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一种基于最小汉明距离的卷积码译码算法研究

装备指挥技术学院学报 2002年第4期13卷 59-63页

作者：刘颖喻文芳周辉装备指挥技术学院电子工程系北京101416

在讨论费诺算法的基础上，提出了一种基于汉明距离的译码算法，该算法省去了门限增量T0，而实质上，基于汉明距离的译码算法和费诺算法是一致的。最后运用EDA（电子设计自动化）开发软件进行模拟，结果表明该算法在性能上比费诺算法优... 详细信息

在讨论费诺算法的基础上，提出了一种基于汉明距离的译码算法，该算法省去了门限增量T0，而实质上，基于汉明距离的译码算法和费诺算法是一致的。最后运用EDA（电子设计自动化）开发软件进行模拟，结果表明该算法在性能上比费诺算法优越得多。

关键词：汉明距离码树图费诺算法卷积码译码算法概率译码

Metastable seed-crystals: epitaxial growth of branched-array organic heterostructure nanowires

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Science China Chemistry 2025年

作者： Jin Feng Zhen-Yu Geng Ting-Yao Song ying-Xin Ma Chuan-Zeng Wang Wei Zhang Hong-Tao Lin Jin zhou Shu-Ping Zhuo Shu-Hai Chen Xue-Dong Wang School of Chemistry and Chemical Engineering Shandong University of Technology Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials & DevicesSoochow University College of Chemistry and Chemical Engineering Hunan Normal University

Tunable light–matter interactions are exhibited by organic low-dimensional crystals, making these crystals a promising platform for organic photonics. However, the precise synthesis of organic low-dimensional crystals remains challenging due to the stochastic nature of molecular nucleation processes. Herein, the directed nucleation process is driven by the introduction of metastable seed-crystals as the trunk, which ultimately leads to branched-array organic heterostructures. The successful formation of organic heterostructures with high-density branched arrays is attributed to the highest attachment energy (Eatt（023）=-104.25 kcal mol-1) of the exposed （023） crystal plane during the seed-crystal growth route. Significantly, these as-prepared heterostructures inherently have an ultralow lattice mismatch ratio η of 0.7%between trunk and branch, which contributes to the multi-channel photon transportation. Therefore, this work provides valuable insights into a versatile synthetic strategy for accessing low-dimensional heterostructures for integrated optoelectronics.

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Protein-based functional hydrogel improves cutaneous nerve repair and diabetic wound healing

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Nano Research 2025年第1期18卷 586-596页

作者： Hanzhi Lu Mingrui Cui Yi Wang Xinran Du Xinyi zhou Yuhan fang Xiaoyan Gao ying Peng Jianyong Zhu Guang Yang Fulun Li Department of Dermatology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine College of Biological Science and Medical EngineeringDonghua UniversityShanghai 201620China Clinical Laboratory Medicine Center Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China

Cutaneous nerve regeneration in diabetic wounds remains a challenge for current clinical ***,a natural protein-based functional hydrogel is developed using keratin as the sole matrix,and protocatechuic aldehyde(PA)and zinc ions as the building blocks through dual-dynamic crosslinking reactions of thiol-aldehyde addition and catecholzinc ions *** unique structural design endows the hydrogel with excellent injectability,skin adhesion,self-healing and antibacterial ability,and *** addition,this hydrogel acts as a drug carrier for the loading and sustained release of phellopterin(PP),a natural compound extracted from traditional Chinese medicine Angelica *** findings demonstrate that the PP-loaded hydrogel promotes cutaneous nerve regeneration,angiogenesis and tissue remodeling in the full-thickness wounds in both db/db and streptozotocin-induced C57BL/6 diabetic mice,notably by the synergistic effect of zinc ions and PP,showing a great potential in diabetic wound therapy.

关键词： functional hydrogel cutaneous nerve regeneration dynamic crosslinking diabetic wounds

NOX1 siRNA对TNF-α诱导的A549细胞凋亡的影响

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郑州大学学报（医学版） 2016年第5期51卷 591-594页

作者：夏艳秋王娜阙菡雅徐小艳薛腾燕贞姚武刘莹周舫郑州大学公共卫生学院劳动卫生学教研室郑州450001 郑州市疾病预防控制中心公共卫生科郑州450000 郑州大学第一附属医院呼吸内科郑州450052

目的:探讨NOX1对TNF-α诱导的A549细胞凋亡的影响。方法:将A549细胞分为3组,空白组、TNF-α组和TNF-α+NOX1 siRNA组。TNF-α+NOX1 siRNA组细胞采用瞬时转染技术转染特异性NOX1 siRNA,转染12 h后用含TNF-α(10μg/L)的培养基继续培养;... 详细信息

目的:探讨NOX1对TNF-α诱导的A549细胞凋亡的影响。方法:将A549细胞分为3组,空白组、TNF-α组和TNF-α+NOX1 siRNA组。TNF-α+NOX1 siRNA组细胞采用瞬时转染技术转染特异性NOX1 siRNA,转染12 h后用含TNF-α(10μg/L)的培养基继续培养;空白组和TNF-α组细胞分别用培养基和含TNF-α的培养基培养。48h后,采用Annexin V-FITC和PI双染法检测细胞凋亡率,DCFH荧光标记法检测细胞中ROS的表达量,Western blot法检测NOX1及p-JNK蛋白的表达水平。结果:与空白组相比,TNF-α组细胞凋亡率和ROS表达量升高(P<0.05),NOX1和p-JNK蛋白表达水平升高(P<0.05);与TNF-α组比较,TNF-α+NOX1 siRNA组细胞凋亡率和ROS表达量降低(P<0.05),细胞中NOX1和p-JNK蛋白表达水平也降低(P<0.05)。结论:NOX1可能通过增加ROS的表达,进而激活JNK/MAPK信号通路,引起A549细胞的凋亡。

关键词： A549细胞 NOXl TNF-α 凋亡

Chinese Expert Consensus on Clinical Application of Female Contraceptive Methods

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Reproductive and Developmental Medicine 2018年第4期2卷 208-223页

作者： Li-Nan Cheng Wen Di Yan Ding Guang-Sheng Fan Xiang-ying Gu Min Hao Jing He Li-Na Hu Ke-Qin Hua Wei Huang Li Jin Bei-Hua Kong Jing-He Lang Jin-Hua Leng Jian Li Cai-Xia Liu Guan-Yuan Liu Lei Song Xiao-Ye Wang Shang-Chun Wu Min Xue Hui-Xia Yang Qing Yang Shu-Zhong Yao Zhen-Yu Zhang ying-fang zhou Lan Zhu Shanghai Institute of Planned Parenthood Research ShanghaiChina Department of Obstetrics and Gynecology Renji HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Gynecology The First Affiliated Hospital of Xinjiang Medical UniversityÜrümqiChina Department of Obstetrics and Gynecology Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijingChina Department of Family Planning Tianjin Medical University General HospitalTianjinChina Department of Obstetrics and Gynecology The Second Hospital of Shanxi Medical UniversityTaiyuanChina Department of Obstetrics Zhejiang University School of MedicineHangzhouChina Department of Obstetrics and Gynecology The Second Affiliated Hospital of Chongqing Medical UniversityChongqingChina Department of Gynecology Obstetrics and Gynecology Hospital of Fudan UniversityShanghaiChina Department of Obstetrics and Gynecology The West China Second University HospitalSichuan UniversityChengduChina Department of Obstetrics and Gynecology Qilu Hospital of Shandong UniversityJinanChina Department of Family Planning Beijing Obstetrics and Gynecology HospitalCapital Medical UniversityBeijingChina Department of Obstetrics and Gynecology Shengjing Hospital of China Medical UniversityShenyangChina Department of Obstetrics and Gynecology Beijing Chao-Yang HospitalCapital Medical UniversityBeijingChina Department of Obstetrics and Gynecology PLA General HospitalBeijingChina Department of Obstetrics and Gynecology Peking University Third HospitalBeijingChina Research Institute of National Health Commission of the People's Republic of China BeijingChina Department of Gynecology The Third Xiangya Hospital of Central South UniversityChangshaChina Department of Obstetrics and Gynecology Peking University First HospitalBeijingChina Department of Obstetrics and Gynecology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina

Unintended pregnancy is a global issue, with approximately 85,000,000 women around the world having unintended pregnancy annually. The contents of clinical application of women’s contraceptive methods are very wide, involving multiple areas. This consensus deeply discusses the specific contraceptive needs at different statuses, combined with gynecological diseases, postabortion contraception, and postpartum family planning, ensuring the correct use of contraceptive methods under the corresponding status. The top priority of the consensus is the specific contraception consensus section for women combined with gynecological diseases because medical treatment effect as well as side effects should be weighed carefully. The consensus is to make high-efficiency and individual contraceptive strategy for different groups based on multidisciplinary(gynecology, obstetrics, and family planning) and multidimensional aspects, which can provide uniform guidance for medical and health organizations under the condition as relevant global guidance or consensus is still lacking.

关键词： Contraceptive Methods Gynecological Disease Postabortion Contraception Postpartum Family Planning Unintended Pregnancy

Uterine tumor resembling an ovarian sex cord tumor:A case report and review of literature

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World Journal of Clinical Cases 2021年第23期9卷 6907-6915页

作者： fang-fang zhou ying-Tao He ying Li Min Zhang fang-Hong Chen Department of Ultrasound Lishui Central HospitalThe Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina Department of Pathology Lishui Central HospitalThe Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina

BACKGROUND Endometrial stromal tumors originate from the endometrial stroma and account for<2%of all uterine *** tumor resembling an ovarian sex cord tumor(UTROSCT)is a rare histological class of endometrial stromal and related tumors according to the latest World Health Organization classification of female genital ***,we report a case of UTROSCT in a 51-year-old *** SUMMARY A 51-year-old woman had irregular menses for 6 *** patient visited a local hospital for vaginal *** computed tomography(CT)showed a mass in the pelvic *** days later,she came to our hospital for further *** results of contrast-enhanced CT and pelvic ultrasound at our hospital suggested a malignant pelvic *** then underwent total removal of the uterus with bilateral *** histological examination showed that the tumor cells had abundant cytoplasm,ovoid and spindle-shaped nuclei,fine chromatin,a high nucleoplasm ratio,and a lamellar *** findings were consistent with UTROSCT,and the results of immunohistochemical analysis supported that *** tumor was International Federation of Gynecology and Obstetrics stage *** adjuvant therapy was administered after radical *** patient was followed up for 58 mo,and no recurrence was *** We report a case of UTROSCT with abnormal menstruation as a symptom,which is one of the most common *** patients with vaginal bleeding,ultrasonography can be used as a screening test because of its convenience,speed,and lack of radiation *** patients with long-term tamoxifen use,routine monitoring of the endometrium is *** UTROSCT may have low malignant potential,surgery remains the primary management ***,fertility preservation in patients of childbearing age is a vital consideration.

关键词： Uterine tumor resembling an ovarian sex cord tumor Endometrial stromal tumor Pelvic Irregular menses Surgery Case report

谱系1和8重组猪繁殖与呼吸综合征病毒的分离鉴定与遗传进化分析

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动物医学进展 2025年第1期46卷 29-37页

作者：邹舟黎颖韦莹莹刘惠僮韦祖樟广西大学动物科学技术学院动物传染病与分子免疫学实验室广西南宁530005 广西壮族自治区兽用生物制品工程研究中心广西南宁530005 广西畜禽繁育与疾病防控重点实验室广西南宁530004

2023年从广西疑似发生猪繁殖与呼吸综合征病毒(PRRSV)感染猪场的病猪肺脏组织中分离到1株PRRSV,将其命名为GXWZ20230831。采用RT-PCR扩增其全基因组序列并测序,分析遗传进化特点。结果显示,GXWZ20230831能够在Marc-145细胞上增殖,且产... 详细信息

2023年从广西疑似发生猪繁殖与呼吸综合征病毒(PRRSV)感染猪场的病猪肺脏组织中分离到1株PRRSV,将其命名为GXWZ20230831。采用RT-PCR扩增其全基因组序列并测序,分析遗传进化特点。结果显示,GXWZ20230831能够在Marc-145细胞上增殖,且产生明显的细胞病变;该毒株全基因组长度为15019个核苷酸(nt),与基因2型PRRSV谱系1 NADC30-like毒株的同源性最高,为94.0%,与基因1型PRRSV代表毒株Lelystad virus同源性最低,仅为60.0%;通过Nsp2氨基酸序列比对,结果发现GXWZ20230831存在NADC30-like典型的131(111+1+19)个氨基酸的不连续缺失模式;与美洲型代表株VR2332相比,GXWZ20230831的GP5蛋白在非中和抗原表位发生了V27A、V185A以及R191K 3处突变,同时在GP5蛋白中存在4个潜在的N-糖基化位点;构建的全基因组序列、nsp2基因、ORF5基因遗传进化树均显示该毒株处于谱系1的分支;重组分析表明,GXWZ20230831是1株以谱系1经典毒株NADC30为骨架,谱系8毒株提供重组片段的重组毒株,重组断点位于基因组的nsp1(458-1821 nt)和Nsp4(5405-8179 nt)中。研究结果可为掌握广西地区的PRRSV遗传变异规律提供参考,为制定防控措施提供科学依据。

关键词：猪繁殖与呼吸综合征病毒分离鉴定重组遗传进化分析

Histone 3 lysine 36 to methionine mutations stably interact with and sequester SDG8 in Arabidopsis thaliana

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Science China(Life Sciences) 2018年第2期61卷 225-234页

作者： Guang Lin ying zhou Min Li Yuda fang National key Laboratory of Plant Molecular Genetics Chinese Academy of Sciences Center for Excellence in Molecular Plant SciencesInstitute of Plant Physiology and Ecology Chinese Academy of Sciences University of Chinese Academy of Sciences Shanghai 200032 China

Post-transcriptional modifications of histones play important roles in various biological processes. Here, we report that Arabidopsis plants overexpressing histone H3 lysine to methionine mutations at histone H3.1K36(H3.1K36M) and H3.3K36(H3.3K36M) have serious developmental defects with early-flowering and change in the modifications of endogenous histone H3, including acetylation at lysine 9(H3K9ac), trimethylation at lysine 27(H3K27me3), di-and tri-methylation at lysine 36(H3K36me2 and H3K36me3). In addition, H3K36M mutation alters its subcellular localization and interacts with H3K36 methyltransferase SDG8. Our results support a model in which H3K36M stably interacts with SDG8, and inhibits the activity of SDG8 by sequestering SDG8, resulting in a dominant negative effect to affect the proper expression levels of a variety of genes and plant development.

关键词： histone H3 lysine to methionine mutation SDG8 dominant negative effect Arabidopsis

控制方向未知的受限多智能体系统的预设时间模糊控制

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工程科学学报 2025年第1期47卷 121-129页

作者：李菲周超范利蓉王芳燕山大学理学院秦皇岛066004 河北农业大学海洋学院秦皇岛066003

综合考虑受控制方向未知、输入受限和状态时延影响的有领导者多智能体系统的编队控制问题,设计基于模糊逻辑系统的预设时间一致性控制策略.为了保证编队输出误差在预设时间内满足预定的约束范围要求,引入预设时间性能函数,构造Lyapunov-... 详细信息

综合考虑受控制方向未知、输入受限和状态时延影响的有领导者多智能体系统的编队控制问题,设计基于模糊逻辑系统的预设时间一致性控制策略.为了保证编队输出误差在预设时间内满足预定的约束范围要求,引入预设时间性能函数,构造Lyapunov-Krasovskii(L-K)泛函解决状态时延问题,将外界干扰和L-K泛函的导数中的部分项定义为未知非线性函数,并利用模糊逻辑系统对其进行估计,利用Nussbaum函数和均值定理分别处理控制方向未知和输入受限问题,基于以上设计,提出预设时间模糊控制策略,并通过Lyapunov稳定性理论,分析闭环系统的有界稳定性,数值对比仿真和两级化学反应器应用仿真说明控制方法的有效性.

关键词：多智能体系统状态时延输出误差约束输入受限控制方向未知