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Primary retroperitoneal mucinous cystadenoma:Report of a case and review of the literature

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World Journal of Gastroenterology 2008年第37期14卷 5769-5772页

作者： sheng-Lei Yan Ho Lin Chien-Long Kuo Hurng-sheng wu Ming-Ho Huang Yueh-Tsung Lee Division of Gastroenterology Departmentof Internal Medicine Chang Bing Show Chwan MemorialHospital Changhua County 505 Taiwan China Department of Life Sciences NationalChun~ Hsing University. Taichung City 402. Taiwan. China Department of Pathology Show ChwanMemorial Hospital Changhua City 500 Taiwan China Division of GeneralSurgery Department of Surgery Show Chwan MemorialHospital Changhua City500 Taiwan China Division of General Surgery Departmentof Surgery Chang Bing Show Chwan Memorial HospitalChanghua County 505 Taiwan China

Primary retroperitoneal mucinous cystadenomas (RMCs) are very rare and their biological behavior and histogenesis remain speculative. An accurate preoperative diagnosis of these tumors is difficult because no effective diagnostic measures have been established. We describe a 29-year-old woman with abdominal pain and a palpable mass. Computed tomography (CT) of the abdomen revealed a retroperi-toneal cystic mass which was resected successfully at laparotomy. Histopathological examination of the resected mass confirmed the diagnosis of RMC. There was no evidence of disease 2 years after surgery.

关键词： Retroperitoneal Mucinous cystadenoma Cystic mass Clinical features

耐热钢12Cr1MoV在NaHCO_3溶液中早期腐蚀行为的电化学噪声研究

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材料工程 2011年第8期39卷 8-13页

作者：田志强孔小东吴港王源升海军工程大学化学与材料系武汉430033 四川大学高分子材料工程国家重点实验室成都610041

运用电化学手段测试和分析耐热钢12Cr1MoV在含不同浓度Cl-的0.5mol/L NaHCO3溶液体系中的早期腐蚀行为。电化学噪声测量技术记录12Cr1MoV在不同介质条件下早期腐蚀过程的噪声图谱,通过腐蚀形貌观察和极化曲线、微观分析等手段验证电化... 详细信息

运用电化学手段测试和分析耐热钢12Cr1MoV在含不同浓度Cl-的0.5mol/L NaHCO3溶液体系中的早期腐蚀行为。电化学噪声测量技术记录12Cr1MoV在不同介质条件下早期腐蚀过程的噪声图谱,通过腐蚀形貌观察和极化曲线、微观分析等手段验证电化学噪声分析结果。结果显示,12Cr1MoV基体与HCO3-反应形成腐蚀产物膜。Cl-的加入破坏钝化膜,形成电化学噪声点蚀特征峰,HCO3-的作用使亚稳态点蚀得到修复。随着Cl-浓度增大,亚稳态点蚀噪声峰波动幅度变大,形核率λ增大,点蚀诱导期缩短。极化曲线测试结果、腐蚀形貌观察、微观分析结果和电化学噪声分析结果有良好的一致性。

关键词： 12Cr1MoV 耐蚀性电化学噪声

The High Energy X-ray telescope (HE) onboard the Insight-HXMT astronomy satellite

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Science China(Physics,Mechanics & Astronomy) 2020年第4期63卷 20-34页

作者： CongZhan Liu YiFei Zhang XuFang Li XueFeng Lu zhi Chang ZhengWei Li AiMei Zhang YongJie Jin HuiMing Yu Zhao Zhang MinXue Fu YiBao Chen JianFeng Ji YuPeng Xu JingKang Deng RenCheng Shang GuoQing Liu FangJun Lu ShuangNan Zhang YongWei Dong TiPei Li Mei wu YanGuo Li HuanYu Wang BoBing wu YongJie Zhang zhi Zhang ShaoLin Xiong Yuan Liu Shu Zhang HongWei Liu YiJung Yang Fan Zhang Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China University of Chinese Academy of Sciences Beijing 100049China

The Insight-Hard X-ray Modulation Telescope(Insight-HXMT) is a broadband X-ray and γ-ray(1-3000 ke V) astronomy satellite. One of its three main telescopes is the High Energy X-ray telescope(HE). The main detector plane of HE comprises 18 Na I(Tl)/Cs I(Na) phoswich detectors, where Na I(Tl) is used as the primary detector to measure ~ 20-250 ke V photons incident from the field of view(FOV) defined by collimators, and Cs I(Na) is used as the active shielding detector to Na I(Tl) by pulse shape discrimination. Additionally, Cs I(Na) is used as an omnidirectional γ-ray monitor. The HE collimators have a diverse FOV,i.e. 1.1°×5.7°(15 units), 5.7°×5.7°(2 units), and blocked(1 unit). Therefore, the combined FOV of HE is approximately5.7°×5.7°. Each HE detector has a diameter of 190 mm resulting in a total geometrical area of approximately 5100 cm2, and the energy resolution is ~15% at 60 ke V. For each recorded X-ray event by HE, the timing accuracy is less than 10 μs and the deadtime is less than 10 μs. HE is used for observing spectra and temporal variability of X-ray sources in the 20-250 ke V band either by pointing observations for known sources or scanning observations to unveil new sources. Additionally, HE is used for monitoring the γ-ray burst in 0.2-3 Me V band. This paper not only presents the design and performance of HE instruments but also reports results of the on-ground calibration experiments.

关键词： X-ray telescope HXMT calibration scintillation detector

储罐爆炸碎片最可能抛射距离的Monte-Carlo(蒙特卡罗)数值模拟

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中国安全科学学报 2008年第3期18卷 15-21页

作者：杨玉胜吴宗之中国矿业大学(北京)资源与安全工程学院中国安全生产科学研究院

在总结前人工作的基础上,推导了储罐爆炸碎片抛射距离的理论计算公式,并给出具体的计算方法;分析了计算参数的不确定性,同时介绍用Monte-Carlo方法模拟高压储罐爆炸时碎片抛射距离的算法;在数值模拟结果的基础上,计算了碎片抛射距离的... 详细信息

在总结前人工作的基础上,推导了储罐爆炸碎片抛射距离的理论计算公式,并给出具体的计算方法;分析了计算参数的不确定性,同时介绍用Monte-Carlo方法模拟高压储罐爆炸时碎片抛射距离的算法;在数值模拟结果的基础上,计算了碎片抛射距离的分布函数和概率密度函数,引入最可能抛射距离的概念,并指出可以用此来确定碎片抛射的危害范围。该方法对于定量评价储罐爆炸碎片危害性,减缓和控制碎片产生的风险,具有重要的意义。

关键词：爆炸事故最可能抛射距离蒙特卡罗(Monte—Carlo)法碎片数值模拟

Combined Influence of Insulin Resistance and Inflammatory Biomarkers on Type 2 Diabetes:A Population-based Prospective Cohort Study of Inner Mongolians in China

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Biomedical and Environmental Sciences 2018年第4期31卷 300-305页

作者： QIU Qiao Yan ZHANG Bei Lei ZHANG Ming zhi wu Jia Hui ZHOU Jing Wen LIANG Zhu ZHANG Yong Hong ZHANG Shao Yan Department of Epidemiology School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Medical College of Soochow University Suzhou 215123 Jiangsu China The Second Affiliated Hospital of Zhejiang Chinese Medical University Hangzhou 310000 Zhejiang China wujin District Center for Disease Control and Prevention Changzhou 213159 Jiangsu China Nanjing Brain Hospital Nanjing 210029 JiangsuChina Kunshan Center for Disease Control and Prevention Suzhou 215123 Jiangsu China

This prospective study was designed to examine the combined influence of insulin resistance（IR）and inflammatory biomarker levels on type 2 diabetes mellitus（T2DM）among 1,903Inner Mongolians.

关键词： CRP DM Combined Influence of Insulin Resistance and Inflammatory Biomarkers on Type 2 Diabetes A Population-based Prospective Cohort Study of Inner Mongolians in China IR

Efficacy and Safety of Aspirin for Prevention of Hepatocellular Carcinoma:An Updated Meta-analysis

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Journal of Clinical and Translational Hepatology 2022年第5期10卷 835-846页

作者： Lun-Jie Yan sheng-Yu Yao Hai-Chao Li Guang-Xiao Meng Kai-Xuan Liu Zi-Niu Ding Jian-Guo Hong zhi-Qiang Chen Zhao-Ru Dong Tao Li Department of General Surgery Qilu HospitalShandong UniversityJinanShandongChina Department of Hepatobiliary Surgery The second Hospital of Shandong UniversityJinanShandongChina

Background and Aims:Previous meta-analyses have shown that aspirin use may reduce the risk of hepatocellular carcinoma(HCC).However,the optimal dose,frequency,and duration of aspirin use or the safety and efficacy of aspirin in target populations for HCC prevention remain *** study aim was to investigate the efficacy and safety of aspirin for prevention of ***:Publications were retrieved by a comprehensive literature research of several *** on a random-effects model,hazard ratios(HRs)and the corresponding 95%confidence intervals(CIs)were used to assess the pooled *** dose-response relationship between aspirin use and HCC risk was assessed with a restricted cubic spline ***:Twenty-two studies were included in the *** use was associated with a reduced risk of HCC(HR=0.64,95%CI:0.56–0.75).The effect was robust across sex and age;however,women and the non-elderly had the greatest benefit from aspirin *** preventive effect was well reproduced in those with *** use and long-term use of aspirin appeared to offer greater *** 100 mg/d was associated with maximum reduction of HCC *** use did slightly increase the risk of bleeding(HR=1.14,95%CI:1.02–1.27).Conclusions:Our meta-analysis confirmed that use of aspirin significantly reduced the incident risk of *** and long-term aspirin use offers a greater *** use was associated with an increased risk of *** recommend 100 mg/d aspirin as a feasible dose for further research on primary prevention of HCC in a broad at-risk population.

关键词： Aspirin Hepatocellular carcinoma Prevention Meta-analysis Doseresponse analysis

Diagnosis,treatment,and prevention of severe acute hepatitis of unknown etiology in children

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World Journal of Pediatrics 2022年第8期18卷 538-544页

作者： Ying‑Hu Chen Jin‑Gan Lou Zi‑Hao Yang Qing‑Jiang Chen Chun‑Zhen Hua sheng Ye Chen‑Mei Zhang Jie Chen Zong‑Wei Huang Jin‑Dan Yu zhi‑Gang Gao Qiang Shu Infectious Disease Department National Clinical Research Center for Child HealthChildren’s HospitalZhejiang University School of MedicineHangzhou 310052China Gastroenterology Department National Clinical Research Center for Child HealthChildren’s HospitalZhejiang University School of MedicineHangzhou 310052China PICU National Clinical Research Center for Child HealthChildren’s HospitalZhejiang University School of MedicineHangzhou 310052China General Surgery Department National Clinical Research Center for Child HealthChildren’s HospitalZhejiang University School of MedicineBinsheng Road 3333Hangzhou 310052China

Background Severe acute hepatitis of unknown etiology in children has recently exhibited a global trend of concentrated *** review aimed to summarize the current available information regarding the outbreak of severe acute hepatitis and introduce our hospital’s previous experiences with the diagnosis and treatment of severe acute hepatitis for *** sources Websites including the UK Health Security Agency,European Centre for Disease Prevention and Control,CDC,WHO,and databases including PubMed/Medline,Cochrane Library,Embase and Web of Science were searched for articles on severe acute hepatitis in *** As of May 26,2022,a total of 650 cases have been reported in 33 countries;at least 38(6%)children required liver transplantation,and nine(1%)*** are predominantly aged between 3 and 5 years old,and there are no epidemiological links among *** common manifestations are jaundice,vomiting and pale *** tested positive in most cases,and SARS-CoV-2 and other viruses were detected in a few cases,but virus particles were not found in liver *** immunohistochemistry showed immunoreactivity in the intrasinusoidal lumen from some liver *** hierarchical treatment includes symptomatic and supportive therapy,management of coagulation disorders and hepatic encephalopathy,artifcial liver support,and liver transplantation(approximately 6%–10%of cases require liver transplant).Conclusions The etiology of this severe acute hepatitis in children is not *** clinical features are severe acute hepatitis with signifcantly elevated liver *** need to be alert to children with hepatitis.

关键词： Acute Hepatitis Diagnosis Epidemiology Pediatrics Treatment

利用光纤空间M-Z干涉仪测量压电陶瓷相移系数

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压电与声光 2009年第1期31卷 47-49页

作者：张建亮盛新志吴重庆北京交通大学光信息科学与技术研究所发光与光信息技术教育部重点实验室北京100044

提出了一种利用光纤空间M-Z干涉仪测量压电陶瓷(PZT)相位调制器相移系数的新方法。光纤空间M-Z干涉仪的空间干涉场图与PZT的相移呈单值函数,可有效克服出射光强与相移呈多值函数的问题。设计了测试系统并应用该系统实际测量了一种PZT的... 详细信息

提出了一种利用光纤空间M-Z干涉仪测量压电陶瓷(PZT)相位调制器相移系数的新方法。光纤空间M-Z干涉仪的空间干涉场图与PZT的相移呈单值函数,可有效克服出射光强与相移呈多值函数的问题。设计了测试系统并应用该系统实际测量了一种PZT的相移系数,对结果进行了数字拟合,线性性好。与已有的理论计算和根据光强测量的方法比较,这种方法具有更高的准确性和重复性。PZT相位调制器是光纤干涉系统中的重要组成部分,这种测定相移系数的新方法,可广泛用于各种光纤干涉系统中。

关键词：压电陶瓷相位调制器相移系数光纤M-Z干涉仪

Classification of four distinct osteoarthritis subtypes with a knee joint tissue transcriptome atlas

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Bone Research 2020年第4期8卷 406-415页

作者： Chunhui Yuan Zongyou Pan Kun Zhao Jun Li Zixuan sheng Xudong Yao Hua Liu Xiaolei Zhang Yang Yang Dongsheng Yu Yu Zhang Yuzi Xu zhi-Yong Zhang Tianlong Huang Wanlu Liu Hongwei Ouyang Dr.Li Dak Sum&Yip Yio Chin Center for Stem Cells and Regenerative Medicine and Department of Orthopedic Surgery of the Second Affiliated HospitalZhejiang University School of MedicineHangzhouChina Zhejiang University-University of Edinburgh Institute Zhejiang University School of Medicineand Key Laboratory of Tissue Engineering and Regenerative Medicine of Zhejiang ProvinceZhejiang University School of MedicineHangzhouChina Department of Sports Medicine Zhejiang University School of MedicineHangzhouChina Department of Orthopedics The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhouChina China Orthopedic Regenerative Medicine Group(CORMed) HangzhouChina Department of Orthopedics Zhejiang Provincial People’s HospitalHangzhou Medical CollegeHangzhouChina Translational Research Centre of Regenerative Medicine and 3D Printing Technologies of Guangzhou Medical University State Key Laboratory of Respiratory DiseaseThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhouChina The Second Xiangya Hospital of Central South University ChangshaChina

The limited molecular classifications and disease signatures of osteoarthritis(OA)impede the development of prediagnosis and targeted therapeutics for OA *** classify and understand the subtypes of OA,we collected three types of tissue including cartilage,subchondral bone,and synovium from multiple clinical centers and constructed an extensive transcriptome atlas of OA *** applying unsupervised clustering analysis to the cartilage transcriptome,OA patients were classified into four subtypes with distinct molecular signatures:a glycosaminoglycan metabolic disorder subtype(C1),a collagen metabolic disorder subtype(C2),an activated sensory neuron subtype(C3),and an inflammation subtype(C4).Through ligand-receptor crosstalk analysis of the three knee tissue types,we linked molecular functions with the clinical symptoms of different OA *** example,the Gene Ontology functional term of vasculature development was enriched in the subchondral bone-cartilage crosstalk of C2 and the cartilage-subchondral bone crosstalk of C4,which might lead to severe osteophytes in C2 patients and apparent joint space narrowing in C4 *** on the marker genes of the four OA subtypes identified in this study,we modeled OA subtypes with two independent published RNA-seq datasets through random forest *** findings of this work contradicted traditional OA diagnosis by medical imaging and revealed distinct molecular subtypes in knee OA patients,which may allow for precise diagnosis and treatment of OA.

关键词： diagnosis subtypes knee