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Intrapartum and early postpartum glycemic profiles in women with gestational diabetes mellitus:an observational study

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Chinese Medical Journal 2022年第21期135卷 2547-2553页

作者： Yu Ding xueying zheng Yujie Liu Tian Wei Tong Yue Siqi Wang Suyu Chen Jianping Weng Sihui Luo Department of Endocrinology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230001China Department of Obstetrics and Gynecology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230001China Institute of Endocrine and Metabolic Diseases The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230001China

Background: Data on the glycemic profile of pregnant women with gestational diabetes mellitus (GDM) during the perinatal period are sparse. This study described the intrapartum and early postpartum glucose profiles among pregnant women with GDM, and analyzed factors potentially affecting glycemic parameters during the ***: This was a prospective observational study conducted from March 2020 to November 2021. Pregnant women with GDM receiving lifestyle interventions alone during pregnancy and matched women with non-diabetic pregnancies (NDPs) were enrolled from among patients admitted to the obstetrics department for childbirth. Glucose monitoring was performed via a flash glucose monitoring (FGM) system on admission, and glucose readings during labor and early postpartum were analyzed. The clinical characteristics and FGM-based parameters of participants in the two groups were ***: A total of 124 participants (mean age: 29.5 ± 3.5 years, 92 [74.2%] primipara) were included in the final analysis. A total of 17,571 glucose readings were retrieved. There were no significant differences in clinical characteristics between the GDM (n = 60) and NDP (n = 64) groups. The average glucose level was 92.2 mg/dL, and the level was higher in the GDM group (95.5 ± 12.1 mg/dLvs. 89.1 ± 13.4 mg/dL,P = 0.008) during the intrapartum and early postpartum periods. The data were split into the intrapartum period (from the start of labor to delivery of the placenta) and the early postpartum period (within 24 h after placental delivery) for analysis. During intrapartum, women with GDM exhibited glycemic profiles and fluctuations similar to those in the NDP group. However, women with GDM had higher postpartum glucose levels (97.7 ± 13.4 mg/dLvs. 90.8 ± 15.3 mg/dL,P = 0.009), a longer time spent >140 mg/dL (8.7 ± 9.3%vs. 5.9 ± 10.3%,P = 0.011), and greater glycemic fluctuations than those with NDP. Postpartum hyperglycemia in GDM might be associated with high parity a

关键词： Blood glucose Flash glucose monitoring Gestational diabetes mellitus Glycemic profiles

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Multi-scenario Simulation and Spatial-temporal Analysis of LUCC in China's Coastal Zone Based on Coupled SD-FLUS Model

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Chinese Geographical Science 2024年第4期34卷 579-598页

作者： HOU Xiyong SONG Baiyuan ZHANG xueying WANG Xiaoli LI Dong Yantai Institute of Coastal Zone Research Chinese Academy of SciencesYantai 264003China Shandong Key Laboratory of Coastal Environmental Processes Yantai 264003China CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation Yantai Institute of Coastal Zone ResearchChinese Academy of SciencesYantai 264003China Shanghai Fuxiong Environmental Technology Corporation Shanghai 200433China

Increased human activities in China's coastal zone have resulted in the depletion of ecological land ***,conducting current and future multi-scenario simulation research on land use and land cover change(LUCC)is crucial for guiding the healthy and sustainable development of coastal *** dynamic(SD)-future land use simulation(FLUS)model,a coupled simulation model,was developed to analyze land use dynamics in China's coastal *** model encompasses five scenarios,namely,SSP1-RCP2.6(A),SSP2-RCP4.5(B),SSP3-RCP4.5(C),SSP4-RCP4.5(D),and SSP5-RCP8.5(E).The SD model simulates land use demand on an annual basis up to the year ***,the FLUS model determines the spatial distribution of land use for the near term(2035),medium term(2050),and long term(2100).Results reveal a slowing trend in land use changes in China's coastal zone from 2000–*** these changes,the expansion rate of construction land was the highest and exhibited an annual *** 2100,land use predictions exhibit high accuracy,and notable differences are observed in trends across *** summary,the expansion of production,living,and ecological spaces toward the sea remains *** A emphasizes reduced land resource dependence,benefiting ecological land *** B witnesses an intensified expansion of artificial *** C sees substantial land needs for living and production,while Scenario D shows coastal forest and grassland ***,in Scenario E,the conflict between humans and land *** study presents pertinent recommendations for the future development,utilization,and management of coastal areas in *** research contributes valuable scientific support for informed,long-term strategic decision making within coastal regions.

关键词： land use and land cover change(LUCC) multi-scenario simulation system dynamic-future land use simulation(SD-FLUS)model SSP-RCP scenarios model coupling China's coastal zone

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Tailoring NH_(4)^(+)storage by regulating oxygen defect in ammonium vanadate

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Green Energy & Environment 2024年第7期9卷 1171-1182页

作者： Yanyan Liu Ziyi Feng Hanmei Jiang xueying Dong Changgong Meng Yifu Zhang State Key Laboratory of Fine Chemicals School of Chemical EngineeringDalian University of TechnologyDalian116024China College of Environmental and Chemical Engineering Dalian UniversityDalian116622China

Defect engineering is an effective strategy for modifying the energy storage materials to improve their electrochemical ***,the impact of oxygen defect and its content on the electrochemical performances in the burgeoning aqueous NH_(4)^(+)storage field remains ***,for the first time in this work,an oxygen-defective ammonium vanadate[(NH_(4))_(2)V_(10)O_(25)·8H_(2)O,denoted as Od-NHVO]with a novel 3D porous flower-like architecture was achieved via the reduction of thiourea in a mild reaction condition,which is a facile method that can realize the intention to regulate the oxygen defect content,with the capability of *** as-prepared Od_M-NHVO with moderate oxygen defect content can deliver a stable specific capacitance output(505 F g^(-1),252 mAh g^(-1)at 0.5 A g^(-1)with~80% capacitance retention after 10,000 cycles),which benefits from extra active sites,unimpeded NH_(4)^(+)-migration path and relatively high structure *** contrast,low oxygen defect content will lead to the torpid electrochemical reaction kinetics while too high content of it will reduce the chargestorage capability and induce structural *** superior NH_(4)^(+)-storage behavior is achieved with the reversible intercalation/deintercalation process of NH_(4)^(+)accompanied by forming/breaking of hydrogen *** expected,the assembled flexible OdM-NHVO//PTCDI quasi-solid-state hybrid supercapacitor(FQSS HSC)also exhibits high areal capacitance,energy density and reliable *** work provides a new avenue for developing materials with oxygen-deficient structure for application in various aqueous non-metal cation storage systems.

关键词： Ammonium vanadate Oxygen defect Ammonium-ion storage Hybrid supercapacitors Electrochemical performance

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Controlled growth of vertically stacked In_(2)Se_(3)/WSe_(2) heterostructures for ultrahigh responsivity photodetector

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Nano Research 2024年第3期17卷 1856-1863页

作者： Cheng Zhang Biyuan zheng Guangcheng Wu xueying Liu Jiaxin Wu Chengdong Yao Yizhe Wang Zilan Tang Ying Chen Lizhen Fang Luying Huang Dong Li Shengman Li Anlian Pan Key Laboratory for Micro-Nano Physics and Technology of Hunan Province State Key Laboratory of Chemo/Biosensing and ChemometricsCollege of Materials Science and EngineeringHunan UniversityChangsha 410082China

Transition metal dichalcogenides(TMDCs)are promising candidates for future optoelectronic devices accounting for their high carrier mobility and excellent quantum ***,the limited light absorption efficiency in atomically thin layers significantly hinders photocarrier generation,thereby impairing the optoelectronic performance and hindering practical ***,we successfully synthesized In_(2)Se_(3)/WSe_(2) heterostructures through a typical two-step chemical vapor deposition(CVD)*** In_(2)Se_(3) nanosheet with strong light absorption capability,serving as the light absorption layer,was integrated with the monolayer WSe_(2),enhancing the photosensitivity of WSe_(2) *** laser irradiation with a wavelength of 520 nm,the In_(2)Se_(3)/WSe_(2) heterostructure device shows an ultrahigh photoresponsivity with a value as high as 2333.5 A/W and a remarkable detectivity reaching up to 6.7×10^(12) Jones,which is the highest among almost the reported TMDCs-based heterostructures grown via CVD even some fabricated by mechanical exfoliation(ME).Combing the advantages of CVD method such as large scale,high yield,and clean interface,the In_(2)Se_(3)/WSe_(2) heterostructures would provide a novel path for future high-performance optoelectronic device.

关键词： transition metal dichalcogenides(TMDCs) In_(2)Se_(3) heterostructure photodetector ultrahigh responsivity

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我国民族文化融入创意产业发展浅探

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改革与战略 2010年第10期26卷 133-135页

作者：郑雪英台州职业技术学院经济贸易系浙江台州318000

当前,全球正兴起创意产业的热潮。创意产业可以引导我国产业结构优化的方向,只有立足本民族独特的文化资源,走差异化的道路,才能在世界创意产业发展浪潮中有鲜明的个性和强劲的竞争力。我国发展创意产业也应该立足于我国本民族文化资源... 详细信息

当前,全球正兴起创意产业的热潮。创意产业可以引导我国产业结构优化的方向,只有立足本民族独特的文化资源,走差异化的道路,才能在世界创意产业发展浪潮中有鲜明的个性和强劲的竞争力。我国发展创意产业也应该立足于我国本民族文化资源,突出民族个性和自身优势,利用优秀的民族传统发展创意产业,创意产业的发展才有持久发展的营养和动力。

关键词：创意产业民族文化传承与繁荣

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食管静脉曲张一级预防对首诊原发性肝细胞癌患者预后的影响

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临床误诊误治 2024年第12期37卷 31-35页

作者：罗咏萍古代娇陈宗华刘毅张键黄洁郑学颖杨志慧黄亚娜曹敏唐欢宜宾市第二人民医院消化内科

目的探讨内镜下食管静脉套扎术(EVL)作为食管静脉曲张一级预防措施,对原发性肝细胞癌(HCC)患者预后的影响。方法选择2020年1月至2022年12月收治的首诊HCC患者149例,按随机数字表法分为观察组75例和对照组74例。观察组接受EVL治疗,对照... 详细信息

目的探讨内镜下食管静脉套扎术(EVL)作为食管静脉曲张一级预防措施,对原发性肝细胞癌(HCC)患者预后的影响。方法选择2020年1月至2022年12月收治的首诊HCC患者149例,按随机数字表法分为观察组75例和对照组74例。观察组接受EVL治疗,对照组未接受EVL治疗。监测2组患者食管静脉出血和静脉曲张改善情况,并记录随访期间患者的生存情况,采用COX回归分析HCC患者预后不良的影响因素。结果观察组治疗后3、6、12个月食管静脉出血率均显著低于对照组(P<0.05)。观察组食管静脉曲张改善总有效率[76.00%(57/75)]显著高于对照组[59.46%(44/74)](P<0.05)。观察组总病死率[18.67%(14/75)]、因消化道出血病死率[4.00%(3/75)]均显著低于对照组[33.78%(25/74)、16.22%(12/74)](P<0.05)。Kaplan-Meier生存曲线显示,观察组总生存时间显著长于对照组(P<0.05)。多变量COX回归分析显示,EVL是HCC患者预后不良的独立保护因素(HR=0.529,95%CI:0.285,0.865,P<0.05)。结论EVL能显著降低HCC患者食管静脉出血的风险,并改善患者的预后,因此,在临床中EVL治疗可考虑作为HCC患者食管静脉曲张一级预防的首选治疗策略。

关键词：肝肿瘤食管静脉套扎术原发性肝细胞癌食管静脉曲张预后一级预防胃肠出血

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Milk fat globule membrane supplementation protects againstβ-lactoglobul-ininduced food allergy in mice via upregulation of regulatory T cells and enhancement of intestinal barrier in a microbiota-derived short-chain fatty acids manner

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Food Science and Human Wellness 2024年第1期13卷 124-136页

作者： Han Gong Tiange Li Dong Liang Jingxin Gao Xiaohan Liu xueying Mao Key Laboratory of Functional Dairy Ministry of EducationCollege of Food Science and Nutritional EngineeringChina Agricultural UniversityBeijing 100083China Henan Engineering Technology Research Center of Food Processing and Circulation Safety Control College of Food Science and TechnologyHenan Agricultural UniversityZhengzhou 450002China Applied Nutrition I China National Center for Food Safety Risk AssessmentBeijing 100022China

Milk fat globule membrane(MFGM),which contains abundant glycoproteins and phospholipids,exerts beneficial effects on intestinal health and *** aim of this study was to evaluate the protective effects and possible underlying mechanisms of MFGM on cow’s milk allergy(CMA)in aβ-lactoglobulin(BLG)-induced allergic mice *** was supplemented to allergic mice induced by BLG at a dose of 400 mg/kg body *** demonstrated that MFGM alleviated food allergy symptoms,decreased serum levels of lipopolysaccharide,pro-inflammatory cytokines,immunoglobulin(Ig)E,Ig G1,and Th2 cytokines including interleukin(IL)-4,while increased serum levels of Th1 cytokines including interferon-γand regulatory T cells(Tregs)cytokines including IL-10 and transforming growth factor-β.MFGM modulated gut microbiota and enhanced intestinal barrier of BLG-allergic mice,as evidenced by decreased relative abundance of Desulfobacterota,Rikenellaceae,Lachnospiraceae,and Desulfovibrionaceae,while increased relative abundance of Bacteroidetes,Lactobacillaceae and Muribaculaceae,and enhanced expressions of tight junction proteins including Occludin,Claudin-1 and zonula ***,MFGM increased fecal short-chain fatty acids(SCFAs)levels,which elevated G protein-coupled receptor(GPR)43 and GPR109A *** increased expressions of GPR43 and GPR109A induced CD103+dendritic cells accumulation and promoted Tregs differentiation in mesenteric lymph node to a certain *** summary,MFGM alleviated CMA in a BLG-induced allergic mice model through enhancing intestinal barrier and promoting Tregs differentiation,which may be correlated with SCFAs-mediated activation of *** findings suggest that MFGM may be useful as a promising functional ingredient against CMA.

关键词： Cow’s milk allergy Milk fat globule membrane Gut microbiota Short-chain fatty acid G protein-coupled receptor Regulatory T cell

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「部長通道」談法治

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中国法律（中英文版） 2016年第2期 23-28页

作者：王映 zheng xueying Yang Ying China Law

位於大會堂北大廳的百米「部長通道」,成為2016年全國兩會上備受矚目的一道風景線。在「部長通道」開通的14天中,共有34位部委相關負責人站在「部長通道」的話筒前主動答疑。從被記者們圍迫堵截到主動發聲,「部長通道」裹的部長們應對... 详细信息

位於大會堂北大廳的百米「部長通道」,成為2016年全國兩會上備受矚目的一道風景線。在「部長通道」開通的14天中,共有34位部委相關負責人站在「部長通道」的話筒前主動答疑。從被記者們圍迫堵截到主動發聲,「部長通道」裹的部長們應對媒體的態度經歷了從被動到主動的轉化。

关键词： Minister 法律援助 legal supervision regulations registration officials institutions disciplines distinguish

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The interventional effect of Polygonatum cyrtonema Hua polysaccharide on atherosclerosis in mice of different sexes

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Food Science and Human Wellness 2024年第1期13卷 370-380页

作者： Anjun Guo xueying Li Lihua Pan Qiangming Li Jianping Luo Xueqiang Zha Engineering Research Centre of Bioprocess of Ministry of Education Hefei University of TechnologyHefei 230009China School of Food and Biological Engineering Hefei University of TechnologyHefei 230009China Key Laboratory of Metabolism and Regulation for Major Disease of Anhui Higher Education Institutes Hefei University of TechnologyHefei 230009China

In the present study,we investigated the intervention effects of a purified Polygonatum cyrtonema polysaccharide(PCP)on high-fat diet(HFD)-induced atherosclerosis in male and female LDLr-/-*** showed that HFD caused severe dyslipidemia,atherosclerotic lesions,oxidative damages and inflammation in male and female mice,and these effects seemed to be more pronounced in males than in ***,the above variations could be dose-dependently reversed by PCP treatment,and the intervention effects on males were greater than those on *** factor kappa-B(NF-κB),mitogen-activated protein kinase(MAPKs)and protein kinase B(Akt)are 3 pivotal signaling pathways mediating the development of ***,PCP was also found to significantly decrease the phosphorylation of p65,p38,extracellular-regulated kinase 1/2(ERK1/2)and Akt,and increase the protein expression of inhibitor of NF-κB(IκB)in the aortas of male and female mice induced by *** together,these findings indicated that PCP could be effective for the prevention of atherosclerosis,and the intervention effect of PCP on male mice was more obvious than that of female mice.

关键词： Polygonatum cyrtonema polysaccharide Anti-atherosclerosis Sex

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Dendrimer-induced synthesis of porous organosilica capsules for enzyme encapsulation

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Frontiers of Chemical Science and Engineering 2024年第4期18卷 41-48页

作者： Ziyi Chu Boyu Zhang Zhenhua Wu Jiaxu Zhang Yiran Cheng xueying Wang Jiafu Shi Zhongyi Jiang School of Environmental Science&Engineering Tianjin UniversityTianjin 300072China Collaborative Innovation Center of Chemical Science and Engineering Tianjin 300072China State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China Key Laboratory for Green Chemical Technology of Ministry of Education School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300072China

Organic matter-induced mineralization is a green and versatile method for synthesizing hybrid nanostructured materials,where the material properties are mainly influenced by the species of natural biomolecules,linear synthetic polymer,or small molecules,limiting their ***,we adopted dendrimer poly(amidoamine)(PAMAM)as the inducer to synthesize organosilica-PAMAM network(OSPN)capsules for mannose isomerase(MIase)encapsulation based on a hard-templating *** structure of OSPN capsules can be precisely regulated by adjusting the molecular weight and concentration of PAMAM,thereby demonstrating a substantial impact on the kinetic behavior of the MIase@OSPN *** MIase@OSPN system was used for catalytic production of mannose from Dfructose.A mannose yield of 22.24% was obtained,which is higher than that of MIase in organosilica network capsules and similar to that of the free *** overall catalytic efficiency(kcat/Km)of the MIase@OSPN system for the substrate D-fructose was up to 0.556 s^(-1)·mmol^(-1)·***,the MIase@OSPN system showed excellent stability and recyclability,maintaining more than 50% of the yield even after 12 cycles.

关键词： enzyme immobilization enzyme catalysis organosilica networks capsules sugar biosynthesis

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