Wireless closed-loop deep brain stimulation using microelectrode array probes
基于微电极阵列探针的无线闭环脑深部刺激技术作者机构：State Key Laboratory of Transducer TechnologyAerospace Information Research InstituteChinese Academy of SciencesBeijing 100190China School of ElectronicElectrical and Communication EngineeringUniversity of Chinese Academy of SciencesBeijing 100049China
出 版 物：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 (浙江大学学报（英文版）B辑（生物医学与生物技术）)
年 卷 期：2024年第25卷第10期
页 面：803-823页
核心收录：
基 金：supported by the National Natural Science Foundation of China(Nos.T2293730,T2293731,62121003,61960206012,61973292,62171434,61975206,and 61971400) the National Key Research and Development Program of China(Nos.2022YFC2402501 and 2022YFB3205602) the Major Program of Scientific and Technical Innovation 2030(No.2021ZD02016030) the Scientific Instrument Developing Project of the Chinese Academy of Sciences(No.GJJSTD20210004)
主 题：Deep brain stimulation(DBS) Wireless closed-loop deep brain stimulation(CL-DBS)microsystem Microelectrode array(MEA)probe Optical stimulation Electrical stimulation
摘 要：Deep brain stimulation(DBS),including optical stimulation and electrical stimulation,has been demonstrated considerable value in exploring pathological brain activity and developing treatments for neural *** in DBS microsystems based on implantable microelectrode array(MEA)probes have opened up new opportunities for closed-loop DBS(CL-DBS)in *** technology can be used to detect damaged brain circuits and test the therapeutic potential for modulating the output of these circuits in a variety of diseases *** the success and rapid utilization of MEA probe-based CL-DBS microsystems,key challenges,including excessive wired communication,need to be urgently *** this review,we considered recent advances in MEA probe-based wireless CL-DBS microsystems and outlined the major issues and promising prospects in this *** technology has the potential to offer novel therapeutic options for psychiatric disorders in the future.
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