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Magnetic properties of α-Fe_2O_3 nanopallets

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Rare Metals 2019年第1期38卷 14-19页

作者： ying-ying xu Long Wang Tong Wu Rong-Ming Wang Beijing Key Laboratory for Magneto-Photoelectrical Composite and Interface Science School of Mathematics and PhysicsUniversity of Science and Technology Beijing Department of Equipment Manufacture Zhongshan Torch Polytechnic Division of Energy and Environmental Measurement National Institute of Metrology

It is the result of a systemic study about uniform hematite nanopallets with length of about 100 nm, width of about 30 nm, and thickness of less than 10 nm. The sample has superparamagnetic(SPM) properties above the blocking temperature of ～16 K. The temperature dependence of magnetization was well fitted by Bloch T^(3/2) law considering the dipolar interaction of the particles. The field dependence of magnetization was fitted with revised Langevin *** magnetization of the weak ferromagnetic(WF) canted spins contributes to the linear portion in the high field region;the surface uncompensated spins and the parasitic ferromagnetic moments due to the canted spins both contribute to the particle moments and the superparamagnetic behavior.

关键词： α-Fe2O3 nanopallets Magnetic property Superparamagnetic behavior Canted spins

A Local Limit Theorem for Solutions of BSDEs with Mao's non-Lipschitz Generator

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Acta Mathematicae Applicatae Sinica 2008年第2期24卷 329-336页

作者： Yu-chun Liu Long Jiang ying-ying xu Department of Mathematics China University of Mining and Technology Xuzhou 221116 China School of Mathematics Fudan University Shanghai 200433 China

This paper establishes a local limit theorem for solutions of backward stochastic differential equations with Mao＇s non-Lipschitz generator, which is similar to the limit theorem obtained by [3] under the Lipschitz a... 详细信息

关键词： Backward stochastic differential equation Mao's non-Lipschitz generator local limit theorem

Carbon-based nanomaterials cause toxicity by oxidative stress to the liver and brain in Sprague-Dawley rats

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Nuclear Science and Techniques 2024年第6期35卷 54-64页

作者： ying-ying xu Chan Jin Meng Wu Jian-Ye Zhou Hui-Ling Wei Department of Gastroenterology China-Japan Friendship HospitalBeijing 100029China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China Institute of Particle and Nuclear Physics College of PhysicsHenan Normal UniversityXinxiang 453007China

Carbon-based nanomaterials have important research significance in various disciplines,such as composite materials,nanoelectronic devices,biosensors,biological imaging,and drug ***,the human and ecological risks associated with carbon-based nanomaterials have received increasing ***,the biological safety of carbon based nanomaterials has not been systematically *** this study,we used different types of carbon materials,namely,graphene oxide(GO),single-walled carbon nanotubes(SWCNTs),and multiwalled carbon nanotubes(MWCNTs),as models to observe their distribution and oxidative damage in *** results of Histopathological and ultrastructural examinations indicated that the liver and lungs were the main accumulation targets of these ***-μ-XRF analysis revealed that SWCNTs and MWCNTs might be present in the *** shows that the three types of carbon-based nanomaterials could cross the gas-blood barrier and eventually reach the liver *** addition,SWCNTs and MWCNTs could cross the blood-brain barrier and accumulate in the cerebral *** increase in ROS and MDA levels and the decrease in GSH,SOD,and CAT levels indicated that the three types of nanomaterials might cause oxidative stress in the *** suggests that direct instillation of these carbon-based nanomaterials into rats could induce ROS *** addition,iron(Fe)contaminants in these nanomaterials were a definite source of free ***,these nanomaterials did not cause obvious damage to the rat brain *** deposition of selenoprotein in the rat brain was found to be related to oxidative stress and Fe *** information may support the development of secure and reasonable applications of the studied carbon-based nanomaterials.

关键词： Carbon-based nanomaterials Oxidative stress Trace element distribution TEM SR-μ-XRF

Effect of Postoperativeω-3 Fatty Acid Immunonutritional Therapy on NK Cell Gene Methylation in Elderly Patients with Gastric Cancer

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Current Medical Science 2022年第2期42卷 373-378页

作者： Li-ning xu ying-ying xu Gui-ping LI Bo YANG Department of General Surgery The Second Medical Center&National Clinical Research Center for Geriatric DiseasesChinese PLA General HospitalBeijing100853China Department of Internal Medicine Henan Cancer HospitalZhengzhou450003China Department of Radiology Hubei Province Integrated Hospital of Chinese and Western MedicineWuhan430015China Department of Radiology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China

Objective This study aims to investigate the effect ofω-3 fatty acid immunonutritional therapy on natural killer(NK)cell gene methylation and function in elderly patients with gastric *** A total of 70 cases of elderly patients with gastric cancer were randomized into theω-3 fatty acid group and placebo group,according to the type of nutritional support *** methylation status of the tumor necrosis factor(TNF)-αgene promoter in peripheral NK cells was detected by methylation specific polymerase chain reaction,and the TNF-αlevel in peripheral NK cells was detected by enzyme-linked immunosorbent *** After 14 days of immunonutritional therapy withω-3 fatty acid or placebo,patients in theω-3 group had significantly higher average NK cell activity(0.27 vs.0.24,P=0.013)and lower percentages of TNF-αgene promoter methylation(25.7%vs.60%,P<0.05)than the placebo ***,there were no significant differences in the concentration of albumin,prealbumin and TNF-αin serum,and the NK cell count between theω-3 group and placebo *** The postoperative application ofω-3 fatty acid may improve the activity of NK cells,which is correlated to the methylation status of the TNF-αgene promoter.

关键词： perioperative gastric carcinoma natural killer cell DNA methylation immune nutrition

Establishment of an Assessment System for the Prediction of Severe Post-operative Complications after Hepatectomy Based on Preoperative Parameters

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Current Medical Science 2022年第5期42卷 1088-1093页

作者： Li-ning xu ying-ying xu Gui-ping LI Bo YANG Department of General Surgery The Second Medical Center and National Clinical Research Center for Geriatric DiseasesChinese PLA General HospitalBeijing100853China Department of Internal Medicine Henan Cancer HospitalZhengzhou450003China Department of Radiology Hubei Province Integrated Hospital of Chinese and Western MedicineWuhan430015China Department of Radiology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China

Objective At present,there is no appropriate system to evaluate the severe complications of liver surgery through the preoperative *** study aimed to design and verify a risk assessment system for the prediction of severe post-operative complications after a hepatectomy based on the preoperative *** A retrospective analysis was performed on 1732 patients who had undergone liver *** severity of the complications was graded by Accordion Severity Grading of post-operative *** variables were screened by multivariate analysis,and graded scores were assigned to the selected variables.A logistic regression equation was used to form the liver operation risk formula(LORF)for the prediction of severe post-operative *** LORF was verified by the receiver operating characteristic(ROC)*** The multivariate correlation analysis revealed the independent influencing factors of the severe post-operative complications of liver surgery were Child-Pugh grade(OR=4.127;P<0.001),medical diseases requiring drug treatment(OR=3.092;P<0.001),the number of liver segments to be removed(OR=2.209;P=0.006),organ invasion(OR=4.538;P=0.024),and pathological type(OR=4.023;P=0.002).The binomial logistic regression model was established to obtain the calculation formula(LORF)of the severe complication *** area under the ROC curve(AUC)of the LORF was *** cut-off value of the expected probability of severe complications was 0.3225(32.25%).Furthermore,in the validation data set,the corresponding AUC of the LORF was *** As a novel and simplified assessment system,the LORF could effectively predict the severe post-operative complications of liver surgery through the preoperative factors,and therefore it could be used to evaluate the risk of severe liver surgical complications before surgery.

关键词： liver surgery complication prediction

Effect of CICARE communication nursing model combined with motivational psychological intervention in patients with postintensive care unit syndrome

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World Journal of Psychiatry 2023年第9期13卷 707-713页

作者： Sun-Ju She ying-ying xu Department of Neurosurgery Dushu Lake Hospital Affiliated to Soochow UniversitySuzhou 215000Jiangsu ProvinceChina Emergency Intensive Care Unit Dushu Lake Hospital Affiliated to Soochow UniversitySuzhou 215000Jiangsu ProvinceChina

BACKGROUND Post-intensive care syndrome(PICS)is a term used to describe a constellation of new or worsened dysfunctions in the physical,cognitive,or mental health status of critically ill patients after their discharge from the intensive care unit(ICU).These dysfunctions persist beyond the acute phase of illness and have a significant impact on both the patient and their ***,Introduce,Communicate,Ask,Respond,Exit(CICARE)communication advocates that patients should be respected and accepted when receiving medical *** should attach importance to the communication mode of feelings,including connection,introduction,communication,ask,response,and exit 6 *** To assess the impact of CICARE communication on the reduction of anxiety,depression,and post-traumatic stress disorder(PTSD)symptoms in patients transitioning from the ICU to other care *** This prospective,randomized,controlled study was performed between October 2021 and March *** Care Unit Memory Tool was used to evaluate patients’ICU *** Hospital Anxiety and Depression Scale was employed to determine the presence of anxiety or depression *** of Event Scale-Revised was utilized to assess the presence of *** data were processed and analyzed using R language software version *** measurement data were expressed as mean±SD,and the t test was *** count data were analyzed by theχ2 test and expressed as[n(%)].RESULTS In total,248 subjects were included in this *** them,206 were successfully followed up for three months after transfer from the ICU,and 42 cases were lost to *** was no significant difference in the composition of ICU memory between the two *** application of the CICARE communication nursing model combined with the motivational psychological intervention nursing model,as well as the adoption of only the motivational psychological intervention nursing model,demonstrated favorable effects on PI

关键词： Connect,Introduce,Communicate,Ask,Respond,Exit Post-intensive care syndrome Motivational psychological intervention

Synthesis and cytotoxic activity of 3-phenyl-4-substituted-β-carbolines

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Chinese Chemical Letters 2012年第11期23卷 1230-1232页

作者： Liu Liu ying ying xu Ze Qi Yang Jian Nan Xiang Guang Yu xu Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research(Ministry of Education) College of Chemistry and Chemical EngineeringHunan Normal UniversityChangsha 410081China College of Chemistry and Chemical Engineering Hunan UniversityChangsha 410082China

A new class of 3-phenyl-4-substituted-β-carbolines via iodine-mediated electrophilic cyclization as key step were synthesized and their inhibitory activity against three tumor cell lines was evaluated in vitro. It wa... 详细信息

关键词： β-Carboline Synthesis Iodine-mediated cyclization Cytotoxicity Harmine

Latamoxef-induced severe thrombocytopenia during the treatment of pulmonary infection:A case report

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World Journal of Clinical Cases 2022年第22期10卷 7906-7912页

作者： Ruo-ying Zhang Jun-Jie Zhang Jin-Meng Li ying-ying xu Yue-Huan xu Xin-Jun Cai Department of Pharmacy Affiliated Hangzhou Chest HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Out-patient Zhejiang Medical and Health Group Hangzhou HospitalHangzhou 310000Zhejiang ProvinceChina Tuberculosis Treatment Centre Affiliated Hangzhou Chest HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina

BACKGROUND Latamoxef shows excellent antibacterial activity against anaerobic bacteria such as Bacteroides *** of thrombocytopenic toxicity of latamoxef are *** report presents a case of severe thrombocytopenia possibly induced by latamoxef,an infrequent adverse drug reaction in a young patient with tuberculosis and Crohn's disease in *** SUMMARY We reported a case of severe thrombocytopenia induced by latamoxef in a 28-year-old man with tuberculosis and Crohn's *** admission,the patient presented with a cough productive of bloody sputum,a chest computed tomogram suggested scattered mottled,high-density shadows in both *** tests indicated a platelet count of 140000/μ*** a pulmonary bacterial infection,the patient received anti-infection therapy with latamoxef(dose:2.0 g)intravenously *** the 9th day of treatment,the platelet count decreased to 44000/μ*** the 12th day,scattered purpura and ecchymosis appeared on the patient’s limbs and trunk,and the platelet count decreased to 9000/μL after latamoxef treatment for 15 *** days after discontinuation of latamoxef,the platelet count recovered to 157000/μL,and the area of scattered purpura and ecchymosis on the limbs and trunk *** platelet counts remained in the normal range,and no thrombocytopenia was found at follow-up 15 mo after *** For patients treated with latamoxef,platelet counts should be carefully followed,and caregivers should be vigilant for the appearance of scattered ecchymosis.

关键词： Thrombocytopenia Latamoxef Adverse drug reactions Young onset Case report

Risk factors for lymph node metastasis and evaluation of reasonable surgery for early gastric cancer

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World Journal of Gastroenterology 2007年第38期13卷 5133-5138页

作者： ying-ying xu Bao-Jun Huang Zhe Sun Chong Lu Yun-Peng Liu Department of Medical Oncology First Hospital of China Medical University Shenyang 110001 Liaoning Province China Department of Surgical Oncology First Hospital of China Medical University Shenyang 110001 Liaoning Province China

AIM: To give the evidence for rationalizing surgical therapy for early gastric cancer with different lymph node status. METHODS: A series of 322 early gastric cancer patients who underwent gastrectomy with more than 15 lymph nodes retrieved were reviewed in this study. The rate of lymph node metastasis was calculated. Univariate and multivariate analyses were performed to evaluate the independent factors for predicting lymph node metastasis. RESULTS: No metastasis was detected in No.5, 6 lymph nodes (LN) during proximal gastric cancer total gastrectomy, and in No.10, 11p, 11d during for combined resection of spleen and splenic artery and in No.15 LN during combined resection of transverse colon mesentery. No.11p, 12a, 14v LN were proved negative for metastasis. The global metastastic rate was 14.6% for LN, 5.9% for mucosa, and 22.4% for submucosa carcinoma, respectively. The metastasis in group Ⅱ?was almost limited in No.7, 8a LN. Multivariate analysis identified that the depth of invasion, histological type and lymphatic invasion were independent risk factors for LN metastasis. No metastasis from distal cancer (≤ 1.0 cm in diameter) was detected in group Ⅱ?LN. The metastasis rate increased significantly when the diameter exceeded 3.0 cm. All tumors (≤ 1.0 cm in diameter) with LN metastasis and mucosa invasion showed a depressed macroscopic type, and all protruded carcinomas were > 3.0 cm in diameter. CONCLUSION: Segmental/subtotal gastrectomy plus D1/D1 + No.7 should be performed for carcinoma (≤ 1.0 cm in diameter, protruded type and mucosa invasion).Subtotal gastrectomy plus D2 or D1 + No.7, 8a, 9 is the most rational operation, whereas No.11p, 12a, 14v lymphadenectomy should not be recommended routinely for poorly differentiated and depressed type of submucosa carcinoma (> 3.0 cm in diameter). Total gastrectomy should not be performed in proximal, so does combined resection or D2+/D3 lymphadenectomy.

关键词： Lymph node Metastasis Surgery Early gastric cancer