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Assessment of the Tidal Current Energy Resources and the Hydrodynamic Impacts of Energy Extraction at the PuHu Channel in Zhoushan Archipelago,China

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Journal of Ocean University of China 2021年第3期20卷 478-488页

作者： WU He YU Huaming FANG yizhou ZHOU Qingwei ZHUO Fengxuan KELLY Ryan M. National Ocean Technology Center Tianjin 300112China College of Oceanic and Atmospheric Sciences Ocean University of ChinaQingdao 266100China Southern Marine Science and Engineering Guangdong Laboratory Zhuhai 519082China Rykell Scientific Editorial PlacentiaCA 92871USA

An unstructured model FVCOM(The Unstructured Grid Finite Volume Community Ocean Model)with sink momentum term was applied to simulate the tidal current field in Zhoushan Archipelago,China,with focus on the region named PuHu Channel between Putuo Island and Hulu *** model was ca.ibrated with several measurements in the channel,and the model perform-ance was *** examination of the spatial and temporal distributions of tidal energy resources based on the numerica. simula-tion revealed that the greatest power density of tidal energy during spring tide is 3.6kWm^(−2)at the northern area of the *** parameters were introduced to characterize the generation duration of the tidal array that ca.ses the temporal variation of tidal current *** annual average available energy in the channel was found to be approximately *** annual generating hours at rated power was found to be 1800 h when the installed ca.acity of tidal array is approximately 12MW.A site for the tidal array with 25 turbines was selected,and the layout of the array was configured based on the EMEC *** influence due to the deployment of the tidal array was simulated by the modified FVCOM *** simulation showed that the tidal level did not significa.tly change beca.se of the operation of the tidal *** velocity reduction covered a 2km^(2)area of the downstream the tidal array,with a maximum velocity reduction of 8cms−1 at mid-flood tide,whereas the streamwise velocity on both sides of the farm increased slightly.

关键词： tidal current energy resources assessment numerica. simulation hydrodynamic effects

Genetic analysis and ca.didate gene identifica.ion of salt tolerancerelated traits in maize

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Journal of Integrative Agriculture 2024年第7期23卷 2196-2210页

作者： Hui Fang Xiuyi Fu Hanqiu Ge Mengxue Jia Jie Ji yizhou Zhao Zijian Qu Ziqian Cui Aixia Zhang Yuandong Wang Ping Li Baohua Wang Scientific Observing and Experimental Station of Maize in Plain Area of Southern Region Ministry of Agriculture and Rural Affairs/School of Life SciencesNantong UniversityNantong 226019China Maize Research Institute Beijing Academy of Agriculture and Forestry Sciences(BAAFS)Beijing 100097China

Soil salinization poses a threat to maize production worldwide,but the genetic mechanism of salt tolerance in maize is not well ***,identifying the genetic components underlying salt tolerance in maize is of great *** the current study,a teosinte-maize BC2F7 population was used to investigate the genetic basis of 21 salt tolerance-related *** total,125 QTLs were detected using a high-density genetic bin map,with one to five QTLs explaining 6.05–32.02%of the phenotypic variation for each *** total phenotypic variation explained(PVE)by all detected QTLs ranged from 6.84 to 63.88%for each *** all 125 QTLs,only three were major QTLs distributed in two genomic regions on chromosome 6,which were involved in three salt tolerance-related *** addition,10 pairs of epistatic QTLs with additive effects were detected for eight traits,explaining 0.9 to 4.44%of the phenotypic ***,18 QTL hotspots affecting 3–7 traits were *** one hotspot(L5),a gene cluster consisting of four genes(ZmNSA1,SAG6,ZmCLCg,and ZmHKT1;2)was found,suggesting the involvement of multiple pleiotropic ***,two important ca.didate genes,Zm00001d002090 and Zm00001d002391,were found to be associated with salt tolerance-related traits by a combination of linkage and marker-trait association ***00001d002090 encodes a ca.cium-dependent lipid-binding(ca.B domain)family protein,which may function as a ca.(2+)sensor for transmitting the salt stress signal downstream,while Zm00001d002391 encodes a ubiquitin-specific protease belonging to the C19-related *** findings provide valuable insights into the genetic basis of salt tolerance-related traits in maize and a theoretica. foundation for breeders to develop enhanced salt-tolerant maize varieties.

关键词： maize salt tolerance-related traits QTL mapping region-based association analysis

Effects of palmatine on potassium and ca.cium currents in isolated rat hepatocytes

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World Journal of Gastroenterology 2003年第2期9卷 329-333页

作者： FangWang Hong-yizhou LanCheng GangZhao JiZhou Li-YingFu Wei-XingYao DepartmentofPharmacology TongjiMedicalCollegeofHuazhongUniversityofScienceandTechnologyWuhan430030HubeiProvinceChina DepartmentofPancreaticSurgeryCenter UnionHospitalTongjiMedicalCollegeofHuazhongUniversityofScienceandTechnologyWuhan430022HubeiProvinceChina

AIM: To study the effects of palmatine, a known inhibitoron delayed rectifier potassium current and L-type ca.ciumcurrent (Ica.L) in guinea pig ventricular myocytes, on thepotassium and ca.cium currents in isolated rat ***: Tight-seal wh ole-cell patch-clamp techniqueswere performed to investigate the effects of palmatine onthe delayed outward potassium currents (IK), inward rectifierpotassium current (IK1) and ca.+ release-activated ca.+current (ICRAC) in enzymatica.ly isolated rat ***: Palmatine 0.3-100 μM reduced IK in a concentationdependent manner with EC50of 41.62±10.11 μM and nH,0.48±0.07 (n=8). The effect of the drug was poorly reversibleafter washout. When the bath solution was changed totetraethylammonium (TEA) 8 mM, IK was *** 10 μM and 100 μM shifted the I-V curves of IKdownward, and the block of IK was *** 0.3-100 μM also inhibited ICRAC in a concentration-dependent manner. The fitting parameters were as follows:ECs0=51.19±15.18 μM, and nH=0.46+0.07 (n=8). The peakvalue of ICRAC in the I-V relationship was decreased bypalmatine 10 μM and 100 μM. But the reverse potential ofIcRAcoCcurred at Voltage=0 mV in all cells. Palmatine 0.3-100 μM failed to have any significa.t effect on either inwardor outward components of IK1 at any membrane ***: The inhibitory effects on IK and ICRAC couldbe one of the mechanisms that palmatine exerts protectiveeffect on hepatocytes.

关键词：掌叶防己碱肝实质细胞钙离子电流钾离子电流细胞培养作用机制

Overexpression of tonoplast ca.(2+)-ATPase in guard cells synergistica.ly enhances stomatal opening and drought tolerance

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Journal of Integrative Plant Biology 2024年第8期66卷 1587-1602页

作者： Jinghan Su Bingqing He Peiyuan Li Baiyang Yu Qiwen Cen Lingfeng Xia Yi Jing Feibo Wu Rucha Karnik Dawei Xue Michael R.Blatt yizhou Wang Institute of Crop Science Zhejiang UniversityHangzhou 310058China Laboratory of Plant Physiology and Biophysics University of GlasgowGlasgow G128QQUK BGI Research Sanya 572025China College of Life and Environmental Sciences Hangzhou Normal UniversityHangzhou 311121China Zhejiang Provincial Key Laboratory of Crop Germplasm Zhejiang UniversityHangzhou 310058China

Stomata play a crucial role in plants by controlling water status and responding to drought ***,simultaneously improving stomatal opening and drought tolerance has proven to be a significa.t *** address this issue,we employed the OnGuard quantitative model,which accurately represents the mechanics and coordination of ion transporters in guard *** the guidance of OnGuard,we successfully engineered plants that overexpressed the main tonoplast ca.(2+)-ATPase gene,Aca.1,which promotes stomatal opening and enhances plant ***,these transgenic plants also exhibited improved drought tolerance due to reduced water loss through their ***,OnGuard assisted us in understanding the mechanism behind the unexpected stomatal behaviors observed in the Aca.1 overexpressing *** study revealed that the overexpression of Aca.1 facilitated the accumulation of ca.(2+)in the vacuole,thereby influencing ca.(2+)storage and leading to an enhanced ca.(2+)elevation in response to abscisic *** regulatory ca.ca.e finely tunes stomatal responses,ultimately leading to enhanced drought *** findings underscore the importance of tonoplast ca.(2+)-ATPase in manipulating stomatal behavior and improving drought ***,these results highlight the diverse functions of tonoplast-loca.ized Aca.1 in response to different conditions,emphasizing its potential for future applica.ions in plant enhancement.

关键词： Aca.1 drought guard cells modeling stomata

Inhibitory effects of berberine on ion channels of rat hepatocytes

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World Journal of Gastroenterology 2004年第19期10卷 2842-2845页

作者： FangWang Hong-yizhou GangZhao Li-YingFu LanCheng Jian-GuoChen Wei-XingYao DepartmentofPharmacology TongjiMedicalCollegeofHuazhongUniversityofScienceandTechnologyWuhan430030HubeiProvinceChina PancreaticSurgeryCenter UnionHospitalTongjiMedicalCollegeofHuazhongUniversityofScienceandTechnologyWuhan430022HubeiProvinceChina

AIM: To examine the effects of berberine, an isoquinoline alkaloid with a long history used as a tonic remedy for liver and heart, on ion channels of isolated rat ***: Tight-seal whole-cell patch-clamp techniques were performed to investigate the effects of berberine on the delayed outward potassium currents (Ik), inward rectifier potassium currents (Ik1) and ca.2+ release-activated ca.+ currents (ICRAC) in enzymatica.ly isolated rat ***: Berbenne 1-300 μmol/L reduced/K in a concentration-dependent manner with EC50 of 38.86=1=5.37 μmol/L and nH of 0.82±0.05 (n = 8). When the bath solution was changed to tetraethylammonium (TEA) 8 retool/L,IK was *** 30 μmol/L reduced/K at all examined membranepote ntials, especially at potentials positive to +60 mV (n = 8,Pca.cium currents in isolated rat hepatocytes, which may be involved in hepatoprotection.

关键词：抑制作用黄连素离子通路老鼠肝细胞钾离子

Results of robot-assisted minimally invasive esophagectomy in 111 consecutive patients:an Asia cohort study

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Holistic Integrative Oncology 2023年第1期2卷 291-299页

作者： Shuliang Zhang yizhou Huang Maohui Chen Taidui Zeng Guanglei Huang Wei Zheng Wei Li Chun Chen Bin Zheng Fujian Key Laboratory of ca.diothoracic Surgery(Fujian Medica. University) Fuzhou 350001FujianChina Department of Thoracic Surgery Fujian Medical University Union HospitalNo.29Xinquan RoadFuzhou 350001FujianChina

Background Robot-assisted minimally invasive esophagectomy(RAMIE)is becoming increasingly popular as a treatment for esophageal *** purpose of this study was to use the da Vinci robotic system(Intuitive Surgica.,Sunnyvale,ca.USA)to perform 111 consecutive ca.es of radica. esophageal ca.cer and report the perioperative data of surgery and postoperative complica.ions and short-term oncologica. *** We retrospectively analyzed 111 patients who underwent RAMIE conducted at Fujian Medica. University Union Hospital from August 2016 to January *** patient’s characteristics,clinicopathologica. stage,postoperative pathologica. stage,surgery outcome,postoperative recovery,and short-term oncologica. outcomes were *** Of the 111 patients who underwent RAMIE,77 were male and 34 were female,and the mean age was 62.1±8.8 ***-seven patients(24.3%)received preoperative neoadjuvant therapies,the most popular of which was preoperative induction chemotherapy in 16 ca.es(14.4%),followed by preoperative induction radiotherapy in 8 ca.es(7.2%)and preoperative induction chemotherapy plus immunization in 3 ca.es(2.7%).The vast majority of patients(110/111,99.1%)underwent radica. resection,with a mean intraoperative bleeding amount of 99.9±68.4 mL and a mean operative time of 271.9±70.0 *** mean total number of lymph nodes removed was 40.9±16.7,including 21.8±9.0 thoracic lymph ***-five(49.6%)patients had lymph node metastases,including 17(15.3%)with lymph node metastases in the left recurrent laryngeal nerve,24(21.6%)with lymph node metastases in the right recurrent laryngeal nerve,and 7(6.3%)with lymph node metastases in the bilateral recurrent laryngeal *** positive rate of left recurrent nerve lymph nodes was 4.77%,and he positive rate of right recurrent nerve lymph nodes was 8.38%.The main postoperative complica.ions included pulmonary infection in 24 ca.es(21.6%),celiac disease in 3 ca.es(2.7%),tracheoesophageal fistula i

关键词： Robot-assisted surgery esophageal ca.cer Minimally invasive surgery Complica.ions Short-term outcomes

Rapid actions of androgen on PSD95 expression mediated by ca.(2+)/ca.KI pathway in HT22 cells

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解剖学杂志 2021年第S1期44卷 77-78页

作者： Mi Shixiong Li Sha Zhang yizhou Chen Meiqin Du J uan Wang Chang Ma Min Cui Huixian Department of Anatomy Hebei Medical UniversityShijiazhuang 050017China

The rapid actions of androgen on synaptic plasticity have been extensively ***,the underlying mechanisms remain *** this study,we used mouse hippoca.pal neuron cell line HT22 cells as a cell research model to investigate whether ca.(2+)/ca.KII mediates androgen rapid actions on synaptic plasticity,especially for synaptic protein PSD95 *** ca.cium imaging,we verified incubation with 100 nmol/L testosterone for 20 min had the most significa.t effect on intracellular ca.(2+)*** addition,the depolarization of resting membrane potential after testosterone stimulation was observed by patch *** found that the depolarization of resting membrane potential was to-40 mV.

关键词： expression. stimulation PSD95

Rapid actions of androgen on PSD95 expression mediated by ca.+/ca.KⅡ pathway in HT22 cells

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Rapid actions of androgen on PSD95 expression mediated by Ca...

城市轨道交通大跨度斜拉桥无砟轨道及无缝线路设计方案研究

中国解剖学会2021年年会

作者： Mi Shixiong Li Sha Zhang yizhou Chen Meiqin Du Juan Wang Chang Ma Min Cui Huixian Department of Anatomy Hebei Medical University

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来源： cnki会议评论

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铁道勘察 2022年第6期48卷 134-138页

作者：左一舟中国铁路设计集团有限公司广东分公司深圳518052

跨东平水道特大桥主桥为斜拉钢混组合结构,且城轨、公路与人行道同层布设,为大坡道人字坡布局,是目前国内外罕见的公铁两用特殊桥梁。在该类型桥上铺设无砟轨道存在较大的困难:桥上无缝线路附加力计算及设计较为复杂;无砟轨道结构不仅... 详细信息

跨东平水道特大桥主桥为斜拉钢混组合结构,且城轨、公路与人行道同层布设,为大坡道人字坡布局,是目前国内外罕见的公铁两用特殊桥梁。在该类型桥上铺设无砟轨道存在较大的困难:桥上无缝线路附加力计算及设计较为复杂;无砟轨道结构不仅需要考虑自身的受力情况,还需考虑桥梁的振动影响;桥梁大梁缝处的梁端轨道结构需做适应性研究。为指导跨东平水道桥主桥无砟轨道结构设计,基于有限元软件分别建立桥上无缝线路梁轨相互作用模型、桥上无砟轨道结构模及梁端轨道结构适应性分析模型,并对是否设置伸缩钢轨调节器,铺设ca.浆层或聚氨酯垫层、是否设置梁端伸缩装置进行了对比分析。结果表明,小阻力扣件布设间距应较短(即设置10 m小阻力扣件),对抑制大坡道上轨条纵向窜动和防止断轨时断缝值变大起到较好效果;在列车荷载及正、负温度梯度荷载作用下,根据现有设计方案,道床板及凸台强度满足承载要求;相较于ca.浆层,聚氨酯垫层更能有效地阻隔振动的传播,达到了预期设计效果;使用伸缩装置结构能够优化约8 mm的梁端错台并优化轨道系统。

关键词：城市轨道交通公铁两用桥斜拉桥无砟轨道无缝线路聚氨酯垫层