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Wheat kinase TaSnRK2.4 forms a functional module with phosphatase TaPP2C01 and transcription factor TaABF2 to regulate drought response

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The Crop Journal 2024年第2期12卷 384-400页

作者： yanyang zhang Xiaoyang Hou Tianjiao Li Ziyi Wang Jiaqi zhang Chunlin zhang Xianchang Liu Xinxin Shi Wanrong Duan Kai Xiao State Key Laboratory of North China Crop Improvement and Regulation Baoding 071001HebeiChina College of Agronomy Hebei Agricultural UniversityBaoding 071001HebeiChina

SNF1-related protein kinase 2(SnRK2)family members are essential components of the plant abscisic acid(ABA)signaling pathway initiated by osmotic stress and triggering a drought stress *** study characterized the molecular properties of TaSnRK2.4 and its function in mediating adaptation to drought in Triticum *** of TaSnRK2.4 were upregulated upon drought and ABA signaling and associated with drought-and ABA-responsive cis-elements ABRE and DRE,and MYB and MYC binding sites in the promoter as indicated by reporter GUS protein staining and activity driven by truncations of the *** two-hybrid,BiFC,and Co-IP assays indicated that TaSnRK2.4 protein interacts with TaPP2C01 and an ABF transcription factor(TF)*** results suggested that TaSnRK2.4 forms a functional TaPP2C01-TaSnRK2.4-TaABF2 module with its upstream and downstream *** analysis revealed that TaSnRK2.4 and TaABF2 positively regulate drought tolerance whereas TaPP2C01 acts negatively by modulating stomatal movement,osmotic adjustment,reactive oxygen species(ROS)homeostasis,and root *** analysis,yeast one-hybrid,and transcriptional activation assays indicated that several osmotic stress-responsive genes,including TaSLAC1-4,TaP5CS3,TaSOD5,TaCAT1,and TaPIN4,are regulated by *** analysis verified their functions in positively regulating stomatal movement(TaSLAC1-4),proline accumulation(TaP5CS3),SOD activity(TaSOD5),CAT activity(TaCAT1),and root morphology(TaPIN4).There were high correlations between plant biomass and yield with module transcripts in a wheat variety panel cultivated under drought conditions in the *** findings provide insights into understanding plant drought response underlying the SnRK2 signaling pathway in common wheat.

关键词： Triticum aestivum SnRK2.4 kinase Gene expression Protein interaction Transgene analysis Transcriptional activation

Experimental Study on Convective Heat Transfer in Tube-Side of Water Jacket-Tube Heat Exchanger by Electrohydrodynamics Effect

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Wuhan University Journal of Natural Sciences 2011年第1期16卷 49-54页

作者： YANG Xia zhang Jie WU yanyang zhang Tao MAO Zhihui School of Mechanical and Electrical Engineering WuhanInstitute of Technology Wuhan 430073 Hubei China

The electrohydrodynamics （EHD） enhancement of convection heat transfer of water in a jacket tube heat exchanger was studied through an experimental method in this paper. In the experiment,a DC high voltage electrode was set in the central tube-side of the heat exchanger,and the high voltage electrode in the tube-side was adjustable in the range of 0-40 kV. Five differ-ent combinations of heat transfer enhancement experiments were conducted under the different voltage and rate of flow. The results indicate that the maximal enhancement coefficient θ is 1.224 when the flow rate of tube-side inlet is 0.1 m3/h. It is proved that,for the work medium of water,the convective heat transfer can be enhanced by applying high electric field. The performance of EHD-enhanced is sensitive to the variation of flow rate,and in the same flow rate,there exist an optimized voltage in the EHD-enhanced process ra-ther than the monotonic positive-correlation relationship.

关键词： electrohydrodynamics (EHD) heat transfer enhance-ment water jacket-tube heat exchanger convection heat transfer

Interplay of transcription factors and microRNAs during embryonic hematopoiesis

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Science China(Life Sciences) 2017年第2期60卷 168-177页

作者： Xueping Gong Ruihua Chao Pengxiang Wang Xiaoli Huang Jingjing zhang Xiaozhou Zhu yanyang zhang Xue Yang Chao Hou Xiangjun Ji Tieliu Shi Yuan Wang Shanghai Key Laboratory of Regulatory Biology Institute of Biomedical Sciences and School of Life Sciences East China Normal University Shanghai 200241 China

Hematopoietic stem cells (HSCs), which are localized in the bone marrow of adult mammals, come from hematopoietic endothelium during embryonic stages. Although the basic processes of HSC generation and differentiation have been described in the past, the epigenetic regulation of embryonic hematopoiesis remains to be fully described. Here, by utilizing an in vitro differentiation system of mouse embryonic stem cells (ESCs), we identified more than 20 microRNAs that were highly enriched in embryonic hematopoietic cells, including some (e.g. miR-10b, miR-15b, and miR-27a) with previously unknown functions in blood formation. Luciferase and gene expression assays further revealed combinational binding and regulation of these microRNAs by key transcription factors in blood cells. Finally, bioinformatics and functional analyses supported an interactive regulatory control between transcription factors and microRNAs in hematopoiesis.

关键词： hematopoiesis embryonic stem cells microRNA

Formable porous biochar loaded with La-Fe(hydr)oxides/montmorillonite for efficient removal of phosphorus in wastewater:process and mechanisms

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Biochar 2022年第1期4卷 296-314页

作者： Enhui Sun yanyang zhang Qingbo Xiao Huayong Li Ping Qu Cheng Yong Bingyu Wang Yanfang Feng Hongying Huang Linzhang Yang Charles Hunter Key Laboratory of Saline-Alkali Soil Improvement and Utilization(Coastal Saline-Alkali Lands) Ministry of Agriculture and Rural AffairsJiangsu Collaborative Innovation Center for Solid Organic Waste Resource UtilizationInstitute of Agricultural Resources and EnvironmentJiangsu Academy of Agricultural SciencesNanjing 210014China School of Life Sciences College of AgricultureEngineering and ScienceUniversity of KwaZulu-Natal(Pietermaritzburg Campus)Private Bag X01Scottsville 3209Republic of South Africa State Key Laboratory of Pollution Control and Resource Reuse School of the EnvironmentNanjing UniversityNanjing 210023China Institute of Germplasm Resources and Biotechnology Jiangsu Academy of Agricultural SciencesNanjing 210014China Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse School of Environmental and Biological EngineeringNanjing University of Science and TechnologyNanjing 210094China

The development of biochar-based granule-like adsorbents suitable for scaled-up application has been attracting increasing attention in the field of water ***,a new formable porous granulated biochar loaded with La-Fe(hydr)oxides/montmorillonite(LaFe/MB)was fabricated via a granulation and pyrolysis process for enhanced phosphorus(P)removal from *** acted as a binder that increased the size of the granulated biochar,while the use of Fe promoted the surface charge and facilitated the dispersion of La,which was responsible for selective phosphate ***/MB exhibited rapid phosphate adsorption kinetics and a high maximum adsorption capacity(Langmuir model,52.12 mg P g^(−1)),which were better than those of many existing granulated *** desorption and recyclability experiments showed that LaFe/MB could be regenerated,and maintained 76.7%of its initial phosphate adsorption capacity after four adsorption *** high hydraulic endurance strength retention rate of the developed material(91.6%)suggested high practical applicability in actual ***-static attraction,surface precipitation,and inner-sphere complexation via ligand exchange were found to be involved in selective P removal over a wide pH range of *** thermodynamic parameters were determined,which revealed the feasibility and spontaneity of *** on approximate site energy distribution analyses,high distribution frequency contributed to efficient P *** research results provide a new insight that LaFe/MB shows great application prospects for advanced phosphate removal from wastewater.

关键词： Formable porous biochar Montmorillonite Metal(hydr)oxide Wastewater phosphate removal Adsorption mechanism

接续、强化与辟新:全面从严治党的政治发展维度

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Epidemiological survey and genetic characterization of type 3 vaccine-derived poliovirus isolated from a patient with four doses of inactivated polio vaccine in Henan Province,China

山西大学学报（哲学社会科学版） 2024年第3期47卷 144-151页

作者：张岩阳山西大学政治与公共管理学院山西太原 030006

权力如何生成权威是政治生活的核心议题.在政治发展的视野内,权力生成权威有两条路径,分别是强调约束权力的规范路径和着眼权力绩效的效率路径.规范路径生成意识形态型与法理型两类权威,效率路径则衍生出绩效型权威.现代政治权威是由意... 详细信息

权力如何生成权威是政治生活的核心议题.在政治发展的视野内,权力生成权威有两条路径,分别是强调约束权力的规范路径和着眼权力绩效的效率路径.规范路径生成意识形态型与法理型两类权威,效率路径则衍生出绩效型权威.现代政治权威是由意识形态型、绩效型以及法理型三类权威组成的复合体,其如何塑造是现代政治的主要任务.在百年政治发展历程中,中国共产党经历了从意识形态型权威到绩效型权威再到构建多元复合型权威的演变脉络.党的十八大后启动的全面从严治党以多种方式持续推动三类权威的强化和整合,一个不同于西式政治权威的、一体三元式结构的权威复合体轮廓逐渐清晰,由此构成中国式现代化政治板块的核心要件.

关键词：全面从严治党政治发展权力权威

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Infectious Diseases of Poverty 2022年第6期11卷 99-100页

作者： Mingyu zhang Jianhui Yang Yiran Bai Hui Zhu Changshuang Wang Lu zhang Jin Xu Mingxia Lu Xiaoxiao zhang Zhanpei Xiao Yating Ma Yan Wang Xiaolei Li Dongyan Wang Shuangli Zhu Dongmei Yan Wenbo Xu Yong zhang yanyang zhang Henan Center for Disease Control and Prevention ZhengzhouHenanPeople’s Republic of China WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory for Biosafety National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingPeople’s Republic of China

Background:Vaccine-derived poliovirus(VDPV)is a potential threat to polio eradication because they can reintroduce into the general population and cause paralytic polio outbreaks,a phenomenon that has recently emerged as a prominent public health concern at the end of global polio *** study aimed to describe the epidemiology and genetic characteristics of the frst VDPV identifed from a patient with acute faccid paralysis(AFP),with four doses of inactivated polio vaccine immunization in Henan Province,China in ***:The patient was diagnosed with type 3 ***,a series of epidemiological approaches was implemented,including a retrospective search of AFP cases,rate of vaccination assessment,study of contacts,and supplementary immunization *** samples were collected,viral isolation was performed,and the viral isolates were characterized using full-length genomic sequencing and bioinformatic ***:Phylogenetic analysis showed that the viral isolates from the patient were diferent from other reported genetic clusters of type 3 VDPV *** were identifed as a Sabin 3/Sabin 1 recombinant VDPV with a crossover site in the P2 *** substitutions,including U→C(472)and C→U(2493),have been identifed,both of which are frequently observed as reversion mutations in neurovirulent type 3 poliovirus.A unique aspect of this case is that the patient had been vaccinated with four doses of inactive polio vaccine,and the serum neutralizing antibody for Sabin types 1 and 3 were 1∶16 and 1∶512,***,the patient was speculated to have been infected with type 3 VDPV,and the virus continued to replicate and be excreted for at least 41 ***:The existence of this kind of virus in human population is a serious risk and poses a severe challenge in maintaining a polio-free status in *** the best of our knowledge,this is the frst report of VDPV identifed in the Henan province of *** results hig

关键词： Epidemiological Survey Genetic characterization Type 3 vaccine-derived poliovirus Recombination Henan China

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浅谈金融危机下中国出版业的对策

出版发行研究 2009年第11期 23-26页

作者：张延扬金盾出版社

由美国金融危机引发的全球性经济危机,其强度可以比得上1929年世界经济大萧条。在国际国内严峻经济形势面前,准确了解金融危机对国际尤其是国内出版业的影响,把握出版业在金融危机面前蕴含的潜在机遇,探讨如何促进国内出版产业健康发展... 详细信息

由美国金融危机引发的全球性经济危机,其强度可以比得上1929年世界经济大萧条。在国际国内严峻经济形势面前,准确了解金融危机对国际尤其是国内出版业的影响,把握出版业在金融危机面前蕴含的潜在机遇,探讨如何促进国内出版产业健康发展,是中国出版行业当前应着重关注的课题。本文即在此形势下,分析探讨了我国出版业应对危机,保持健康发展的基本思路和方法。

关键词：金融危机出版业发展

Effectiveness of Inactivated COVID-19 Vaccines Against Symptomatic,Pneumonia,and Severe Disease Caused by the Delta Variant:Real World Study and Evidence—China,2021

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China CDC weekly 2022年第4期4卷 57-65页

作者： Dan Wu yanyang zhang Lin Tang Fuzhen Wang Ying Ye Chao Ma Hui Zheng Wenzhou Yu Lei Cao Yifan Song Abuduwaili Reyimu Xiaoxiao zhang Haifeng Wang Yifei Nie Mingxia Lu Muge Qi Jun Li Ruolin Wang Kaichao Yang Changshuang Wang Lawrence Everett Rodewald Geroge Fu Gao Zhijie An Zundong Yin Chinese Center for Disease Control and Prevention BeijingChina Henan Provincial Disease Control and Prevention ZhengzhouHenanChina Akesu Prefectural Center for Disease Control and Prevention AkesuXinjiang Uygur Autonomous RegionChina China Field Epidemiology Training Program Chinese Center for Disease Control and PreventionBeijingChina

Summary What is already known about this topic?Effectiveness of China’s 2 inactivated vaccines(BBIBPCorV and CoronaVac)against pre-Delta severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)variants ranged from 47%to over 90%,depending on the clinical endpoint,and with greater effectiveness against more severe coronavirus disease 2019(COVID-19).During an outbreak in Guangdong,inactivated vaccine effectiveness(VE)against the Delta variant was 70%for symptomatic infection and 100%for severe ***,separate or combined VE estimates for the two inactivated vaccines against Delta are not *** is added by this report?In an outbreak that started in a hospital,VEs of completed primary vaccination with inactivated COVID-19 vaccines against symptomatic COVID-19,COVID-19 pneumonia,and severe COVID-19 caused by the Delta variant were 51%,61%,and 82%.Completed primary vaccination reduced the risk of progressing from mild to moderate or severe COVID-19 by 74%.VE estimates for BBIBP-CorV and CoronaVac or combined vaccination were similar,and partial vaccination was *** are the implications for public health practice?Completed primary vaccination with either of the 2 inactivated COVID-19 vaccines reduces risk of symptomatic COVID-19,COVID-19 pneumonia,and severe COVID-19 caused by the Delta *** of the completed primary vaccination with two doses is necessary for protection from Delta.

关键词： vaccination doses vaccine

特大城市制造业发展测算与疏解思路——以北京为例

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经济与管理研究 2016年第7期37卷 103-111页

作者：张杰徐艳阳张玉春首都经济贸易大学城市经济与公共管理学院北京市经济和信息化委员会经济运行处首都经济贸易大学统计学院

世界大都市,尤其是特大城市的制造业发展和疏解程度,对于城市经济增长和产业发展意义重大,对于中国特大城市的发展也具有重要借鉴价值。本文进行制造业发展国际比较研究,并择取北京作为数据分析和观察对象。京津冀协同发展上升为国家重... 详细信息

世界大都市,尤其是特大城市的制造业发展和疏解程度,对于城市经济增长和产业发展意义重大,对于中国特大城市的发展也具有重要借鉴价值。本文进行制造业发展国际比较研究,并择取北京作为数据分析和观察对象。京津冀协同发展上升为国家重大战略决策,这一决策的核心任务即是有序疏解北京非首都功能,其中北京工业的疏解和提升发展对于北京构建高精尖经济结构和提升核心竞争力具有重要作用。本文在文献综述和世界大都市制造业转型提升经验借鉴的基础上,针对首都功能疏解,分类测算了2013年北京市规模以上制造业行业中类发展情况,进行了中类行业分类指标相关性分析和权重系数测算,并最终提出了北京市制造业疏解思路与提升路径的政策建议。

关键词：北京制造业功能疏解中类行业测算提升路径