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TD-AltBOC:A new COMPASS B2 modulation

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Science China(Physics,Mechanics & Astronomy) 2011年第6期54卷 1014-1021页

作者： TANG ZuPing zhou HongWei WEI JiaoLong YAN Tao LIU YuQi RAN YiHang zhou yanling Department of Electronics and Information Engineering Huazhong University of Science and TechnologyWuhan 430074China Beijing Institute of Tracking and Telecommunication Technology Beijing 100094China

AltBOC(15,10) is the baseline of COMPASS B2 signal *** is a BOC-like signal having different PN codes in the lower and the upper main split lobes,which allow one signal service per *** two lobes can be received and processed separately like two BPSK(10) signals,or coherently processed to achieve better *** among COMPASS B2,Galileo E5 and GPS L5 is also achievable using AltBOC ***,Galileo's 4-code AltBOC has drawbacks such as low efficiency and great receiver *** paper presents a new modulation type named TD-AltBOC (Time Division AltBOC).The signal generation scheme and receiving method are presented,and are compared with AltBOC in the areas of power spectrum,ranging accuracy,anti-multipath performance,anti-interference performance,processing flexibility and *** results show TD-AltBOC has similar spectrum characteristics,interoperability,flexibility and anti-interference performance with *** the frontend bandwidth is more than 50 MHz,TD-AltBOC can achieve better ranging accuracy and anti-multipath *** also has such advantages as high efficiency and low receiver ***-AltBOC could be a good solution to COMPASS B2 navigation signal.

关键词： GNSS COMPASS signal structure TD-AltBOC signal modulation

Diffusion tensor imaging study of fractional anisotropy values and the area of both cerebral peduncles in healthy adults

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Neural Regeneration Research 2011年第10期6卷 797-800页

作者： Zhibin Song Suyue Pan yanling zhou Yanjiang Dong Haimao Liang Zhengfeng Zhu Department of Neurology Xiaolan Hospital of Southern Medical University Zhongshan 528415 Guangdong Province China Department of Neurology Nanfang Hospital of Southern Medical University Guangzhou 510515 Guangdong Province China

Diffusion tensor imaging was performed in 105 volunteers free of central nervous system *** differences were found in fractional anisotropy between the left and right cerebral peduncles among subjects（P 0.05）.The lower limit value of fractional anisotropy was 0.36,and the asymmetry ratio was *** area and lower limit value of the cerebral peduncles were 0.90 cm2 and 0.83,*** results will be useful in evaluating the diagnosis of Wallerian degeneration following cerebral infarction.

关键词： healthy Chinese people cerebral peduncle fractional anisotropy area diffusion tensor imaging

3D printed titanium scaffolds with ordered TiO2 nanotubular surface and mesoporous bioactive glass for bone repair

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Progress in Natural Science:Materials International 2020年第4期30卷 502-509页

作者： Pengyu Zhao Yaqin Liu Tian Li yanling zhou Sander Leeflang Lei Chen Chengtie Wu Jie zhou Zhiguang Huan State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences Department of Biomechanical Engineering Delft University of Technology

Titanium alloy scaffolds have recently gained substantial interest for the treatment of critical-size bone defect,particularly along with the maturity of the 3D printing technology that is capable of turning scaffold design ideas into real implants. As titanium alloys lack surface osteogenic activity, for improved biological performance of such scaffolds, surface modification is necessary. Various coating materials and coating methods have been explored. In this study, we developed a unique surface modification method to provide the surface of 3D printed titanium scaffolds with nano-sized structure and bioactive agent. Uniform, ordered TiO2nanotube arrays were formed by applying two-step anodization, and then mesoporous bioactive glass（MBG） was loaded into nanotubes. The results of in vitro immersion testing showed that bioactive ions, i.e., Si and Ca ions, could be steadily and continuously released from MBG into basal medium. The assessment of the responses of h BMSCs confirmed that the surface-modified scaffolds supported the adhesion and proliferation of h BMSCs, indicating good surface cytocompatibility. The developed method of combining surface nanostructure and bioactive agent could be used as a new strategy to improve the osteogenic activity of 3D printed titanium alloy scaffolds.

关键词： Titanium Scaffold Mesoporous bioactive glass Nanotube Anodization

Why do stroke patients with negative motor evoked potential show poor limb motor function recovery?

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Neural Regeneration Research 2013年第29期8卷 2713-2724页

作者： Zhibin Song Lijuan Dang yanling zhou Yanjiang Dong Haimao Liang Zhengfeng Zhu Suyue Pan Department of Neurology Xiaolan Hospital of Southern Medical University Department of Neurology Nanfang Hospital of Southern Medical University

Negative motor evoked potentials after cerebral infarction, indicative of poor recovery of limb motor function, tend to be accompanied by changes in fractional anisotropy values and the cerebral pe-duncle area on the affected side, but the characteristics of these changes have not been reported. This study included 57 cases of cerebral infarction whose motor evoked potentials were tested in the 24 hours after the first inspection for diffusion tensor imaging, in which 29 cases were in the negative group and 28 cases in the positive group. Twenty-nine patients with negative motor evoked potentials were divided into two groups according to fractional anisotropy on the affected side of the cerebral peduncle： a fractional anisotropy 〈 0.36 group and a fractional anisotropy 〉 0.36 group. All patients underwent a regular magnetic resonance imaging and a diffusion tensor imaging examina- tion at 1 week, 1, 3, 6 and 12 months after cerebral infarction. The FugI-Meyer scores of their hemiplegic limbs were tested before the magnetic resonance and diffusion tensor imaging exami-nations. In the negative motor evoked potential group, fractional anisotropy in the affected cerebral peduncle declined progressively, which was most obvious in the first 1-3 months after the onset of cerebral infarction. The areas and area asymmetries of the cerebral peduncle on the affected side were significantly decreased at 6 and 12 months after onset. At 12 months after onset, the area asymmetries of the cerebral peduncle on the affected side were lower than the normal lower limit value of 0.83. FugI-Meyer scores in the fractional anisotropy ≥0.36 group were significantly higher than in the fractional anisotropy 〈 0.36 group at 3-12 months after onset. The fractional anisotropy of the cerebral peduncle in the positive motor evoked potential group decreased in the first 1 month after onset, and stayed unchanged from 3-12 months; there was no change in the area of the cerebral peduncle in the first

关键词： neural regeneration neuroimaging cerebral infarction motor evoked potential fractional anisotropy cerebralpeduncle magnetic resonance diffusion tensor imaging grants-supported paper neuroregeneration

Magnesium-based biomaterials for coordinated tissue repair:A comprehensive overview of design strategies,advantages,and challenges

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Journal of Magnesium and Alloys 2024年第8期12卷 3025-3061页

作者： Yuan Chen Siming Zhang Jiaxiang Bai Yao Yang Yingjie Wang yanling zhou Wei Jiang Junjie Wang Junchen Zhu Chen Zhu Xianzuo Zhang Department of Orthopedics Centre for Leading Medicine and Advanced Technologies of IHMThe First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui230022China Department of Orthopedics The Second Affiliated Hospital of Anhui University of Chinese MedicineHefei 230001China National Center for Translational Medicine(Shanghai)SHU Branch Shanghai UniversityShanghaiChina Department of Orthopedics The First Affiliated Hospital of Anhui Medical UniversityHefei 230001China

Magnesium-based biomaterials(MBMs)are one of the most promising materials for tissue engineering due to their unique mechanical properties and excellent functional *** review describes the development,advantages,and challenges of MBMs for biomedical applications,especially for tissue repair and *** history of the use of MBMs from the beginning of the 20th century is traced,and the transformative advances in contemporary applications of MBMs in areas such as orthopedics and cardiovascular surgery are *** review also provides insight into the signaling pathways affected by MBMs,such as the PI3K/Akt and RANKL/RANK/OPG pathways,which are critical for osteogenesis and *** review advocates that future research should focus on optimizing alloy compositions,surface modification and exploring innovative technologies such as 3D printing to improve the efficacy of MBMs in complex tissue *** potential of MBMs to tissue engineering and regenerative medicine is significant,urging further exploration and interdisciplinary collaboration to maximize their therapeutic effects.

关键词： Magnesium-based biomaterials Design strategies Functional properties Clinical applications Challenges

3D printing of conch-like scaffolds for guiding cell migration and directional bone growth

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Bioactive Materials 2023年第4期22卷 127-140页

作者： Boshi Feng Meng Zhang Chen Qin Dong Zhai Yufeng Wang yanling zhou Jiang Chang Yufang Zhu Chengtie Wu State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai200050People’s Republic of China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing100049People’s Republic of China

Regeneration of severe bone defects remains an enormous challenge in *** regenerative scaffolds to directionally guide bone growth is a potential strategy to overcome this ***,an interesting creature widely spreading in ocean,has tough spiral shell that can continuously grow along the spiral ***,inspired by the physiological features of conches,a conch-like(CL)scaffold based onβ-TCP bioceramic material was successfully prepared for guiding directional bone growth via digital light processing(DLP)-based 3D *** from the spiral structure,the CL scaffolds significantly improved cell adhesion,proliferation and osteogenic differentiation in vitro compared to the conventional 3D ***,the spiral structure in the scaffolds could efficiently induce cells to migrate from the bottom to the top of the scaffolds,which was like“cells climbing stairs”.Furthermore,the capability of guiding directional bone growth for the CL scaffolds was demonstrated by a special half-embedded femoral defects model in *** new bone tissue could consecutively grow into the protruded part of the scaffolds along the spiral *** work provides a promising strategy to construct biomimetic biomaterials for guiding directional bone tissue growth,which offers a new treatment concept for severe bone defects,and even limb regeneration.

关键词： 3D printing Spiral structure Conch-like scaffolds Cell migration Tissue regeneration Severe bone defects

Effect of Cognitive Behavioral Intervention on Plasma Cortisol in Patients with Breast Cancer PTSD

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Journal of Cancer Therapy 2024年第3期15卷 62-70页

作者： yanling zhou Min Guo President Office The Fourth People’s Hospital of Haikou City Haikou China

Objective: To investigate the effect of cognitive behavioral intervention on plasma cortisol in patients with breast cancer PTSD before surgery. Methods: SCL-90, EPQ-N and cognitive behavior intervention were performed on 30 patients with PTSD, 30 patients without PTSD and 30 normal subjects, and their fasting blood was collected to analyze cortisol in the morning. Results: The scores of SCL-90 and EPQ-N in patients with breast cancer PTSD were significantly higher than those in non-PTSD patients and normal subjects (P < 0.01). After cognitive behavioral intervention, the plasma cortisol level of breast cancer PTSD patients was significantly decreased (P Conclusion: Compared with non-PTSD breast cancer patients and normal control group, breast cancer PTSD patients had more serious psychological problems, worse emotional stability and higher plasma cortisol level. Cognitive-behavioral intervention can effectively reduce plasma cortisol levels in breast cancer patients with PTSD.

关键词： Cognitive Behavior Intervention Breast Cancer PTSD Cortisol

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Biomedical Materials

Bulletin of the Chinese Academy of Sciences 2011年第1期25卷 42-43页

作者： CHANG Jiang zhou yanling Biomaterials and Tissue Engineering Research Center Shanghai Institute of CeramicsChinese Academy of Sciences Shanghai 200050

Biomedical materials, biomaterials for short, is regarded as "any substance or combination of substances, synthetic or natural in origin, which can be used for any period of time, as a whole or as part of a system which treats, augments, or replaces any tissue, organ or function of the body" (Vonrecum & Laberge, 1995).Biomaterials can save lives, relieve suffering and enhance the quality of life for human being.

关键词：生物医学材料生物材料物质

Distinguishing the Effects of Cryosphere Change in the Background of Climate Change in China

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Research in Cold and Arid Regions 2010年第1期2卷 87-92页

作者： LiHua zhou yanling Zhu XiKe Sun Key Laboratory of Desert and Desertification CoM and Arid Regions Environmental and Engineering Research Institute Chinese Academy of Sciences Lanzhou Gansu 730000 China

Climate change has major impacts directly on the natural ecosystem and human society, of which the cryosphere is most easily affected be-cause of its frangibility and sensitivity. Similarly, cryosphere change has numerous impacts on the natural ecosystem and human society, which may resemble an indirect influence of climate change. These two types of impacts, in shared fields, are distinguished in space and time by effective mechanisms and processes. Climate change has positive and negative impacts on some systems, which may be adjusted by cryosphere change. These indirect and direct impacts may be distinguished, and then correct policies and measures can be made against these changes.

关键词： cryosphere change climate change indirect impact direct impact distinguish