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Evolutionary mechanisms and practical significance of reproductive success and clonal diversity in unisexual vertebrate polyploids

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Science China(Life Sciences) 2024年第3期67卷 449-459页

作者： Meng Lu Li zhou Jian-Fang gui State Key Laboratory of Freshwater Ecology and Biotechnology Hubei Hongshan Laboratorythe Innovation Academy of Seed DesignInstitute of HydrobiologyChinese Academy of SciencesWuhan 430072China University of Chinese Academy of Sciences Beijing 100049China

Unisexual reproduction is generally relevant to polyploidy, and unisexual vertebrates are often considered an evolutionary “dead end” due to the accumulation of deleterious mutations and absence of genetic diversity. However, some unisexual polyploids have developed strategies to avoid genomic decay, and thus provide ideal models to unveil unexplored evolutionary mechanisms, from the reproductive success to clonal diversity creation. This article reviews the evolutionary mechanisms for overcoming meiotic barrier and generating genetic diversity in unisexual vertebrates, and summarizes recent research advancements in the polyploid Carassius complex. Gynogenetic gibel carp(Carassius gibelio) is a unique amphitriploid that has undergone a recurrent autotriploidy and has overcome the bottleneck of triploid sterility via gynogenesis. Recently, an efficient strategy in which ploidy changes, including from amphitriploid to amphitetraploid, then from amphitetraploid to novel amphitriploid, drive unisexual-sexual-unisexual reproduction transition and clonal diversity has been *** on this new discovery, multigenomic reconstruction biotechnology has been used to breed a novel strain with superior growth and stronger disease resistance. Moreover, a unique reproduction mode that combines both abilities of ameiotic oogenesis and sperm-egg fusion,termed as ameio-fusiongensis, has been discovered, and it provides an efficient approach to synthesize sterile allopolyploids. In order to avoid ecological risks upon escape and protect the sustainable property rights of the aquaculture seed industry, a controllable fertility biotechnology approach for precise breeding is being developed by integrating sterile allopolyploid synthesis and gene-editing *** review provides novel insights into the origin and evolution of unisexual vertebrates and into the attempts being made to exploit new breeding biotechnologies in aquaculture.

关键词： unisexual vertebrates polyploidy reproduction transition clonal diversity precise breeding genomic reconstruction controllable fertility

Simulation of urban expansion using geographical similarity transition rules and neighbourhood sizes

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Journal of Geographical Sciences 2024年第7期34卷 1394-1414页

作者： LI Yinqi AN yue zhou zhou REN Hui TAN Xuelan College of Resources Hunan Agricultural UniversityChangsha410128China College of Geographical Sciences Hunan Normal UniversityChangsha410081China

Most existing cellular automata(CA)models impose strict requirements on the number and spatial distribution of *** makes it a challenge to capture spatial heterogeneity in urban dynamics and meet the modeling needs of large and complex geographic *** paper presents a CA model based on geographically optimal similarity(GOS)transition rules and similarly sized neighborhoods(SSN).By comparing the similarity in geographical configuration between samples and predicted points,the model enables a comprehensive characterization of the driving mechanism behind urban expansion and its self-organizing *** helps to mitigate the impact of sample selection and assumptions about spatial stationarity on simulation *** performance of GOS-SSN-CA simulation was tested by taking the urban expansion in the Changsha-Zhuzhou-Xiangtan urban agglomeration in China as an *** results show that GOS can derive more accurate and reliable urban transition rules with fewer samples,thereby significantly reducing spatial prediction errors compared with logistic ***,SSN selects different neighborhood sizes to represent the difference between the local self-organizing range and surrounding cells,thus further improving the simulation accuracy and restricting urban expansion ***,GOS-SSN-CA effectively characterizes the geographical similarity of urban expansion,improves simulation accuracy while constraining the urban expansion form,and enhances the practical application value of CA.

关键词： urban growth cellular automata geographic similarity model optimization spatial nonstationarity

Self-powered and self-sensing devices based on piezoelectric energy harvesting

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Science China(Technological Sciences) 2024年第6期67卷 1631-1667页

作者： CHEN GanTong ZHU yue HUANG DongMei zhou ShengXi School of Aeronautics Northwestern Polytechnical UniversityXi’an710072China School of Mathematics and Statistics Xidian UniversityXi’an710071China

Wearable devices,interactive human-machine interface equipment,wireless sensors,and small-scale cleaning devices play crucial roles in biomedical implantation,disease treatment,health monitoring,environmental purification,*** devices require a sustainable energy source to work *** the consideration of the global energy crisis and environmental pollution,researchers are exploring new,stable,and environmentally friendly methods to power these low-powered *** energy is one of the most abundant natural energy *** mechanical energy from the ambient environment or host structures into electrical energy via the direct piezoelectric effect is an efficient energy harvesting *** paper reviews the application of advanced piezoelectric materials,and small-scale self-powered and self-sensing piezoelectric devices at the cubic centimeter scale in energy harvesting and health monitoring of human,animal,machinery,roads,bridges,as well as the pollutant degradation of the *** of these devices have the capability to not only harvest mechanical energy but also enable real-time monitoring and analysis of the electrical signals generated by the direct piezoelectric effect,facilitating prompt decision-making and appropriate *** addition,potential challenges and future prospects of small-scale self-powered and self-sensing piezoelectric devices are discussed.

关键词： piezoelectric energy harvesting self-powered self-sensing wearable devices implantable devices

Simulation of roof snow loads based on a multi-layer snowmelt model:Impact of building heat transfer

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Building Simulation 2024年第6期17卷 907-932页

作者： Xuanyi zhou Heng Chen yue Wu Tiange Zhang State Key Laboratory of Disaster Reduction in Civil Engineering Tongji UniversityShanghai200092China

To investigate the impact of building heat transfer on roof snow loads,roof snow loads and snow load thermal coefficients from 61 Chinese sites over a period of 50 years are simulated based on basic meteorological data such as temperature,humidity,wind speed,and precipitation,and a multi-layer snowmelt model considering the building heat ***,the accuracy of the multi-layer snowmelt model is validated using the data of observed ground snow load and roof snow melting *** relationship between meteorological conditions,snow cover characteristics,and thermal coefficients of snow loads in three representative sites is then ***,the characteristics of thermal coefficients in each zone are analyzed by combining them with the statistical results of meteorological data from 1960 to 2010,and the equations of thermal coefficients in different zones on indoor temperatures and roof heat transfer coefficients are fitted ***,the equations in this paper are compared with the thermal coefficients in the main snow load *** results indicate that the snowmelt model using basic meteorological data can effectively provide samples of roof snow *** the cold zone where the snow cover lasts for a long time and does not melt easily,the thermal coefficients of the snow loads on the heating buildings are lower than those in the warm zone due to the long-term influence of the heat from inside the *** coefficients are negatively correlated with indoor temperatures and roof heat transfer *** the indoor temperature is too low or the roof insulation is good,the roof snow load may exceed the ground snow *** thermal coefficients for heated buildings in the main snow load codes are more conservative than those calculated in this paper,and the thermal coefficients for buildings with lower indoor temperatures tend to be smaller.

关键词： snowmelt model roof snow load building heat transfer thermal coefficient load code

Historical Changes and Multi-scenario Prediction of Land Use and Terrestrial Ecosystem Carbon Storage in China

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Chinese Geographical Science 2024年第3期34卷 487-503页

作者： AN yue TAN Xuelan REN Hui LI Yinqi zhou zhou College of Resources Hunan Agricultural UniversityChangsha 410128China School of Geographic Science Hunan Normal UniversityChangsha 410081China

Terrestrial carbon storage(CS)plays a crucial role in achieving carbon balance and mitigating global climate *** study employs the Shared Socioeconomic Pathways and Representative Concentration Pathways(SSPs-RCPs)published by the Intergovernmental Panel on Climate Change(IPCC)and incorporates the Policy Control Scenario(PCS)regulated by China’s land management *** Future Land Use Simulation(FLUS)model is employed to generate a 1 km resolution land use/cover change(LUCC)dataset for China in 2030 and *** on the carbon density dataset of China’s terrestrial ecosystems,the study analyses CS changes and their relationship with land use changes spanning from 1990 to *** findings indicate that the quantitative changes in land use in China from 1990 to 2020 are characterised by a reduction in the area proportion of cropland and grassland,along with an increase in the impervious surface and forest *** changing trend is projected to continue under the PCS from 2020 to *** the SSPs-RCPs scenario,the proportion of cropland and impervious surface predominantly increases,while the proportions of forest and grassland continuously *** loss in China’s carbon storage from 1990 to 2020 amounted to 0.53×10^(12)kg,primarily due to the reduced area of cropland and *** the SSPs-RCPs scenario,more significant carbon loss occurs,reaching a peak of8.07×10^(12)kg in the SSP4-RCP3.4 *** loss is mainly concentrated in the southeastern coastal area and the Beijing-TianjinHebei(BTH)region of China,with urbanisation and deforestation identified as the primary *** the future,it is advisable to enhance the protection of forests and grassland while stabilising cropland areas and improving the intensity of urban *** research findings offer valuable data support for China’s land management policy,land space optimisation,and the achievement of dual-carbon targets.

关键词： land use change Future Land Use Simulation(FLUS)model carbon storage carbon density dataset land use scenario China

Decadal Changes in Dry and Wet Heatwaves in Eastern China:Spatial Patterns and Risk Assessment

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Advances in Atmospheric Sciences 2024年第10期41卷 2011-2026页

作者： yue ZHANG Wen zhou Ruhua ZHANG Department of Atmospheric and Oceanic Sciences and Institute of Atmospheric Sciences Fudan UniversityShanghai 200438China CMA-FDU Joint Laboratory of Marine Meteorology Fudan UniversityShanghai 200438China Key Laboratory of Polar Atmosphere-ocean-ice System for Weather and Climate Ministry of EducationFudan UniversityShanghai 200438China

Under global warming,understanding the long-term variation in different types of heatwaves is vital for China’s preparedness against escalating heat *** study investigates dry and wet heatwave shifts in eastern China over recent *** trend analysis displays pronounced warming in inland midlatitudes and the Yangtze River Valley,with increased humidity in coastal *** results indicate intensifying dry heatwaves in northern China,while the Yangtze River Valley sees more frequent dry *** the other hand,Indochina and regions north of 25°N also experience intensified wet heatwaves,corresponding to regional humidity *** analysis is conducted based on different situations:strong,frequent dry or wet *** dry heatwaves are influenced by anticyclonic circulations over northern China,accompanied by warming SST anomalies around the coastal midlatitudes of the western North Pacific(WNP).Frequent dry heatwaves are related to strong subsidence along with a strengthened subtropical high over the *** and frequent wet heatwaves show an intensified Okhotsk high at higher latitudes in the lower troposphere,and a negative circumglobal teleconnection wave train pattern in the upper *** El Niño SST patterns are observed in two kinds of wet heatwave and frequent dry heatwave *** analysis indicates that El Niño events heighten the likelihood of these heatwaves in regions most at *** global warming continues,adapting and implementing mitigation strategies toward extreme heatwaves becomes crucial,especially for the aforementioned regions under significant heat stress.

关键词： decadal changes dry heatwave wet heatwave eastern China

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金粟兰内酯A全合成中关键中间体的合成

四川农业大学学报 2012年第1期30卷 82-86页

作者：乐贵洲四川农业大学生命科学与理学院四川雅安625014

乌药烷型倍半萜金粟兰内酯A及类似物是一类有良好生物活性的分子,具有特殊的cis,trans-3-5-6三环骨架。对金粟兰内酯A进行了合成探索,以环己酮为起始原料经7步合成了关键中间体1,5-烯炔3。

关键词：倍半萜金粟兰内酯A 氧化合成

The role of proteasomes in tumorigenesis

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Genes & Diseases 2024年第4期11卷 155-169页

作者： Xiangyi zhou Ruqing Xu yue Wu Li zhou Tingxiu Xiang Department of Oncology The First Affliated Hospital of Chongqing Medical UniversityChongqing 400016China Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment Chongqing University Cancer HospitalChongqing 400030China

Protein homeostasis is the basis of normal life activities,and the proteasomefamily plays an extremely important function in this *** proteasome 2os is a concentric circle structure with twoαrings and twoβrings *** proteasome 2os can perform both ATP-dependent and non-ATP-dependent ubiquitination proteasome degradation by binding to various subunits(such as 19S,11S,and 200 PA),which is performed by its active subunitβ1,β2,andβ*** proteasome can degrade misfolded,excess proteins tomaintain *** the same time,it can be utilized by tumors to degrade over-proliferate and unwanted proteins to support their *** can affect the development of tumors from several aspects including tumor signaling pathways such as NF-kB and p53,cell cycle,immune regulation,and drug ***-encoding genes have been found to be overexpressed in a variety of tumors,providing a potential novel target for cancer *** addition,proteasome inhibitors such as bortezomib,carfilzomib,and ixazomib have been put into clinical application as the first-line treatment of multiple *** and more studies have shown that it also has different therapeutic effects in other tumors such as hepatocellular carcinoma,non-small cell lung cancer,glioblastoma,and ***,proteasome inhibitors are not much effective due to their tolerance and singleness in other ***,further studies on their mechanisms of action and drug interactions are needed to investigate their therapeutic potential.

关键词： Bortezomib Cancer therapy Immunoproteasome Multiplemyeloma Proteasome 20S Proteasome inhibitor Thymoproteasom

Analysis of China's Electricity Price and Electricity Burden of Basic Industries under the Carbon Peak Target before 2030

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 481-491页

作者： yue Qiu Suyang zhou Wei Gu Xiao-Ping Zhang School of Electrical Engineering Southeast UniversityNanjingChina School of Electronic Electrical and System EngineeringUniversity of BirminghamU.K.

The Chinese government is deepening reformation of electricity prices during the 14th Five Year Plan period and has set a carbon emission reduction target of reaching carbon peak before *** this context,will the carbon emission target influence electricity pricing and will electricity price influence competitiveness of Chinese main industries are two questions needing to be *** paper compares China's electricity price level with the selected major countries in the world,and four typical industries are selected to evaluate their electricity burden ***,the correlation between residential electricity price and industrial electricity price and the influencing factors is analyzed,from the perspectives of scale,structure and *** to the model obtained by regression analysis,the electricity price level and corresponding residential and industrial electricity burden in 2025 and 2030 are *** Terms-Electricity burden,industrial electricity price,regression analysis,residential electricity price.

关键词： Electricity burden industrial electricity price regression analysis residential electricity price