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MXene based mechanically and electrically enhanced film for triboelectric nanogenerator

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Nano Research 2021年第12期14卷 4833-4840页

作者： Yuyu Gao Guoxu liu Tianzhao Bu yaoyao liu Youchao Qi Yanting Xie Shaohang Xu Weili Deng Weiqing Yang Chi Zhang CAS Center for Excellence in Nanoscience Beijing Key Laboratory of Micro-nano Energy and SensorBeijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing101400China Key Laboratory of Advanced Technologies of Materials(Ministry of Education) School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu610031China School of Nanoscience and Technology University of Chinese Academy of SciencesBeijing100049China Center on Nanoenergy Research School of Physical Science and TechnologyGuangxi UniversityNanning530004China

The development of triboelectric nanogenerator(TENG)technology which can directly convert ambient mechanical energy into electric energy may affect areas from green energy harvesting to emerging wearing ***,the material of triboelectric layer is critical to the mechanical robustness and electrical output characteristics of the ***,a MXene enhanced electret polytetrafluoroethylene(PTFE)film with a high mechanical property and surface charge density is *** MXene/PTFE composite film was synthesized by spraying and annealing *** the doping of MXene,the crystallinity of composite film could be tuned,leading to an enhancement in the tensile property of 450%and reducing the wear volume about 80%in the friction ***,the as-fabricated TENG with this composite film outputs 397 V of open-circuit voltage,21µA of short-circuit current,and 232 nC of transfer charge quantity,which are 4,6,and 6 times higher than that of the TENG made by pure PTFE film,***,this work provides a creative strategy to simultaneously improve the mechanical property and electrical performance of the TENGs,which have great potential in improving device stability under a complex mechanical environment.

关键词： MXene polytetrafluoroethylene(PTFE) mechanically and electrically enhanced triboelectric layer triboelectric nanogenerator

The Synergism between Methanogens and Methanotrophs and the Nature of their Contributions to the Seasonal Variation of Methane Fluxes in a Wetland:The Case of Dajiuhu Subalpine Peatland

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Advances in Atmospheric Sciences 2022年第8期39卷 1375-1385,I0017-I0023页

作者： Luwen WANG Jiwen GE Liang FENG yaoyao liu Yu LI Jiumei WANG Xiang XIAO Zhiqi ZHANG Laboratory of Basin Hydrology and Wetland Eco-Restoration China University of GeosciencesWuhan 430074China Hubei Key Laboratory of Wetland Evolution and Ecological Restoration China University of GeosciencesWuhan 430074China Institution of Ecology and Environmental Sciences China University of GeosciencesWuhan 430074China Shennongjia National Park Administration Bureau Shennongjia Forestry District 442417China

Wetland ecosystems are the most important natural methane(CH_(4))sources,whose fluxes periodically ***(methane producers)and methanotrophs(methane consumers)are considered key factors affecting CH_(4)fluxes in ***,the symbiotic relationship between methanogens and methanotrophs remains *** help close this research gap,we collected and analyzed samples from four soil depths in the Dajiuhu subalpine peatland in January,April,July,and October 2019 and acquired seasonal methane flux data from an eddy covariance(EC)system,and investigated relationships.A phylogenetic molecular ecological networks(pMENs)analysis was used to identify keystone species and the seasonal variations of the co-occurrence patterns of methanogenic and methanotrophic *** results indicate that the seasonal variations of the interactions between methanogenic and methanotrophic communities contributed to CH_(4)emissions in *** keystone species discerned by the network analysis also showed their importance in mediating CH_(4)***(CH_(4))emissions in wetlands were lowest in spring;during this period,the most complex interactions between microbes were observed,with intense competition among methanogens while methanotrophs demonstrated better *** patterns manifested themselves in summer when the highest CH_(4)flux was *** formicica was negatively correlated with CH_(4)fluxes and occupied the largest ecological niches in the spring *** contrast,both Methanocella arvoryzae and Methylocystaceae demonstrated positive correlations with CH_(4)fluxes and were better adapted to the microbial community in the *** addition,soil temperature and nitrogen were regarded as significant environmental factors to CH_(4)*** study was successful in explaining the seasonal patterns and microbial driving mechanisms of CH_(4)emissions in wetlands.

关键词： CH_(4)fluxes wetland methanogens methanotrophs molecular ecological network

Nanomaterial-based microelectrode arrays for in vitro bidirectional brain–computer interfaces:a review

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Microsystems & Nanoengineering 2023年第1期9卷 55-72页

作者： yaoyao liu Shihong Xu Yan Yang Kui Zhang Enhui He Wei Liang Jinping Luo Yirong Wu Xinxia Cai State Key Laboratory of Transducer Technology Aerospace Information Research InstituteChinese Academy of SciencesBeijing100190China School of Electronic Electrical and Communication EngineeringUniversity of Chinese Academy of SciencesBeijing100049PR China

A bidirectional in vitro brain–computer interface(BCI)directly connects isolated brain cells with the surrounding environment,reads neural signals and inputs modulatory *** a noninvasive BCI,it has clear advantages in understanding and exploiting advanced brain function due to the simplified structure and high controllability of ex vivo neural ***,the core of ex vivo BCIs,microelectrode arrays(MEAs),urgently need improvements in the strength of signal detection,precision of neural modulation and ***,nanomaterial-based MEAs cater to all the requirements by converging the multilevel neural signals and simultaneously applying stimuli at an excellent spatiotemporal resolution,as well as supporting long-term cultivation of *** is enabled by the advantageous electrochemical characteristics of nanomaterials,such as their active atomic reactivity and outstanding charge conduction efficiency,improving the performance of ***,we review the fabrication of nanomaterial-based MEAs applied to bidirectional in vitro BCIs from an interdisciplinary *** also consider the decoding and coding of neural activity through the interface and highlight the various usages of MEAs coupled with the dissociated neural cultures to benefit future developments of BCIs.

关键词： modulator neural computer

Wireless closed-loop deep brain stimulation using microelectrode array probes

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第10期25卷 803-823页

作者： Qianli JIA yaoyao liu Shiya LV Yiding WANG Peiyao JIAO Wei XU Zhaojie XU Mixia WANG Xinxia CAI State Key Laboratory of Transducer Technology Aerospace Information Research InstituteChinese Academy of SciencesBeijing 100190China School of Electronic Electrical and Communication EngineeringUniversity of Chinese Academy of SciencesBeijing 100049China

Deep brain stimulation(DBS),including optical stimulation and electrical stimulation,has been demonstrated considerable value in exploring pathological brain activity and developing treatments for neural *** in DBS microsystems based on implantable microelectrode array(MEA)probes have opened up new opportunities for closed-loop DBS(CL-DBS)in *** technology can be used to detect damaged brain circuits and test the therapeutic potential for modulating the output of these circuits in a variety of diseases *** the success and rapid utilization of MEA probe-based CL-DBS microsystems,key challenges,including excessive wired communication,need to be urgently *** this review,we considered recent advances in MEA probe-based wireless CL-DBS microsystems and outlined the major issues and promising prospects in this *** technology has the potential to offer novel therapeutic options for psychiatric disorders in the future.

关键词： Deep brain stimulation(DBS) Wireless closed-loop deep brain stimulation(CL-DBS)microsystem Microelectrode array(MEA)probe Optical stimulation Electrical stimulation

Cinnamon free phenolic extract regulates glucose absorption in intestinal cells by inhibiting glucose transporters

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Food Bioscience 2023年第2期52卷 479-487页

作者： yaoyao liu Daorui Pang Dongxu Xing Weifei Wang Qian Li Sentai Liao Erna Li Yuxiao Zou Sericultural&Agri-Food Research Institute Guangdong Academy of Agricultural SciencesKey Laboratory of Functional FoodsMinistry of Agriculture and Rural AffairsGuangdong Key Laboratory of Agricultural Products ProcessingGuangzhou510610GuangdongChina

Cinnamon is a traditional herbal medicine that is a valuable source of bioactive phenolic *** this study,we determined the effects of cinnamon free phenolic extract(CFPE)on glucose transport in Caco-2 cells and its possible mechanisms of ***,the contents of phenolic compounds and flavonoids in bark were compared among four cinnamon ***‘Taiwan’cultivar had the highest contents of these compounds,and the CFPE was prepared from it.A Caco-2 monolayer was established,and the effect of CFPE on glucose transport across the monolayer was *** results showed that CFPE(at 150-300μg/mL)suppressed glucose transport across the monolayer in a dose-dependent *** C1,procyanidin B2,procyanidin B1,procyanidin B3,procyanidin A2,and(􀀀)-epicatechin derivatives in CFPE may have contributed to its suppressive *** with CFPE decreased the transcript levels of SGK1 encoding serum and glucocorticoid-inducible kinase and PLC/PKC encoding phospholipase C/protein kinase C,which are involved in the signaling pathway associated with glucose transport;and the transcript levels of SGLT1 encoding sodium/glucose cotransporter 1 and GLUT2 encoding glucose transporter 2,the key glucose transporters in this *** findings suggest that CFPE inhibits glucose transport via its effects on the signaling pathway and glucose transporters involved in glucose absorption in intestinal ***,CFPE has potential applications in preventing postprandial hyperglycemia.

关键词： Cinnamon free phenolic extract Glucose uptake and transport SGLT1 GLUT2

Simulation and fabrication of in vitro microfluidic microelectrode array chip for patterned culture and electrophysiological detection of neurons

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Nanotechnology and Precision Engineering 2024年第2期7卷 1-10页

作者： Yan Yang Shihong Xu Yu Deng yaoyao liu Kui Zhang Shiya Lv Longze Sha Qi Xu Xinxia Cai Jinping Luo State Key Laboratory of Transducer Technology Aerospace Information Research InstituteChinese Academy of SciencesBeijing 100190China School of Electronic Electrical and Communication EngineeringUniversity of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Medical Molecular Biology Institute of Basic Medical SciencesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100005China

To enable the detection and modulation of modularized neural networks in vitro,this study proposes a microfluidic microelectrode array chip for the cultivation,compartmentalization,and control of neural *** chip was designed based on the specific structure of neurons and the requirements for detection and ***-element analysis of the chip’s flow field was conducted using the COMSOL Multiphysics software,and the simulation results show that the liquid within the chip can flow smoothly,ensuring stable flow fields that facilitate the uniform growth of neurons within the microfluidic *** employing MEMS technology in combination with nanomaterial modification techniques,the microfluidic microelectrode array chip was fabricated *** hippocampal neurons were cultured on the chip,forming a well-defined neural *** electrical activity of the detected neurons was recorded,exhibiting a 23.7%increase in amplitude compared to neuronal discharges detected on an open-field microelectrode *** study provides a platform for the precise detection and modulation of patterned neuronal growth in vitro,potentially serving as a novel tool in neuroscience research.

关键词： Microfluidic Microelectrode array In vitro Neural chip

CNCC Toward Sustainable Future

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China News Release 2024年第6期 30-34页

作者： Yu Dongyun liu yaoyao Jia Longhuizi 不详

Children are the future and hope of *** growth and development are crucial for sustainable *** China National Children's Center(CNCC),established after China's reform and opening-up,is the first state-level research institution focused on children's *** serves as a hub for international exchanges and showcases China's efforts in child *** CNCC has been sticking to its mission to nurture talent for the Party and the country.

关键词： Sustainable development CNCC

Uncovering Small RNAs in Penicillium digitatum by Transcriptome Sequencing

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American Journal of Plant Sciences 2022年第7期13卷 1006-1022页

作者： Pengcheng Zhang Qinru Yu Ran Li yaoyao liu Tongfei Lai College of Life and Environmental Science Hangzhou Normal University Hangzhou China Worcester-Hangzhou Joint Molecular Plant Health Laboratory School of Science and the Environment University of Worcester Worcester UK

Small RNAs in Penicillium digitatum were identified and analyzed via transcriptome sequencing on the BGISEQ-500 platform. A total of 15 predicted miRNAs and 10718 novel siRNAs were found. Their length distribution, sequence, predicted construction, base bias, expression levels and potential targets were determined as well. Through pathway and KEGG enrichment analysis, the miRNA target genes were mostly involved in carbohydrate metabolism, transport and catabolism, translation and amino acid metabolism. The target genes involved in aflatoxin biosynthesis and proteasome had a higher rich factor value. The results will provide a theoretical foundation for understanding the developmental and pathogenic mechanisms of P. digitatum at the transcriptional level.

关键词： Penicillium digitatum Transcriptome Sequencing MicroRNA Small Interfering RNA

First Report of a Postharvest Fruit Rot on Apple Caused by <i>Diaporthe phaseolorum</i>var. <i>caulivora</i>in China: A Note

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American Journal of Plant Sciences 2020年第10期11卷 1612-1617页

作者： Yuanzhi Chen Quan Zhou Yangying Sun Ran Li yaoyao liu Ting Zhou College of Life and Environmental Science Hangzhou Normal University Hangzhou China

Brown rots of Red Fuji apples were observed in Hangzhou city (Zhengjiang Province, China). The causal agent was isolated and identified in both morphological and molecular genetic levels. The phenotype and phylogenetic analysis revealed that the isolate was Diaporthe phaseolorum var. caulivora, and its pathogenicity on apple fruit was confirmed by re-inoculation experiment. To our knowledge, this is the first report of D. phaseolorum var. caulivora causing postharvest fruit rot on apple in China.

关键词： Apple Postharvest Pathogen ITS-rDNA Diaporthe phaseolorum var. caulivora