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敦煌画中的回鹘神祇——对P.4518(24)纸本的再讨论

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兰州大学学报（社会科学版） 2020年第6期48卷 140-153页

作者：周晓萍兰州大学敦煌学研究所甘肃兰州730000

敦煌P.4518(24)绘画中的主体人物,一直以来被学者考证认为是粟特祆教神祇。本文在前贤研究的基础之上首先从图像中主体人物衣冠服饰及犬、狼在图像上的表现入手,论证了该图像具有的回鹘民族的文化特征。其次,通过图文互证的方式分析认为... 详细信息

敦煌P.4518(24)绘画中的主体人物,一直以来被学者考证认为是粟特祆教神祇。本文在前贤研究的基础之上首先从图像中主体人物衣冠服饰及犬、狼在图像上的表现入手,论证了该图像具有的回鹘民族的文化特征。其次,通过图文互证的方式分析认为,图像中左像为吉祥天女,右像为四臂观音。两尊像的成因基于唐宋间敦煌佛教的密教化、民间化,体现了回鹘佛教信仰的显密结合及对当地传统民间信仰图式的纳入,表现了四臂观音手持日月、蛇蝎的造像特征。根据回鹘多宗教信仰,多文化融合的民族特性,认为10世纪甘州回鹘将不同信仰的崇拜对象融为一体,创造了以回鹘天公主为特征的佛教吉祥天女及四臂观音的形象。

关键词：回鹘犬狼吉祥天女四臂观音

Effect of Down-regulation of MMP-2 by Quercetin on the Migration and Invasion of Uterine Fibroids Cells through the cAMP Signaling Pathway

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Chinese Journal of Biomedical Engineering 2024年第2期33卷 54-61页

作者： LIN Shu-ping ZOU xiao-fen Longyan First Affiliated Hospital of Fujian Medical University

Objective: To investigate the effect of down-regulation of matrix metalloproteinase-2(MMP-2) by down-regulating the cyclic adenosine monophosphate(cAMP) signaling pathway on the migration and invasion of uterine fibroids ***: A total of 65 female SD rats were randomly divided into five groups after being adaptively fed for 7 d. Except for the blank group, the remaining four groups of rats were injected with 0.05 mg/(100 g·d) estradiol benzoate and 0.5 mg/(100g·d) progesterone into the muscle to establish a uterine fibroids rat model. After successful modeling, the blank group and model group were given 200 mg/(kg·d) physiological saline by gavage,the low-dose group was given 100 mg/(kg·d) mifepristone by gavage, the medium-dose group was given 200 mg/(kg·d) mifepristone by gavage, and the high-dose group was given 300 mg/(kg·d) mifepristone by gavage. After continuous gavage treatment for 21 d,serum and uterine tissues were collected from rats to observe and compare the expression levels of MMP-2 mRNA, TIMP-2 mRNA, estradiol(E2), cAMP signaling pathway related proteins, and the migration and invasive ability of uterine fibroids cells in the five groups of rats. Results: The expression levels of MMP-2 mRNA and E2in the high-dose group were lower than those in the low-dose group and the medium-dose group, and the expression level of TIMP-2 mRNA was higher than that in the low-dose group and the medium-dose group(P<0.05). The number of cell migration in a single visual field of rats in the high-dose group was lower than that in the low-dose group and the medium-dose group(P<0.05). The number of cell invasion in a single visual field of rats in the high-dose group was lower than that in the low-dose group and the medium-dose group(P<0.05). The mRNA expression levels of cAMP, PDE and PK in the high-dose group were higher than those in the low-dose group, and the mRNA expression levels of AC in the high-dose group were lower than those in the low-dose group(P<0.

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Al-Mg_2Si复合涂层在3.5%NaCl水溶液中的腐蚀磨损性能研究

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表面技术 2018年第4期47卷 260-266页

作者：范春龙威周小平湖北工业大学绿色轻工材料湖北省重点实验室武汉430068

目的研究Al-Mg_2Si复合涂层在3.5%NaCl溶液中的腐蚀-磨损性能。方法用电化学工作站(CHI660E)、腐蚀-磨损试验机测试试样的电化学行为及实时监测在3.5%NaCl溶液中的开路电位、摩擦系数和干摩擦性能,并采用扫描电镜(SEM)、超景深三维显微... 详细信息

目的研究Al-Mg_2Si复合涂层在3.5%NaCl溶液中的腐蚀-磨损性能。方法用电化学工作站(CHI660E)、腐蚀-磨损试验机测试试样的电化学行为及实时监测在3.5%NaCl溶液中的开路电位、摩擦系数和干摩擦性能,并采用扫描电镜(SEM)、超景深三维显微镜对磨痕特征进行表征。结果镁合金自腐蚀电位为-1.4888V,腐蚀电流密度为2.817×10^(-3) A/cm^2。与镁合金基体相比,Al-Mg_2Si复合涂层的自腐蚀电位正移了0.5288V,腐蚀电流密度降低了3个数量级。腐蚀磨损过程中,Al-Mg_2Si复合涂层的开路电位(OCP)为-0.9202 V,比镁合金基体高0.5713 V。干摩擦过程中,复合涂层的稳定摩擦系数为0.28,比镁合金低0.07。复合涂层干、湿磨损率相差44.72×10^(-4) mm^3/(N?mm),其值是镁合金基体干、湿磨损率相差值的0.52倍,且均远远大于各自纯机械磨损率。结论在腐蚀磨损过程中,腐蚀是造成磨蚀损失的主要原因,且Al-Mg_2Si复合涂层的耐磨蚀性能优于镁合金基体。

关键词： AZ31B镁合金 Al-Mg2Si复合涂层腐蚀磨损干摩擦摩擦系数

Al含量对Al-Mg_2Si复合涂层耐蚀耐磨性能的影响

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表面技术 2018年第2期47卷 225-230页

作者：范春龙威周小平湖北工业大学绿色轻工材料湖北省重点实验室武汉430068

目的在AZ31B镁合金表面火焰喷涂制备Al-Mg_2Si复合涂层,研究其耐腐蚀和耐磨性能。方法用SEM、电化学测试仪、高速往复摩擦磨损测试仪和超景深三维显微镜检测分析不同成分配比的Al-Mg_2Si复合涂层的耐腐蚀和摩擦磨损性能。结果 Al-Mg_2S... 详细信息

目的在AZ31B镁合金表面火焰喷涂制备Al-Mg_2Si复合涂层,研究其耐腐蚀和耐磨性能。方法用SEM、电化学测试仪、高速往复摩擦磨损测试仪和超景深三维显微镜检测分析不同成分配比的Al-Mg_2Si复合涂层的耐腐蚀和摩擦磨损性能。结果 Al-Mg_2Si复合涂层的电位较AZ31B镁合金基体正,且Al含量越少,电位正移越明显。Al(20%)-Mg_2Si复合涂层的自腐蚀电位正移得最多,正移了0.5288 V;自腐蚀电流密度最小,为3.298×10-6 A/cm2。Al加入量越少,复合涂层的磨损率和摩擦系数越小,当Al质量分数为20%时,两者均达到最小值,分别为2.48×10-4 mm3/(N·mm)和0.25。结论 Al含量越少,Al-Mg_2Si复合涂层的耐蚀和耐磨性能越好。

关键词： AZ31B镁合金火焰喷涂 Al-Mg2Si复合涂层耐蚀性耐磨性

AZ31B镁合金表面火焰喷涂Al-Mg_2Si涂层的耐腐蚀性能

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中国表面工程 2017年第2期30卷 113-118页

作者：范春龙威周小平湖北工业大学绿色轻工材料湖北省重点实验室武汉430068

为提高AZ31B镁合金表面的耐腐蚀性能,用火焰喷涂方法在镁合金表面制备Al-Mg_2Si复合涂层。采用XRD、SEM和EDS分析涂层的物相组成、微观组织及元素分布;通过电化学试验测试样品在3.5%NaCl溶液中的腐蚀电位、腐蚀电流密度;通过3.5%NaCl溶... 详细信息

为提高AZ31B镁合金表面的耐腐蚀性能,用火焰喷涂方法在镁合金表面制备Al-Mg_2Si复合涂层。采用XRD、SEM和EDS分析涂层的物相组成、微观组织及元素分布;通过电化学试验测试样品在3.5%NaCl溶液中的腐蚀电位、腐蚀电流密度;通过3.5%NaCl溶液浸泡试验测试样品的腐蚀速率;并测试涂层的显微硬度。结果表明:涂层中的主要物相有Mg_2Si、Al,组织比较致密,元素分布均匀。Tafel极化曲线测试表明,Al-Mg_2Si涂层样品与AZ31B镁合金样品相比腐蚀电位从-1.489 V正移到-1.366 V,腐蚀电流密度从2.817×10^(-3) A/cm^2降低到1.198×10^(-3) A/cm^2。浸泡试验结果表明,喷涂Al-Mg_2Si的镁合金的腐蚀速率明显低于没有喷涂的镁合金。显微硬度测试表明,涂层的显微硬度集中分布在259~308 HV0.05之间,镁合金为50~60 HV0.05。因此在AZ31B镁合金表面火焰喷涂Al-Mg_2Si涂层可以提高其耐腐蚀性能,表面硬度显著提高。

关键词： AZ31B镁合金火焰喷涂 Al-Mg2Si涂层耐腐蚀性能

载荷及摩擦频率对Al-Mg_2Si复合涂层摩擦性能的影响

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表面技术 2018年第3期47卷 159-164页

作者：范春龙威周小平湖北工业大学绿色轻工材料湖北省重点实验室武汉430068

目的研究载荷及摩擦频率对Al-Mg_2Si复合涂层摩擦磨损性能的影响。方法用高速往复摩擦磨损测试仪考察了不同载荷及摩擦频率下的Al-Mg_2Si复合涂层的摩擦系数,并用SEM和超景深三维显微镜检测分析磨痕的表面形貌、磨痕深度和体积,对比分... 详细信息

目的研究载荷及摩擦频率对Al-Mg_2Si复合涂层摩擦磨损性能的影响。方法用高速往复摩擦磨损测试仪考察了不同载荷及摩擦频率下的Al-Mg_2Si复合涂层的摩擦系数,并用SEM和超景深三维显微镜检测分析磨痕的表面形貌、磨痕深度和体积,对比分析载荷及摩擦频率的影响。结果载荷一定时,随着摩擦频率的增大,摩擦系数呈下降趋势,体积磨损率呈上升趋势。频率为3 Hz时,摩擦系数最小,为0.50;体积磨损率最大,为166.08×10^(-4) mm^3/(N·mm)。频率从1 Hz增至3 Hz时,摩擦系数减少了0.65,体积磨损率增加了3.1倍。频率一定时,随着载荷的增加,摩擦系数和体积磨损率均呈增加趋势。载荷为15 N时,摩擦系数和体积磨损率最大,分别为0.93和126.27×10^(-4) mm^3/(N·mm)。载荷从5 N增至15 N时,摩擦系数增加了0.27,体积磨损率增加了0.4倍。结论与载荷相比,摩擦频率对Al-Mg_2Si复合涂层摩擦性能的影响更大。

关键词： Al-Mg2Si复合涂层摩擦频率载荷摩擦磨损

基于论域和量值二类错误逻辑变量求解的识别对象状态转化及其决策应用研究

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数学的实践与认识 2017年第5期47卷 198-207页

作者：周小平广东轻工职业技术学院教务处广东广州510300

研究了空间事物特征为确定常量的条件下,论域和量值参数为变量且未知时,错误识别对象状态的转化.研究发现,当对象识别状态的论域和量值都为Ⅱ类时,可以采用错误矩阵一类4集合方程A_s∨X_(qg)■B_g构建二元置换变换错误矩阵集合方程,将... 详细信息

研究了空间事物特征为确定常量的条件下,论域和量值参数为变量且未知时,错误识别对象状态的转化.研究发现,当对象识别状态的论域和量值都为Ⅱ类时,可以采用错误矩阵一类4集合方程A_s∨X_(qg)■B_g构建二元置换变换错误矩阵集合方程,将错误的对象识别状态转化为应该状态.最后,通过生产决策的实例说明其实际决策应用价值.

关键词：论域量值错误逻辑变量对象状态转化

Influence of Acupuncture plus LONG＇s Manual Manipulations on Functional Improvement in Lumbar Intervertebral Disc Protrusion

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Journal of Acupuncture and Tuina Science 2010年第6期8卷 375-379页

作者：周晓平黄存军 Department of Chinese Medicine Liwan Hospital of Guangzhou Medical College Guangdong 510170 R R. China

Objective： To observe the effect of acupuncture plus LONG＇s manual manipulations on the functional improvement of the patients with lumbar intervertebral disc protrusion. Methods： 60 cases of the patients were randomly divided into a observation group and a control group, 30 cases in each group. The observation group was treated with acupuncture plus LONG＇s manual manipulations, and the control group was treated with single acupuncture. The functions of the lumber vertebrae were processed in accordance with the assessment system of Japanese Orthopedic Association （JOA）, and the therapeutic effects were assessed by Visual Analog Scale （VAS）. Results： After the treatments, the differences in JOA and improvement indexes were statistically significant （P〈0.05） between the two groups. VAS was decreased much remarkably in the observation group （P〈0.01） than before the treatments and decreased remarkably in the control group （P〈0.05） than before the treatments. There was a remarkable difference in VAS between the two groups after the treatments （P〈0.05）. Conclusion： Acupuncture plus LONG＇s manual manipulations are better than single acupuncture in improving the functions of the patients with lumbar intervertebral disc protrusion.

关键词： Acupuncture Therapy Tuina Massage Intervertebral Disc Displacement Low Back Pain

MdbHLH162 connects the gibberellin and jasmonic acid signals to regulate anthocyanin biosynthesis in apple

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Journal of Integrative Plant Biology 2024年第2期66卷 265-284页

作者： Jian-ping An Rui-Rui Xu xiao-Na Wang xiao-Wei Zhang Chun-Xiang You Yuepeng Han Apple technology innovation center of Shandong Province College of Horticulture Science and EngineeringShandong Agricultural UniversityTai-An 271018China CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture Wuhan Botanical GardenHubei Hongshan LaboratoryThe Innovative Academy of Seed Design of Chinese Academy of SciencesWuhan 430074China College of Biology and Oceanography Weifang UniversityWeifang 261061China

Anthocyanins are secondary metabolites induced by environmental stimuli and developmental *** positive regulators of anthocyanin biosynthesis have been reported,whereas the anthocyanin repressors have been *** the signal transduction pathways of gibberellin(GA)and jasmonic acid(JA)and their regulation of anthocyanin biosynthesis have been investigated,the cross-talk between GA and JA and the antagonistic mechanism of regulating anthocyanin biosynthesis remain to be *** this study,we identified the anthocyanin repressor MdbHLH162 in apple and revealed its molecular mechanism of regulating anthocyanin biosynthesis by integrating the GA and JA ***162 exerted passive repression by interacting with MdbHLH3 and MdbHLH33,which are two recognized positive regulators of anthocyanin ***162 negatively regulated anthocyanin biosynthesis by disrupting the formation of the anthocyanin-activated MdMYB1-MdbHLH3/33complexes and weakening transcriptional activation of the anthocyanin biosynthetic genes MdDFR and MdUF3GT by MdbHLH3 and *** GA repressor MdRGL2a antagonized MdbHLH162-mediated inhibition of anthocyanins by sequestering MdbHLH162 from the MdbHLH162-MdbHLH3/33 *** JA repressors MdJAZ1 and MdJAZ2 interfered with the antagonistic regulation of MdbHLH162 by MdRGL2a by titrating the formation of the MdRGL2a-MdbHLH162 *** findings reveal that MdbHLH162 integrates the GA and JA signals to negatively regulate anthocyanin *** study provides new information for discovering more anthocyanin biosynthesis repressors and explores the cross-talk between hormone signals.

关键词： anthocyanin biosynthesis bHLH transcription factor gibberellin jasmonic acid regulatory network transcriptional regulation