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数字化赋能农信系统发展的路径、问题与对策研究

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内蒙古科技与经济 2024年第2期 74-79页

作者：贾雅茹尚妤集宁师范学院经济管理学院内蒙古乌兰察布012000

数字化转型是纾解农村金融困境、推动农信系统高质量发展的必由之路。文章基于农信系统依托金融科技助力乡村振兴的现状,通过梳理数字化赋能农信系统发展的机制路径,剖析农信系统在数字化转型过程中存在的关键问题,进而有针对性地从统... 详细信息

数字化转型是纾解农村金融困境、推动农信系统高质量发展的必由之路。文章基于农信系统依托金融科技助力乡村振兴的现状,通过梳理数字化赋能农信系统发展的机制路径,剖析农信系统在数字化转型过程中存在的关键问题,进而有针对性地从统筹共享数字资源、差异化定位转型战略、建立健全监管体系、加强数字人才队伍建设等方面提出相应的对策建议,以期为数字技术高效赋能农信系统提供参考借鉴。

关键词：数字化赋能农信系统机制路径对策建议

Construction of AIEgen functionalized nanomicelles and their stability study through‘seesaw-like'fluorescence changes

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Chinese Chemical Letters 2023年第6期34卷 382-386页

作者： Xiaotong Wang Shizhu Chen yaru jia Kaihan Zhang Lili Ma Luwei Li Xingjie Liang Jinchao Zhang College of Chemistry and Environmental Science Chemical Biology Key Laboratory of Hebei ProvinceKey Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of EducationHebei UniversityBaoding 071002China CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in NanoscienceNational Center for Nanoscience and Technology of ChinaBeijing 100190China Department of Chemistry The University of ManchesterManchester M139PLUnited Kingdom

As nanocarriers,nanomicelles play vital roles in the toolbox of drug *** stability of nanomicelles affects the nanomedicines'***,it is important to understand the stability of nanomicelles for further ***,we report a strategy to construct new nanomicelles(NM)by introducing aggregation-induced emission(AIE)functional group tetraphenylethylene(TPE)in the component polymer vitamin E(D-α-tocopheryl polyethylene glycol 1000 succinate)(TPGS).The stability of doxorubicin(DOX)loaded nanomicelles DOX@NM in different conditions was studied by fluorescence *** fluorescence changes of DOX@NM are‘seesaw-like'when they transform between assembled and disassembled *** the assembled form,TPE gives emission from AIE effect,while in the disassembled form,the fluorescence of DOX is observed due to the disappearance of ACQ effect.

关键词： Polymer nanomicelles Aggregation-induced emission Fluorescence ratio Stability Drug delivery system

The Yin and Yang of the protein corona on the delivery journey of nanoparticles

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Nano Research 2023年第1期16卷 715-734页

作者： Yi-Feng Wang Yaxin Zhou jiaBei Sun Xiaotong Wang yaru jia Kun Ge Yan Yan Kenneth A.Dawson Shutao Guo Jinchao Zhang Xing-Jie Liang Guangdong Provincial Education Department Key Laboratory of Nano-Immunoregulation Tumor Microenvironment Guangzhou Key Laboratory for Research and Development of Nano-Biomedical Technology for Diagnosis and Therapythe Second Affiliated HospitalGuangzhou Medical UniversityGuangzhou 510260China Chinese Academy of Sciences(CAS)Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in NanoscienceNational Center for Nanoscience and Technology of ChinaBeijing 100190China Key Laboratory of Functional Polymer Materials of Ministry of Education State Key Laboratory of Medicinal Chemical Biology and Institute of Polymer ChemistryCollege of ChemistryNankai UniversityTianjin 300071China China National Institute of Food and Drug Control Beijing 100061China Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education Key Laboratory of Chemical Biology of Hebei ProvinceCollege of Chemistry and Environmental ScienceHebei UniversityBaoding 071002China Centre for BioNano Interactions School of ChemistrySchool of Biomolecular and Biomedical ScienceUniversity College DublinDublin D04V1W8Ireland

Nanoparticles-based drug delivery systems have attracted significant attention in biomedical fields because they can deliver loaded cargoes to the target site in a controlled ***,tremendous challenges must still be overcome to reach the expected targeting and therapeutic efficacy in *** challenges mainly arise because the interaction between nanoparticles and biological systems is complex and dynamic and is influenced by the physicochemical properties of the nanoparticles and the heterogeneity of biological ***,once the nanoparticles are injected into the blood,a protein corona will inevitably form on the *** protein corona creates a new biological identity which plays a vital role in mediating the bio–nano interaction and determining the ultimate ***,it is essential to understand how the protein corona affects the delivery journey of nanoparticles in vivo and what we can do to exploit the protein corona for better delivery *** this review,we first summarize the fundamental impact of the protein corona on the delivery journey of ***,we emphasize the strategies that have been developed for tailoring and exploiting the protein corona to improve the transportation behavior of nanoparticles in ***,we highlight what we need to do as a next step towards better understanding and exploitation of the protein *** hope these insights into the“Yin and Yang”effect of the protein corona will have profound implications for understanding the role of the protein corona in a wide range of nanoparticles.

关键词： protein corona nanoparticles biological identity drug delivery bio-nano interaction

Extending Structures for Gel'fand-Dorfman Bialgebras

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Acta Mathematica Sinica,English Series 2024年第2期40卷 619-638页

作者： jia jia WEN Yan Yong HONG School of Mathematics Hangzhou Normal UniversityHangzhou 311121P.R.China

Gel'fand-Dorfman bialgebra,which is both a Lie algebra and a Novikov algebra with some compatibility condition,appeared in the study of Hamiltonian pairs in completely integrable *** also emerged in the description of a class special Lie conformal algebras called quadratic Lie conformal *** this paper,we investigate the extending structures problem for Gel'fand-Dorfman bialgebras,which is equivalent to some extending structures problem of quadratic Lie conformal ***,given a Gel'fand-Dorfman bialgebra(A,o,[.,.]),this problem is how to describe and classify all Gel'fand-Dorfman bialgebra structures on a vector space E(A⊂E)such that(A,o,[.,.])is a subalgebra of E up to an isomorphism whose restriction on A is the identity *** by the theories of extending structures for Lie algebras and Novikov algebras,we construct an object gH2(V,A)to answer the extending structures problem by introducing the notion of a unified product for Gel'fand-Dorfman bialgebras,where V is a complement of A in *** particular,we investigate the special case when dim(V)=1 in detail.

关键词： Gel'fand-Dorfman bialgebra Lie conformal algebra Extending structures problem Novikovalgebra

Geometric Constraints for Global Regularity of 3D Shear Thickening Fluids

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Acta Mathematicae Applicatae Sinica 2024年第1期40卷 205-210页

作者： jia-qi Yang Research&Development Institute of Northwestern Polytechnical University in Shenzhen Shenzhen518063China Key Laboratory for Mechanics in Fluid Solid Coupling Systems Institute of MechanicsChinese Academy of SciencesBeijing100190China

We consider the relation between the direction of the vorticity and the global regularity of 3D shear thickening *** is showed that a weak solution to the non-Newtonian incompressible fluid in the whole space is stron... 详细信息

关键词： direction of the vorticity non-Newtonian fluid global regularity

Two-dimensional ballistic transistors for advanced-node integrated circuits

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National Science Review 2024年第3期11卷 9-10页

作者： jia Li Xidong Duan Hunan Provincial Key Laboratory of Two-Dimensional Materials State Key Laboratory for Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering Hunan University

As the feature size of metal-oxide-semiconductor-field-effect-transistors(MOSFETs) in integrated circuits(ICs)is reduced to sub-10-nm, the traditional channel materials are plagued by enhanced scattering and short-cha... 详细信息

关键词： CONTACT

Numerical analysis of the correlation between fluid dynamic modes and hydrodynamic noise in flows around a three-dimensional circular cylinder

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Journal of Hydrodynamics 2024年第1期36卷 119-129页

作者： jia-jia Qin Ming-xin Zou Yuan Zhuang De-cheng Wan Computational Marine Hydrodynamics Lab(CMHL) School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai200240China Wuhan Second Ship Design and Research Institute Wuhan430205China

The flow around a circular cylinder for Re=1000 is characterized by flow separation and Karman vortex *** typical flow features can be captured to study the correlation between fluid fields and sound *** this paper,the three-dimensional circular cylinder is taken as the research object,and the probes of surface fluctuating pressure and far field sound pressure are arranged every 10°.The directional diagram and the coherence of fluctuating pressure and sound pressure are *** relationship between the flow mode and hydrodynamic noise is studied by using dynamic mode decomposition(DMD).The characteristics of the dipole and quadrupole sound source term of a long span cylinder are *** results show that at the angles between 30°–120°and 190°–350°,the fluctuating pressure contributes more to the generation of dipole *** quadrupole sound source shows three-dimensional effects,which is more obvious in a cylinder with large spanwise length.

关键词： Pressure coherence dynamic mode decomposition flow-sound correlation circular cylinder

Facile synthesis of transition metal complexes with five coplanar metal-carbon σ-bonds

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National Science Review 2024年第4期11卷 11-12页

作者： Guocheng jia Department of Chemistry Hong Kong University of Science and Technology

Carbon is one of the most important elements in chemistry, forming a vast number of organic compounds. It can also form a variety of organometallic compounds with a metal–carbon bond. Metal alkyl, carbene and carbyne complexes are classical examples of organometallic compounds. A particularly interesting class of organometallic compounds are all-carbon metallacycles formed by combination of a metal and a hydrocarbon chain serving as a chelating agent with only carbon atoms as the donor atoms. Many interesting monocyclic metallacycles made of a chelating bidentate hydrocarbon chain are known, for example, metallacyclobutadienes, metallacyclopentadienes and metallabenzenes[1].

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Structural engineered living materials

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Nano Research 2024年第2期17卷 715-733页

作者： Yang Geng Zian jia Ling Li 635 Prices Fork Road Department of Mechanical EngineeringVirginia Polytechnic Institute and State UniversityBlacksburg VA24061USA

Biological structural materials not only exhibit remarkable mechanical properties but also often embody dynamic characteristics such as environmental responsiveness,autonomy,and self-healing,which are difficult to achieve in conventional engineering *** merging materials science,synthetic biology,and other disciplines,engineered living materials(ELMs)provide a promising solution to combine living organisms with abiotic components,thus facilitating the construction of functional“living”*** natural materials,ELMs possess vitality and hold immense application potential in areas such as medicine,electronics,and construction,captivating increasing research attention *** an emerging branch of ELMs,structural ELMs aim to mimic living biological structural materials by achieving desired mechanical performance while maintaining important“living”*** we summarize the recent progress and provide our perspectives for this emerging research *** first summarize the superiority of structural ELMs by reviewing biological structural materials and biomimetic material design ***,we provide a systematic discussion on the definition and classifications of structural ELMs,their mechanical performance,and physiological ***,we summarize some critical challenges faced by structural ELMs and highlight directions of future *** hope this review article can provide a timely summary of the state of the art and relevant perspectives for future development of structural ELMs.

关键词： structural materials engineered living materials(ELMs) structural ELMs composites mechanical properties