogels for Articular Cartilage:Tribological and Mechanical Characteristics

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Journal of Bionic Engineering 2024年第2期21卷 653-673页

作者： Mohammad Javan Almasi Dangsheng xiong School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing210094China

Cartilage regeneration and repair are considered clinical challenges since cartilage has limited capability for reconstruction.Although tissue-engineered materials have the ability to repair cartilage,they have weak mechanical characteristics and cannot resist long-term overload.On the other hand,surgery to replace the joint is frequently done to treat significant cartilage deterioration these days.However,the materials that are being used for replacement have high friction coefficients,lack shock absorption functions,and lack cushioning.Further research on natural articular cartilage structure and function may lead to bionic hydrogels,which have suitable physicochemical and biological characteristics(e.g.,tribological and mechanical properties and the ability to support loadbearing capability),but need improvements.Based on their tribological and mechanical characteristics,the current review highlights the most recent advancements of bionic hydrogels used for articular cartilage,highlighting both the field's recent progress and its potential for future research.For this reason,firstly,some important property improvement methods of bionic hydrogels are discussed and then,the recent findings of various research on the making of those bionic materials are provided and compared.It seems that by using some modifications such as product design,surface treatments,animal tests,controlling the isoelectric point of hydrogels,and computer simulation,the intended mechanical and tribological characteristics of natural articular cartilage may be attained by the bionic hydrogels.

关键词： Bionic hydrogel Articular cartilage Mechanical property Tribological property Lubrication

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Integrated Zoology’s collection of Wildlife Diseases Research Network

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Integrative Zoology 2024年第3期19卷 348-349页

作者： Wenhua xiong Institute of Zoology Chinese Academy of Sciences Office of the International Society of Zoological Sciences

The International Society of Zoological Sciences has developed a Wildlife Diseases Research Network(WDRN)in the world,with the collaboration of its partners such as the Working Group on Zoonotic Disease of the International Union of Biological Sciences(IUBS)(https://***/).WDRN is composed of a steering committee,a scientific committee,a research expert network,and collaborative partners.

关键词： partner committee IUB

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A Generalized Blow up Criteria with One Component of Velocity for 3D Incompressible MHD System

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Chinese Annals of Mathematics,Series B 2024年第2期45卷 253-264页

作者： Bin HAN Xi xiong Department of Mathematics Hangzhou Dianzi UniversityHangzhou 310018China

In this paper,the authors study the global regularity of the 3D magnetohydrodynamics system in terms of one velocity component.In particular,they establish a new Prodi-Serrin type regularity criterion in the framework... 详细信息

关键词： MHD Regularity Blow-up criterion

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Hole mobility enhancement in monolayer WSe2 p-type transistors through molecular doping

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Science China(Information Sciences) 2024年第6期67卷 207-213页

作者： Shiyuan LIU xiong xiong Xin WANG Xinhang SHI Ru HUANG Yanqing WU School of Integrated Circuits and Beijing Advanced Innovation Center for Integrated Circuits Peking University Wuhan National High Magnetic Field Center and School of Integrated Circuits Huazhong University of Science and Technology

Two-dimensional （2D） transition metal dichalcogenide （TMDC） semiconductor materials exhibit extraordinary electrical properties,holding promise for the realization of next-generation complementary metal-oxide-semiconductor （CMOS） devices at ultimate scaling.However,constrained by effective device doping strategies,the hole mobility and device performance of tungsten diselenide （WSe2） p-type transistors,especially monolayer chemical vapor deposition （CVD）-grown WSe2,have not met expectations.In this paper,an effective performance enhancement of monolayer WSe2p-type transistor was achieved through a molecular doping strategy.Synthesizing monolayer WSe2directly on SiO2back-gated substrates and leveraging energy band alignment design,4-nitrobenzenediazonium tetrafluoroborate （4-NBD） molecular dopant with a concentration of 10 m M was utilized to modulate the Fermi level position of monolayer WSe2for hole doping.The devices demonstrated a more than 98%increase in hole mobility,reaching up to 97 cm2·V-1·s-1while maintaining the current on/off ratio of 108.Monolayer p-type WSe2transistors with 1μm channel length exhibit a high drive current surpassing 176μA·μm-1,exceeding previous CVD-WSe2devices with similar channel length.This straightforward and effective approach to improving the electrical performance of WSe2transistors paves the way for advanced logic technologies based on transition metal dichalcogenide semiconductors.

关键词： CVD-grown WSe$_2$ molecular doping 4-NBD p-type transistors hole mobility

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Equivariant Chern Classes of Orientable Toric Origami Manifolds

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Chinese Annals of Mathematics,Series B 2024年第2期45卷 221-234页

作者： Yueshan xiong Haozhi ZENG School of Mathematics and StatisticsHuazhong University of Science and Technology Wuhan 430074China

A toric origami manifold,introduced by Cannas da Silva,Guillemin and Pires,is a generalization of a toric symplectic manifold.For a toric symplectic manifold,its equivariant Chern classes can be described in terms of the corresponding Delzant polytope and the stabilization of its tangent bundle splits as a direct sum of complex line bundles.But in general a toric origami manifold is not simply connected,so the algebraic topology of a toric origami manifold is more difficult than a toric symplectic manifold.In this paper they give an explicit formula of the equivariant Chern classes of an oriented toric origami manifold in terms of the corresponding origami template.Furthermore,they prove the stabilization of the tangent bundle of an oriented toric origami manifold also splits as a direct sum of complex line bundles.

关键词： Equivariant Chern classes Toric origami manifolds Unitary structures Spin structures

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Mesenchymal stem cell-derived extracellular vesicles as a cell-free therapy for traumatic brain injury via neuroprotection and neurorestoration

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Neural Regeneration Research 2024年第1期19卷 49-54页

作者： Ye xiong Asim Mahmood Michael Chopp Department of Neurosurgery Henry Ford HospitalDetroitMIUSA Department of Neurology Henry Ford HospitalDetroitMIUSA Department of Physics Oakland UniversityRochesterMIUSA

Traumatic brain injury is a serious and complex neurological condition that affects millions of people worldwide.Despite significant advancements in the field of medicine,effective treatments for traumatic brain injury remain limited.Recently,extracellular vesicles released from mesenchymal stem/stromal cells have emerged as a promising novel therapy for traumatic brain injury.Extracellular vesicles are small membrane-bound vesicles that are naturally released by cells,including those in the brain,and can be engineered to contain therapeutic cargo,such as anti-inflammatory molecules,growth factors,and microRNAs.When administered intravenously,extra cellular vesicles can cross the blood-brain barrier and deliver their cargos to the site of injury,where they can be taken up by recipient cells and modulate the inflammatory response,promote neuroregeneration,and improve functional outcomes.In preclinical studies,extracellular vesicle-based therapies have shown promising results in promoting recove ry after traumatic brain injury,including reducing neuronal damage,improving cognitive function,and enhancing motor recovery.While further research is needed to establish the safety and efficacy of extra cellular vesicle-based therapies in humans,extra cellular vesicles represent a promising novel approach for the treatment of traumatic brain injury.In this review,we summarize mesenchymal ste m/stromal cell-de rived extracellular vesicles as a cell-free therapy for traumatic brain injury via neuroprotection and neurorestoration and brainderived extracellular vesicles as potential biofluid biomarkers in small and large animal models of traumatic brain injury.

关键词： biomarkers extracellular vesicles functional outcome mesenchymal stem/stromal cells neuroinflammation neuroplasticity neuroprotection traumatic brain injury

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A wide-linear-range and low-hysteresis resistive strain sensor made of double-threaded conductive yarn for human movement detection

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Journal of Materials Science & Technology 2024年第5期172卷 202-212页

作者： Fei Huang Jiyong Hu xiong Yan Shanghai Frontier Science Research Center for Modern Textiles Donghua UniversityShanghai 201620China

Yarn-based flexible strain sensors with advantages in wearability and integrability have attracted wide at-tention.However,it is still a big challenge to achieve yarn-based strain sensors with a wide linear strain range,low hysteresis,and durability synchronously that can be used for full range detection of human body motions.Herein,a new structure,double-threaded conductive yarn with rhythmic strain distribu-tion,is reported to markedly widen the linear strain range of microcrack-based stretchable strain sensors.A new method of winding and thermally adhering hot-melt filaments on the surface of the elastic fiber is used to achieve double-threaded yarn(DTY)with rhythmic strain distribution.The proposed strategy,the integration of heterogeneous materials,is reported to significantly reduce the mechanical hysteresis of composite yarns.Rhythmic strain distribution of the DTY during stretching causes multi-level micro-cracks in different regions of the carbon nanotube(CNT)conductive layer deposited on the surface of the DTY.Besides,the sensing performance of DTY-based strain sensor can be adjusted by designing the structural parameters.The final prepared flexible strain sensor has the advantages of a wide linear strain range(100%),great sensitivity(GF=12.43),low hysteresis,rapid response(158 ms),high repeatability(>2000 cycles at 50%strain),and hydrophobicity,etc.The sensor can monitor human motion repeatedly and stably well,and shows great advantages in flexible wearable devices.

关键词： Double-threaded yarn Strain redistribution Hysteresis Human motion monitoring

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