检索结果-南通市图书馆

Generation and regulation of electromagnetic pulses generated by femtosecond lasers interacting with multitargets

Nuclear Science and Techniques 2024年第1期35卷 96-107页

作者： Ya-Dong xia De-feng Kong Qiang-You He Zhen Guo Dong-Jun Zhang Tong yang Hao Cheng Yu-Ze Li yang Yan xiao Liang Ping Zhu Xing-Long Xie Jian-Qiang Zhu Ting-Shuai Li Chen Lin Wen-Jun Ma Xue-Qing Yan State Key Laboratory of Nuclear Physics and Technology and Key Laboratory of HEDP of the Ministry of EducationCAPTPeking UniversityBeijing 100871China Beijing Laser Acceleration Innovation Center Beijing 101407China Institute of Guangdong Laser Plasma Technology Guangzhou 510540China National Laboratory on High Power Laser and Physics Shanghai Institute of Optics and FineChinese Academy of SciencesShanghai 201800China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731China

Ultrashort and powerful laser interactions with a target generate intense wideband electromagnetic pulses(EMPs).In this study,we report EMPs generated by the interactions between petawatt(30 fs,1.4×10^(20) W/cm^(2))femtosecond(fs)lasers with metal flat,plastic flat,and plastic nanowire-array(NWA)*** analyses are conducted on the EMPs in terms of their spatial distribution,time and frequency domains,radiation energy,and *** results indicate that EMPs from metal targets exhibit larger amplitudes at varying angles than those generated by other types of targets and are enhanced significantly for NWA *** a plastic target holder and increasing the laser focal spot can significantly decrease the radiation energy of the ***,the composite shielding materials indicate an effective shielding effect against *** simulation results show that the NWA targets exert a collimating effect on thermal electrons,which directly affects the distribution of *** study provides guidance for regulating EMPs by controlling the laser focal spot,target parameters,and target rod material and is beneficial for electromagnetic-shielding design.

关键词： Electromagnetic pulses Laser plasma interaction Electromagnetic shielding Electron distribution

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ferroptosis mechanism and Alzheimer's disease

引用

Neural Regeneration Research 2024年第8期19卷 1741-1750页

作者： Lina feng Jingyi Sun Ling xia Qiang Shi Yajun Hou Lili Zhang Mingquan Li Cundong Fan Baoliang Sun Shandong Key Laboratory of TCM Multi-Target Intervention and Disease Control the Second Affiliated Hospital of Shandong First Medical UniversityTaianShandong ProvinceChina Department of Internal Medicine Taian Traffic HospitalTaianShandong ProvinceChina Department of Neurology the Third Affiliated Clinical Hospital of Changchun University of Chinese MedicineChangchunJilin ProvinceChina

Regulated cell death is a genetically determined form of programmed cell death that commonly occurs during the development of living *** process plays a crucial role in modulating homeostasis and is evolutionarily conserved across a diverse range of living *** is a classic regulatory mode of cell *** studies of regulatory cell death in Alzheimer’s disease have yielded increasing evidence that fe rroptosis is closely related to the occurrence,development,and prognosis of Alzheimer’s *** review summarizes the molecular mechanisms of ferroptosis and recent research advances in the role of ferro ptosis in Alzheimer’s *** findings are expected to serve as a theoretical and experimental foundation for clinical research and targeted therapy for Alzheimer’s disease.

关键词： Alzheimer’s disease apolipoprotein E Fe^(2+) ferroptosis glial cell glutathione peroxidase 4 imbalance in iron homeostasis lipid peroxidation regulated cell death system Xc^(-)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Metal-organic frameworks with dinuclear metal centers for synergistically boosting COphotoreduction

引用

Science China Chemistry 2024年

作者： Hui-feng Wang Wen-Jie Shi Yu-Xin yang Bao-xia Dong Tong-Bu Lu Di-Chang Zhong School of Chemistry and Chemical Engineering Yangzhou University Institute for New Energy Materials and Low Carbon Technologies School of Materials Science and Engineering Tianjin University of Technology

Dinuclear metal synergistic catalysis （DMSC） has been proved powerful in boosting CO2reduction,while this has not been achieved in heterogeneous catalysts with long-range order *** this study,we,by introduction of metal catalytic centers into an indium-based metal-organic framework （MOF）,obtained a series of isostructural In-MOFs,including three MOFs with mononuclear metal catalytic center （M-In）,three MOFs with dinuclear homometallic catalytic centers （MM-In）,and three MOFs with dinuclear heterometallic catalytic centers (MM’-In,M/M’=Co（II）,Ni（II）,Zn（II）).It was found that all these MOFs can serve as catalysts for photochemical CO2reduction to *** with M-In,the catalytic activities of MM-In were obviously enhanced,and that of MM’-In was further significantly *** example,the CO yield of CoZn-In reaches a record value of 12,700μmol g-1h-1,which is 4.0,8.1,9.4,and 18.6-fold higher than that of CoCo-In,ZnZn-In,Co-In,and Zn-In,***,the catalytic activities of CoNi-In and NiZn-In also show different fold increase than those of corresponding dinuclear homometallic and mononuclear metallic *** results of control experiments and theoretical calculation reveal that the higher catalytic activities of MM-In over M-In can be ascribed to the DMSC effect,and the higher catalytic activity of MM’-In over MM-In can be ascribed to the strengthened DMSC *** work reveals the relationship between DMSC effect and bimetal centers in CO2reduction,which provides new insights into the DMSC and paves a new way to design highly active catalysts for photochemical CO2reduction.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Variations in Column Concentration of Greenhouse Gases in China and Their Response to the 2015-2016 El Niño Event

引用

Journal of Meteorological Research 2024年第3期38卷 608-619页

作者： Ningwei LIU Lingjun xia Youjun DOU Shaorou DONG Jing WEN Ying WANG Rui feng Ruonan WANG Yuhe LI Institute of Atmospheric Environment China Meteorological AdministrationShenyang110166China Jiangxi Ecological Meteorology Centre Nanchang330096China Beijing xiangyuan Academy of Meteorological Observing Technology Beijing100081China Climate Centre of Guangdong Province Guangzhou510641China Guangdong Meteorological Service Guangzhou510062China Liaoning Provincial Meteorological Equipment Support Centre Shenyang110166China Meteorological Centre of Northeast Air Traffic Administration of Civil Aviation of China Shenyang110161China

Since the industrial revolution,enhancement of atmospheric greenhouse gas concentrations as a result of human activities has been the primary cause of global *** monitoring and evaluation of greenhouse gases are significant prerequisites for carbon emission *** monthly data of global atmospheric carbon dioxide(CO_(2))and methane(CH4)column concentrations(hereinafter XCO_(2) and XCH_(4),respectively)retrieved by the Greenhouse Gas Observation Satellite(GOSAT),we analyzed the variations in XCO_(2)and XCH_(4)in China during 2010-2022 after confirming the reliability of the ***,the influence of a strong El Niño event in 2015-2016 on XCO_(2) and XCH_(4) variations in China was further *** results show that the retrieved XCO_(2) and XCH_(4) from GOSAT have similar temporal variation trends and significant correlations with the ground observation and emission inventory data of an atmospheric background station,which could be used to assess the variations in XCO_(2) and XCH_(4) in ***_(2) is high in spring and winter while XCH_(4) is high in *** XCO_(2) and XCH_(4) gradually declined from Southeast China to Northwest and Northeast China,with variation ranges of 401-406 and 1.81-1.88 ppmv,respectively;and the high value areas are located in the middle-lower yangtze River ***_(2) and XCH_(4) in China increased as a whole during 2010-2022,with rapid enhancement and high levels of XCO_(2) and XCH_(4) in several *** significant increases in XCO_(2) and XCH_(4) over China in 2016 might be closely related to the strong El Niño-Southern Oscillation(ENSO)event during *** a global warming background in 2015,XCO_(2) and XCH_(4) increased by 0.768%and 0.657%in 2016 in *** analysis reveals that both the XCO_(2) and XCH_(4) variations might reflect the significant impact of the ENSO event on glacier melting in the Tibetan Plateau.

关键词： greenhouse gases column concentration CO_(2) CH4 El Niño-Southern Oscillation(ENSO) El Niño

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Highly Thermally Conductive Polydimethylsiloxane Composites with Controllable 3D GO@f-CNTs Networks via Self-sacrificing Template Method

引用

Chinese Journal of Polymer Science 2024年第7期42卷 897-906,I0005页

作者： Shuang-Shuang Wang Dian-Ying feng Zhi-Ming Zhang xia Liu Kun-Peng Ruan Yong-Qiang Guo Jun-Wei Gu Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’an710072China Shandong Institute of Nonmetallic Materials Jinan250031China Queen Mary University of London Engineering School Northwestern Polytechnical UniversityXi’an710072China

Constructing controllable thermal conduction networks is the key to efficiently improve thermal conductivities of polymer *** this work,graphite oxide(GO)and functionalized carbon nanotubes(f-CNTs)are combined to prepare“Line-Plane”-like hetero-structured thermally conductive GO@f-CNTs fillers,which are then performed to construct controllable 3D GO@f-CNTs thermal conduction networks via selfsacrificing template method based on oxalic ***,thermally conductive GO@f-CNTs/polydimethylsiloxane(PDMS)composites are fabricated via casting *** the size of oxalic acid is 0.24 mm and the volume fraction of GO@f-CNTs is 60 vol%,GO@f-CNTs/PDMS composites present the optimal thermal conductivity coefficient(λ,4.00 W·m^(-1)·K^(-1)),about 20 times that of theλof neat PDMS(0.20 W·m^(-1)·K^(-1)),also much higher than theλ(2.44 W·m^(-1)·K^(-1))of GO/f-CNTs/PDMS composites with the same amount of randomly dispersed ***,the obtained GO@f-CNTs/PDMS composites have excellent thermal stability,whoseλdeviation is only about 3%after 500 thermal cycles(20-200℃).

关键词： Polydimethylsiloxane Hetero-structured thermally conductive fillers Self-sacrificing template Thermal conduction networks

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Assessment of pathogenicity and functional characterization of APPL1 gene mutations in diabetic patients

引用

World Journal of Diabetes 2024年第2期15卷 275-286页

作者： Ping Shi yang Tian feng Xu Lu-Na Liu Wan-Hong Wu Ying-Zhou Shi An-Qi Dai Hang-Yu Fang Kun-xia Li Chao Xu Department of Endocrinology Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021Shandong ProvinceChina Department of Pediatric Yantai Yuhuangding Hospital Affiliated to Qingdao UniversityYantai 264099Shandong ProvinceChina

BACKGROUND Adaptor protein,phosphotyrosine interacting with PH domain and leucine zipper 1(APPL1)plays a crucial role in regulating insulin signaling and glucose *** in the APPL1 gene have been associated with the development of maturity-onset diabetes of the young type 14(MODY14).Currently,only two mutations[c.1655T>A(***552*)and c.281G>A p.(Asp94Asn)]have been identified in association with this *** the limited understanding of MODY14,it is imperative to identify additional cases and carry out comprehensive research on MODY14 and APPL1 *** To assess the pathogenicity of APPL1 gene mutations in diabetic patients and to characterize the functional role of the APPL1 *** Patients exhibiting clinical signs and a medical history suggestive of MODY were screened for the *** exome sequencing was performed on the patients as well as their family *** pathogenicity of the identified APPL1 variants was predicted on the basis of bioinformatics *** addition,the pathogenicity of the novel APPL1 variant was preliminarily evaluated through in vitro functional ***,the impact of these variants on APPL1 protein expression and the insulin pathway were assessed,and the potential mechanism underlying the interaction between the APPL1 protein and the insulin receptor was further *** A total of five novel mutations were identified,including four missense mutations(Asp632Tyr,Arg633His,Arg532Gln,and Ile642Met)and one intronic mutation(1153-16A>T).Pathogenicity prediction analysis revealed that the Arg532Gln was pathogenic across all *** Asp632Tyr and Arg633His variants also had pathogenicity based on *** addition,multiple alignment of amino acid sequences showed that the Arg532Gln,Asp632Tyr,and Arg633His variants were conserved across different ***,in in vitro functional experiments,both the c.1894G>T(at Asp632Tyr)and c.1595G>A(at Arg532Gln)mutations

关键词： Adaptor protein,phosphotyrosine interacting with PH domain and leucine zipper 1 Maturity-onset diabetes of the young Bioinformatics analysis Gene mutation Domain

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Investigating Sulfur Chemistry in the HD163296 Disk

引用

Research in Astronomy and Astrophysics 2024年第7期24卷 215-225页

作者： Rong Ma Donghui Quan Yan Zhou Jarken Esimbek Dalei Li xiaohu Li xia Zhang Juan Tuo Yanan feng Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China University of Chinese Academy of Sciences Beijing 100049China Research Center for Intelligent Computing Platforms Zhejiang LaboratoryHangzhou 311100China BinZhou University Binzhou 256600China Key Laboratory of Radio Astronomy Chinese Academy of SciencesUrumqi 830011China Xinjiang Key Laboratory of Radio Astrophysics Urumqi 830011China

Sulfur chemistry in the formation process of low-mass stars and planets remains poorly *** protoplanetary disks are the birthplace of planets and its distinctive environment provides an intriguing platform for investigating models of sulfur *** analyzed the Atacama Large Millimeter/submillimeter Array observations of CS 7-6 transitions in the HD 163296 disk and performed astrochemical modeling to explore its sulfur *** simulated the distribution of sulfur-containing molecules and compared it with observationally deduced fractional column *** have found that the simulated column density of CS is consistent with the observationally deduced fractional column densities,while the simulated column density of C_(2)S is lower than the observationally deduced upper limits on column *** results indicate that we have a good understanding of the chemical properties of CS and C_(2)S in the *** also investigated the influence of the C/O ratio on sulfur-containing molecules and found that the column densities of SO,SO_(2),and H_2S near the centra star are dependent on the C/O ***,we found that the N[CS]/N[SO]ratio can serve as a promising indicator of the disk’s C/O ratio in HD ***,the disk of HD 163296 provides a favorable environmen for the detection of sulfur-containing molecules.

关键词： Protoplanetary Disks-Astrochemistry-Molecular Processes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

纳米铜润滑油添加剂的摩擦学特性及其自修复机理

引用

材料保护 2018年第2期51卷 22-25页

作者：杨峰夏晓雷徐创徐州工程学院机电工程学院江苏徐州221018

为了评价纳米铜添加剂对摩擦副的减摩和自修复性能,采用液相化学还原法合成了二烷基二硫代磷酸(HDDP)修饰纳米铜微粒,利用四球摩擦磨损试验机分析了不同载荷条件下纳米铜添加量对摩擦系数、磨斑直径等摩擦学性能影响,采用扫描电镜(SEM)... 详细信息

为了评价纳米铜添加剂对摩擦副的减摩和自修复性能,采用液相化学还原法合成了二烷基二硫代磷酸(HDDP)修饰纳米铜微粒,利用四球摩擦磨损试验机分析了不同载荷条件下纳米铜添加量对摩擦系数、磨斑直径等摩擦学性能影响,采用扫描电镜(SEM)和X射线光电子能谱仪(XPS)分析了磨痕形貌及其化学成分组成,并通过纳米压痕测试技术测量铜膜硬度及弹性模量。结果表明:纳米铜添加量为0.4%(质量分数)时减摩效果最佳,磨斑直径和摩擦系数明显下降,比未添加纳米铜的降低了23.0%~27.2%和15.1%~24.9%。摩擦过程中纳米铜微粒在摩擦表面形成化学沉积膜,铜膜的纳米硬度为1.63 GPa,弹性模量为78.08 GPa,表现出优良的抗磨减摩性能。

关键词：纳米铜添加剂润滑油抗磨减摩自修复性能

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Leech Poecilobdella manillensis protein extract ameliorated hyperuricemia by restoring gut microbiota dysregulation and affecting serum metabolites

引用

World Journal of Gastroenterology 2024年第29期30卷 3488-3510页

作者： xia Liu Xing-Qiu Liang Tian-Cai Lu Zhe feng Min Zhang Nan-Qing Liao feng-Lian Zhang Bo Wang Li-Sheng Wang Medical College Guangxi UniversityNanning 530004Guangxi Zhuang Autonomous RegionChina Department of Traditional Chinese Medicine HIV/AIDS Clinical Treatment Center of Guangxi(Nanning)The Fourth People’s Hospital of NanningNanning 530023Guangxi Zhuang Autonomous RegionChina Department of Science and Technology Ruikang Hospital Affiliated to Guangxi University of Chinese MedicineNanning 530011Guangxi Zhuang Autonomous RegionChina General Manager’s Office Guangxi Fuxinyi Biological Technology Co.Ltd.Pingnan 537300Guangxi Zhuang Autonomous RegionChina Department of Joint and Sports Medicine Ruikang Hospital Affiliated to Guangxi University of Chinese MedicineNanning 530011Guangxi Zhuang Autonomous RegionChina Department of Gerontology Nanning Social Welfare HospitalNanning 530004Guangxi Zhuang Autonomous RegionChina

BACKGROUND Hyperuricemia(HUA)is a public health concern that needs to be solved *** lyophilized powder of Poecilobdella manillensis has been shown to significantly alleviate HUA;however,its underlying metabolic regulation remains *** To explore the underlying mechanisms of Poecilobdella manillensis in HUA based on modulation of the gut microbiota and host *** A mouse model of rapid HUA was established using a high-purine diet and potassium oxonate *** mice received oral drugs or ***,16S rRNA sequencing and ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry-based untargeted metabolomics were performed to identify changes in the microbiome and host metabolome,*** levels of uric acid transporters and epithelial tight junction proteins in the renal and intestinal tissues were analyzed using an enzyme-linked immunosorbent *** The protein extract of Poecilobdella manillensis lyophilized powder(49 mg/kg)showed an enhanced anti-trioxypurine ability than that of allopurinol(5 mg/kg)(P<0.05).A total of nine bacterial genera were identified to be closely related to the anti-trioxypurine activity of Poecilobdella manillensis powder,which included the genera of Prevotella,Delftia,Dialister,Akkermansia,Lactococcus,Escherichia_Shigella,Enterococcus,and ***,22 metabolites in the serum were found to be closely related to the anti-trioxypurine activity of Poecilobdella manillensis powder,which correlated to the Kyoto Encyclopedia of Genes and Genomes pathways of cysteine and methionine metabolism,sphingolipid metabolism,galactose metabolism,and phenylalanine,tyrosine,and tryptophan *** analysis found that changes in the gut microbiota were significantly related to these *** The proteins in Poecilobdella manillensis powder were effective for ***,they are associated with improvements in g

关键词： Gut microbiota Metabolism Multi-omics Poecilobdella manillensis Sphingolipid metabolism pathway Galactose metabolism pathway Hyperuricemia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

偏高岭土水热合成NaY分子筛的机理研究

引用

无机化学学报 2008年第2期24卷 235-240页

作者：王雪静张甲敏杨胜凯杨风霞河南科技学院化学化工学院新乡453003

采用茂名高岭土水热合成NaY分子筛,用IR,XRD,NMR,SEM,HRTEM等分析了其晶化过程。结果表明:偏高岭土水热合成Y型分子筛是固相转变机理,晶化过程是一个扩散-成胶-原位重排的过程。

关键词：偏高岭土 NaY分子筛机理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：