检索结果-南通市图书馆

云南省汉族中所见的一例G6PD基因nt1004C→A突变

在线全文

学校读者我要写书评

暂无评论

中华血液学杂志 1997年第10期18卷 535-537页

作者：杜传书何永蜀中山医科大学医学遗传教研室昆明医学院

目的：检测云南人群中是否存在新的葡萄糖－６－磷酸脱氢酶（Ｇ６ＰＤ）基因突变型。方法：在排除中国人中的常见突变后，作２～１２逐个外显子多聚酶链反应－单链构象多态性（ＰＣＲ－ＳＳＣＰ）分析，对电泳异常者测序证实。结果：在... 详细信息

目的：检测云南人群中是否存在新的葡萄糖－６－磷酸脱氢酶（Ｇ６ＰＤ）基因突变型。方法：在排除中国人中的常见突变后，作２～１２逐个外显子多聚酶链反应－单链构象多态性（ＰＣＲ－ＳＳＣＰ）分析，对电泳异常者测序证实。结果：在筛查云南人群８２３人Ｇ６ＰＤ缺乏症时，发现Ｇ６ＰＤ缺乏者５４例。对其中２９例作了突变型鉴定，除发现１３８８Ｇ→Ａ突变１９例、１３８１Ｇ→Ａ突变１例外，其余９例中，查出１例为第９外显子ＳＳＣＰ有异常泳带。直接测序证实在第９外显子ｎｔ１００４位有Ｃ→Ａ的碱基置换，导致丙氨酸→天冬氨酸。结论：该例为罕见突变，为中国人中的第二例，云南汉族中的首例。

关键词： G6PD缺乏基因突变聚合酶链反应云南

A novel fluorescent probe for volatile amine vapor detection

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第3期35卷 3-4页

作者： Lulu Bu Daofu Liu Longde Wang Mei Sun Chao Gao yongshu Xie School of Chemistry and Materials Engineering Anhui Province Key Laboratory of Low Temperature Co-Fired MaterialsHuainan Normal UniversityHuainan 232038China College of Material Chemistry and Chemical EngineeringKey Laboratory of Organosilicon Chemistry and Material Technology of Ministry of EducationHangzhou Normal UniversityHangzhou 311121China Shanghai Key Laboratory of Functional Materials Chemistry Key Laboratory for Advanced Materials and Institute of Fine ChemicalsSchool of Chemistry&Molecular EngineeringEast China University of Science&TechnologyShanghai 200237China

In recent years,fluorescent probes have gained significant prominence in the field of substance analysis and detection[1–4].The development of high-performance volatile amine gas sensors is crucial for applications i... 详细信息

关键词： volatile gained probe

Solar cells based on doubly concerted companion dyes with the efficiencies modulated by inserting an ethynyl group at different positions

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第5期35卷 189-192页

作者： Yuqing Wang Zhemin Li Qingjun Lu Qizhao Li Jiaxin Luo Chengjie Li yongshu Xie Key Laboratory for Advanced Materials Frontiers Science Center for Materiobiology and Dynamic ChemistryInstitute of Fine ChemicalsSchool of Chemistry and Molecular EngineeringEast China University of Science&TechnologyShanghai 200237China

To develop efficient sensitizers for dye-sensitized solar cells(DSSCs),we recently reported doubly concerted companion(DCC)dye XW83 with a wrapped porphyrin sub-dye unit linked to an organic sub-dye unit through a flexible chain,which exhibits panchromatic absorption and excellent anti-aggregation *** further improve the absorption,we herein report XW87 and XW88 by inserting an ethynyl group into the organic sub-dye unit of XW83 near the donor and acceptor,*** the corresponding organic dyes Z3 and Z4,the introduced ethynyl group improves their absorption,but induces aggravated charge recombination,leading to lowered power conversion efficiencies(PCEs).Similar to the organic dyes,the introduced ethynyl group improves the absorption of DCC dyes XW87 and XW88 as *** addition,the ethynyl group near the acceptor of the organic sub-dye unit can be well protected by the long wrapping chains from the porphyrin *** a result,XW88 affords the highest JSC(21.84 mA/cm^(2)),V_(OC)(782 mV)and PCE(12.2%)among the DCC *** results provide an effective method for developing efficient DSSC dyes by inserting an ethynyl group at a suitable position of a DCC dye.

关键词： Porphyrin Ethynyl bridge Charge-recombination Dye sensitized solar cells Doubly concerted companion dyes

在线全文

学校读者我要写书评

暂无评论

基于BP神经网络模型的故障预测分析

微计算机信息 2006年第6S期22卷 220-222,6页

作者：何勇枢陈赣广东省东莞市麻涌镇新基工业区麻涌供电公司麻涌供电公司

本文以数据采集与监控(SCADA)系统提供数据和设备故障的历史数据作为故障预测的数据来源,对动态数据和静态数据采用BP神经网络建模,测试结果说明了模型的有效性。

关键词：故障预测神经网络 SCADA系统数据采集

云南省几个民族葡萄糖-6-磷酸脱氢酶基因突变型分析

在线全文

学校读者我要写书评

暂无评论

中华血液学杂志 1997年第4期18卷 193-196页

作者：何永蜀杜传书蒋纬莹王国燕任晓琴中山医科大学医学遗传研究室昆明医学院

目的：分析云南籍汉族及少数民族葡萄糖－６－磷酸脱氢酶（Ｇ６ＰＤ）缺乏症患者的Ｇ６ＰＤ基因突变。方法：应用自然引物或“错配引物”介导的多聚酶链反应限制性酶切分析方法，分析２９例云南籍几个民族Ｇ６ＰＤ缺乏症患者Ｇ６ＰＤ基... 详细信息

目的：分析云南籍汉族及少数民族葡萄糖－６－磷酸脱氢酶（Ｇ６ＰＤ）缺乏症患者的Ｇ６ＰＤ基因突变。方法：应用自然引物或“错配引物”介导的多聚酶链反应限制性酶切分析方法，分析２９例云南籍几个民族Ｇ６ＰＤ缺乏症患者Ｇ６ＰＤ基因突变型。结果：发现１３８８突变１９例，１３７６突变１例，未定型９例。２９例标本中有７例为少数民族，分别为彝族３例（１３８８突变）、白族２例（１３８８突变）、傣族１例（１３８８突变）、纳西族１例（１３８８突变）。除傣族外，在其余三个少数民族中检出Ｇ６ＰＤ基因１３８８突变在国内尚属首次。结论：这种突变的发生早于少数民族形成之前，并可推测云南省Ｇ６ＰＤ缺乏症患者中Ｇ６ＰＤ基因突变型分布比例，有助于了解分子进化进程。

关键词：葡萄糖磷酸脱氢酶遗传性酶病 G6PD 基因突变

Spin switching in corrole radical complex

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第1期35卷 1-2页

作者： Chunyan Yu Hongping Xiao Hua Lu yongshu Xie College of Material Chemistry and Chemical EngineeringKey Laboratory of Organosilicon Chemistry and Material Technology of Ministry of EducationHangzhou Normal UniversityHangzhou 311121China College of Chemistry and Materials Engineering Wenzhou UniversityWenzhou 325035China Functional Materials Chemistry Key Laboratory for Advanced Materials and Institute of Fine ChemicalsSchool of Chemistry&Molecular EngineeringEast China University of Science&TechnologyShanghai 200237China

Spintronics is a cutting-edge field of developing new electronic devices by manipulating the electron spin and magnetic moment[1].Traditional spintronic research mainly focuses on transition metals and inorganic semiconductors,while organic molecules have the advantage of being extremely easy to realize efficient spin control by modifying the specific external conditions for desired electronic structures and magnetic ***,as a ring-contracted porphyrin,is the aromatic analog of the central macrocycle of vitamin *** has a squeezed inner cavity and three inner NHs in its free-base form,making it easier to stabilize high-valent metal ions and thus a promising candidate in spintronics.

关键词： Corrole inner radical

云南省彝族三种常见葡萄糖-6-磷酸脱氢酶基因突变型分析

在线全文

学校读者我要写书评

暂无评论

中华血液学杂志 1999年第4期20卷 194-196页

作者：何永蜀陈乔张志莲王国燕杜传书中山医科大学医学遗传学研究室昆明医学院云南省永仁县人民医院

目的分析云南籍彝族葡萄糖６磷酸脱氢酶（Ｇ６ＰＤ）缺乏症患者三种常见基因突变型。方法应用突变特异性扩增系统（ＡＲＭＳ）分析２８例云南籍彝族Ｇ６ＰＤ缺乏症患者Ｇ６ＰＤ基因突变类型。结果发现１３８８（Ｇ→Ａ）突变１２例... 详细信息

目的分析云南籍彝族葡萄糖６磷酸脱氢酶（Ｇ６ＰＤ）缺乏症患者三种常见基因突变型。方法应用突变特异性扩增系统（ＡＲＭＳ）分析２８例云南籍彝族Ｇ６ＰＤ缺乏症患者Ｇ６ＰＤ基因突变类型。结果发现１３８８（Ｇ→Ａ）突变１２例，１３７６（Ｇ→Ｔ）突变９例，９５（Ａ→Ｇ）突变１例，未定型６例。结论在彝族人群中检出１３７６和９５突变在国内尚属首次。上述三种突变在２８例彝族Ｇ６ＰＤ缺乏症患者中占７８６％，且也为汉族中的常见突变，结果提示汉族和彝族可能源于同一祖先，云南省彝族的形成可能是在Ｇ６ＰＤ基因常见突变产生之后，为研究彝族的起源提供了分子遗传学资料。

关键词： G6PD缺乏基因扩增基因突变

The 2^(nd)Asian Conference on Porphyrins,Phthalocyanines and Related Materials

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第7期35卷 1-3页

作者： Gaojie Zhu Zhen Yang Shijun Li Weihua Zhu Rui Cao Junlong Zhang Jianzhang Zhao Jonathan L.Sessler Xunjin Zhu Jianxin Song yongshu Xie Jianzhuang Jiang Key Laboratory for Advanced Materials and Institute of Fine Chemicals School of Chemistry and Molecular EngineeringEast China University of Science&TechnologyShanghai 200237China College of Material Chemistry and Chemical EngineeringKey Laboratory of Organosilicon Chemistry and Material Technology of Ministry of EducationHangzhou Normal UniversityHangzhou 311121China School of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang 212013China Key Laboratory of Applied Surface and Colloid Chemistry Ministry of EducationSchool of Chemistry and Chemical EngineeringShaanxi Normal UniversityXi'an 710119China Beijing National Laboratory for Molecular Sciences State Key Laboratory of Rare Earth Materials Chemistry and ApplicationsCollege of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China State Key Laboratory of Fine Chemicals Frontier Science Center for Smart MaterialsSchool of Chemical EngineeringDalian University of TechnologyDalian 116024China Department of Chemistry The University of TexasAustinTexas 78712-1224United States Department of Chemistry and Institute of Advanced Materials Hong Kong Baptist UniversityHong Kong 999077China Key Laboratory of Chemical Biology and Traditional Chinese Medicine(Ministry of Educational of China) Key Laboratory of the Assembly and Application of Organic Functional Molecules of Hunan ProvinceCollege of Chemistry and Chemical EngineeringHunan Normal UniversityChangsha 410081China Beijing Advanced Innovation Center for Materials Genome Engineering Beijing Key Laboratory for Science and Application of Functional Molecular and Crystalline MaterialsDepartment of Chemistry and Chemical EngineeringSchool of Chemistry and Biological EngineeringUniversity of Science and Technology BeijingBeijing 100083China

In the past decades,porphyrins,phthalocyanines and related materials have attracted significant attention due to their diverse and brilliant structures[1,2],as well as their unique electronic structures and photophysi... 详细信息

关键词： cyanine phthalocyanine Porphyrin

在线全文

学校读者我要写书评

暂无评论

异常血红蛋白E与疟疾的相互关系研究进展

国际遗传学杂志 2018年第4期41卷 300-304+322页

作者：邓泽帅李宏何永蜀昆明医科大学细胞生物学与医学遗传学系

异常血红蛋白E(hemoglobin E,HbE)是由于β珠蛋白基因发生点突变,氨基酸替代使血红蛋白性质和功能发生改变而引起的血液遗传病,属于常染色体隐性遗传。疟疾是由于疟原虫感染而引起的传染病,是危害全球公共健康最严重的疾病之一。常见血... 详细信息

异常血红蛋白E(hemoglobin E,HbE)是由于β珠蛋白基因发生点突变,氨基酸替代使血红蛋白性质和功能发生改变而引起的血液遗传病,属于常染色体隐性遗传。疟疾是由于疟原虫感染而引起的传染病,是危害全球公共健康最严重的疾病之一。常见血红蛋白病和疟疾的地理分布大致吻合,表明两种疾病之间存在相互联系,但异常血红蛋白E与疟疾的相互关系尚有不同看法,HbE是否对疟疾抗性尚有争论。本文综合近年来血红蛋白E与疟疾的关系及对疟疾的抗性作用进行介绍。

关键词：异常血红蛋白E病疟疾抗性选择压力