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China Communications 2024年第3期21卷 205-216页

作者： zhang Yue Zheng fuchun Luo Jingjing School of Electronic and Information Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China

Due to the limited uplink capability in heterogeneousnetworks (HetNets), the decoupled uplinkand downlink access (DUDA) mode has recently beenproposed to improve the uplink performance. In thispaper, the random discontinuous transmission (DTX)at user equipment (UE) is adopted to reduce the interferencecorrelation across different time slots. By utilizingstochastic geometry, we analytically derive themean local delay and energy efficiency (EE) of an uplinkHetNet with UE random DTX scheme under theDUDA mode. These expressions are further approximatedas closed forms under reasonable *** results reveal that under the DUDA mode, there isan optimal EE with respect to mute probability underthe finite local delay constraint. In addition, with thesame finite mean local delay as under the coupled uplinkand downlink access (CUDA) mode, the HetNetsunder the DUDA mode can achieve a higher EE witha lower mute probability.

关键词： decoupled uplink and downlink access(DUDA) heterogeneous networks(HetNets) random discontinuous transmission(DTX) stochastic geometry

Application of Opening and Closing Morphology in Deep Learning-Based Brain Image Registration

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Journal of Beijing Institute of Technology 2023年第5期32卷 609-618页

作者： Yue Yang Shiyu Liu Shunbo Hu Lintao zhang Jitao Li Meng Li fuchun zhang School of Information Science and Engineering Linyi UniversityShandong Linyi 276000China

In order to improve the registration accuracy of brain magnetic resonance images(MRI),some deep learning registration methods use segmentation images for training ***-ever,the segmentation values are constant for each label,which leads to the gradient variation con-centrating on the ***,the dense deformation field(DDF)is gathered on the boundary and there even appears folding *** order to fully leverage the label information,the morphological opening and closing information maps are introduced to enlarge the non-zero gradi-ent regions and improve the accuracy of DDF *** opening information maps supervise the registration model to focus on smaller,narrow brain *** closing information maps supervise the registration model to pay more attention to the complex boundary ***,opening and closing morphology networks(OC_Net)are designed to automatically generate open-ing and closing information maps to realize the end-to-end training ***,a new registra-tion architecture,VM_(seg+oc),is proposed by combining OC_Net and *** results show that the registration accuracy of VM_(seg+oc) is significantly improved on LPBA40 and OASIS1 ***,VM_(seg+oc) can well improve registration accuracy in smaller brain regions and narrow regions.

关键词： three dimensional(3D)medical image registration deep learning opening operation closing operation morphology

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基于小波分析的输电线路单端故障定位方法

电子设计工程 2024年第13期32卷 135-139页

作者：郑武略张富春张鑫袁文俊王宁中国南方电网有限责任公司超高压输电公司广东广州510000

为精准判别输电线路单端故障的位置,提出基于小波分析的输电线路单端故障定位方法。联合零序电压与故障绕组系数,求解输电转矩指标的取值范围,完成对单端故障暂态特征量的计算。分别从连续小波变换、离散小波变换两方面来完善小波分析理... 详细信息

为精准判别输电线路单端故障的位置,提出基于小波分析的输电线路单端故障定位方法。联合零序电压与故障绕组系数,求解输电转矩指标的取值范围,完成对单端故障暂态特征量的计算。分别从连续小波变换、离散小波变换两方面来完善小波分析理论,获取故障暂态特征量指标的实际取值范围,并以此为基础,确定暂态定位参数的具体取值结果,实现对输电线路单端故障行为的全局定位。实验结果表明,小波分析理论作用下,单端故障节点处最大电压检测差值为5 V、最大电流检测差值为0.1 A,误差较小,符合精准判别输电线路故障的应用需求。

关键词：小波分析输电线路单端故障定位零序电压绕组系数输电转矩

胃动力、精神心理因素与老年胃食管反流病的相关性研究

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中国卫生标准管理 2024年第13期15卷 89-93页

作者：陈嘉琳张富春曾庆新福建省老年医院消化内科福建福州350009

目的探讨胃动力与精神心理因素在老年胃食管反流病(gastroesophageal reflux disease,GERD)发病中的作用。方法选取福建省老年医院2020年1月—2022年12月收治的180例纳入符合GERD诊断标准的患者,将纳入研究人群根据年龄是否≥60岁分为... 详细信息

目的探讨胃动力与精神心理因素在老年胃食管反流病(gastroesophageal reflux disease,GERD)发病中的作用。方法选取福建省老年医院2020年1月—2022年12月收治的180例纳入符合GERD诊断标准的患者,将纳入研究人群根据年龄是否≥60岁分为老年组(n=96)与非老年组(n=84)。比较老年组与非老年组反流性疾病问卷量表(reflux disease questionnaire,RDQ)、汉密尔顿抑郁量表(Hamilton depression scale,HAMD)、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)评分以及胃电图情况;在老年组中,将合并焦虑或抑郁的患者随机分为4组,分别进行常规质子泵抑制剂(proton pump inhibitor,PPI)单药治疗、PPI+伊托必利、PPI+氟哌噻吨美利曲辛片、PPI+伊托必利+氟哌噻吨美利曲辛片治疗,并比较治疗前后胃电图情况、胃肠激素(胃动素、瘦素)水平、HAMD和HAMA评分、RDQ评分。结果非老年组胃电图波形平均频率、波形平均幅值、HAMD、HAMA评分及RDQ评分分别为(2.51±0.46)cpm、(173.27±32.76)μV、(6.75±2.90)分、(7.22±2.90)分、(19.25±4.29)分,老年组胃电图波形平均频率、波形平均幅值、HAMD、HAMA评分及RDQ评分分别为(1.76±0.35)cpm、(60.81±24.40)μV、(14.97±6.83)分、(12.48±6.65)分、(18.92±3.94),老年组与非老年组RDQ值比较,差异无统计学意义(P>0.05);但老年组的HAMD和HAMA分值高于非老年组,胃动力低于非老年组(P<0.05)。老年组中焦虑、抑郁患者治疗后胃动力、胃肠激素(胃动素、瘦素)水平、HAMD、HAMA、RDQ评分均较治疗前有改善(P<0.05);PPI+伊托必利组、PPI+氟哌噻吨美利曲辛片组均较PPI单药组有显著改善,而PPI+伊托必利+氟哌噻吨美利曲辛片组在4组中改善最明显(P<0.05)。结论除了酸暴露之外,胃动力及精神心理因素可能是GERD发病的重要因素之一。

关键词：胃食管反流病胃动力焦虑抑郁精神因素心理因素

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葡萄褐纹病菌侵染过程的细胞学特性研究

西北农业学报 2024年第7期33卷 1392-1398页

作者：李杰陈浩宇郝敬喆钟海霞张付春伍新宇范咏梅新疆农业科学院植物保护研究所乌鲁木齐830091 新疆农业科学院园艺作物研究所乌鲁木齐830091 海南大学植物保护学院海口570228

为明确褐纹病菌侵染葡萄叶片的过程,采用光学显微镜、扫描电镜和透射电镜等技术手段,系统研究了葡萄褐纹病菌在‘无核白’和‘克瑞森无核’葡萄叶片上的侵染过程。结果表明:葡萄褐纹菌分生孢子在‘无核白’‘克瑞森无核’葡萄叶片接种1 ... 详细信息

为明确褐纹病菌侵染葡萄叶片的过程,采用光学显微镜、扫描电镜和透射电镜等技术手段,系统研究了葡萄褐纹病菌在‘无核白’和‘克瑞森无核’葡萄叶片上的侵染过程。结果表明:葡萄褐纹菌分生孢子在‘无核白’‘克瑞森无核’葡萄叶片接种1 d后均可萌发;后期发育过程,‘克瑞森无核’葡萄叶片上菌丝细长,生长停滞;‘无核白’葡萄叶片表面初生菌丝密布,持续在寄主体表生长扩展;接种3 d,‘无核白’葡萄叶片的表面形成了密集的菌丝网,同时观察到菌丝从气孔或直接入侵方式进入叶片表皮组织内部,随后,菌丝以胞间和胞内生长的方式扩展;接种6 d,菌丝达到上表皮,随菌丝在叶片组织内不断地生长扩展,使得寄主细胞坏死、解体。可见:‘无核白’是亲和葡萄褐纹病菌品种,而‘克瑞森无核’葡萄非亲和褐纹病菌。

关键词：葡萄褐纹菌 ‘无核白’ 克瑞森无核侵染过程细胞学研究

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Salt-induced hydrogen peroxide is involved in modulation of antioxidant enzymes in cotton

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The Crop Journal 2016年第6期4卷 490-498页

作者： Yan Wang Xiangqian Li Jinyao Li Qian Bao fuchun zhang Gulinuer Tulaxi Zhicai Wang Xinjiang Key Laboratory of Biological Resources and Genetic Engineering College of Life Science and TechnologyXinjiang University

Salt severely restricts cotton(Gossypium hirsutum) growth and *** present study was undertaken to study the effect of salt-induced hydrogen peroxide(H_2O_2) on antioxidant enzymes in *** Cl treatment or exogenous H_2O_2 was used to investigate the relationship between H_2O_2 content and levels of antioxidant enzymes including superoxide dismutase(SOD),ascorbate peroxidase(APX),peroxidase(POD),and catalase(CAT),as well as the transcriptional levels of corresponding genes.H_2O_2 content increased within 24 h following 200 mmol L^(–1)Na Cl *** Na Cl-induced and exogenous H_2O_2 increased the activity of antioxidant enzymes including APX and SOD and upregulated the transcriptional levels of Ghc APX1,Gh Fe SOD,and Ghchl *** increased activities and upregulated transcriptional levels were inhibited when the salt-induced H_2O_2 was scavenged by *** results indicate that salt-induced H_2O_2 as a second signaling messenger modulates APX and SOD activities by regulating the transcription levels of corresponding genes,alleviating oxidative stress,and increasing salt tolerance in cotton.

关键词： Cotton Salt stress Hydrogen peroxide Antioxidant enzyme Transcriptional regulation

The Limitation of Rapid Tests for DENV2 Infection in Host with Unique Immune Status:Low NS1 Antigenemia and Deficient Antibody Responses

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Virologica Sinica 2020年第4期35卷 478-480页

作者： Lei Yu Yingfen Wen Mengrong Xiang Wenxin Hong Lingzhai Zhao fuchun zhang Guangzhou Eighth People’s Hospital Guangzhou Medical UniversityGuangzhou 510060China

Dear Editor,Dengue infections are caused by all four serotypes of dengue virus(DENV1–4).In recent years it has been confirmed that DENV-1 and DENV-2 are co-circulated in Guangzhou,Guangdong,China(Lai et al.2015;Luo et al.2017).DENV-2 strains were imported from Thailand and Indonesia(Luo et al.2017;Zhao et al.2014,2016),and had become the second local circulated serotype in Guangzhou.

关键词： al. Antigen Antibody

Cloning,sequencing and prokaryotic expression of cDNAs for antifreeze protein family from Beetle Tenebrio molitor

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Frontiers in Biology 2008年第3期3卷 279-286页

作者： Zhongyuan LIU Yun WANG Guodong LÜ Xianlei WANG fuchun zhang Ji MA College of Life Science and Technology Xinjiang UniversityXinjiang Key Laboratory of Biological Resources and Genetic EngineeringUrumqi 830046China

Partial cDNA sequences coding for antifreeze proteins in Tenebrio molitor were obtained by *** analysis revealed nine putative cDNAs with a high degree of homology to Tenebrio molitor antifreeze protein genes published in *** recombinant pGEX-4T-1-tmafp-XJ430 was introduced into *** BL21 to induce a GST fusion protein by ***-PAGE analysis for the fusion protein shows a band of 38 ***3-tmafp-XJ430 was injected into mice to generate antiserum which was later detected by indirect *** titer of the antibody was 1:*** blotting analysis shows that the antiserum was specifically against the antifreeze *** results laid the foundation for further studies on the properties and functions of insect antifreeze proteins.

关键词： Tenebrio molitor antifreeze proteins cDNA fragment sequence analysis prokaryotic expression

Association between serum albumin levels and disease severity in adult patients with dengue: A 7-year retrospective cohort study in China's Mainland

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Asian Pacific Journal of Tropical Medicine 2023年第5期16卷 204-212,I0001页

作者： Changtai Wang Huiqin Yang Jielan Xu Jian Wang Lingzhai Zhao Wenxin Hong fuchun zhang Department of Infectious Disease Guangzhou Eighth People's HospitalGuangzhou Medical UniversityGuangzhouChina Department of Clinical Laboratory Guangzhou Eighth People's HospitalGuangzhou Medical UniversityGuangzhouChina Department of Infectious Disease Guangzhou Red Cross HospitalJinan UniversityGuangzhouChina

Objective:To identify the association between serum albumin levels and disease severity among adult patients with dengue in China's ***:This retrospective cohort study analyzed the data of adult patients(aged≥18 years)hospitalized with laboratory-confirmed dengue in a tertiary center for infectious diseases from 2013 to 2019 in China's *** albumin levels were estimated and compared between patients with severe dengue and non-severe ***,the association between serum albumin levels and severe dengue was evaluated using a generalized linear model[relative risks(RR)].Multivariate logistic regression analysis was performed to identify the potential predictors of severe ***:Overall,1568 patients were included in this *** these patients,34(2.17%)developed severe *** median serum albumin levels were significantly lower in patients with severe dengue than that in those with non-severe dengue(33 g/L vs.37 g/L,P<0.001).After adjustment for age,sex,and comorbidities,hypoalbuminemia(RR 4.877,95%CI 2.193-11.461,P<0.001)was found to be a predictor of severe *** albumin levels(OR 1.303,95%CI 1.161-1.462,P<0.001)and age(OR 1.038,95%CI 1.017-1.061,P<0.001)were significant risk factors for severe *** area under the curve for serum albumin levels to distinguish severe dengue was ***:Lower serum albumin levels were significantly associated with disease severity in adult patients with *** on admission resulted in at least a four-fold increased risk of severe dengue.

关键词： Dengue Severe dengue Serum albumin Hypoalbuminemia Prediction

老年登革热患者并发急性肾损伤的临床特征分析

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热带病与寄生虫学 2024年第4期22卷 212-216页

作者：王长泰杨慧琴金康虹冷星宇张振华张复春安徽医科大学第二附属医院安徽合肥230601 广州医科大学附属市八医院

目的探讨老年登革热患者并发急性肾损伤(acute kidney injury,AKI)的临床特征及其相关危险因素,为老年登革热的临床诊治提供参考。方法选取2013年1月—2019年12月于广州医科大学附属市八医院住院的老年登革热患者,比较AKI组和非AKI组的... 详细信息

目的探讨老年登革热患者并发急性肾损伤(acute kidney injury,AKI)的临床特征及其相关危险因素,为老年登革热的临床诊治提供参考。方法选取2013年1月—2019年12月于广州医科大学附属市八医院住院的老年登革热患者,比较AKI组和非AKI组的临床特征,并运用多因素logistic回归分析筛选并发AKI的相关危险因素。结果共纳入老年登革热患者423例,其中并发AKI患者30例(占7.09%)。AKI组年龄为76(68,82)岁,非AKI组为69(63,77)岁,差异有统计学意义(Z=-3.100,P<0.05);AKI组与非AKI组查尔森合并症指数(Chalson's comorbidity index,CCI)评分<3分的分别为19例(占63.33%)、334例(占84.99%),差异有统计学意义(χ^(2)=7.709,P<0.05)。实验室指标中,AKI组与非AKI组的血钾[3.46(3.11,3.79)mmol/L vs.3.28(2.98,3.58)mmol/L]、C反应蛋白水平[6.35(3.78,28.17)mg/L vs.2.50(0.88,5.93)mg/L]、红细胞比容[37.40(33.58,41.00)%vs.39.70(36.60,42.45)%]比较,差异均有统计学意义(Z=2.038、3.866、-2.186,P均<0.05)。AKI组重症登革热病例与非AKI组的重症病例构成[(15例,占50.00%)vs.(21例,占5.34%)]、住院天数[7.5(5,10)d vs.5(4,7)d]比较,差异均有统计学意义(χ^(2)=65.765,Z=-3.802,P均<0.05)。多因素logistic回归分析显示,年龄[OR=1.068,95%CI:(1.020,1.119)]、C反应蛋白水平[OR=1.014,95%CI:(1.004,1.025)]和CCI评分≥3分[OR=2.672,95%CI:(1.176,6.069)]是老年登革热患者并发AKI相关危险因素。结论老年登革热患者AKI发生率较高,且与不良预后相关,较高的年龄、C反应蛋白水平和CCI评分可能会增加AKI的发生风险。提示临床上对于老年登革热患者应尽早发现AKI并积极干预,以改善预后。

关键词：登革热急性肾损伤老年患者临床特征危险因素