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Journal of Magnesium and Alloys 2024年第2期12卷 530-545页

作者： jiaxin zhang Xin Ding Ruirun Chen Wenchao Cao Jinshan zhang Rui Zhao National Key Laboratory for Precision Hot Processing of Metals Harbin Institute of TechnologyNo.92West Dazhi StreetHarbinHeilongjiang 150001China College of Materials Science and Engineering Taiyuan University of TechnologyNo.79West Yingze StreetTaiyuanShanxi 030024China

For the sake of improving the mechanical properties and corrosion resistance of biodegradable Mg alloy synergistically,various content of element V(0,0.05,0.10,0.15,0.20 wt.%)are introduced into an Mg-Zn-Y alloy with long-period stacking ordered(LPSO)structure,and the effects of V on its microstructure,mechanical properties and corrosion resistance are investigated *** results indicate that the grains are effectively refined by V addition,and the primaryα-Mg in Mg-Zn-Y-V0.1 alloy is most significantly refined,with grain size being decreased by 62%.The amount of 18R LPSO structure is increased owing to the V *** growth mode of the second phase(W-phase and 18R LPSO structure)is transformed to divorced growth pattern,which ascribes to the thermodynamic drive force of V to promote the nucleation of LPSO ***,18R LPSO structure presents a continuous *** to grains refinement and modification of second phase,the tensile strength and strain of alloys are both enhanced ***,the ultimate tensile strength and the elongation of V0.1 alloy are 254 MPa and 15.26%,which are 41%and 61%higher than those of V-free alloy,*** to the continuously distributed 18R LPSO structure with refined grains and stable product film,the weight loss and hydrogen evolution corrosion rates of V0.1 alloy are 7.1 and 6.2 mmy^(-1),respectively,which are 42.6%and 45.4%lower than those of V-free alloy.

关键词： Corrosion Mechanical property V-microalloying LPSO SKPFM

Effect of sodium starch octenyl succinate-based Pickering emulsion on the physicochemical properties of hairtail myofibrillar protein gel subjected to multiple freeze-thaw cycles

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Food Science and Human Wellness 2024年第2期13卷 1018-1028页

作者： Huinan Wang jiaxin zhang Xinran Liu Jinxiang Wang Xuepeng Li Jianrong Li Key Laboratory of Food Nutrition and Safety Ministry of EducationCollege of Food Science and EngineeringTianjin University of Science and TechnologyTianjin 300457China College of Food Science and Technology Bohai UniversityNational R&D Branch Center of Surimi and Surimi Products ProcessingJinzhou 121013China

A Pickering emulsion based on sodium starch octenyl succinate(SSOS)was prepared and its effects on the physicochemical properties of hairtail myofibrillar protein gels(MPGs)subjected to multiple freeze-thaw(F-T)cycles were *** whiteness,water-holding capacity,storage modulus(G')and texture properties of the MPGs were significantly improved by adding 1%-2%Pickering emulsion(P<0.05).Meanwhile,Raman spectral analysis demonstrated that Pickering emulsion promoted the transformation of secondary structure,enhanced hydrogen bonds and hydrophobic interactions,and promoted the transition of disulfide bond conformation from g-g-g to g-g-t and *** an emulsion concentration of 2%,theα-helix content decreased by 10.37%,while theβ-sheet content increased by 7.94%,compared to the *** F-T cycles,the structure of the MPGs was destroyed,with an increase in hardness and a decrease in whiteness and water-holding capacity,however,the quality degradation of MPGs was reduced with 1%-2%Pickering *** findings demonstrated that SSOS-Pickering emulsions,as potential fat substitutes,can enhance the gel properties and the F-T stability of MPGs.

关键词： Pickering emulsion Myofibrillar protein Gel properties Freeze-thaw stability Intermolecular interactions

Lactobacillus plantarum J26 alleviates alcohol-induced oxidative liver injury by regulating the Nrf2 signaling pathway

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Food Science and Human Wellness 2024年第4期13卷 2068-2078页

作者： Hongxuan Li Shasha Cheng Yuhong Wang Yilin Sun jiaxin zhang Mingshuang Sun Chaoxin Man Yu zhang Yujun Jiang Key Laboratory of Dairy Science Ministry of EducationCollege of Food Science and EngineeringNortheast Agricultural UniversityHarbin 150030China

Oxidative stress is one of the main ways to cause alcohol-induced liver injury,and alcoholic liver disease(ALD)has been a common health problem *** acid bacteria(LAB)is also considered as a potential treatment to alleviate alcohol-induced liver *** plantarum J26 is a LAB isolated from Chinese traditional fermented dairy products with excellent probiotic *** study aimed to establish a mice model of alcoholic liver injury through acute-on-chronic alcohol feeding and to study the alleviating effect of pre-intake of *** J26 on alcohol-induced oxidative liver injury and focus on its potential mechanism of alleviating *** results showed that pre-intake of *** J26 could improve liver pathological changes,reduce lipid accumulation,increase mitochondrial ATP and mitochondrial(mtDNA)levels,and alleviate liver *** addition,pre-intake *** J26 can improve the level of short-chain fatty acids(SCFAs)in the intestines in mice,short chain fatty acids can be used as a signaling molecule activation of nuclear factor E2-related factor 2(Nrf2)signaling pathway to alleviate liver oxidative stress,and maintain mitochondrial homeostasis by regulating the expression of genes related to mitochondrial dynamics and autophagy,thereby reducing cell apoptosis to alleviate alcohol-induced oxidative liver injury.

关键词： Alcoholic liver disease Probiotics Nuclear factor E2-related factor 2(Nrf2) Oxidative stress Short-chain fatty acids

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Bioinspired Hollow Mesoporous Silica Nanoparticles Coating on Titanium Alloy with Hierarchical Structure for Modulating Cellular Functions

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Journal of Bionic Engineering 2024年第3期21卷 1427-1441页

作者： jiaxin zhang He Liu Jincheng Wang Jing Shang Mingwei Xu Xiujie Zhu Chao Xu Haotian Bai Xin Zhao Orthopedic Institute of Jilin Province Orthopedic Medical CenterThe Second Hospital of Jilin UniversityChangchun130041China Key Laboratory of Bionic Engineering(Ministry of Education) Jilin UniversityChangchun130025China Institute of Structured and Architected Materials Liaoning Academy of MaterialsShenyang110167China

3D-printed Porous Titanium Alloy Implants(pTi),owing to their biologically inertness and relatively smooth surface morphology,adversely affect the biological functions of surrounding *** address the challenges,constructing a bioinspired interface that mimics the hierarchical structure of bone tissue can enhance the cellular functions of *** this context,Hollow Mesoporous Silica Nanoparticles(HMSNs),renowned for their unique physicochemical properties and superior biocompatibility,offer a promising direction for this *** this research,the initially synthesized HMSNs were used to construct a“hollow-mesoporous-macroporous”hierarchical bioinspired coating on the pTi surface through the Layer-by-Layer ***,diverse morphologies of coatings were established by adjusting the deposition strategy of PDDA/HMSNs on the pTi surface(pTi-HMSN-2,pTi-HMSN-4,pTi-HMSN-6).A range of techniques were employed to investigate the physicochemical properties and regulation of cellular biological functions of the diverse HMSN coating ***,the pTi-HMSN-4 and pTi-HMSN-6 groups exhibited the uniform coatings,leading to a substantial enhancement in surface roughness and ***,the coating constructed strategy of pTi-HMSN-4 possessed commendable *** on the aforementioned findings,both pTi-HMSN-4 and pTi-HMSN-6 facilitated the adhesion,spreading,and pseudopodia extension of BMSCs,which led to a notable upsurge in the expression levels of vinculin protein in *** analysis indicates that the coating,when PDDA/HMSNs are deposited four times,possesses favorable overall *** research will provide a solid theoretical basis for the translation of HMSN bioinspired coatings for orthopedic implants.

关键词： Hollow mesoporous silica nanoparticles Bioinspired coating Titanium alloy Hierarchical structure Cellular functions

A mitochondria-targeted H_(2)S-activatable fluorogenic probe for tracking hepatic ischemia-reperfusion injury

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Chinese Chemical Letters 2024年第6期35卷 370-375页

作者： Bin Fang Jiaqi Yang Limin Wang Haoqin Li Jiaying Guo jiaxin zhang Qingyuan Guo Bo Peng Kedi Liu Miaomiao Xi Hua Bai Li Fu Lin Li School of Materials Science and Engineering Northwestern Polytechnical UniversityXi’an 710072China Frontiers Science Center for Flexible Electronics Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Key laboratory of Flexible Electronics of Zhejiang Province Ningbo Institute of Northwestern Polytechnical UniversityNingbo 315103China The Institute of Flexible Electronics(IFE Future Technologies)Xiamen UniversityXiamen 361005China Wuhan National Laboratory for Optoelectronics-Advanced Biomedical Imaging Facility Huazhong University of Science and TechnologyWuhan 430074China TANK Medicinal Biology Institute of Xi’an Xi’an 710032China

Hepatic ischemia-reperfusion injury(HIRI)is the cause of postoperative hepatic dysfunction and failure,and even *** an important biological effector molecule,hydrogen sulfide(H_(2)S)of mitochondria as a gasotransmitter that is usually used to protect against acute HIRI ***,the exact relationship between HIRI and mitochondrial H_(2)S remains tangled due to the lack of an effective analytical ***,we have fabricated a mitochondria-targeted H_(2)S-activatable fluorogenic probe(Mito-GW)to explore the stability of mitochondrial H_(2)S and track the changes of mitochondrial H_(2)S during the *** virtue of pyridinium electropositivity and its amphiphilicity,Mito-GW could accumulate in *** goes through an analyte-prompted immolation when reacts with H_(2)S,resulting in the releasing of the fluorophore(GW).Therefore,the extent of Mito-GW conversion to GW can be used to evaluate the changes of mitochondrial H_(2)S level in living cells and *** proof-of-principle,we have used MitoGW to demonstrate the mitochondria H_(2)S-levels increase and then decrease during HIRI in vitro and in *** research highlights the tremendous potential of Mito-GW as a mitochondrial H_(2)S fluorogenic probe in elucidating the pathogenesis of HIRI,providing a powerful tool for promoting future research on hepatology.

关键词： Mitochondria-targeted Bioimaging H2S-activatable Fluorogenic probe Hepatic ischemia-reperfusion injury(HIRI)

Strategies and Economic Benefit Analysis for Productive Landscape of Rape Flower Sea in Cold Regions

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Journal of Northeast Agricultural University(English Edition) 2024年第2期31卷 34-42页

作者： zhang jiaxin Wu Zhiheng Zhu Xuanbo Pan Shengkai Yan Yongqing College of Horticulture and Landscape Architecture Northeast Agricultural UniversityHarbin 150030China

The cold regions are located in high latitudes and cold *** local excellent ornamental plant resources are relatively *** plant species that are suitable for both ornamental and productive benefits of landscape of flower sea construction are also even ***,it is imperative to introduce and screen the plant resources suitable for cold regions to create the landscape of flower *** rape,an oilseed crop,was used as a research object in order to create a productive flower landscape with both ornamental and economic values in cold *** rape flower varieties,Qingza No.5,7,9,and 11,were introduced from Qinghai Hufeng Agricultural Science and Technology Group Co.,*** were planted in the experimental practice base of Northeast Agricultural University in three *** characteristics and seed yield of rape flowers on different sowing dates were *** fuzzy probability method was used to comprehensively evaluate the *** results showed that the rape flowers grew well in Harbin City during the experimental sowing period,which could form a good landscape of flower sea and had a considerable rapeseed *** could be widely used in cold urban and rural areas,such as Harbin *** view of the experimental results,the strategies of creating a productive landscape of rape flower sea were proposed and the economic benefits were *** could change the status quo of a uniform landscape of flower sea in cold regions,help the development of rural tourism,and promote local economic income.

关键词： rape flower sea productive landscape cold region landscape construction economic benefit

紧密栅棒束通道氦氙混合气体流动传热特性数值模拟研究

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核动力工程 2024年第4期45卷 53-60页

作者：张嘉鑫鲍辉丛腾龙顾汉洋上海交通大学核科学与工程学院上海200240 中国核动力研究设计院成都61021

针对氦氙冷却高温气冷堆堆芯设计和分析需求,本研究建立了一套涵盖物性模型、湍流模型与湍流普朗特数模型的氦氙混合气体三维流动传热模型,并基于此模型开展了棒束通道内氦氙混合气体流动传热数值分析,研究几何参数和运行参数对相关特... 详细信息

针对氦氙冷却高温气冷堆堆芯设计和分析需求,本研究建立了一套涵盖物性模型、湍流模型与湍流普朗特数模型的氦氙混合气体三维流动传热模型,并基于此模型开展了棒束通道内氦氙混合气体流动传热数值分析,研究几何参数和运行参数对相关特性的影响规律。结果表明:包壳存在会对紧密栅棒束通道内流动传热带来较大的周向非均匀性,在子通道模拟及整体三维数值模拟中均应考虑包壳导热影响;除包壳外,紧密栅棒束通道内氦氙流动传热则主要受栅径比影响,同一工况下栅径比越大,混合气体对流换热越强烈。

关键词：紧密栅棒束氦氙混合气体流动传热特性

宽带多载波微波光链路的自适应非迭代线性化技术

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光学学报 2024年第12期44卷 205-213页

作者：卢冰陈康侯维刚白一凡张佳昕郭磊重庆邮电大学通信与信息工程学院重庆邮电大学智能通信与网络安全研究院

本文针对宽带多载波微波光子链路（MPL）中产生的带内三阶交调失真（IMD3）和带外互调失真（XMD），给出了相应的非线性失真模型，然后基于失真模型中的XMD和IMD3信号与基频信号符号相反的特性来获取具有闭式解的代价函数，从而在快速... 详细信息

本文针对宽带多载波微波光子链路（MPL）中产生的带内三阶交调失真（IMD3）和带外互调失真（XMD），给出了相应的非线性失真模型，然后基于失真模型中的XMD和IMD3信号与基频信号符号相反的特性来获取具有闭式解的代价函数，从而在快速自适应获取最优线性化系数的同时完成对XMD和IMD3的补偿。与现有的XMD和IMD3补偿方法相比，该方法无需系统和信号的先验参数，无需复杂的训练和迭代优化过程，实用性更好。仿真结果表明，在基于马赫-曾德尔调制器的MPL中传输多音信号时，链路中产生的XMD和IMD3分别被抑制了35 dB和29 dB以上；此外，当传输多载波正交频分复用信号时，信号的误差矢量幅值从8.1%优化到了2.2%。

关键词：微波光子学数字线性化三阶交调失真互调失真

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Acceptor Engineering Produces Ultrafast Nonradiative Decay in NIR-Ⅱ Aza-BODIPY Nanoparticles for Efficient Osteosarcoma Photothermal Therapy via Concurrent Apoptosis and Pyroptosis

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Research 2024年第1期2024卷 625-635页

作者： Zhenxiong Shi Hua Bai jiaxing Wu Xiaofei Miao Jia Gao Xianning Xu Yi Liu Jiamin Jiang Jiaqi Yang jiaxin zhang Tao Shao Bo Peng Huili Ma Dan Zhu Guojing Chen Wenbo Hu Lin Li Wei Huang Frontiers Science Center for Flexible Electronics Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Key Laboratory for Organic Electronics and Information Displays&Institute of Advanced Materials(IAM) Nanjing University of Posts&TelecommunicationsNanjing 210023China Key Laboratory of Flexible Electronics(KLOFE)and IAM Nanjing Tech UniversityNanjing 211800China Britton Chance Center for Biomedical Photonics-MoE Key Laboratory for Biomedical Photonics Wuhan National Laboratory for Optoelectronics-Advanced Biomedical Imaging FacilityHuazhong University of Science and TechnologyWuhan 430074China Department of Orthopedics Xijing HospitalThe Fourth Military Medical UniversityXi’an 710032China The Institute of Flexible Electronics(IFE Future Technologies)Xiamen UniversityXiamen 361005China

Small-molecule photothermal agents(PTAs)with intense second near-infrared(NIR-Ⅱ,1,000 to 1,700 nm)absorption and high photothermal conversion efficiencies(PCEs)are promising candidates for treating deep-seated tumors such as *** date,the development of small-molecule NIR-Ⅱ PTAs has largely relied on fabricating donor–acceptor–donor(D–A–D/D′)structures and limited success has been ***,through acceptor engineering,a donor–acceptor–acceptor(D–A–A′)-structured NIR-Ⅱ aza-boron-dipyrromethene(aza-BODIPY)PTA(SW8)was readily developed for the 1,064-nm laser-mediated phototheranostic treatment of *** the donor groups to acceptor groups produced remarkable red-shifts of absorption maximums from first near-infrared(NIR-Ⅰ)regions(~808 nm)to NIR-Ⅱ ones(~1,064 nm)for aza-BODIPYs(SW1 to SW8).Furthermore,SW8 self-assembled into nanoparticles(SW8@NPs)with intense NIR-Ⅱ absorption and an ultrahigh PCE(75%,1,064 nm).This ultrahigh PCE primarily originated from an additional nonradiative decay pathway,which showed a 100-fold enhanced decay rate compared to that shown by conventional pathways such as internal conversion and vibrational ***,SW8@NPs performed highly efficient 1,064-nm laser-mediated NIR-Ⅱ photothermal therapy of osteosarcoma via concurrent apoptosis and *** work not only illustrates a remote approach for treating deep-seated tumors with high spatiotemporal control but also provides a new strategy for building high-performance small-molecule NIR-Ⅱ PTAs.

关键词： donor BODIPY intense

Burkholderia ***3对粪臭素的响应及下游代谢基因

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应用与环境生物学报 2024年第3期30卷 579-585页

作者：李玉洁张佳鑫王彩红马桥大连海事大学环境科学与工程学院大连116026

粪臭素是一种具有强烈粪臭味的氮杂环芳烃污染物,广泛存在于动物肠道、粪便、垃圾填埋场和海洋等环境介质中,较为稳定且难以降解.以Burkholderia ***3为研究对象,系统研究菌株在粪臭素压力下的生理生化响应,并利用RT-qPCR和异源表达技... 详细信息

粪臭素是一种具有强烈粪臭味的氮杂环芳烃污染物,广泛存在于动物肠道、粪便、垃圾填埋场和海洋等环境介质中,较为稳定且难以降解.以Burkholderia ***3为研究对象,系统研究菌株在粪臭素压力下的生理生化响应,并利用RT-qPCR和异源表达技术探究下游降解功能基因.结果显示,粪臭素对Burkholderia ***3最小抑制浓度为1.5mmol/L;粪臭素促进菌膜形成和提高菌株表面疏水性,且呈剂量依赖性.氧化应激实验表明粪臭素提高Burkholderia ***3的超氧化物歧化酶和过氧化氢酶活性,抑制菌株脂质过氧化(丙二醛)以及还原型谷胱甘肽含量.结合前期组学分析推测邻苯二酚1,2-双加氧酶基因(DCN14_04105)可能为下游代谢关键基因,RT-qPCR实验表明该基因在粪臭素压力下上调3.70倍.将该基因在大肠杆菌中表达并获得纯酶,结果表明该酶最适pH为8.5,最适温度为30℃,Zn^(2+)、Co^(2+)、Cd^(2+)、Se4+、Sn^(2+)、Ca^(2+)对其具有抑制作用,Km值为25.98μmol/L,kcat值为10.70 s-1.本研究表明粪臭素影响了Burkholderia ***3菌株的生理生化性能,菌株代谢粪臭素中心代谢途径为邻苯二酚1,2-双加氧酶途径.该结果可为粪臭素的高效降解提供新的微生物资源,也为粪臭素的功能研究提供参考.(图7表1参30)

关键词：粪臭素伯克霍尔德菌功能响应生物降解邻苯二酚1 2-双加氧酶

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