The Association between Meteorological Factors and the Prevalence of Acute-on-chronic Liver Failure:A Population-based Study,2007-2016

作     者：Su Lin Lifen Han Dongliang Li Ting Wang Zimu Wu Haoyang Zhang Zhansong Xiao Yinlian Wu Jiaofeng Huang Mingfang Wang Yueyong Zhu 

作者机构：Liver Research Center of the First Affiliated Hospital of Fujian Medical UniversityFuzhouFujianChina Department of Infectious DiseaseMengchao Hepatobiliary Hospital of Fujian Medical UniversityFuzhouFujianChina Department of Hepatobiliary Disease900 Hospital of PLAFuzhouFujianChina School of Public HealthSun Yat-sen UniversityGuangzhouGuangdongChina Fujian Medical UniversityFuzhouFujianChina 

出 版 物：《Journal of Clinical and Translational Hepatology》 (临床与转化肝病杂志（英文版）)

年 卷 期：2019年第7卷第4期

页      面：341-345页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：This study was funded by Fujian Provincial Health Technology Project(2016-CX-33) Fujian Science and Technology Project(2017J01187) Fujian Province Science and Technology Program(2019D002) Fuzhou Science and Technology Program (2018-S-103-1).They supported the analysis of the data and writing of the manuscript 

主　　题：Acute-on-chronic liver failure Seasonal variation Temperature Humidity 

摘      要：Background and Aims:The aim of this study was to inves-tigate the effect(s)of meteorological factors on the preva-lence of acute-on-chronic liver failure(ACLF)based on 10-years worth of population ***:We retrospec-tively collected ACLF case data from January 2007 to Decem-ber 2016 from three major hospitals in Fuzhou City,*** data,including rainfall,mean temperature,differen-ces in temperature(delta temperature)and mean humidity for each month were downloaded from the China Climatic Data Service *** data collection,Poisson regression analysis was used to estimate the effect(s)of climatic factors on the risk of the prevalence of ***:The population consisted of a total of 3510 cases,with a mean age of 44.7±14.8 years-old and with 79.8%being *** analyzing the population data,we found a growing trend and seasonal pattern of monthly counts of ACLF-related hospitalization throughout the past ***,the primary peak of ACLF prevalence was in January and the secondary peak was in *** regression showed mean temperature(risk ratio=0.991,95%CI=0.986–0.996)and mean humidity(risk ra-tio=1.011,95%CI=1.006–1.017)to be independently cor-related with the monthly cases of *** results suggest that every unit increase of mean temperature(1°C)and mean humidity(1%)are associated with 0.991-and 1.011-fold changes of ACLF cases,*** and delta temper-ature did not appear to affect the prevalence of this ***:The hospitalization for ACLF peaks in January and *** temperature and high humidity appear to func-tion as factors contributing to this seasonal pattern.