检索结果-南通市图书馆

Revolutionizing breast cancer detection:Advances in fluorescent probe technology

在线全文

学校读者我要写书评

暂无评论

Nano Research 2025年第1期18卷 653-674页

作者： Qian Gao Lin Tang Jun zhan Yiyuan Xue Feng Luo State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases West China Hospital of StomatologySichuan UniversityChengdu 610041China Emergency Obstetrics and Gynecology West China Second University HospitalSichuan UniversityChengdu 610041China Department of Obstetrics and Gynecology West China Second University HospitalSichuan UniversityChengdu 610041China Department of Prosthodontics West China School of StomatologySichuan UniversityChengdu 610041China

With the increasing incidence of breast cancer globally,there is an urgent demand for enhanced diagnostic and therapeutic *** comprehensive review explores advancements in fluorescent probe technology for breast cancer imaging and early *** probes offer unparalleled sensitivity and specificity in detecting cancer biomarkers,enabling early diagnosis and delineation of tumor margins during *** categorize these probes into molecular,nano,ratiometric,the second near-infrared window(NIR-II),and multifunctional varieties,each with unique capabilities for targeting specific cancer *** review highlights recent innovations in probe design,emphasizing their applications in pathogenesis studies,drug development,precision medicine,and fluorescence-guided *** their promising clinical potential,challenges such as safety,biomarker targeting accuracy,system compatibility,and clinical translation *** these hurdles is crucial for the integration of fluorescent probes into standard cancer care,aiming to improve treatment outcomes and patient quality of life.

关键词： breast cancer fluorescent probes imaging early diagnosis biomarker

Pricing the spare bandwidth: towards maximizing data center's profit

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2016年第10期59卷 50-59页

作者： Yong zhan du XU Hongfang YU School of Communication & Information Engineering University of Electronic Science and Technology of China

To provide tenants with predictable network performance, tenants are allowed to purchase specified amount of data center network(DCN) resources(e.g., bandwidth). Then, data center will reserve the purchased resources for the corresponding tenants. Meanwhile, some DCNs are work conserving, which means that the spare bandwidth will be fairly shared by all active tenants. Even though the amount of the spare bandwidth is stochastic and uncertain, DCN providers are not likely to give away it for free. Thus, data center with work conserving may impose extra payment on tenants for using the spare bandwidth. In this paper, we propose a suitable tariff to charge for the usages of DCN resources, which includes a bill for the usage of the spare bandwidth. Through theoretical analysis and simulation, we demonstrate that our tariff can incentivize tenants to adjust their purchases of bandwidths, which can lead to the improvement of data center's profit by 27.4%without impairing the social welfare.

关键词： spare bandwidth data center network(DCN) bandwidth reservation work conserving pricing/tariff

Immunological Responses to the Combination of EBNA1 and LMP2 in Mice

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2019年第5期32卷 380-382页

作者： du hai Jun TONG Yan Yan WANG zhan zhanG Li Xia ZENG Yi State Key Laboratory for Infectious Disease Prevention and Control National Institute of Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China College of Life Science and Bioengineering Beijing University of TechnologyBeijing 100124China

Epstein-Barr virus (EBV) infection is closely associated with nasopharyngeal carcinoma (NPC)and considered one of the major risk factors[1]. A limited number of viral proteins, such as latent membrane proteins (LMP1, LMP2) and EB nuclear antigen1 (EBNA1), are expressed in NPC cells[2].Recognition epitopes for CD8+and CD4+T cells were included in the LMP2 antigen and EBNA1 C-terminal region (amino acid No. 380-641), respectively[3,4].Both CD4+and CD8+memory T-cell responses were efficiently reactivated by EBNA1 and LMP2[5;6].

关键词： Immunological Responses EBNA1 LMP2

Multi-performance evaluation of high-throughput accelerated corrosion test for high-strength low-alloy 921A steel

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2024年第5期31卷 1260-1278页

作者： Cong-cong du Ming-hua Qin zhan-fang Wu Dong-ling Li Lei Zhao Xiang-yang Li hai-zhou Wang Beijing Advanced Innovation Center for Materials Genome Engineering National Center for Materials Service SafetyUniversity of Science and Technology BeijingBeijing100083China China Iron and Steel Research Institute Group Co. Ltd.Beijing100081China Beijing Advanced Innovation Center for Materials Genome Engineering Central Iron and Steel Research InstituteBeijing100081China

The corrosion behavior of high-strength low-alloy 921A steel in a simulated marine atmospheric environment was studied using a high-throughput experimental *** corrosion behavior,corrosion morphology,and corrosion products of 921A steels were analyzed using various techniques,including corrosion mass loss method,polarization curve,white-light interferometry,scanning electron microscopy,energy-dispersive spectrometry,microbeam X-ray fluorescence spectrometry,X-ray diffraction technique,and X-ray photoelectron *** test results indicated that 921A steel exhibits better corrosion resistance than Q450NQR1 steel in simulated harsh atmospheric environments,as evidenced by a lower corrosion mass loss rate throughout the corrosion *** corrosion products of both steels consisted ofα-FeOOH,Fe_(3)O_(4),andγ-FeOOH,withα-FeOOH being more prevalent in the rust layer of 921A steel than in Q450NQR1 *** inner rust layer of 921A steel also exhibited an appositional enrichment region of Cr,Ni,Mo,and V,leading to its superior corrosion resistance compared to that of Q450NQR1 *** efficacy of high-throughput accelerated corrosion experimental methods was highlighted for evaluating the corrosion resistance of steel materials in harsh environmental *** findings suggest that 921A steel exhibits better corrosion resistance compared to Q450NQR1 steel and has the potential to be more suitable in harsh marine atmospheric *** characterization of the rust layer structures and composition reveals the parallel enrichment of certain elements in the inner rust layer of 921A steel,which enhances its corrosion resistance.

关键词： Atmospheric corrosion High-throughput experimental method High-strength low-alloy steel Corrosion characteristics Rust layer Element enrichment

The relationships of solar flares with both sunspot and geomagnetic activity

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2012年第4期12卷 400-410页

作者： zhan-Le du Hua-Ning Wang Key Laboratory of Solar Activity National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100012China

The relationships between solar flare parameters （total importance, time duration, flare index, and flux） and sunspot activity （R z ） as well as those between geomagnetic activity （aa index） and the flare parameters can be well described by an integral response model with the response time scales of about 8 and 13 months, respectively. Compared with linear relationships, the correlation coefficients of the flare parameters with R z , of aa with the flare parameters, and of aa with R z based on this model have increased about 6%, 17%, and 47% on average, respectively. The time delays between the flare parameters with respect to R z , aa to the flare parameters, and aa to R z at their peaks in a solar cycle can be predicted in part by this model （82%, 47%, and 78%, respectively）. These results may be further improved when using a cosine filter with a wider window. It implies that solar flares are related to the accumulation of solar magnetic energy in the past through a time decay factor. The above results may help us to understand the mechanism of solar flares and to improve the prediction of the solar flares.

关键词： Sun: activity -- Sun: sunspots -- Sun: flares -- geomagnetic activity

Constitutive relation of weakly anisotropic polycrystal with microstructure and initial stress

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 2007年第2期23卷 183-198页

作者： Mojia Huang Hua zhan Xiuqiao Lin hai Tang Institute of Engineering Mechanics Nanchang UniversityNanchang 330029 China

Man （Nondestr Test Eval 15：191-214, 1999） derived the constitutive relation of a weakly-textured orthorhombic aggregate of cubic crystallites with effects of microstructure and initial stress. In this paper, a computational expression on the integration ∫SO（3） Q^× D^1m0dg is given. Then, by means of the computational expression, the general constitutive relation of a weakly-textured anisotropic polycrystal with the consideration of microstructure and initial stress is derived. As special cases of our general constitutive relation, two constitutive relations are given for an isotropic polycrystal and a weakly-textured anisotropic aggregate of cubic crystallites. The acoustoelastic tensor of the reference cubic crystal is derived to determine the material constants of the polycrystal. Two examples are given for understanding the physical meaning of the texture coefficients and the constitutive relations.

关键词： Generalconstitutive relation of weakly-textured polycrystal .Microstructure Initial stress .Cubic crystallites

The prediction method of similar cycles

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2011年第12期11卷 1482-1492页

作者： zhan-Le du Hua-Ning Wang Key Laboratory of Solar Activity National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China

The concept of degree of similarity （η）, is proposed to quantitatively describe the similarity of a parameter （e.g. the maximum amplitude Rmax） of a solar cycle relative to a referenced one, and the prediction method of similar cycles is further developed. For two parameters, the solar minimum （Rmin） and rising rate （βa）, which can be directly measured a few months after the minimum, a synthesis degree of similarity （ηs） is defined as the weighted-average of the η values around Rmin and βa, with the weights given by the coefficients of determination of Rmax with Rmin and βa, respectively. The monthly values of the whole referenced cycle can be predicted by averaging the corresponding values in the most similar cycles with the weights given by the ηs values. As an application, Cycle 24 is predicted to peak around January 2013 i8 （month） with a size of about Rmax = 84 ± 17 and to end around September 2019.

关键词： Sun: activity -- Sun: general -- sunspots

Does a low solar cycle minimum hint at a weak upcoming cycle?

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2010年第10期10卷 950-955页

作者： zhan-Le du Hua-Ning Wang Key Laboratory of Solar Activity National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China

The maximum amplitude （Rm） of a solar cycle, in the term of mean sunspot numbers, is well-known to be positively correlated with the preceding minimum （Rmin）. So far as the long term trend is concerned, a low level of Rmin tends to be followed by a weak Rm, and vice versa. We found that the evidence is insufficient to infer a very weak Cycle 24 from the very low Rmin in the preceding cycle. This is concluded by analyzing the correlation in the temporal variations of parameters for two successive cycles.

关键词： Sun activity -- Sun general -- sunspots

中山大学科技期刊出版史略(1866—2024)

在线全文

学校读者我要写书评

暂无评论

中山大学学报（自然科学版）（中英文） 2025年第1期64卷 1-27页

作者：张冰詹拔群中山大学学报编辑部广东广州510275 中山大学期刊管理中心广东广州510275

本文力图较为完整地展现中山大学100多年的科技期刊出版历史全貌,在明晰中山大学办学源流的基础上将其前身各校的科技期刊出版情况纳入梳理,整理统计出中山大学及其前身各校在正式建校前(1866—1923年)出版科技期刊25种、建校后的民国时... 详细信息

本文力图较为完整地展现中山大学100多年的科技期刊出版历史全貌,在明晰中山大学办学源流的基础上将其前身各校的科技期刊出版情况纳入梳理,整理统计出中山大学及其前身各校在正式建校前(1866—1923年)出版科技期刊25种、建校后的民国时期(1924—1948年)出版科技期刊87种,共和国时期(1949—2024年)出版科技期刊60种,共计172种,并对代表性刊物进行简要介绍。中山大学的科技期刊出版以医学类期刊的贡献最为突出,其影响一直延续至今。这些科技期刊从科研学术角度记录了中山大学的学科发展历史,同时为中国近代科学技术的传播和发展作出了重要的贡献。

关键词：中山大学科技期刊出版史校史