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Acta Metallurgica Sinica(English Letters) 2014年第1期27卷 27-30页

作者： Jiaohong Huang Naikun Sun Cuilan Liu yumei ge Tao Zhang Feng Liu Pingzhan Si Baotou Research Institute of Rare Earths School of Science Shenyang Ligong University College of Materials Science and Engineering China Jiliang University

Bulk ***11.4Sil.6 compound exhibits a large magnetic-entropy change ASm of 28.1 J/（kg K） for a magnetic-field change from 0 to 1.5 T at the Curie temperature, Tc of 186 K, accompanied by a large magnetic hysteresis of 56 J/kg and a noticeable thermal hysteresis of about 1 K. If the bulk sample is ground into middle-size particles （30-60 tm）, then the thermal hysteresis is almost eliminated and the magnetic hysteresis loss is decreased by 29%, while the large ASm maintains. Especially, fine powder with an average size of 2 tm shows the same Tc as the bulk and does not lose stability. Meanwhile, a comparatively large ASm of 13.9 J/（kg K） and a hysteresis reduction of 70% are attained. The hysteresis reduction can be ascribed to the decrease of internal strains and to the improvement of heat transfer due to the increase of the ratio of the surface area to the volume.

关键词： Magnetocaloric effect Magnetic hysteresis Particle size

Serum exosomes miRNA27a and miRNA200a are considered to diagnostic markers for pancreatic

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Serum exosomes miRNA27a and miRNA200a are considered to diag...

2019年浙江省检验医学学术大会

作者： Zhao Zhao yumei ge Department of Clinical Laboratory Zhejiang Provincial People’s Hospital

OBJECTIVE: The aim of study is to investigate the differentially expression of serum exosome miRNAs in pancreatic cancer patients, and provide a new basis for the diagnosis of pancreatic cancer. METHODS: Illumina high-throughput sequencing technique was used for investigating the differentially expression of serum exosome miRNAs in pancreatic cancer. Real-time fluorescent PCR was used to further verify, and biological information was used for survival analysis. RESULTS: 44 differential miRNAs were identified between Pancreatic Cancer group and healthy control group, 36 upregulated, 8 down-regulated. 4 up-regulated and 2 down-regulated miRNA were selected for PCR verification. It was found that there were significant differences in miRNA27 a and miRNA200 a between pancreatic cancer patients and healthy controls. CONCLUSION: Serum exosome miRNA27 a and miRNA200 a could be the new diagnostic markers of pancreatic cancer,and provide a theoretical basis for the early diagnosis of pancreatic cancer.

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Normal blood D-dimer concentrations： do they exclude pulmonary embolism？

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Chinese Medical Journal 2014年第1期127卷 18-22页

作者： Guo Zhiguo Ma Qingbian Zheng Yaan Zhang yumei ge Hongxia Department of Emergency Medicine Peking University ThirdHospital Beijing 100191 China

Background Although pulmonary embolism （PE） with normal blood D-dimer （DD） concentrations is considered rare,in practice the incidence may be greater than is generally *** PE is potentially *** aim of this study was to explore the incidence and clinical features of PE with normal DD *** We retrospectively analyzed the records of 29 patients with PE and normal DD concentrations from the past seven *** here compare relevant clinical characteristics of these patients with those of patients with PE and abnormal DD *** evaluated the probabilities of differences by computing pretest probability scores （Wells score and revised geneva score）.Results The frequency of normal DD concentrations in patients with PE was 4％.Previous episode（s） of PE were more common in patients with normal DD concentrations than in those with abnormal DD concentrations （P=0.001）.Fever,tachycardia,and tachypnea occurred less frequently in the former group （P＜0.05） and time between onset of symptoms and DD testing was longer （P=0.001）.The diagnosis of PE was delayed in 22 of the 29 *** and seven cases with normal DD concentrations were classified according to pretest scores as intermediate and low risk,*** PE with normal DD concentrations is *** most diagnoses of PE are ruled out by normal DD values,a small number of cases with PE are missed.A combination of pretest probability score and normal DD concentration increases the probability of making the correct diagnosis,but cannot completely exclude patients with suspected *** the clinical manifestations cannot be otherwise explained,clinicians should be alert to the possibility of PE with normal DD concentrations in patients with previous episode（s） of PE or a long interval between onset of symptoms and DD testing.

关键词： pulmonary embolism diagnosis D-dimer

Dysregulated Tfh subset in secondary and latent syphilis patients

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Dysregulated Tfh subset in secondary and latent syphilis pat...

2019年浙江省医学会医学微生物与免疫学分会学术大会

作者： yumei ge Zhaozhao Yonglie Zhou Chunmei Ye Jinlin Liu Department of Clinical Laboratory Zhejiang Provincial People's HospitalHangzhou Medical College Zhejiang Chinese Medicine University Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province

Objective:The aim of the present study was to examine changes of cellular homeostasis in T follicular helper(Tfh)cells in secondary syphilis patients and latent ***:Thirty healthy controls(HCs),24 secondary syphilis patients and 41 latent syphilis patients were *** percentages of total Tfh,ICOS+Tfh,PD-1+Tfh,resting Tfh,effector Tfh,naive Tfh,effector memory Tfh,central memory Tfh and Tfh1,Tfh2,Tfh17 cells in the peripheral blood were all determined by the flow ***:Comparing to the HCs,the percentage of total Tfh cells was significantly higher in secondary syphilis *** the ICOS+Tfh,PD-1+Tfh,resting Tfh,effector Tfh,naive Tfh,effector memory Tfh,central memory Tfh,Tfhl,Tfh2 and Tfh17 *** the percentage of Tfh17,ICOS+Tfh and effector memory Tfh cells were significantly increased in secondary syphilis patients and decreased in latent syphilis ***,the percentage of Tfh2 cells were significantly increased in latent syphilis patients,while the Tfhl cells were significantly decreased in secondary syphilis patients,and the percentage of PD-1+Tfh cells was increased,while the naive Tfh cells were decreased in the secondary syphilis patients when compared to the *** no significant change was found on the resting Tfh,effector Tfh and central memory Tfh among the HCs and secondary syphilis patients or the latent syphilis ***:Dysregulated Tfh17,ICOS+Tfh or the effector memory Tfh cells may play an important role in the immune evasion of the latent syphilis patients.

关键词： Tfh17 cells ICOS+Tfh effector memory Tfh Secondary syphilis Latent syphilis.Short title:Tfh17 cells in syphilis

Circulating Tfr cells are increased in latent syphilis patients

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Circulating Tfr cells are increased in latent syphilis patie...

2019年浙江省医学会医学微生物与免疫学分会学术大会

Objective:The host immune response could be critical in the pathogenesis of Treponema pallidum(Tp) in latent syphilis *** aim of the present study was to examine changes of cellular homeostasis in T follicular regulatory T(Tfr) cells in secondary syphilis patients and latent syphilis ***:Thirty healthy controls(HCs),24 secondary syphilis patients and 41 latent syphilis patients were *** percentages of total Tfr,Tfrl,Tfr2,Tfr17,and the PD-1,ICOS and CTLA-4 on the Treg cells,CXCR5-Treg cells and Tfr cells in the peripheral blood were all determined by the flow ***:Comparing to the HCs and secondary syphilis patients,the percentage of total Tfr cells and the Tfr/Tfh ratio was significantly higher in latent syphilis patients,while the total Treg cells were not significant changed in the latent syphilis patients when compared to the secondary syphilis ***,no significant change was found on the Tfrl,Tfr2,Tfr17 among the HCs and secondary syphilitic infection patients or the latent syphilis patients,except the Tfr2 cells were increased in the latent syphilis ***,the ICOS and CTLA-4 percentages were all significantly increased on the Tfr cells in latent syphilis patients when compared to the secondary syphilis ***:Increased Tfr cells may play an important role in the immune evasion of Tp in latent syphilis patients.

关键词： Tfr cells CTLA-4 Secondary syphilis Latent syphilis

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走向人神的本主:大理白族地区的精神信仰

民俗研究 2022年第5期 111-120页

作者：葛玉梅山东大学哲学与社会发展学院暨犹太教与跨宗教研究中心山东济南250100

本主崇拜是大理白族极具特色的信仰形态,深刻地影响着大理白族民众的日常生活。若从时间上看,在唐南诏国时期已经有了本主崇拜观念及其信仰形态,而到宋元大理国时期则有了成熟而典型的本主信仰形态,到了明朝初期则再发展成白族普遍性的... 详细信息

本主崇拜是大理白族极具特色的信仰形态,深刻地影响着大理白族民众的日常生活。若从时间上看,在唐南诏国时期已经有了本主崇拜观念及其信仰形态,而到宋元大理国时期则有了成熟而典型的本主信仰形态,到了明朝初期则再发展成白族普遍性的本主信仰体系。若从宗教学视角看,本主信仰表现出强烈的人神崇拜属性:从异质性的他者到人的道德圆成者,再到现实生活中的人,本主身上所呈现的人的属性越来越强,其作为核心的特质也越来越突出。大理白族地区围绕本主建构的人神崇拜,拉近了人与神灵之间的距离,从而围绕本主庙形成了一个互动性的村落生存共同体。

关键词：本主本主庙人神崇拜白族大理

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高墩大跨连续梁铁路桥动力试验

西南交通大学学报 2006年第3期41卷 349-354页

作者：施洲夏招广葛玉梅西南交通大学土木工程学院四川成都610031 西南交通大学应用力学与工程系四川成都610031

为检验桥跨结构的实际动力性能,对主跨100 m,墩高99 m的松头江连续梁铁路桥进行了全桥动力试验,测试其自振特性以及列车以不同速度通过桥跨和在桥上制动时桥跨结构的动力响应.将实测结果与车桥耦合振动分析结果进行了比较,二者基本相符... 详细信息

为检验桥跨结构的实际动力性能,对主跨100 m,墩高99 m的松头江连续梁铁路桥进行了全桥动力试验,测试其自振特性以及列车以不同速度通过桥跨和在桥上制动时桥跨结构的动力响应.将实测结果与车桥耦合振动分析结果进行了比较,二者基本相符.结果表明,该桥具有良好的竖向刚度、横向刚度和结构强度;列车在桥上运行时对桥跨结构有一定的冲击作用,而列车行车具有良好的安全性与舒适度.

关键词：车-桥耦合振动高墩连续梁自振特性动载试验

Detection and analysis of herpes simplex virus type Ⅱ infection in 2008-2017 by fluorescence PCR

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Detection and analysis of herpes simplex virus type Ⅱ infec...

2019年浙江省医学会医学微生物与免疫学分会学术大会

作者： Zhao Zhao Hu Qingfeng Zhou Yonglie Lv Huoyang ge yumei Center of Clinical Laboratory Medicine the Zhejiang Provincial People’s HospitalPeople’s Hospital of Hangzhou Medical College

Objective To investigate the suspected patients with genital herpes simplex virus type Ⅱ infection in Zhejiang,in order to provide reference for clinical prevention and *** Real-time fluorescene quantitative PCR was used to test herpes simplex virus type Ⅱ nucleic acid of 2230 cases of suspected outpatients with genital herpes from 2008 to 2016 in the Zhejiang Provincial People’ s *** The positive rate of 2230 casas of outpatients with suspected genital herpes including 1554 female cases and 676 male cases was 24.98%(557/223)with HSV-Ⅱ.The positive rate of 26.06% among females(405/1554);male positive rate was 22.49%(152/676),there was no significant difference of the positive detection rate between male and female(P>0.05).Five age groups were age 50 years,the positive detection rate of this Five age groups was 3.05%(17 cases),42.01%(234 cases),29.80%(166 cases),14.72%(82 cases),10.23%(57 cases),*** The detection rate of HSV-Ⅱ in the outpatients with suspected genital herpes infection was high in Zhejiang,which illustrated that clinical diagnosis should pay attention to detect HSV-Ⅱ nucleic acid in outpatients with suspected genital herpes *** was no difference of HSV-Ⅱ infection between male and female,but the highest positive detection rate of HSV-Ⅱ DNA was among 20-50 years ***-time quantitative PCR was compatible for clinical application with its features of fast,high sensitivity,simplicity in detection of HSV-Ⅱ.

关键词： Herpes simplex virus type Ⅱ(HSV-Ⅱ) Real-time fluorescene quantitative PCR genitourinary tract

Detection of Chlamydia trachomatis in patients with genitourinary tract infections in 2017 by PCR fluorescence probe method

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Detection of Chlamydia trachomatis in patients with genitour...

2019年浙江省医学会医学微生物与免疫学分会学术大会

作者： ge yumei Zhao Zhao Hu Qingfeng Zhou Yonglie Lv Huoyang Sun Aihua Center of Clinical Laboratory Medicine the Zhejiang Provincial People’s HospitalPeople’s Hospital of Hangzhou Medical College

Objective In order to understand the infection of CT in patients with genitourinary tract inflammation in Zhejiang province,and to provide laboratory basis for clinical diagnosis and treatment,Chlamydia trachomatis(CT) nucleic acid in genitourinary tract was detected by fluorescent *** Pathogen nucleic acid was extracted from secretion samples by magnetic bead ***-DNA was detected in 13650 suspected urogenital tract infection patients in Zhejiang People’s Hospital from January 1,2017 to December 31,2017 by real-time fluorescent *** 11164 were female and 2486 were male of the 13650 suspected urogenital tract infections.A total of1310 were positive for CT-DNA,with a positive rate of 9.60%(1310/13650).Among 1310 patients with CT infection,1159(10.38%) were female,151(6.07%) were male,and the infection rate of female was higher than that of male.13650 patients with suspected genitourinary tract infection were divided into 6 age groups,namely 60 years *** proportion of each age group was 3.31%(452 cases),38.99%(5322 cases),38.10%(5200 cases),14.12%(1927 cases),4.09%(558 cases)and 1.40%(191 cases),*** The detection rate of CT infection in patients with genitourinary tract inflammation is high,suggesting that clinical attention should be paid to CT detection of this *** addition,the fluorescent PCR method for the detection of CT infections in genitourinary tract has the advantages of rapid,high sensitivity,high specificity,simple and suitable for clinical promotion.

关键词： Chlamydia trachomatis Real-time fluorescene quantitative PCR genitourinary tract infections

Epidemiological characteristics of Chlamydia trachomatis infection in reproductive tract in Zhejiang Province in 2008-2017

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Epidemiological characteristics of Chlamydia trachomatis inf...

2019年浙江省医学会医学微生物与免疫学分会学术大会

作者： ge yumei Zhao Zhao Zhou Yan Hu Qingfeng Zhou Yonglie Lv Huoyang Sun Aihua Center of Clinical Laboratory Medicine the Zhejiang Provincial People’s HospitalPeople’s Hospital of Hangzhou Medical College

Objective:To understand the epidemiological characteristics and development trend of Chlamydia trachomatis(CT) infection in patients with genitourinary tract inflammation in Zhejiang province,and to provide reference for clinical diagnosis,treatment and ***:Real-time fluorescent PCR was used to detect CT-DNA in suspected urogenital tract infection patients in Zhejiang People’s Hospital from 2008 to 2017,and the results were analyzed ***:There were 37427 suspected urogenital tract infections from 2008 to *** them,30815 were female patients and 6612 were male patients.A total of 3541 cases were CT-DNA positive,with a positive rate of9.46%(3541/37427).Among 3541 patients with CT infection,3061 were female positive,the positive rate was 9.93%(3061/30815),480 were male positive,the positive rate was 7.26%(480/6612).From 2008 to 2017,the positive rates were 14.29%(4 cases),14.51%(28 cases),7.5%(3 cases),10.08%(12 cases),11.17%(22 cases),7.90%(56 cases),10.28%(145 cases),9.73%(911 cases),8.96%(1050 cases) and 9.60%(1310 cases),***:In recent years,the number of patients with genitourinary tract inflammation and the number of patients with positive CT infection are increasing,suggesting that clinical attention should be paid to CT-DNA detection of these diseases,and the scope of CT screening should be expanded.

关键词： Chlamydia trachomatis Epidemiological characteristics reproductive tract infections