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Progress in Electrospun Fibers for Manipulating Cell Behaviors

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Advanced Fiber Materials 2023年第4期5卷 1241-1272页

作者： Yingnan Liu Qingxia Guo Xiaopei Zhang yuanfei wang Xiumei Mo Tong Wu Institute of Neuroregeneration and Neurorehabilitation Qingdao Medical CollegeQingdao UniversityQingdao 266071ShandongChina State Key Laboratory for Modification of Chemical Fibers and Polymer Materials Donghua UniversityShanghai 201620China Central Laboratory Qingdao Stomatological Hospital Affiliated to Qingdao UniversityQingdao 266001ShandongChina College of Chemistry Chemical Engineering and BiotechnologyDonghua UniversityShanghai 201620China Shandong Key Laboratory of Medical and Health Textile Materials Collaborative Innovation Center for Eco‑textiles of Shandong Province and the Ministry of EducationCollege of Textiles&ClothingQingdao 266071ShandongChina

The manipulation of cell behaviors is essential to maintaining cell functions,which plays a critical role in repairing and regenerating damaged *** this end,a rich variety of tissue-engineered scaffolds have been designed and fabricated to serve as matrix for supporting cell growth and *** others,scaffolds made of electrospun fibers showed great potential in regulating cell behaviors,mainly owing to their capability of replicating the dimension,composition,and function of the natural extracellular *** particular,electrospun fibers provided both topological cues and biofunctions simply by adjusting the electrospinning parameters and/or *** this review,we summarized the most recent applications and advances in electrospun nanofibers for manipulating cell ***,the engineering of the secondary structures of individual fibers and the construction of two-dimensional nanofiber mats and nanofiber-based,three-dimensional scaffolds were ***,the functionalization strategies,such as endowing the fibers with bioactive,physical,and chemical cues,were ***,the typical applications of electrospun fibers in controlling cell behaviors(i.e.,cell adhesion and proliferation,infiltration,migration,neurite outgrowth,stem cell differentiation,and cancer cell capture and killing)were *** together,this review will provide valuable information to the specific design of nanofiber-based scaffolds and extend their use in controlling cell behaviors for the purpose of tissue repair and regeneration.

关键词： Electrospun nanofibers Structures Functionalization Cell behaviors Tissue repair and regeneration

Antibiotic Metabolites from the Coral-Associated Actinomycete Streptomyces sp. OUCMDZ-1703

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Chinese Journal of Chemistry 2013年第1期31卷 100-104页

作者： Peng Fu Fandong Kong yuanfei wang Yi wang Peipei Liu Guoying Zuo Weiming Zhu Key Laboratory of Marine Drugs Ministry of Education of China School of Medicine and Pharmacy Ocean University of China Qingdao Shandong 266003 China Research Center for Natural Medicines Kunming General Hospital PLA Kunming Yunnan 650032 China Yunnan Traditional Chinese Medical College Kunming Yunnan 650500 China

From the oligotrophic culture of a soft coral-associated actinomycetes strain, Streptomyces sp. OUCMDZ-1703, we isolated and identified two new chlorinated polyketides that we named strepchloritides A and B （1 and 2）, three thiazole derivatives known as watasemycin A （3）, pulicatin G （4） and aerugine （5）, along with pyrrole- 2-carboxamide, furan-2-carboxamide and 1-（3,5-dihydroxyphenyl）ethanone. The new structures of 1 and 2 were determined by spectroscopic studies such as 1D- and 2D-NMR and MS analyses, while the known compounds were identified by comparison of the NMR data with those in literatures. The results showed that actinomycete strain OUCMDZ-1703 could use the relative high ratio of chlorine in the oligotrophic medium to synthesize chlorinated natural products. New compounds 1 and 2 displayed cytotoxicity against the MCF-7 ceils with ICs0 values of 9.9 and 20.2 ~tmoloL-1, respectively. Thiazole derivatives 3 and 5 were first found to be active against three clinical strains of methicillin-resistant Staphylococcus aureus （MRSA082, MRSA111 and MRSA234） with the same MIC/MBC values of 7.81/7.81 μg·mL-1.

关键词： coral-associated actinomycetes Streptomyces sp. polychlorinated natural products thiazole deriva-tives cytotoxicity antibiotic methicillin-resistant S. aureus

Multi-antenna synchronized global navigation satellite system receiver and its advantages in high-precision positioning applications

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Frontiers of Earth Science 2016年第4期10卷 772-783页

作者： Danan DONG Wen CHEN Miaomiao CAI Feng ZHOU Minghua wang Chao YU Zhengqi ZHENG yuanfei wang Engineering Center of SHMEC for Space Information and GNSS East China Normal University Shanghai 200241 China Shanghai Key Laboratory of Multidimensional Information Processing East China Normal University Shanghai 200241 China Key Laboratory of Geographic Information Science Ministry of Education East China Normal University Shanghai 200241 China College of Surveying and Geo-informatics Tongji University Shanghai 200092 China

The multi-antenna synchronized global navi- gation satellite system receiver is a high precision, low cost, and widely used emerging receiver. Using this type of receiver, the satellite and receiver clock errors can be eliminated simultaneously by forming between antenna single-differences, which is equivalent to the conventional double-difference model. However, current multi-antenna synchronized global navigation satellite system receiver products have not fully realized their potential to achieve better accuracy, efficiency, and broader applications. This paper introduces the conceptual design and derivable products of multi-antenna synchronized global navigation satellite system receivers involving the aspects of attitude determination, multipath effect mitigation, phase center variation correction, and ground-based carrier phase wind- up calibration. Through case studies, the advantages of multi-antenna synchronized global navigation satellite system receivers in high-precision positioning applications are demonstrated.

关键词： multi-antenna synchronized global navigationsatellite system receiver high-precision positioning attitudedetermination multipath effect mitigation phase centervariation correction ground-based carrier phase wind-upcalibration

Revealing the Circadian Rhythm of Taliang Crocodile Newt(Liangshantriton taliangensis) During Breeding Migration Using a Novel Monitoring Technique

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Asian Herpetological Research 2023年第3期14卷 227-236页

作者： Haoqi YU yuanfei wang Liuyang HE Yudong ZHU Xiuqin LIN Luyao XIAO Cheng LI Jianping JIANG Feng XIE CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization and Ecological Restoration Biodiversity Conservation Key Laboratory of Sichuan Province Chengdu Institute of BiologyChinese Academy of SciencesChengdu 610041SichuanChina University of Chinese Academy of Sciences Beijing 100049China College of Life Sciences Sichuan UniversityChengdu 610065SichuanChina Mangkang Biodiversity and Ecological Station Xizang Ecological Safety Monitor NetworkChangdu 854500TibetChina Open Laboratory of Shimian Research Center of Giant Panda Small Population Conservation and Rejuvenation and Liziping Giant Panda′s Ecology and Conservation Observation and Research Station of Sichuan Province Sichuan Liziping National Nature ReserveYa′an 625000SichuanChina

Many animals migrate during the breeding *** is important to study the patterns of breeding migration of wild animals,especially rare and endangered ***,current data acquisition methods are too coarse and imprecise for investigating the circadian rhythms of migrations in *** on the frustrated total reflection image(FTRI),we developed a new device and recorded the precise migration time of an endangered salamander,Liangshantriton *** the breeding period,a total of 33 individuals were effectively *** of the data indicated that the circadian rhythm of breeding migration in *** was bimodal,and migration mainly occurred from 05:00 to 13:00(81.82%of the total migration records).The average relative activity intensity index(RAI)of breeding migration peaked in the temperature range of 14.0–16.0°*** increased average relative air humidity,the activity intensity first increased and then decreased,reaching a peak in the humidity range of 91.0%–97.0%.These results demonstrate that our new device is a viable and accurate method for recording the migration time of target *** is important to reveal the breeding migration pattern of ***,which is important for the conservation of this ***,this new device can be used for field monitoring and conservation studies of amphibians,reptiles and other animals.

关键词： diel pattern frustrated total reflection image Liangshantriton taliangensis new device weather factors

Smart Design and Manufacturing the Welded Q350 Steel Frames via Lifecycle Management Strategy of Digital Twin

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Journal of Beijing Institute of Technology 2023年第4期32卷 385-395页

作者： Letian Fan Xinchao wang Yongsheng Chen Li wang Shumi Liu yuanfei wang Xinwei Li Kun Du Jia Zhang Xingyu Gao Feng Sun Haifeng Song William Yi wang Jinshan Li R&D Center CRRC Tangshan Co.Ltd.Tangshan 063035HebeiChina Innovation Centre NPU ChongqingChongqing 401135China State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China Western Superconducting Technologies Co. Ltd.Xi’an 710018China Chongqing Ti-master Co. LtdChongqing 401135China Laboratory of Computational Physics Institute of Applied Physics and Computational MathematicsBeijing 100088China

Artificial intelligent aided design and manufacturing have been recognized as one kind of robust data-driven and data-intensive technologies in the integrated computational material engi-neering(ICME)*** by the dramatical developments of the services of China Railway High-speed series for more than a decade,it is essential to reveal the foundations of lifecycle man-agement of those trains under environmental ***,the smart design and manufacturing of welded Q350 steel frames of CR200J series are introduced,presenting the capability and opportu-nity of ICME in weight reduction and lifecycle management at a cost-effective *** order to address the required fatigue life time enduring more than 9×10^(6)km,the response of optimized frames to the static and the dynamic loads are comprehensively *** is highlighted that the maximum residual stress of the optimized welded frame is reduced to 69 MPa from 477 MPa of previous existing *** on the measured stress and acceleration from the railways,the fatigue life of modified frame under various loading modes could fulfil the requirements of the lifecycle ***,our recent developed intelligent quality control strategy of welding process mediated by machine learning is also introduced,envisioning its application in the intelligent weld-ing.

关键词： fatigue intelligent manufacturing integrated computational materials engineering(ICME) digital twin machine learning

Salt-Lake Basin Bedrock Weathered Crust Gas Reservoir in the Altun Mountains Front of the Qaidam Basin,Western China

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Acta Geologica Sinica(English Edition) 2023年第5期97卷 1555-1567页

作者： ZHANG Yongshu JIA Chengzao LI Guoxin LI Jiangtao wang Bo ZHAO Fan YUE Dali SHI Zhenghao ZHU Jun wang yuanfei ZHANG Yi CHEN Yangyang ZHANG Fenying YU Xue XU Li Hou Lili SONG Yue School of Earth Sciences China University of Petroleum(Beijing)Beijing 102249China Qinghai Provincial Key Laboratory of Plateau Saline-Lacustrine Basinal Oil&Gas Geology DunhuangGansu 736202China College of New Energy and Materials China University of Petroleum(Beijing)Beijing 102249China

The bedrock weathered crust in front of the Altun Mountains in the Qaidam Basin,western China,is different from others because this is a salt-lake basin,where saline water fluid infiltrates and is deposited in the overlying strata.A large amount of gypsum infills the bedrock weathered crust,and this has changed the pore *** core observation,polarized light microscopy,electron probe,physical property analysis and field emission scanning electron microscopy experiments,the characteristics of the weathered bedrock have been *** are cracks and a small number of dissolved pores in the interior of the weathered *** micropores are widely developed,especially the various matrix cracks formed by tectonics and weathering,as well as the stress characteristics of small dissolved pores,and physical properties such as porosity and ***‘dual structure’developed in the bedrock is important for guiding the exploration of the lake basin bedrock for natural gas.

关键词： upstream gas reservoir bedrock weathered crust cracks matrix micropores salt lake Qaidam Basin

基于MPI的大气污染扩散模型的并行计算研究

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计算机工程 2005年第22期31卷 54-57页

作者：姚丽萍王远飞华东师范大学地理信息科学教育部开放实验室上海200062

基于MPI消息传递实现了多点源高斯扩散模型的并行编程,以数据的分布存储作为区域划分的依据,实现了计算量的负载平衡;通过对算法的改进实现了粗粒度计算,大大减少通信量,提高了程序的执行效率,并对串行计算和并行计算的结果进行了比较... 详细信息

基于MPI消息传递实现了多点源高斯扩散模型的并行编程,以数据的分布存储作为区域划分的依据,实现了计算量的负载平衡;通过对算法的改进实现了粗粒度计算,大大减少通信量,提高了程序的执行效率,并对串行计算和并行计算的结果进行了比较。研究结果表明,将并行计算应用于多点源污染物浓度计算是可行的,并获得较高的加速比,并行效率最高达97.5%,与单机相比,不仅可以提高运行速度,大大缩短计算时间,而且可以扩大计算规模。

关键词：并行计算大气污染扩散加速比

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一种基于奇异值分解的集中式控制器设计

信息与控制 2014年第5期43卷 513-517页

作者：靳其兵王元飞北京化工大学信息科学与技术学院北京100029

针对过程控制中具有不同时滞的多变量强耦合系统,提出了一种基于奇异值分解的解耦控制方法.通过内模原理设计了集中式PI(proportional-integral)控制器,并系统分析了系统的鲁棒稳定性能.该方法能够很好地解决系统耦合问题,且同时适用于... 详细信息

针对过程控制中具有不同时滞的多变量强耦合系统,提出了一种基于奇异值分解的解耦控制方法.通过内模原理设计了集中式PI(proportional-integral)控制器,并系统分析了系统的鲁棒稳定性能.该方法能够很好地解决系统耦合问题,且同时适用于方形和非方系统,能够对多变量系统控制方法做出统一化设计.通过仿真实例研究结果表明了该方法的有效性,并且能够很好地消除模型降阶和系统参数扰动带来的干扰,具有理想的解耦能力和鲁棒性.该方法设计简单,易于工程实施.

关键词：多变量系统时滞解耦奇异值分解内模控制

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基于GIS的上海市购物中心区位评价研究

华中师范大学学报（自然科学版） 2010年第1期44卷 152-157页

作者：武占云王远飞华东师范大学地理信息科学教育部重点实验室上海200062

基于GIS技术,选取人口集聚度、交通通达性和居民购买力作为上海市购物中心区位评价的3个影响因素,并基于空间相互作用模型,建立购物中心区位评价模型,通过区位优势度的计算对上海市购物中心区位的合理性进行了评价.结果表明,虽然上海市... 详细信息

基于GIS技术,选取人口集聚度、交通通达性和居民购买力作为上海市购物中心区位评价的3个影响因素,并基于空间相互作用模型,建立购物中心区位评价模型,通过区位优势度的计算对上海市购物中心区位的合理性进行了评价.结果表明,虽然上海市购物中心普遍位于区位优势度较高的区位,仍有约25%的购物中心规模较大,但区位优势度相对较低,即区位选址存在着不合理性.

关键词：购物中心 GIS 交通通达性人口集聚度居民购买力区位评价