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Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

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Neural Regeneration Research 2025年第1期20卷 6-20页

作者： xiu-Yun Zhao De-En Xu Ming-Lei Wu Ji-chuan Liu Zi-Ling Shi Quan-Hong Ma Department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina Department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response

一种集成U-P的工作流建模方法与正确性分析

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计算机与现代化 2010年第2期 118-120页

作者：叶传秀赵美艳曲阜师范大学数学科学学院山东曲阜273165 济宁学院计算机系山东济宁272000

Petri网和统一建模语言UML是当前工作流建模领域两种非常流行、功能强大的建模工具。Petri网便于描述,可以动态地运行,但缺乏层次;UML可以完整、细致地刻画系统,但量化不够,缺乏有效、严密的分析工具与方法。本文整合两种建模方法的优点... 详细信息

Petri网和统一建模语言UML是当前工作流建模领域两种非常流行、功能强大的建模工具。Petri网便于描述,可以动态地运行,但缺乏层次;UML可以完整、细致地刻画系统,但量化不够,缺乏有效、严密的分析工具与方法。本文整合两种建模方法的优点,提出一种集成U-P建模的方法,该方法能够有效地描述系统,实现系统的模块化和模型重用,还能够对系统进行严密的分析,通过对模型仿真,找出其缺点和不足。

关键词：工作流 Petri网 UML

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Lévy风险模型的研究

曲阜师范大学学报（自然科学版） 2008年第2期34卷 47-50页

作者：赵永霞叶传秀曲阜师范大学数学科学学院山东省曲阜市273165

首先讨论了一般Lévy风险模型,得到了其折扣期望所满足的积分—微分方程;然后在Lévy风险过程有混合指数负跳的情况下,得到了一些特殊折扣期望的具体表达式.

关键词： Lévy过程 Laplace指数折扣期望

Structural characteristics,dispersion,and modification of fibrous brucite

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International Journal of Minerals,Metallurgy and Materials 2014年第1期21卷 82-88页

作者： Xi Cao xiu-yun chuan Key Laboratory of Orogen and Crust Evolution of the Education Ministry of China School of Earth and Space SciencesPeking University

Fibrous bmcite has very unique structure and physical properties. Brucite fibers were exfoliated into single nanofibers by using dioctyl sodium sulfosuccinate （AOT） as a dispersant through mechanical agitation and ultrasonic dispersion; and then, the nanofibers were modified by stearic acid and （3-aminopropyl）triethoxysilane （y-APS） compound modification agent. The nanofibers were characterized by using X-ray diffraction （XRD）, scanning electron microscopy （SEM）, transmission electron microscopy （TEM）, Fourier transform infrared spectroscopy （FTIR）, and thermal gravimetric analysis. It is found that AOT has good effect on the dispersion. The single fiber has a consis- tent morphology, and fibrous bmcite is dispersed and modified without destroying the crystal structure. Infrared and thermal analysis shows that the surface modification of fibrous brucite is achieved by forming chemical bonds between the coupling agent and magnesium hydroxide.

关键词： fibrous brucite dispersion nanofibers surface treatment modification

Constructing Order Two Superconvergent WG Finite Elements on Rectangular Meshes

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Numerical Mathematics(Theory,Methods and Applications) 2023年第1期16卷 230-241页

作者： xiu ye Shangyou Zhang Department of Mathematics University of Arkansas at Little RockLittle RockAR 72204USA Department of Mathematical Sciences University of DelawareNewarkDE 19716USA

In this paper,we introduce a stabilizer free weak Galerkin(SFWG)finite element method for second order elliptic problems on rectangular *** a special weak Gradient space,an order two superconvergence for the SFWG finite element solution is obtained,in both L 2 and H1 norms.A local post-process lifts such a Pk weak Galerkin solution to an optimal order Pk+2 *** numerical results confirm the theory.

关键词： Finite element weak Galerkin method stabilizer free rectangular mesh

Additive Maps Preserving Similarity of Operators on Banach Spaces

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Acta Mathematica Sinica,English Series 2006年第1期22卷 179-186页

作者： Jin chuan HOU xiu Ling ZHANG Department of Mathematics Shanxi Teachers University Linfen 041004 P R. China

Let X be an infinite-dimensional complex Banach space and denote by B（X） the algebra of all bounded linear operators acting on X. It is shown that a surjective additive map Φ from B（X） onto itself preserves similarity in both directions if and only if there exist a scalar c, a bounded invertible linear or conjugate linear operator A and a similarity invariant additive functional ψ on B（X） such that either Φ（T） = cATA^-1 ＋ ψ（T）I for all T, or Φ（T） = cAT＊A^-1 ＋ ψ（T）I for all T. In the case where X has infinite multiplicity, in particular, when X is an infinite-dimensional Hilbert space, the above similarity invariant additive functional ψ is always zero.

关键词： Additive maps on operator algebras Similarity of operators Banach spaces

FINITE ELEMENT METHODS FOR THE NAVIER-STOKES EQUATIONS BY H(div)ELEMENTS

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Journal of Computational Mathematics 2008年第3期26卷 410-436页

作者： Junping Wang Xiaoshen Wang xiu ye Division of Mathematical Sciences National Science Foundation Arlington VA 22230 USA Department of Mathematics University of Arkansas at Little Rock Little Rock AK 72204 USA

We derived and analyzed a new numerical scheme for the Navier-Stokes equations by using H（div） conforming finite elements. A great deal of effort was given to an establishment of some Sobolev-type inequalities for piecewise smooth functions. In particular, the newly derived Sobolev inequalities were employed to provide a mathematical theory for the H（div） finite element scheme. For example, it was proved that the new finite element scheme has solutions which admit a certain boundedness in terms of the input data. A solution uniqueness was also possible when the input data satisfies a certain smallness condition. Optimal-order error estimates for the corresponding finite element solutions were established in various Sobolev norms. The finite element solutions from the new scheme feature a full satisfaction of the continuity equation which is highly demanded in scientific computing.

关键词： Finite element methods Navier-Stokes equations CFD

Four-Order Superconvergent Weak Galerkin Methods for the Biharmonic Equation on Triangular Meshes

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Communications on Applied Mathematics and Computation 2023年第4期5卷 1323-1338页

作者： xiu ye Shangyou Zhang Department of Mathematics University of Arkansas at Little RockLittle RockAR72204USA Department of Mathematical Sciences University of DelawareNewarkDE19716USA

A stabilizer-free weak Galerkin(SFWG)finite element method was introduced and analyzed in ye and Zhang(SIAM ***.58:2572–2588,2020)for the biharmonic equation,which has an ultra simple finite element *** work is a continuation of our investigation of the SFWG method for the biharmonic *** new SFWG method is highly accurate with a convergence rate of four orders higher than the optimal order of convergence in both the energy norm and the L^(2)norm on triangular *** new method also keeps the formulation that is symmetric,positive definite,and ***-order superconvergence error estimates are proved for the corresponding SFWG finite element solutions in a discrete H^(2)*** of four orders in the L^(2)norm is also derived for k≥3,where k is the degree of the approximation *** postprocessing is proved to lift a P_(k)SFWG solution to a P_(k+4)solution elementwise which converges at the optimal *** examples are tested to verify the theor ies.

关键词： Finite element Weak Hessian Weak Galerkin(WG) Biharmonic equation Triangular mesh

Wave mode computing method using the step-split Padé parabolic equation

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Chinese Physics B 2022年第9期31卷 354-361页

作者： chuan-xiu Xu Guang-Ying Zheng Hangzhou Applied Acoustics Research Institute Hangzhou 310023China Science and Technology on Sonar Laboratory Hangzhou 310023China

Models based on a parabolic equation(PE)can accurately predict sound propagation problems in range-dependent ocean ***,this method has developed rapidly in recent *** with normal mode theory,PE focuses on numerical calculation,which is difficult to use in the mode domain analysis of sound propagation,such as the calculation of mode phase velocity and group *** broaden the capability of PE models in analyzing the underwater sound field,a wave mode calculation method based on PE is proposed in this ***-split Pade PE recursive matrix equations are combined to obtain a propagation ***,the eigenvalue decomposition technique is applied to the matrix to extract sound mode eigenvalues and *** experiments on some typical waveguides are performed to test the accuracy and flexibility of the new *** on different orders of Padéapproximant demonstrate angle limitations in PE and the missing root problem is also discussed to prove the advantage of the new *** PE mode method can be expanded in the future to solve smooth wave modes in ocean waveguides,including fluctuating boundaries and sound speed profiles.

关键词： parabolic equation propagation matrix eigenvalue decomposition