Recent Progress in Bionic Hydrogels for Articular Cartilage:Tribological and Mechanical Characteristics

作     者：Mohammad Javan Almasi Dangsheng Xiong Mohammad Javan Almasi;Dangsheng Xiong

作者机构：School of Materials Science and EngineeringNanjing University of Science and TechnologyNanjing210094China 

出 版 物：《Journal of Bionic Engineering》 (仿生工程学报（英文版）)

年 卷 期：2024年第21卷第2期

页      面：653-673页

核心收录：

学科分类：081702[工学-化学工艺] 08[工学] 0817[工学-化学工程与技术] 

基　　金：supported by National Natural Science Foundation of China(Grant No.51975296) 

主　　题：Bionic hydrogel Articular cartilage Mechanical property Tribological property Lubrication 

摘      要：Cartilage regeneration and repair are considered clinical challenges since cartilage has limited capability for *** tissue-engineered materials have the ability to repair cartilage,they have weak mechanical characteristics and cannot resist long-term *** the other hand,surgery to replace the joint is frequently done to treat significant cartilage deterioration these ***,the materials that are being used for replacement have high friction coefficients,lack shock absorption functions,and lack *** research on natural articular cartilage structure and function may lead to bionic hydrogels,which have suitable physicochemical and biological characteristics(e.g.,tribological and mechanical properties and the ability to support loadbearing capability),but need *** on their tribological and mechanical characteristics,the current review highlights the most recent advancements of bionic hydrogels used for articular cartilage,highlighting both the field s recent progress and its potential for future *** this reason,firstly,some important property improvement methods of bionic hydrogels are discussed and then,the recent findings of various research on the making of those bionic materials are provided and *** seems that by using some modifications such as product design,surface treatments,animal tests,controlling the isoelectric point of hydrogels,and computer simulation,the intended mechanical and tribological characteristics of natural articular cartilage may be attained by the bionic hydrogels.