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Differential diagnosis of left-sided abdominal pain:Primary epiploic appendagitis vs colonic diverticulitis

World Journal of Gastroenterology 2013年第40期19卷 6842-6848页

作者： Jeong Ah Hwang Sun Moon Kim Hyun Jung Song Yu Mi Lee Kyung Min Moon Chang Gi Moon Hoon Sup Koo Kyung Ho Song Yong Seok Kim Tae Hee Lee Kyu Chan Huh young woo Choi young woo kang woo Suk Chung Division of Gastroenterology and Hepatology Department of Internal MedicineKonyang University College of MedicineDaejeon 302-718South Korea Department of Diagnostic Radiology Konyang University College of MedicineDaejeon 302-718South Korea

AIM:To investigate the clinical characteristics of left primary epiploic appendagitis and to compare them with those of left colonic ***:We retrospectively reviewed the clinical records and radiologic images of the patients who presented with left-sided acute abdominal pain and had computer tomography(CT) performed at the time of presentation showing radiological signs of left primary epiploic appendagitis(PEA) or left acute colonic diverticulitis(ACD) between January 2001 and December 2011. A total of 53 consecutive patients were enrolled and evaluated. We also compared the clinical characteristics,laboratory findings,treatments,and clinical results of left PEA with those of left ***:Twenty-eight patients and twenty-five patients were diagnosed with symptomatic left PEA and ACD,respectively. The patients with left PEA had focal abdominal tenderness on the left lower quadrant(82.1%). On CT examination,most(89.3%) of the patients with left PEA were found to have an oval fatty mass with a hyperattenuated ring sign. In cases of left ACD,the patients presented with a more diffuse abdominal tenderness throughout the left side(52.0%vs 14.3%; P = 0.003). The patients with left ACD had fever and rebound tenderness more often than those with left PEA(40.0% vs 7.1%,P = 0.004; 52.0% vs14.3%,P = 0.003,respectively). Laboratory abnormalities such as leukocytosis were also more frequently observed in left ACD(52.0% vs 15.4%,P = 0.006).CONCLUSION:If patients have left-sided localized abdominal pain without associated symptoms or laboratory abnormalities,clinicians should suspect the diagnosis of PEA and consider a CT scan.

关键词： Acute abdomen Differential diagnosis Appendix epiploica Colonic diverticulitis Multidetector computed tomography

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Safety and efficacy of tenofovir in chronic hepatitis B-related decompensated cirrhosis

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World Journal of Gastroenterology 2017年第13期23卷 2396-2403页

作者： Soon Kyu Lee Myeong Jun Song Seok Hyun Kim Byung Seok Lee Tae Hee Lee young woo kang Suk Bae Kim Il Han Song Hee Bok Chae Soon young Ko Jae Dong Lee Division of Hepatology Department of Internal MedicineDaejeon St.Mary's HospitalCollege of MedicineThe Catholic University of Korea Department of Internal Medicine Chungnam University Hospital Department of Internal Medicine Konyang University Hospital Department of Internal Medicine Dankook University Hospital Department of Internal Medicine Chung Buk University Hospital Department of Internal Medicine Konkuk University Chungju Hospital

AIM To evaluate the safety and efficacy of tenofovir disoproxil fumarate(TDF) as a first-line therapy in decompensated liver disease. METHODS We enrolled 174 chronic hepatitis B-related liver cirrhosis patients treated with 300 mg/d TDF at six Korean centers. Of the 174 cirrhosis patients, 57 were assigned to the decompensated cirrhosis group and 117 were assigned to the compensated cirrhosis group. We followed the patients for 12 mo and evaluated clinical outcomes, including biochemical, virological, and serological responses. We also evaluated changes in hepatic and renal function and compared the decompensated and compensated cirrhosis groups. RESULTS The 1-year complete virological response(CVR) and Hepatitis B e antigen(HBe Ag) seroconversion were seen in 70.2% and 14.2% in the decompensated cirrhosis group, respectively. The rates of HBe Ag seroconversion/loss and ALT normalization at month 12 were similar in both groups. TDF treatment was also effective for decreasing the level of hepatitis B virus(HBV) DNA in both groups, but CVR was higher in the compensated group(88.9% vs 70.2%, P = 0.005). Tenofovir treatment for 12 mo resulted in improved Child-Turcotte-Pugh(CTP) and model for end-stage liver disease(MELD) scores in decompensated group(P < 0.001). Of the 57 decompensated patients, 39(68.4%) achieved CTP class A and 27(49.1%) showed improvement in the CTP score of 2 points after 12 mo of TDF. The observed rate of confirmed 0.5 mg/d L increases in serum levels of creatinine in the decompensated and compensated cirrhosis group were 7.0% and 2.5%, respectively(P < 1.000).CONCLUSION TDF therapy in decompensated cirrhosis patients was effective for decreasing HBV DNA levels and improving hepatic function with relatively lower CVR than in compensated cirrhosis. Thus, physicians should carefully monitor not only renal function but also treatment responses when using TDF in decompensated cirrhosis patients.

关键词： Tenofovir Decompensated liver cirrhosis Compensated liver cirrhosis Virological response Renal safety

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Long-term treatment outcomes of clevudine in antiviral-naive patients with chronic hepatitis B

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World Journal of Gastroenterology 2012年第47期18卷 6943-6950页

作者： Suk Bae Kim Il Han Song young Min Kim Ran Noh Ha Yan kang Hyang Ie Lee Hyeon Yoong Yang An Na Kim Hee Bok Chae Sae Hwan Lee Hong Soo Kim Tae Hee Lee young woo kang Eaum Seok Lee Seok Hyun Kim Byung Seok Lee Heon young Lee Department of Internal Medicine Dankook University College of MedicineCheonan 330-715South Korea Department of Internal Medicine Eulji University College of MedicineDaejeon 302-779South Korea Department of Internal Medicine Chungbuk University College of MedicineCheongju 362-711South Korea Department of Internal Medicine Soonchunhyang University College of MedicineCheonan 330-090South Korea Department of Internal Medicine Konyang University College of MedicineDaejeon 371-718South Korea Department of Internal Medicine Chungnam University College of MedicineDaejeon 301-721South Korea

AIM:To evaluate the treatment outcomes of clevudine compared with entecavir in antiviral-naive patients with chronic hepatitis B(CHB).METHODS:We retrospectively analyzed the clinical data of CHB patients treated with clevudine 30 mg/d and compared their clinical outcomes with patients treated with entecavir 0.5 mg/*** biochemical response,as assessed by serum alanine aminotransferase(ALT) activity,virologic response,as assessed by serum hepatitis B virus DNA(HBV DNA) titer,serologic response,as assessed by hepatitis B e antigen(HBeAg) status,and virologic breakthrough with genotypic mutations were ***:Two-hundred and fifty-four patients [clevudine(n = 118) vs entecavir(n = 136)] were *** clevudine-treated patients,the cumulative rates of serum ALT normalization were 83.9% at week 48 and 91.5% at week 96(80.9% and 91.2% in the entecavir group,respectively),the mean titer changes in serum HBV DNA were-6.03 and-6.55 log 10 copies/mL(-6.35 and-6.86 log 10 copies/mL,respectively,in the entecavir group),and the cumulative non-detection rates of serum HBV DNA were 72.6% and 83.1%(74.4% and 83.8%,respectively,in the entecavir group).These results were similar to those of entecavir-treated *** cumulative rates of HBeAg seroconversion were 21.8% at week 48 and 25.0% at week 96 in patients treated with clevudine,which was similar to patients treated with entecavir(22.8% and 27.7%,respectively).The virologic breakthrough in the clevudine group occurred in 9(7.6%) patients at weeks 48 and 15(12.7%) patients at week 96,which primarily corresponded to genotypic mutations of rtM204I and/or *** was no virologic breakthrough in the entecavir ***:In antiviral-naive CHB patients,longterm treatment outcomes of clevudine were not inferior to those of entecavir,except for virologic breakthrough.

关键词： Chronic hepatitis B Hepatitis B virus Clevudine Entecavir Treatment outcomes

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Effective parameters on diameter of carbon nanotubes by plasma enhanced chemical vapor deposition

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中国有色金属学会会刊：英文版 2012年第S3期22卷 712-716页

作者： kang young JEONG Hyun Kyung JUNG Hyung woo LEE National Core Research Center for Hybrid Materials Solution Hybrid Graduate SchoolPusan National University Department of Diagnostic Radiology Inje University College of MedicineHaeundae Paik Hospital

The effective parameters on the diameter of carbon nanotubes (CNTs) by plasma enhanced chemical vapor deposition (PECVD) were *** lots of influential parameters,the effects of the catalytic film thickness and the pretreatment plasma power on the growth of CNTs were *** results show that the size of catalytic islands increases by increasing the thickness of catalytic layer,but the density of CNTs *** pretreatment duration time of 30 s is the optimal condition for growing CNTs with about 50 nm in *** increasing the pretreatment plasma power,the diameter of CNTs decreases ***,the diameter of CNTs does not change drastically from 80 to 120 *** uniformly grown CNTs with the diameter of 50 nm are obtained at the pretreatment plasma power of 100 W.

关键词： carbon nanotubes catalytic film thickness pretreatment plasma power plasma enhanced chemical vapor deposition

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Production of high-purity Mg metal from dolomite through novel molten salt electrolysis and vacuum distillation

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Journal of Magnesium and Alloys 2023年第4期11卷 1308-1320页

作者： Hyeong-Jun Jeoung Tae-Hyuk Lee Jin-young Lee Kyung-woo Yi Jungshin kang Korea Institute of Geoscience and Mineral Resources 124 Gwahak-ro Yuseong-guDaejeon 34132Republic of Korea Department of Materials Science and Engineering Seoul National University1 Gwanak-roGwanak-guSeoul 08826Republic of Korea Department of Resources Engineering University of Science and Technology217 Gajeong-ro Yuseong-guDaejeon 34113Republic of Korea School of Materials Science and Engineering Pusan National University2 Busandaehak-roGeumjeong-guBusan 46241Republic of Korea

In this study,a novel Mg production process for producing high-purity Mg metal from dolomite was *** the electrolysis of calcined dolomite was conducted using Cu cathode and C anode in MgF_(2)–LiF molten salt at 1083–1173 K by applying an average current of 1.42–1.46 A for 9.50–21.0 h,the current efficiency of 66.4–88.6%was *** produced Mg alloys consisted of MgCu_(2)and Cu(Mg)or MgCu_(2)and CuMg_(2)phases,depending on the Mg concentration in the Mg *** the electrolysis of calcined dolomite was conducted in MgF_(2)–LiF–CaF_(2)molten salt at 1083 K,the current efficiency was 40.9–71.4%,owing to undesired reactions such as electroreduction of Ca^(2+)or/and CO_(3)^(2−)***,the current efficiency increased from 40.9%to 63.2%by utilizing a Pt anode,because the occurrence of CO_(3)^(2−)ions in the molten salt was *** vacuum distillation of the obtained Mg alloys at 1300 K for 10 h,Mg metal with a purity of 99.9996–99.9998%was ***,the feasibility of this novel process for the production of high-purity Mg metal from dolomite was demonstrated.

关键词： High-purity magnesium Dolomite Magnesium oxide Electrolytic process Copper metal cathode Vacuum distillation

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Recovery of cerium from glass polishing slurry

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Journal of Rare Earths 2011年第11期29卷 1075-1078页

作者： Jong-young Kim Ung-Soo Kim Myeong-Seop Byeon woo-Kyu kang Kwang-Teak Hwang woo-Seok Cho Icheon Branch Korea Institute of Ceramic Engineering and TechnologyGyeongchung Rd.Sindun-MyeonIcheon-siKyeonggi-do 467-843Korea RANCO Cheongju-siChungcheongbuk-doKorea

Cerium was extracted from rare earth slurry waste used for polishing a glass ***,glass frit and flocculant were removed by froth flotation and *** recovered rare earth slurry exhibited almost the same particle size distribution as original slurry,which could be reused as slurry for glass *** the rare earth slurry,the cerium solution was obtained by an oxidative thermal treatment and subsequent chemical *** cerium solution was further purified up to 94% by selective precipitation of rare earth species.

关键词： cerium separation waste polishing slurry rare earths

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Dielectrophoretic assembly of semiconducting single-walled carbon nanotube transistor

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Transactions of Nonferrous Metals Society of China 2011年第A01期21卷 126-129页

作者： Se-Hun KWON young-Keun JEONG Soongeun KWON Myung-Chang kang Hyung-woo LEE National Core Research Center for Hybrid Materials Solution Pusan National University Department of Mechanical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 305-701 Korea

A novel burning technique for making a semiconducting single-walled carbon nanotubes （SWNTs） transistor assembled by the dielectrophoretic force was suggested. The fabrication process consisted of two steps. First, to align and attach a bundle of SWNTs between the source and drain, the alternating （AC） voltage was applied to the electrodes. When a bundle of SWNTs was connected between two electrodes, some of metallic nanotubes and semi-conducing nanotubes existed together. The second step is to burn the metallic SWNTS by applying the voltage between two electrodes. With increasing the voltage, more current flowed through the metallic SWNTs, thus, the metallic SWNTs burnt earlier than the semiconducting one. This technique enables to obtain only semi-conducting SWNTs connection in the transistor. Through the 1--V characteristic graph, the moment of metallic SWNTs burning and the characteristic of semi-conducing nanotubes were verified.

关键词： single-walled carbon nanotube (SWNT) semi-conducting carbon nanotube burning technique dielectrophoresis

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Use of various MgO resources for high-purity Mg metal production through molten salt electrolysis and vacuum distillation

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Journal of Magnesium and Alloys 2023年第2期11卷 562-579页

作者： Hyeong-Jun Jeoung Tae-Hyuk Lee youngjae Kim Jin-young Lee young Min Kim Toru HOkabe Kyung-woo Yi Jungshin kang Korea Institute of Geoscience and Mineral Resources 124 Gwahak-ro Yuseong-guDaejeon 34132South Korea Department of Materials Science and Engineering Seoul National University1 Gwanak-roGwanak-guSeoul 08826South Korea Department of Resources Engineering University of Science and Technology217 Gajeong-ro Yuseong-guDaejeon 34113South Korea Korea Institute of Materials Science 797 Changwondae-roSeongsan-guChangwonGyeongnam 51508South Korea Institute of Industrial Science The University of Tokyo4-6-1 KomabaMeguro-kuTokyo 153-8505Japan School of Materials Science and Engineering Pusan National University2 Busandaehak-roGeumjeong-guBusan 44241South Korea

A green and effective electrolytic process was developed to produce high-purity Mg metal using primary and secondary resources containing Mg O as a feedstock. The electrolysis of various Mg O resources was conducted using a Cu cathode in MgF2– LiF – KCl molten salt at 1043 K by applying an average current of 1.44 A for 12.5 h. The electrolysis of calcined North Korean magnesite and seawater Mg O clinker yielded Mg alloys of MgCu2and(Cu) phases with current efficiencies of 89.6–92.4%. The electrolysis of oxidized Mg O-C refractory brick, aged ferronickel slag, and ferronickel slag yielded Mg alloys of MgCu2and(Cu) phases with current efficiencies of 59.3–92.3%. The vacuum distillation of Mg alloys obtained was conducted at 1300 K for 10 h to produce high-purity Mg metal. After vacuum distillation, Mg metal with a purity of above 99.994% was obtained. Therefore, this study demonstrates the feasibility of the production of high-purity Mg metal from various Mg O resources using a novel electrolytic process with a Cu cathode, followed by vacuum distillation.

关键词： High-purity magnesium Magnesium oxide resources Electrolytic process Metal cathode Vacuum distillation

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Efficient photovoltaic effect in graphene/h-BN/silicon heterostructure self-powered photodetector

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Nano Research 2021年第6期14卷 1967-1972页

作者： Ui Yeon Won Boo Heung Lee young Rae Kim Won Tae kang Ilmin Lee Ji Eun Kim young Hee Lee woo Jong Yu Department of Electrical and Computer Engineering Sungkyunkwan UniversitySuwon16419Republic of Korea Center for Integrated Nanostructure Physics Institute for Basic Science(IBS)Suwon16419Republic of Korea

Graphene(Gr)/Si-based optoelectronic devices have attracted a lot of academic attention due to the simpler fabrication processes,low costs,and higher performance of their two-dimensional(2D)/three-dimensional(3D)hybrid interfaces in Schottky junction that promotes electron-hole ***,due to the built-in potential of Gr/Si as a photodetector,the Iph/Idark ratio is often hindered near zero-bias at relatively low illumination *** is a major drawback in self-powered *** this study,we have demonstrated a self-powered van der Waals heterostructure photodetector in the visible range using a Gr/hexagonal boron nitride(h-BN)/Si structure and clarified that the thin h-BN insertion can engineer asymmetric carrier transport and avoid interlayer coupling at the *** dark current was able to be suppressed by inserting an h-BN insulator layer,while maintaining the photocurrent with minimal decrease at near *** a result,the normalized photocurrent-to-dark ratio(NPDR)is improved more than 104 ***,both Iph/Idark ratio and detectivity,increase by more than 104 times at−0.03 V drain *** proposed Gr/h-BN/Si heterostructure is able to contribute to the introduction of next-generation photodetectors and photovoltaic devices based on graphene or silicon.

关键词： graphene hexagonal boron nitride van der Waals heterostructure self-powered Research

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Germinant ZnO nanorods as a charge-selective layer in organic solar cells

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Journal of Materials Science & Technology 2020年第20期52卷 89-94页

作者： Kunsik An Jaehoon Kim Mohammad Afsar Uddin Seunghyun Rhee Hyeok Kim Kyung-Tae kang Han young woo Changhee Lee Department of Electrical and Computer Engineering Seoul National UniversitySeoul 08826Republic of Korea Micro/Nano Process Group Korea Institute of Industrial Technology(KITECH)Sangnok-guAnsan-si 15588Republic of Korea Department of Chemistry College of ScienceKorea UniversitySeoul 02841Republic of Korea Department of Electrical Engineering Engineering Research Institute(ERI)Gyeongsang National UniversityJinju 52828Republic of Korea

A facile method was introduced and demonstrated to synthesize zinc oxide(ZnO) nanorods(NRs) as an electron transporting layer(ETL) for organic solar cells(OSCs).Hydrothermal synthesis of the NRs showed a constant growth rate of 5.5 nm min-1 from germination to sub-micrometer *** properties were characterized using scanning electron microscopy(SEM),transmission electron microscopy(TEM),absorption spectrophotometry and so *** on these measurements,the germinant growth mechanism and its corresponding orientation characteristics were *** an ETL of the OSCs,ZnO NRs enhance the charge extraction from the active layer due to their increased interfacial surface area,but there is an optimal length because of the shunt path formation and UV absorption of long ZnO *** a re sult,the OSC with the ZnO NRs as ETL shows power conversion efficiency(PCE) up to 6.2%.The J-V characteristics and incident photon-to-current conversion efficiency(IPCE) measurement also reveal that the efficiency enhancement is an assembly of individual results from optical,physical and electrical characteristic of the ZnO NRs.

关键词： ZnO nanorods Solar cells Self-assembly Oriented growth mechanism Hydrothermal synthesis

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