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Science Bulletin 2024年第2期69卷 159-162页

作者： Si-Yuan Yu yi-li liu Zheng li Dechen Jiang Jing-Juan Xu Hong-Yuan Chen Wei-Wei Zhao State Key Laboratory of Analytical Chemistry for life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China

Nanoelectrodes have been shown to be powerful tools for nanoscopic research on single entities,deepening the understanding of heterogeneity and stochastics for single molecules,nanoparticles and cells[1–3].However,despite their importance,current nanoelectrode preparations are highly restrained to flame/electrochemical etching,metal sputtering,electrochemical deposition,etc.[3],resulting in a limited range of materials(mainly gold,platinum and carbon)for potential-resolved detection of redox-active species(Table S1 online).The enrichment of preparation methods to introduce novel materials and mechanisms should prove significant for the development of nanoelectrodes.

关键词： electrode deepening restrained

Ultrahigh thermoelectric properties of p‐type Bi_(x)Sb_(2−x)Te_(3)thin films with exceptional flexibility for wearable energy harvesting

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Carbon Energy 2024年第8期6卷 273-284页

作者： Zhuang‐Hao Zheng yi‐Ming Zhong yi‐liu li Mohammad Nisar Adil Mansoor Fu li Shuo Chen Guang‐Xing liang Ping Fan Dongyan Xu Meng Wei Yue‐Xing Chen Shenzhen Key Laboratory of Advanced Thin Films and Applications Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong ProvinceCollege of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhenChina Department of Mechanical and Automation Engineering The Chinese University of Hong KongSha TinChina

Use of a flexible thermoelectric source is a feasible approach to realizing selfpowered wearable electronics and the Internet of *** thin films are promising candidates for fabricating flexible power supply,but obtaining highthermoelectric‐performance thin films remains a big *** the present work,a p‐type Bi_(x)Sb_(2−x)Te_(3)thin film is designed with a high figure of merit of 1.11 at 393 K and exceptional flexibility(less than 5%increase in resistance after 1000 cycles of bending at a radius of∼5 mm).The favorable comprehensive performance of the Bi_(x)Sb_(2−x)Te_(3)flexible thin film is due to its excellent crystallinity,optimized carrier concentration,and low elastic modulus,which have been verified by experiments and theoretical ***,a flexible device is fabricated using the prepared p‐type Bi_(x)Sb_(2−x)Te_(3)and n‐type Ag_(2)Se thin ***,an outstanding power density of∼1028μWcm^(−2)is achieved at a temperature difference of 25 *** work extends a novel concept to the fabrication of highperformance flexible thin films and devices for wearable energy harvesting.

关键词： Bi_(x)Sb_(2−x)Te_(3) electrical transport properties flexibility thermoelectric

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周围神经过度兴奋综合征临床特征分析

中国现代神经疾病杂志 2024年第5期24卷 375-381页

作者：梅文丽李六一冯淑艳张杰文河南省人民医院郑州大学人民医院神经电生理科 450003 河南省人民医院郑州大学人民医院神经内科 450003

目的总结周围神经过度兴奋综合征临床特征。方法与结果纳入河南省人民医院2018年10月至2022年4月收治的10例周围神经过度兴奋综合征患者,临床表型为Morvan综合征5例、Issacs综合征4例、痉挛-束颤综合征1例;临床表现为肌颤搐10例、自... 详细信息

目的总结周围神经过度兴奋综合征临床特征。方法与结果纳入河南省人民医院2018年10月至2022年4月收治的10例周围神经过度兴奋综合征患者,临床表型为Morvan综合征5例、Issacs综合征4例、痉挛-束颤综合征1例;临床表现为肌颤搐10例、自主神经功能障碍8例、中枢神经系统症状7例、肢体无力7例、感觉障碍6例、痉挛和肌肉僵硬2例;5例自身抗体阳性;2例MRI异常,分别位于脑干、左侧枕叶和右侧丘脑;10例肌电图异常,表现为F波后发放电位10例、异常自发运动单位电位10例、束颤电位10例、肌颤搐电位8例、神经性肌强直电位3例;3例仅行对症治疗,7例行对症治疗及免疫调节治疗;1例失访,5例预后良好,2例预后不良,2例死亡。结论周围神经过度兴奋综合征临床表现具有异质性,神经电生理检出后发放电位可能是诊断周围神经过度兴奋综合征的敏感性指标。

关键词：周围神经系统疾病神经系统自身免疫疾病肌纤维颤搐肌电描记术

In-situ polymerized PEO-based solid electrolytes contribute better li metal batteries:Challenges,strategies,and perspectives

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Journal of Energy Chemistry 2024年第5期92卷 548-571页

作者： Zhihui Jia Yong liu Haoming li yi Xiong yingjie Miao Zhongxiu liu Fengzhang Ren School of Materials Science and Engineering Henan Key Laboratory of Non-Ferrous Materials Science&Processing TechnologyHenan University of Science and TechnologyLuoyang 471023HenanChina Provincial and Ministerial Co-construction of Collaborative Innovation Center for Non-ferrous Metal new Materials and Advanced Processing Technology Henan University of Science and TechnologyLuoyang 471023HenanChina

Polyethylene oxide(PEO)-based solid polymer electrolytes(SPEs)with good electrochemical stability and excellent li salt solubility are considered as one of the most promising SPEs for solid-state lithium metal batteries(SSLMBs).However,PEO-based SPEs suffer from low ionic conductivity at room temperature and high interfacial resistance with the electrodes due to poor interfacial contact,seriously hindering their practical *** an emerging technology,in-situ polymerization process has been widely used in PEO-based SPEs because it can effectively increase li-ion transport at the interface and improve the interfacial contact between the electrolyte and ***,we review recent advances in design and fabrication of in-situ polymerized PEO-based SPEs to realize enhanced performance in *** merits and current challenges of various SPEs,as well as their stabilizing strategies are ***,various in-situ polymerization methods(such as free radical polymerization,cationic polymerization,anionic polymerization)for the preparation of PEO-based SPEs are *** addition,the application of in-situ polymerization technology in PEO-based SPEs for adjustment of the functional units and addition of different functional filler materials was systematically discussed to explore the design concepts,methods and working ***,the challenges and future prospects of in-situ polymerized PEO-based SPEs for SSLMBs are also proposed.

关键词： In-situ polymerization Polyethylene oxide Solid polymer electrolytes lithium metal anodes

Comparison of the spatial and temporal variability of macroinvertebrate and periphyton-based metrics in a macrophyte-dominated shallow lake

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Frontiers of Earth Science 2015年第1期9卷 137-151页

作者： Lulu ZHANG Jingling liu yi li State Key Joint Laboratory of Environmental Simulation and Pollution Control School of Environment Beijing Normal University Beijing 100875 China

The influence of spatial differences, which are caused by different anthropogenic disturbances, and temporal changes, which are caused by natural conditions, on macroinvertebrates with periphyton communities in Baiyangdian Lake was compared. Periphyton and macrobenthos assemblage samples were simultaneously col- lected on four occasions during 2009 and 2010. Based on the physical and chemical attributes in the water and sediment, the 8 sampling sites can be divided into 5 habitat types by using cluster analysis. According to coefficients variation analysis （CV）, three primary conclusions can be drawn ：（1） the metrics of Hilsenhoff Biotic Index （HBI）, Percent Tolerant Taxa （PTT）, Percent dominant taxon （PDT）, and community loss index （Cli）, based on macroinvertebrates, and the metrics of algal density （AD）, the proportion of chlorophyta （CHL）, and the proportion of cyanophyta （CYA）, based on periphytons, were mostly constant throughout our study; （2） in terms of spatial variation, the CV values in the macroinvertebratebased metrics were lower than the CV values in the periphyton-based metrics, and these findings may be caused by the effects of changes in environmental factors; whereas, the CV values in the macroinvertebrate-based metrics were higher than those in the periphyton-based metrics, and these results may be linked to the influences of phenology and life history patterns of the macroinvertebrate individuals; and （3） the CV values for the functionalbased metrics were higher than those for the structuralbased metrics. Therefore, spatial and temporal variation for metrics should be considered when assessing applying the biometrics.

关键词： Baiyangdian Lake biomonitoring coefficient variation structural metrics functional metrics

F-doped orthorhombic Nb_(2)O_(5) exposed with 97% (100) facet for fast reversible liþ-Intercalation

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Green Energy & Environment 2024年第4期9卷 723-731页

作者： Xiaodi liu Yufeng Tang Dan Zhang Guangyin liu Xinwei Luo yi Shang Xiu li Jianmin Ma College of Chemistry and Pharmaceutical Engineering Nanyang Normal UniversityNanyang473061China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu611731China

Orthorhombic Nb_(2)O_(5)(T-Nb_(2)O_(5))is attractive for fast-charging li-ion batteries,but it is still hard to realize rapid charge transfer kinetics for li-ion ***,F-doped T-Nb_(2)O_(5) microﬂowers(F-Nb_(2)O_(5))are rationally synthesized through topotactic ***,F-Nb_(2)O_(5) are assembled by single-crystal nanoﬂakes with nearly 97%exposed(100)facet,which maximizes the exposure of the feasible li^(+)transport pathways along loosely packed 4g atomic layers to the electrolytes,thus effectively enhancing the li^(+)-intercalation ***,the band gap of F-Nb_(2)O_(5) is reduced to 2.87 eV due to the doping of F atoms,leading to enhanced electrical *** synergetic effects between tailored exposed crystal facets,F-doping,and ultrathin building blocks,speed up the li^(+)/electron transfer kinetics and improve the pseudocapacitive properties of F-Nb_(2)O_(5).Therefore,F-Nb_(2)O_(5) exhibit superior rate capability(210.8 and 164.9 mAh g^(-1) at 1 and 10 C,respectively)and good long-term 10 C cycling performance(132.7 mAh g^(-1) after 1500 cycles).

关键词： Exposed facets Orthorhombic Nb_(2)O_(5) F-doping Pseudocapacitive intercalation anode li-ion storage

A Possible 456-Day Optical Period of OQ 530

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Chinese Journal of Astronomy and Astrophysics 2007年第3期7卷 380-388页

作者： yi liu Juan li Jun-Hui Fan Center for Astrophysics Guangzhou University Guangzhou 510006

The post-1994 observations of the blazar OQ 530 in optical BVRI bands, and radio observations at 22 GHz and 37 GHz were collected. The date compensated discrete Fourier transform （DCDFr） and CLEANest methods were used to search for possible periodicities. Two possible periods of 456±100 days and 258±29 days were found in the optical bands. The existence of possible correlations between the optical and radio emissions was investigated by means of discrete correlation function （DCF） analysis, and no significant correlation was found. Some possible mechanisms for the periodic variability are discussed.

关键词： galaxies active - BL Lacertae objects general - BL Lacertae objects indi-vidual OQ 530

Migration characteristics of neural stem cells for glioma cells in vivo and in vitro

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Neural Regeneration Research 2011年第1期6卷 12-17页

作者： Jianxiong liu yi Zhang Haixia liu li Qiao Xiaolan Xie Department of Neurosurgery Gansu Provincial People's Hospital Lanzhou 730000 Gansu Province China

This study analyzed migration characteristics of neural stem cells （NSCs） in vitro and in vivo, as well as exogenous gene expression in the brain following transfection of NSCs with an enhanced green fluorescent protein （EGFP） gene expression vector plRES2-EGFP plasmid, in glioma experimental models. NSCs slowly migrated towards glioma cells （C6 cells） in culture, although mouse embryonic fibroblasts 3T3 cells did not migrate. NSCs rapidly migrated to the tumor bed, and to tissues surrounding the tumor and metastatic lesions. A large number of EGFP-expressing cells formed distinct colonies in and surrounding the tumor following NSCs-EGFP transfection. EGFP-positive cells aggregated in incubation sites following 3T3-EGFP treatment. Results suggested that NSCs could be used to track tumor cells in vitro. In vivo, transplanted NSCs survived expressed transfected exogenous genes, migrated to the tumor bed, and expressed exogenous genes.

关键词： glioma stem cells gene transfection tracing migration

集成电路封装设计领域中一种高精度泪滴生成方法研究

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中国集成电路 2024年第9期33卷 56-62页

作者：吴声誉朱俊辉刘伊力上海弘快科技有限公司

本文旨在应对集成电路封装设计领域中泪滴形成的高精度挑战,在探讨集成电路芯片封装过程中对于印刷电路板生产领域内泪滴技术存在的局限性进行深入分析的基础上,本文提出了一项提高泪滴形成精确度的新型方法。该技术在泪滴特性配置、初... 详细信息

本文旨在应对集成电路封装设计领域中泪滴形成的高精度挑战,在探讨集成电路芯片封装过程中对于印刷电路板生产领域内泪滴技术存在的局限性进行深入分析的基础上,本文提出了一项提高泪滴形成精确度的新型方法。该技术在泪滴特性配置、初步处理、核心程序决策、准则操控等领域实现了重要进展,达到了泪滴构造的微观尺度精确度。本研究在技术层面展现了独创性并且在实践操作中显示了高效能、稳定性佳等优点,拥有宽广的商业成长空间。

关键词：集成电路封装设计泪滴生成方法 EDA行业高精度设计

The role of TRPC6 in HGF-induced cell proliferation of human prostate cancer DU145 and PC3 cells

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Asian Journal of Andrology 2010年第6期12卷 841-852页

作者： Yong Wang Dan Yue Kai li yi-li liu Chang-Shah Ren Ping Wang Department of Urology Fourth Affiliated Hospital China Medical University Shenyang 110032 China College of Medical Laboratory Science Tianjin Medical University Tianjin 300070 China Department of Surgical Oncology First Affiliated Hospital China Medical University Shenyang 110001 China Cancer Research Institute First Affiliated Hospital China Medical University Shenyang 110001 China

Hepatocyte growth factor （HGF） is a glycoprotein that induces prostate cancer cell proliferation, migration and invasion. The activation of transient receptor potential canonical 6 （TRPC6） channels is considered important in promoting prostate cancer cell proliferation. In this study, we assessed the role of endogenous TRPC6 channels in the HGF-induced cell proliferation of prostate cancer. Reverse transcription-PCR and Western blotting were used to investigate TRPC6 expression. Electrophysiological techniques （whole-cell patch clamp configuration） and Ca^2＋ imaging analysis were used to investigate the channel activity in cells. The effects of TRPC6 channels on cell cycle progression, cell apoptosis and cell growth were also examined. TRPC6 and c-MET were expressed in DU145 and PC3 cells. In addition, functional TRPC6 channels were present in DU145 and PC3 cells, and TRPC6 knockdown suppressed TRPC-Iike currents evoked by oleoyl-2-acetyl-sn-glycerol （OAG）. Inhibition of TRPC6 channels in DU145 and PC3 cells abolished OAG- and HGF-induced Ca^2＋ entry. Furthermore, inhibition of TRPC6 channels arrested DU145 and PC3 cells at the G2/M phase and suppressed HGF-induced cell proliferation. Collectively, our results indicate that TRPC6 has an important role in HGF-induced DU145 and PC3 cell proliferation.

关键词： hepatocyte growth factor human prostate cancer proliferation TRPC6