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惠民凹陷煤岩生烃动力学及勘探有利区预测

成都理工大学学报（自然科学版） 2019年第1期46卷 64-69页

作者：郑欢张银联江峰杨芸朱遂珲长江大学地球科学学院武汉430100 中国石油塔里木油田公司新疆库尔勒841000 东北石油大学地球科学学院黑龙江大庆163318 中国石油青海油田测试公司甘肃敦煌736202 中国石油西南油气田分公司川西北气矿四川绵阳621700

在分析烃源岩平面发育、丰度、类型及成熟度基础上,采用高压釜模拟实验与动力学模型融合的方法,结合构造演化史研究,定量模拟惠民凹陷石炭-二叠系煤岩生气过程,预测有利勘探区。惠民地区石炭-二叠系煤岩地层中有机质以Ⅲ型为主,属于高... 详细信息

在分析烃源岩平面发育、丰度、类型及成熟度基础上,采用高压釜模拟实验与动力学模型融合的方法,结合构造演化史研究,定量模拟惠民凹陷石炭-二叠系煤岩生气过程,预测有利勘探区。惠民地区石炭-二叠系煤岩地层中有机质以Ⅲ型为主,属于高丰度、生气为主的烃源岩,并进入成熟-高成熟阶段,具有良好的生气基础;该煤岩具有2次生气特征:分别发生于260～200 Ma B.P.和80～55 Ma B.P.,累计生气率达75%,并与包裹体测温结果显示的成藏期一致。济阳地堑带东侧的白桥断层附近、曲堤潜山构造带的东北部构造高点和局部高点部位、西南缓坡带靠近气源区的小型气藏及王判镇潜山带的规模小、丰度高的"甜点"型气藏应该是勘探的重点目标。

关键词：煤岩生烃动力学有利区预测

王不留行籽耳穴贴压联合低频脉冲对产后缺乳产妇泌乳情况的影响

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临床医学研究与实践 2021年第20期6卷 173-175页

作者：谢亚丽张引莲孔雅君王转利凤翔县医院陕西宝鸡721400

目的探讨王不留行籽耳穴贴压联合低频脉冲对产后缺乳产妇泌乳情况的影响。方法选取2018年5月至2019年5月接收的210例产后缺乳产妇作为研究对象,以随机数字法将其分为对照组和观察组,各105例。对照组予以常规护理干预,观察组则在此基础... 详细信息

目的探讨王不留行籽耳穴贴压联合低频脉冲对产后缺乳产妇泌乳情况的影响。方法选取2018年5月至2019年5月接收的210例产后缺乳产妇作为研究对象,以随机数字法将其分为对照组和观察组,各105例。对照组予以常规护理干预,观察组则在此基础上加以王不留行籽耳穴贴压联合低频脉冲干预。比较两组的护理效果。结果观察组产后泌乳量分级为Ⅰ级的产妇占比明显高于对照组,Ⅲ级占比明显低于对照组(P48 h的产妇占比明显低于对照组(P<0.05)。观察组产后母乳喂养率为88.57%,显著高于对照组的63.81%(P<0.05)。观察组的满意度为95.24%,显著高于对照组的74.29%(P<0.05)。结论王不留行籽耳穴贴压联合低频脉冲用于产后缺乳产妇中,能够有效促进乳汁分泌,提高母乳喂养率,值得推广。

关键词：王不留行籽耳穴贴压低频脉冲产后缺乳

基于快速康复外科理念的护理策略对计划性剖宫产产妇产后恢复情况的影响

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临床医学研究与实践 2021年第16期6卷 184-186页

作者：张引莲谢亚丽刘娅娜李荣华凤翔县医院陕西宝鸡721400

目的观察基于快速康复外科理念的护理策略对计划性剖宫产产妇产后恢复情况的影响。方法将我院收治的352例计划性剖宫产产妇随机分为对照组(常规护理)和观察组(基于快速康复外科理念的护理策略),各176例。比较两组恢复情况、泌乳状况、... 详细信息

目的观察基于快速康复外科理念的护理策略对计划性剖宫产产妇产后恢复情况的影响。方法将我院收治的352例计划性剖宫产产妇随机分为对照组(常规护理)和观察组(基于快速康复外科理念的护理策略),各176例。比较两组恢复情况、泌乳状况、喂养情况、子宫复旧情况、自护能力及并发症发生情况。结果观察组拔管时间、术后首次排气时间、下床活动时间、疼痛持续时间、住院时间均短于对照组,初乳时间早于对照组,24 h内哺乳次数、术后第2天泌乳量均多于对照组,纯母乳喂养率、子宫复旧良好率高于对照组,产后24、48 h宫底高度均小于对照组,产后并发症总发生率低于对照组(P<0.05)。护理后,两组病情了解度、健康知识水平、自护责任感、自护技能评分均升高,且观察组高于对照组(P<0.05)。结论基于快速康复外科理念的护理策略在计划性剖宫产产妇中的护理效果理想,可促进产妇恢复,提高泌乳功能,促进子宫复旧,提高自护能力,减少产后并发症。

关键词：快速康复外科理念计划性剖宫产子宫复旧

A型肉毒毒素在带状疱疹后遗神经痛中的疗效及作用机制

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皮肤科学通报 2024年第4期41卷 372-378页

作者：张银连张景瑜柴宝肖礼祖郑跃陈宏翔深圳市前海蛇口自贸区医院广东深圳518055 深圳市南山区人民医院深圳大学医学院附属第六医院皮肤科广东深圳518052 深圳市南山区人民医院深圳大学医学院附属第六医院疼痛科广东深圳518052 南方医科大学南方医院皮肤科广东广州510515 华中科技大学同济医学院附属协和医院皮肤科湖北武汉430022

带状疱疹后遗神经痛(postherpetic neuralgia,PHN)是带状疱疹最常见的并发症,以疱疹部位皮肤烧灼或电击样疼痛为表现,常引起睡眠障碍、焦虑、抑郁等不良结果,严重影响患者的生活质量、身体机能和心理健康,给个人和社会带来相应的医疗和... 详细信息

带状疱疹后遗神经痛(postherpetic neuralgia,PHN)是带状疱疹最常见的并发症,以疱疹部位皮肤烧灼或电击样疼痛为表现,常引起睡眠障碍、焦虑、抑郁等不良结果,严重影响患者的生活质量、身体机能和心理健康,给个人和社会带来相应的医疗和经济负担。随着社会发展,人口老龄化,PHN发病率将逐年增高。肉毒毒素是一种神经毒性蛋白,研究表明,A型肉毒毒素(botulinum toxin-A,BTX-A)能够显著缓解PHN改善患者生活质量,但其作用机制尚未阐明。本文就BTX-A治疗PHN的有效性、安全性及作用机制的研究现状作一阐述,希望为临床医生治疗PHN提供帮助和指导。

关键词： A型肉毒毒素带状疱疹后遗神经痛镇痛作用机制

基于快速康复外科理念的护理干预在妇科腹腔镜手术患者围术期的应用效果

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临床医学研究与实践 2020年第30期5卷 179-181页

作者：谢亚丽张引莲孔雅君王雪丽凤翔县医院陕西宝鸡721400

目的探讨基于快速康复外科理念的护理干预在妇科腹腔镜手术患者围术期的应用效果。方法将2019年1月至2019年10月我院94例妇科腹腔镜手术患者按照随机数表法分为对照组和观察组,每组47例。对照组实施常规护理,观察组实施基于快速康复外... 详细信息

目的探讨基于快速康复外科理念的护理干预在妇科腹腔镜手术患者围术期的应用效果。方法将2019年1月至2019年10月我院94例妇科腹腔镜手术患者按照随机数表法分为对照组和观察组,每组47例。对照组实施常规护理,观察组实施基于快速康复外科理念的护理干预。比较两组的护理效果。结果护理后,除精神病性外,两组患者SCL-90量表其余9项评分均较护理前显著降低,且观察组低于对照组(P<0.05)。护理后,两组患者的ALB及Hb水平均降低,但观察组高于对照组(P<0.05)。观察组术后24 h VAS评分及并发症总发生率低于对照组(P<0.05)。观察组的护理满意度明显高于对照组(P<0.05)。结论基于快速康复外科理念的护理干预可有效改善妇科腹腔镜手术患者的心理状态,改善其营养状况,减少术后疼痛及并发症发生情况,提高护理满意度。

关键词：快速康复外科理念妇科腹腔镜手术围术期

Novel flavin-containing monooxygenase protein FMO1 interacts with CAT2 to negatively regulate drought tolerance through ROS homeostasis and ABA signaling pathway in tomato

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Horticulture Research 2023年第4期10卷 225-237页

作者： Lulu Wang yinlian Zhou Yin Ding Chunrui Chen Xueting Chen Nini Su Xingguo zhang Yu Pan Jinhua Li State Cultivation Base of Crop Stress Biology for Southern Mountainous land of Southwest University Academy of Agricultural SciencesSouthwest UniversityBeibeiChongqing 400715China Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River(Ministry of Education) College of Horticulture and Landscape ArchitectureSouthwest UniversityChongqing 400715China

Drought stress is themajor abiotic factor that can seriously affect plant growth and crop *** functions of flavin-containing monooxygenases(FMOs)are known in *** addmolecular oxygen to lipophilic compounds or produce reactive oxygen species(ROS).However,little information on FMOs in plants is ***,we characterized a tomato drought-responsive gene that showed homology to FMO,and it was designated as ***1 was downregulated promptly by drought and ABA *** functional analysis indicated that RNAi suppression of the expression of FMO1(FMO1-Ri)improved drought tolerance relative to wild-type(WT)plants,whereas overexpression of FMO1(FMO1-OE)reduced drought *** FMO1-Ri plants exhibited lower ABA accumulation,higher levels of antioxidant enzyme activities,and less ROS generation comparedwith theWTand FMO1-OE plants under drought ***-seq transcriptional analysis revealed the differential expression levels of many drought-responsive genes thatwere co-expressed with FMO1,including PP2Cs,PYLs,WRKY,and *** Y2H screening,we found that FMO1 physically interacted with catalase 2(CAT2),which is an antioxidant enzyme and confers drought *** findings suggest that tomato FMO1 negatively regulates tomato drought tolerance in the ABA-dependent pathway and modulates ROS homeostasis by directly binding to SlCAT2.

关键词： mono drought Transgenic

Procalcitonin and Liver Disease: A Literature Review

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Journal of Clinical and Translational Hepatology 2019年第1期7卷 51-55页

作者： Ruolin Dong Bo Wan Su Lin Mingfang Wang Jiaofeng Huang yinlian WU Yilong WU Nanwen zhang Yueyong Zhu The First Affiliated Hospital of Fujian Medical University FuzhouChina Liver Research Center The First Affiliated Hospital of Fujian Medical UniversityFuzhouChina Department of Pharmacology School of PharmacyFujian Medical UniversityFuzhouChina

Procalcitonin(PCT)is a widely used biomarker for the diagnosis of bacterial *** is produced by various organs and the liver is considered to be the most important site of *** liver dysfunction has been shown to influence PCT *** with no sources of infection who have liver disease are observed to have increased serum levels of PCT,thereby reducing the diagnostic utility and value within this particular patient ***,we have summarized the relationship between PCT and liver disease,including liver cirrhosis,liver failure,and liver transplantation.

关键词： Procalcitonin Liver disease Infection

The Association between Meteorological Factors and the Prevalence of Acute-on-chronic Liver Failure:A Population-based Study,2007-2016

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Journal of Clinical and Translational Hepatology 2019年第4期7卷 341-345页

作者： Su Lin Lifen Han Dongliang Li Ting Wang Zimu Wu Haoyang zhang Zhansong Xiao yinlian Wu Jiaofeng Huang Mingfang Wang Yueyong Zhu Liver Research Center of the First Affiliated Hospital of Fujian Medical University FuzhouFujianChina Department of Infectious Disease Mengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhouFujianChina Department of Hepatobiliary Disease 900 Hospital of PLAFuzhouFujianChina School of Public Health Sun Yat-sen UniversityGuangzhouGuangdongChina Fujian Medical University FuzhouFujianChina

Background and Aims:The aim of this study was to inves-tigate the effect(s)of meteorological factors on the preva-lence of acute-on-chronic liver failure(ACLF)based on 10-years'worth of population ***:We retrospec-tively collected ACLF case data from January 2007 to Decem-ber 2016 from three major hospitals in Fuzhou City,*** data,including rainfall,mean temperature,differen-ces in temperature(delta temperature)and mean humidity for each month were downloaded from the China Climatic Data Service *** data collection,Poisson regression analysis was used to estimate the effect(s)of climatic factors on the risk of the prevalence of ***:The population consisted of a total of 3510 cases,with a mean age of 44.7±14.8 years-old and with 79.8%being *** analyzing the population data,we found a growing trend and seasonal pattern of monthly counts of ACLF-related hospitalization throughout the past ***,the primary peak of ACLF prevalence was in January and the secondary peak was in *** regression showed mean temperature(risk ratio=0.991,95%CI=0.986–0.996)and mean humidity(risk ra-tio=1.011,95%CI=1.006–1.017)to be independently cor-related with the monthly cases of *** results suggest that every unit increase of mean temperature(1°C)and mean humidity(1%)are associated with 0.991-and 1.011-fold changes of ACLF cases,*** and delta temper-ature did not appear to affect the prevalence of this ***:The hospitalization for ACLF peaks in January and *** temperature and high humidity appear to func-tion as factors contributing to this seasonal pattern.

关键词： Acute-on-chronic liver failure Seasonal variation Temperature Humidity

Effects of dietary leucine supplementation on the gene expression of mammalian target of rapamycin signaling pathway and intestinal development of broilers

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Animal Nutrition 2015年第4期1卷 313-319页

作者： yinlian Chang Huiyi Cai Guohua Liu Wenhuan Chang Aijuan Zheng Shu zhang Ruibo Liao Wei Liu Yang Li Jia Tian The Key Laboratory of Feed Biotechnology of the Ministry of Agriculture Feed Research Institute Chinese Academy of Agricultural Sciences

This experiment was to investigate the effects of dietary leucine supplementation on the gene expression of mammalian target of rapamycin(mTOR) signaling pathway and intestinal development of broilers. A total of 384 one-day-old broilers were randomly assigned into 4 treatments with 6 replicates(16 broilers per replicate). Broilers in these treatment groups were offered the following diets with 1.37,1.77,2.17 and2.57% of leucine. These diet treatments were named 1.37 TM, 1.77 TM, 2.17 TM, and 2.57 TM. The experiment lasted 21 days and all birds had free access to feed and water. Results indicated that there was no significant difference in body weight, average daily gain and average feed intake among all treatments(P > 0.05). The broiler duodenal villus height in 2.57 TM was the lowest, but the highest occurred in1.37 TM on d 7 and 14(P < 0.05). The villus height in the jejunum and ileum increased along with leucine level from 1.37 to 2.17%. The villus height of jejunum was significantly higher in 2.17 TM than in 1.37 TM on d 7 and 14, and the ratio of villus height to crypt depth(V:C) in the duodenum, jejunum and ileum increased significantly(P < 0.05) on d 21. The gene expression level of mTOR in the duodenum decreased with increasing leucine level and was higher in 1.37 TM than in 2.57 TM on d 7 and 14(P < 0.05). On d 14 and 21 of the trial, the expression of S6 K1 in the duodenum was higher in 1.37 TM than in 2.57 TM(P < 0.05), and the expression of mTOR, S6 K1 in the jejunum and ileum increased with increasing leucine level form 1.37 to 2.17%, whereas a significant difference occurred between 1.37 TM and 2.17 TM(P< 0.05).In conclusion, the addition of leucine fails to enhance the growth performance of broilers. However,leucine can improve intestinal development by enhancing villus height and V:C ratio in the jejunum and ileum. Moreover, the expression of mTOR, S6 K1 increased as the level of dietary leucine was elevated from 1.37 to 2.17%.

关键词： Leucine Broiler mTOR pathway Intestinal development