检索结果-南通市图书馆

Epidemic obesity in children and adolescents:risk factors and prevention

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Medicine 2018年第6期12卷 658-666页

作者： Eun young lee Kun-Ho Yoon Division of Endocrinology and Metabolism Department of Internal MedicineSeoul St.Mary's HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591Korea Institute of Catholic Ubiquitous Health Care The Catholic University of KoreaSeoul 06591Korea

The prevalence of obesity among children and adolescents (aged 2–18 years) has increased rapidly, with more than 100 million affected in 2015. Moreover, the epidemic of obesity in this population has been an important public health problem in developed and developing countries for the following reasons. Childhood and adolescent obesity tracks adulthood obesity and has been implicated in many chronic diseases, including type 2 diabetes, hypertension, and cardiovascular disease. Furthermore, childhood and adolescent obesity is linked to adulthood mortality and premature death. Although an imbalance between caloric intake and physical activity is a principal cause of childhood and adolescent obesity, environmental factors are exclusively important for development of obesity among children and adolescents. In addition to genetic and biological factors, socioenvironmental factors, including family, school, community, and national policies, can play a crucial role. The complexity of risk factors for developing obesity among children and adolescents leads to difficulty in treatment for this population. Many interventional trials for childhood and adolescent obesity have been proven ineffective. Therefore, early identification and prevention is the key to control the global epidemic of obesity. given that the proportion of overweight children and adolescents is far greater than that of obesity, an effective prevention strategy is to focus on overweight youth, who are at high risk for developing obesity. Multifaceted, comprehensive strategies involving behavioral, psychological, and environmental risk factors must also be developed to prevent obesity among children and adolescents.

关键词： obesity children adolescents epidemiology risk factor prevention

Portal vein stenting as a significant risk factor for biliary stricture in adult living donor liver transplantation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2016年第5期15卷 480-486页

作者： Min-Ho Shin Deok-Bog Moon Sung-Gyu lee Shin Hwang Ki-Hun Kim Chul-Soo Ahn Tae-Yong Ha gi-Won Song Dong-Hwan Jung gil-Chun Park young-In Yun Wan-Jun Kim Woo-Hyoung Kang Seok-Hwan Kim gi-young Ko Division of Hepatobiliary Surgery and Liver Transplantation Department of SurgeryAsan Medical CenterUniversity of Ulsan College of Medicine88 0lympic-ro 43 gilSongpa-guSeoul 05505Korea Department of Radiology and Research Institute of Radiology Asan Medical CenterUniversity of Ulsan College of Medicine88 0lympic-ro 43 gilSongpa-guSeoul 05505Korea

BACKGROUND: Although perioperative portal vein (PV) stent implantation is an effective treatment for steno-occlusive disease in adult living donor liver transplantation (LDLT) re-cipients, we experienced high incidence of biliary anastomotic strictures (BAS) after PV stenting. In this study, we sought to clarify the relation between BAS and PV stenting and to suggest the possible mechanism of BAS and measures to reduce its in-cidence. METHODS: We retrospectively analyzed 44 LDLT recipients who underwent PV stent implantation across the line of PV anastomosis regardless of the location of steno-occlusion (stent group) and their matched controls (non-stented LDLT recipients, n=131). RESULTS: The incidence of BAS was higher in patients in the stent group than that in the control group (43.2% vs 17.6%, P=0.001). Cumulative 6-month and 1-, 2- and 5-year BAS rates were 31.8%, 34.1%, 41.4% and 43.2%, respectively, in the stent group and 13.0%, 13.8%, 16.1% and 17.8%, respectively, in the control group (P=0.001). Multivariate analysis revealed that PV stenting was an independent risk factor for BAS. CONCLUSIONS: Although PV stent implantation is a reliable treatment modality for steno-occlusive PV in adult LDLT recipients, innovative methods to prevent the PV stent from crossing the line of PV anastomosis may be necessary to reduce the incidence of postoperative BAS.

关键词： portal vein stenting biliary stricture living donor liver transplantation

The Influx of the Tsushima Current into the Central Ulleung Basin of East Sea (Sea of Japan), Korea

在线全文

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2014年第6期88卷 1846-1851页

作者： young-Suk BAK Seong-Joo lee The Earth and Environmental System Research Center Chonbuk National University Department of Geology Kyungpook National University

A total of 85 samples, collected from the UBGH1-9 core taken from the Ulleung Basin, East Sea, Korea, were analyzed using diatom assemblages. 111 diatom species belonging to 46 genera were identified, and three diatom assemblage zones were established on the basis of occurrence and distribution pattern of diatoms. Diatom assemblage zone I（134.10–174 m） is characterized by a relatively high abundance of marine species, while the increased number of the brackish species is recorded in diatom assemblage zone II（75–125 m）. The assemblage zones IIIa became drastic drop of valve abundances and brackish planktons, whereas it became increase during the IIIb. High Td values which indicate an influence of warm current are recorded both in diatom assemblage zone I and III, and low Td values in diatom assemblage zone II. Analysis of diatom assemblages indicating that the depositional condition moved from oceanic to littoral-neritic environments and that paleotemperature underwent a shift from warm to cold condition at the middle interval, and from cold to warm condition in the upper interval of the UBGH1-9 core. This suggests that the lower（130–162 m） and upper intervals（0–20 m） of the UBGH1-9 core were deposited in the warm current condition（Tsushima Warm Current）.

关键词： assemblage depositional littoral drastic genera abundance oceanic Korea valve preservation

Estimation of Turbulent Sensible Heat and Momentum Fluxes over a Heterogeneous Urban Area Using a Large Aperture Scintillometer

在线全文

学校读者我要写书评

暂无评论

Advances in Atmospheric Sciences 2015年第8期32卷 1092-1105页

作者： Sang-Hyun lee Jun-Ho lee Bo-young KIM Department of Atmospheric Science Kongju National University Department of Optical Engineering Kongju National University

The accurate determination of surface-layer turbulent fluxes over urban areas is critical to understanding urban boundary layer （UBL） evolution. In this study, a remote-sensing technique using a large aperture scintillometer （LAS） was investigated to estimate surface-layer turbulent fluxes over a highly heterogeneous urban area. The LAS system, with an optical path length of 2.1 km, was deployed in an urban area characterized by a complicated land-use mix （residential houses, water body, bare ground, etc.）. The turbulent sensible heat （QH） and momentum fluxes （z） were estimated from the scintillation measurements obtained from the LAS system during the cold season. Three-dimensional LAS footprint modeling was introduced to identify the source areas （＂footprint＂） of the estimated turbulent fluxes. The analysis results showed that the LAS-derived turbulent fluxes for the highly heterogeneous urban area revealed reasonable temporal variation during daytime on clear days, in comparison to the land-surface process-resolving numerical modeling. A series of sensitivity tests indicated that the overall uncertainty in the LAS-derived daytime QH was within 20%-30% in terms of the influence of input parameters and the non- dimensional similarity function for the temperature structure function parameter, while the estimation errors in z were less sensitive to the factors of influence, except aerodynamic roughness length. The 3D LAS footprint modeling characterized the source areas of the LAS-derived turbulent fluxes in the heterogeneous urban area, revealing that the representative spatial scales of the LAS system deployed with the 2.1 km optical path distance ranged from 0.2 to 2 km2 （a ＂micro-a scale＂）, depending on local meteorological conditions.

关键词： heterogeneous surface large aperture scintillometer mesoscale modeling surface energy balance turbulentexchange

Efficient photovoltaic effect in graphene/h-BN/silicon heterostructure self-powered photodetector

在线全文

学校读者我要写书评

暂无评论

Nano Research 2021年第6期14卷 1967-1972页

作者： Ui Yeon Won Boo Heung lee young Rae Kim Won Tae Kang Ilmin lee Ji Eun Kim young Hee lee Woo Jong Yu Department of Electrical and Computer Engineering Sungkyunkwan UniversitySuwon16419Republic of Korea Center for Integrated Nanostructure Physics Institute for Basic Science(IBS)Suwon16419Republic of Korea

Graphene(Gr)/Si-based optoelectronic devices have attracted a lot of academic attention due to the simpler fabrication processes,low costs,and higher performance of their two-dimensional(2D)/three-dimensional(3D)hybrid interfaces in Schottky junction that promotes electron-hole ***,due to the built-in potential of Gr/Si as a photodetector,the Iph/Idark ratio is often hindered near zero-bias at relatively low illumination *** is a major drawback in self-powered *** this study,we have demonstrated a self-powered van der Waals heterostructure photodetector in the visible range using a Gr/hexagonal boron nitride(h-BN)/Si structure and clarified that the thin h-BN insertion can engineer asymmetric carrier transport and avoid interlayer coupling at the *** dark current was able to be suppressed by inserting an h-BN insulator layer,while maintaining the photocurrent with minimal decrease at near *** a result,the normalized photocurrent-to-dark ratio(NPDR)is improved more than 104 ***,both Iph/Idark ratio and detectivity,increase by more than 104 times at−0.03 V drain *** proposed Gr/h-BN/Si heterostructure is able to contribute to the introduction of next-generation photodetectors and photovoltaic devices based on graphene or silicon.

关键词： graphene hexagonal boron nitride van der Waals heterostructure self-powered Research

DICE:An Effective Query Result Cache for Distributed Storage Systems

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Computer Science & Technology 2010年第5期25卷 933-944页

作者： Jun-Ki Min Member, A CM Mi-young lee School of Computer Science and Engineering Korea University of Technology and Education Byeongcheon-myeon Cheonan Chungnam 330-708 Korea Cloud Computing Research Department Electronics and Telecommunications Research Institute (ETRI) Daejeon 305-700 Korea

Due to the proliferation of Internet and Intranet,the distributed storage systems have received a lot of attention. These systems span a large number of machines and store huge amount of data for a lot of *** the distributed storage systems,a row can be directly accessed using a row *** concentrate on a problem of efficient processing of queries whose predicate is on a column but not a row *** this paper,we present a cache management technique,called DICE which maintains query results of range queries to support the next range *** accelerate the search time of the cached query results,we use modified Interval Ski *** addition,we devise a novel cache replacement policy since DICE maintains an interval rather than a data *** our cache replacement policy considers the properties of intervals,our proposed technique is more efficient than traditional buffer replacement *** experimental result demonstrates the efficiency of our proposed technique.

关键词： distributed system range query query caching Interval Skip List cache replacement

Combating Drug Resistance in Colorectal Cancer Using Herbal Medicines

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2021年第7期27卷 551-560页

作者： lee Ga-young lee Jin-Seok Son Chang-Gue lee Nam-Hun Department of Clinical Oncology Cheonan Korean Medicine Hospital of Daejeon UniversityCheonan31099Republic of Korea Liver&Immunology Research Center Dunsan Korean Medicine Hospital of Daejeon UniversityDaejeon35235Republic of Korea Department of Internal Medicine Graduated School of Korean MedicineUniversity of DaejeonDaejeon34520Republic of Korea

Colorectal cancer(CRC)is one of the most prevalent and lethal cancer types around the *** of the CRC patients are treated with chemotherapeutic drugs alone or ***,up to 90%of metastatic cancer patients experience the failure of treatment mostly because of the acquired drug resistance,which can be led to multidrug resistance(MDR).In this study,we reviewed the recent literature which studied potential CRC MDR reversal agents among herbal medicines(HMs).Among abundant HMs,6 single herbs,Andrographis paniculata,Salvia miltiorrhiza,Hedyotis diffusa,Sophora flavescens,Curcuma longa,Bufo gargarizans,and 2 formulae,Pien Tze Huang and Zhi Zhen Fang,were found to overcome CRC MDR by two or more different mechanisms,which could be a promising candidate in the development of new drugs for adjuvant CRC chemotherapy.

关键词： colorectal cancer drug resistance herbal medicine

Evaluation of early-age strains and stresses in roller-compacted concrete pavement

在线全文

学校读者我要写书评

暂无评论

Journal of Traffic and Transportation Engineering(English Edition) 2022年第1期9卷 93-105页

作者： Tetsya Sok young Kyu Kim Jun young Park Seung Woo lee Public Infrastructure Department Ministry of Public Works and TransportPhnom Penh 12100Cambodia Institute for Disaster Prevention Gangneung-Wonju National UniversityGangneung-si 25457South Korea Korea Expressway Research Institute Korea Expressway CorporationHwaseong-si 18489South Korea Civil Engineering Department Gangneung-Wonju National UniversityGangneung-si 25457South Korea

In the structural design of a roller-compacted concrete pavement(RCCP), it is crucial to estimate strain and stress developments in the RCCP slab realistically. Since the RCCP mix uses less cement and lower amount of water, shrinkage strain and concrete temperature during the hardening stage are expected to be reduced as compared to those of conventional concrete mixture, resulting in a reduction of the concrete early-age deformation and stress developments in the RCCP slab. In this paper, early-age concrete strain and stress developments in RCCP slab subjected to environmental loads were evaluated. A full-scale test section of RCCP under real climatic conditions was monitored. The early-age total strains,stress-independent strains, shrinkage strains, and coefficient of thermal expansion(CTE) of the RCCP were measured and analyzed. Using the results of measured strains, in-situ CTE and shrinkage strain, and temperature, the early-age concrete stress development is computed by incorporating a viscoelastic property of the early-age concrete. The results revealed that the shrinkage strain of the RCCP is quite low as compared to that of conventional concrete. The early-age stress developments in the RCCP slab are strongly governed by the thermal-induced stresses. Shrinkage-induced stresses were quite small and might be negligible in a preliminary estimation of early-age stress developments in the RCCP slab.

关键词： Road engineering Roller-compacted concrete pavement Concrete strain Concrete stress Shrinkage strain Environmental loads

Electron beam deposition and characterization of thin film Ti-Ni for shape memory applications

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2006年第Z2期25卷 237-242页

作者： NOH Hae-Yong JEE Kwang-Koo lee Kyu-Hwan lee young-Kook Department of Metallurgical System Yonsei University Seoul 120-749 KoreaAdvanced Materials Research Center Division of Materials Korea Institute of Science and Technology Cheongryang Seoul 130-650 Korea Advanced Materials Research Center Division of Materials Korea Institute of Science and Technology Cheongryang Seoul 130-650 Korea Department of Metallurgical System Yonsei University Seoul 120-749 Korea

Thin film of Ti-Ni alloy has a potential to perform the microactuation functions required in the microelectromechanical system (MEMS). It is essential, however, to have good uniformity in both chemical composition and thickness to realize its full potential as an active component of MEMS devices. Electron beam evaporation technique was employed in this study to fabricate the thin films of Ti-Ni alloy on different substrates. The targets used for the evaporation were first prepared by electron beam melting. The uniformity of composition and microstructure of the thin films were characterized by electron probe microanalysis (EPMA), Auger electron spectroscopy (AES), X-ray diffraction (XRD), scanning electron microscopy (SEM), atomic force microscopy (AFM) and transmission electron microscopy (TEM). The mechanical property of the thin films was evaluated by the nano-indentation test. The martensitic transformation temperature was measured by differential scanning calorimetry (DSC). It is confirmed that the chemical composition of deposited thin films is identical to that of the target materials. Furthermore, results from depth profiling of the chemical composition variation reveal that the electron beam evaporation process yields better compositional homogeneity than other conventional methods such as sputtering and thermal evaporation. Microstructural observation by TEM shows that nanometer size precipitates are preferentially distributed along the grain boundaries of a few micron size grains. The hardness and elastic modulus of thin films decreases with an increase in Ti contents.

关键词： electron beam evaporation TiNi SMA thin film martensitic transformation reverse martensitic transformation