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Diffusion characteristics of HTO and 99TcO_4^- in compacted Gaomiaozi(GMZ) bentonite

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Nuclear Science and Techniques 2017年第5期28卷 60-67页

作者： Tsuey-Lin Tsai Shih-chin Tsai yu-Hung Shih Liang-Cheng Chen Chuan-Pin Lee Te-Yen Su Chemistry Division Institute of Nuclear Energy ResearchNo. 1000 Wenhua Rd. Jiaan Village Longtan DistrictTaoyuan China Nuclear Science and Technology Development Center National Tsing Hua University Hsinchu China Department of Earth Sciences National Cheng Kung University No. 1 University Road Tainan China

The characteristics of diffusion are essential to the transport of radionuclides through buffer/backfill materials, such as bentonite, which are commonly found in waste repositories. This study used through-diffusion techniques to investigate the diffusion behavior of HTO and ^(99)TcO_4^- on GMZ bentonite of various densities. Diffusion rates were calculated by measuring the diffusion coefficients(De, Da), plotting breakthrough curves and interpreting experiment data. The apparent and effective diffusion coefficients of HTO ranged from(1.68 ± 0.40) 9 × 10^(-11) to(2.80 ± 0.62) 9 × 10^(-11) m^2/s and from(4.61 ±1.28) 9 × 10^(-12) to (16.2 ± 2.50) 9 × 10^(-12) m^2/s, *** apparent and effective diffusion coefficients of^(99)TcO_4^-ranged from(5.26 ± 0.16) 9 × 10^-12to(7.78 ± 0.43) 9× 10^-12m^2/s and from(1.49 ± 0.002) 9 × 10^(-12) to(4.16 ±0.07) 9 × 10^(-12) m^2/s, respectively. The distribution coefficients of HTO and^(99)TcO_4^-ranged from(0.70 ± 0.12) 9× 10^(-2) to(1.36 ± 0.53) 9 × 10^(-2) mL/g and from(1.12 ±0.06) 9 × 10^(-2) to(5.79 ± 2.22) 9 × 10^(-2) mL/g, *** Deand Kdvalues were shown to decrease with an increase in the bulk dry density of compacted bentonite. Our results show that HTO and ^(99)Tc could be considered nonsorbent radionuclides. The data obtained in this studyprovide a valuable reference for the safety assessment of waste repositories.

关键词： Distribution coefficient Apparent diffusion coefficient Effective diffusion coefficient Compacted bentonite Through-diffusion

Successful emergency surgical intervention in acute non-STsegment elevation myocardial infarction with rupture:A case report

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World Journal of Clinical Cases 2025年第4期13卷 41-47页

作者： Xing-Po Li Zi-Shan Wang Hong-Xia yu Shan-Shan Wang Department of Cardiovascular Medicine Huantai County Hospital of Traditional Chinese MedicineZibo 256400Shandong ProvinceChina Department of Cardiovascular Medicine Zibo Hospital of Integrated Traditional Chinese and Western MedicineZibo 255500Shandong ProvinceChina

BACKGROUND The incidence of acute myocardial infarction(AMI)is rising,with cardiac rupture accounting for approximately 2%of deaths in patients with acute ST-segment elevation myocardial infarction(STEMI).Ventricular free wall rupture(FWR)occurs in approximately 2%of AMI patients and is notably rare in patients with *** of cardiac rupture include left ventricular FWR,ventricular septal rupture,and papillary muscle *** FWR usually leads to acute cardiac tamponade or electromechanical dissociation,where standard resuscitation efforts may not be *** septal rupture and papillary muscle rupture often result in refractory heart failure,with mortality rates over 50%,even with surgical or percutaneous repair *** SUMMARY We present a rare case of an acute non-STEMI patient who suffered sudden FWR causing cardiac tamponade and loss of consciousness immediate before undergoing coronary *** resuscitation and emergency open-heart repair along with coronary artery bypass grafting resulted in successful patient *** This case emphasizes the risks of AMI complications,shares a successful treatment scenario,and discusses measures to prevent such complications.

关键词： Acute non-ST segment elevation myocardial infarction Cardiac rupture Acute myocardial infarction Free wall rupture Case report

Pan-TRK positive uterine sarcoma in immunohistochemistry without neurotrophic tyrosine receptor kinase gene fusions:A case report

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World Journal of Clinical Cases 2025年第2期13卷 39-49页

作者： Seungmee Lee yu-Ra Jeon changmin Shin Sun-Young Kwon Sojin Shin Department of Obstetrics and Gynecology Keimyung University School of MedicineDaegu 42601South Korea Department of Pathology and Institute for Cancer Research Keimyung University School of MedicineDaegu 42601South Korea

BACKGROUND The classification of uterine sarcomas is based on distinctive morphological and immunophenotypic characteristics,increasingly supported by molecular genetic *** on neurotrophic tyrosine receptor kinase(NTRK)gene fusionpositive uterine sarcoma,potentially aggressive and morphologically similar to fibrosarcoma,are limited due to its recent ***-TRK immunohistochemistry(IHC)analysis serves as an effective screening tool with high sensitivity and specificity for NTRK-fusion *** SUMMARY We report a case of a malignant mesenchymal tumor originating from the uterine cervix,which was pan-TRK IHC-positive but lacked NTRK gene fusions,accompanied by a brief literature review.A 55-year-old woman presented to the emergency department with abdominal pain and distension,exhibiting significant ascites and multiple solid pelvic *** examination revealed a tumor encompassing the uterine cervix,extending to the vagina and uterine corpus.A punch biopsy of the cervix indicated NTRK sarcoma with positive immunochemical pan-TRK ***,subsequent next generation sequencing revealed no NTRK gene fusion,leading to a diagnosis of poorly differentiated,advanced-stage *** The clinical significance of NTRK gene fusion lies in potential treatment with TRK inhibitors for positive *** such rare tumors is crucial due to the potential applicability of tropomyosin receptor kinase inhibitor treatment.

关键词： Uterine sarcoma Cervical sarcoma Neurotrophic tyrosine receptor kinase gene fusion Next generation sequencing Case report

Enrichment of novel Tau isoform with altered biochemical properties in Alzheimer's disease

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Neural Regeneration Research 2023年第11期18卷 2397-2398页

作者： chin-Tong Ong Temasek Life Sciences Laboratory and Department of Biological SciencesNational University of SingaporeSingapore

Aberrant splicing in sporadic Alzheimer’s disease:Alzheimer’s disease (AD) is a progressive neurodegenerative disorder cha racterized by the presence of extracellular amyloid-β plaques and Tau-containing intracellular neurofib rilla ry tangles (Knopman et al.,2021).Cognitive decline in AD due to neuronal and synaptic loss is caused by the complex interplay between pathological amyloid-β and Tau species with the impaired innate clearance *** are two types of AD based on disease aetiology (Knopman et al.,2021).

关键词： Alzheimer impaired

On relationship between curve numbers and phi indices

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Water Science and Engineering 2018年第3期11卷 187-195页

作者： David A.chin Department of Civil Architectural and Environmental Engineering University of Miami

The curve number and phi(4)-index models each provide a simple one-parameter relationship between storm-event rainfall and runoff. It is shown that the curve number and 4-index models can both be used to segregate the rainfall hyetograph into initial abstraction, retention, and runoff amounts. However, the principal advantages of the 4-index model are that both rainfall distribution and duration can be explicitly taken into account in calculating runoff, and the 4 index is more physically based than the curve number. The quantitative relationship between the curve number and the 4 index is presented and validated with field measurements. Knowing the relationship between the curve number and the 4 index is useful in that it facilitates using the extensive database of curve numbers in the more realistic 4-index model in calculating a runoff hydrograph from a given rainfall hyetograph. It is demonstrated that conventional adjustments to curve numbers can be largely explained by variations in storm duration, which suggests that variable rainfall duration can possibly be an essential factor in accounting for deviations from the median curve number of a catchment.

关键词： Infiltration Rainfall Runoff Curve number 4 index Storm duration

Direct Photolithography of WO_x Nanoparticles for High-Resolution Non-Emissive Displays

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NANO-MICRO LETTERS 2025年第1期17卷 1-13页

作者： Gu, chang Yang, Guojian Wang, Wenxuan Shi, Aiyan Fang, Wenjuan Qian, Lei Hu, Xiaofei Zhang, Ting Xiang, Chaoyu Zhang, yu-Mo chinese Acad Sci Ningbo Inst Mat Technol & Engn Lab Optoelect Informat Technol & Devices Ningbo 315201 Peoples R China Qianwan Inst CNITECH Hangzhou Bay Lab Adv Nanooptoelectron Mat & Device Ningbo 315336 Peoples R China Zhejiang Univ Innovat Ctr Yangtze River Delta Smart Mat Architecture Res Lab Jiaxing 314100 Peoples R China Univ Sci & Technol china Hefei 230026 Peoples R China Jilin Univ Coll Chem State Key Lab Supramol Struct & Mat Changchun 130012 Peoples R China

High-resolution non-emissive displays based on electrochromic tungsten oxides (WOx) are crucial for future near-eye virtual/augmented reality interactions, given their impressive attributes such as high environmental stability, ideal outdoor readability, and low energy consumption. However, the limited intrinsic structure of inorganic materials has presented a significant challenge in achieving precise patterning/pixelation at the micron scale. Here, we successfully developed the direct photolithography for WOx nanoparticles based on in situ photo-induced ligand exchange. This strategy enabled us to achieve ultra-high resolution efficiently (line width m, the best resolution for reported inorganic electrochromic materials). Additionally, the resulting device exhibited impressive electrochromic performance, such as fast response ( 3600 cycles), as well as promising applications in electronic logos, pixelated displays, flexible electronics, etc. The success and advancements presented here are expected to inspire and accelerate research and development (R&D) in high-resolution non-emissive displays and other ultra-fine micro-electronics.

关键词： Electrochromic Direct photolithography WOx nanoparticles In situ photo-induced ligand exchange High-resolution displays

Recent progress in quantitative analysis of DNA adducts of nephrotoxin aristolochic acid

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Science china Chemistry 2009年第10期52卷 1576-1582页

作者： yuE Hao chan Wan yu KongJie GUO Lin LIU Ning LIU HuWei CAI ZongWei Department of Chemistry Hong Kong Baptist UniversityHong Kong SARChina changchun University of chinese Medicine Changchun 130117China Fujian Entry-Exit Inspection and Quarantine Bureau Fuzhou 350001China Institute of Analytical Chemistry College of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China

Aristolochic acid (AA), a mixture of structure-related nitrophenanthrene carboxylic acid derivatives derived from Aristolochia spp, is associated with nephrotoxin and carcinogen. AA-DNA adducts induced by reductive metabolic activation of AA were detected in tissues of animals and in patients exposed to AA. The DNA adducts were generally used as biomarkers in toxicological study of AA. In this short review, quantitative analysis of AA-DNA adducts in various in vitro and in vivo systems by using 32P-postlabelling assay, HPLC-UV, HPLC-radiation monitor, HPLC-FLD, HPLC-ESI/MS and UPLC-MS/MS methods is discussed. The distribution of AA-DNA adducts in various tissues is also summarized.

关键词： aristolochic acid DNA adducts quantitative analysis short review

2SWUNet:small window SWin UNet based on tansformer for building extraction from high-resolution remote sensing images

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Optoelectronics Letters 2024年第10期20卷 599-606页

作者： yu Jiamin chan Sixian LEI Yanjing WU Wei WANG yuan ZHOU Xiaolong College of Computer Science and Technology Zhejiang University of TechnologyHangzhou310023China Key Laboratory of Meteorological Disaster(KLME) Ministry of Education&Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD)Nanjing University of Information Science&TechnologyNanjing210044China College of Geographic Information Modern Industry Zhejiang University of TechnologyHangzhou310023China College of Electrical and Information Engineering Quzhou UniversityQuzhou324000China

Models dedicated to building long-range dependencies often exhibit degraded performance when transferred to remote sensing *** transformer(Vi T)is a new paradigm in computer vision that uses multi-head self-attention(MSA)rather than convolution as the main computational module,with global modeling ***,its performance on small datasets is usually far inferior to that of convolutional neural networks(CNNs).In this work,we propose a small window SWin UNet(2SWUNet)for building extraction from high-resolution remote sensing ***,the 2SWUNet is trained based on swin transformer by designing a fully symmetric encoder-decoder U-shaped ***,to construct a reasonable U-shaped architecture for building extraction from high-resolution remote sensing images,different forms of patch expansion are explored to simulate up-sampling operations and recover feature map ***,the small window-based multi-head self-attention(W-MSA)is designed to reduce the computational and memory burden,which is more appropriate for the features of remote sensing ***,the pre-training mechanism is advanced to make up for the lack of decoder ***,comparison experiments with other mainstream CNNs and Vi Ts validate the superiority of the proposed model.

关键词： Net computer resolution

Variable outcome in infantile-onset inflammatory bowel disease in an Asian cohort

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World Journal of Gastroenterology 2016年第48期22卷 10653-10662页

作者： Way Seah Lee Ruey Terng Ng Koon-Wing chan yu-Lung Lau Department of Paediatrics University Malaya Medical Center University Malaya Paediatric and Child Health Research Group University Malaya Department of Paediatrics and Adolescent Medicine Queen Mary Hospital LKS Faculty of Medicine The University of Hong Kong

AIM Infantile-onset inflammatory bowel disease(IO-IBD) with the onset of disease before 12 mo of age, is a different disease entity from childhood IBD. We aimed to describe the clinical features, outcome and role of mutation in interleukin-10(IL-10) and interleukin-10 receptors(IL-10R) in Asian children with IO-IBD. METHODS All cases of IO-IBD, defined as onset of disease before 12 mo of age, seen at University Malaya Medical Center, Malaysia were reviewed. We performed mutational analysis for IL10 and IL10 R genes in patients with presenting clinical features of Crohn's disease(CD).RESULTS Six [13%; CD = 3, ulcerative colitis(UC) = 2, IBDunclassified(IBD-U) = 1] of the 48 children(CD = 25; UC = 23) with IBD have IO-IBD. At final review [median(range) duration of follow-up: 6.5(3.0-20) years], three patients were in remission without immunosuppression [one each for post-colostomy(IBD-U), after standard immunosuppression(CD), and after total colectomy(UC)]. Three patients were on immunosuppression:one(UC) was in remission while two(both CD) had persistent disease. As compared with later-onset disease, IO-IBD were more likely to present with bloody diarrhea(100% vs 55%, P = 0.039) but were similar in terms of an associated autoimmune liver disease(0% vs 19%, P = 0.31), requiring biologics therapy(50% vs 36%, P = 0.40), surgery(50% vs 29%, P = 0.27), or achieving remission(50% vs 64%, P = 0.40). No mutations in either IL10 or IL10 R in the three patients with CD and the only patient with IBD-U were *** The clinical features of IO-IBD in this Asian cohort of children who were negative for IL-10 or IL-10 R mutations were variable. As compared to childhood IBD with onset of disease after 12 mo of age, IO-IBD achieved remission at a similar rate.

关键词： Infantile-onset inflammatory bowel disease Pediatric