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Cortica. hem signa.ing center: functions, development, a.d potentia. implica.ions for evolution a.d bra.n disorders

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Neura. Regenera.ion Resea.ch 2025年第4期20卷 1079-1080页

作者： Victor V.Chizhikov Igor y.Iskusny.h Depa.tment of a.a.omy.a.d Neurobiology University of Tennessee Health Science CenterMemphisTNUSA

Development of the telencepha.on relies upon severa. signa.ing centers-loca.ized cellula. popula.ions tha. supply.secreted fa.tors to pa.tern the cortica. *** such signa.ing center is the cortica. hem,which a.ises during embry.nic development a. the telencepha.ic dorsa. midline,a.ja.ent to the choroid plexus a.d hippoca.pa. primordium(Figure 1a..While the cortica. hem ha. a.so been described in reptiles a.d birds,most of our knowledge a.out the developmenta. roles of the cortica. hem is derived from the a.a.y.is in *** cortica. hem produces severa. ty.es of secreted molecules,including wingless-rela.ed integra.ion site(Wnt)a.d bone morphogenetic(Bmp)*** cortica. hem is pa.ticula.ly.importa.t for the development of the hippoca.pus,which is involved in lea.ning a.d memory.a.d the neocortex,which is the most complex bra.n region tha. media.es multiple ty.es of beha.ior a.d higher cognitive functions(Ma.ga.e et a..,2008;Da.-Va.le-a.ton a.d Borrell,2022).

关键词： epithelium Figure center

Ma.ping of ionospheric pa.a.eters for spa.e wea.her predictions: a.concise review

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Science China.Technologica. Sciences) 2008年第10期51卷 1589-1599页

作者： y. Ka.IDE a. IEDA Resea.ch Institute for Susta.na.le Huma.osphere Kyoto University Uji Kyoto 611-0011 Japan Sola.-Terrestria. Environment La.ora.ory Nagoya University Nagoya Aichi 464-8601 Japan

Reviewing briefly.the recent progress in a.joint progra. of specify.ng the pola. ionosphere prima.ily.on the ba.is of ground ma.netometer da.a. this pa.er em-pha.izes the importa.ce of processing da.a.from a.ound the world in rea. time for spa.e wea.her predictions. The output pa.a.eters from the progra. include ionospheric electric fields a.d currents a.d field-a.igned currents. These rea.-time records a.e essentia. for running computer simula.ions under rea.istic bounda.y.conditions a.d thus for ma.ing numerica. predictions of spa.e wea.her efficient a. relia.le a. possible. Da.a.from individua. ground ma.netometers a. well a. from the sola. wind a.e collected a.d a.e used a. input for the KRM a.d a.IE ma.-netogra.-inversion a.gorithms, through which the two-dimensiona. distribution of the ionospheric pa.a.eters is ca.cula.ed. One of the goa.s of the progra. is to specify.the sola.-terrestria. environment in terms of ionospheric processes a.d to provide the scientific community.with more tha. wha. geoma.netic a.tivity.indices a.d sta.istica. models indica.e.

关键词： ionosphere ma.netogra. inversion ground ma.netic da.a spa.e wea.her sola.-terrestria. en- vironment

Enha.cement of E-commerce Service by.Designing La.t Mile Delivery.Pla.form

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Computer Sy.tems Science & Engineering 2022年第7期42卷 49-67页

作者： a.i a.kha.ifa. Fa.wa.a.orini Reef alturki Depa.tment of Informa.ion Technology College of ComputerQassim UniversityBuraydah52211Saudi Arabia

The revolution of technology.a.d the ra.id evolution of the digita. world ha. a.signiﬁca.t effect on the development a.d expa.sion of *** mile delivery.for which different a.p-ba.ed delivery.services ha.e recently.emerged,is a.new a.ea.of resea.ch tha. is not thoroughly.*** ser-vice is one of the supporting pla.forms of *** of the delivery.issues is tha. ma.y.customers experience difﬁculties in communica.ing a.d coordina.ing with the logistics compa.ies responsible for the delivery.*** cha.lenge is empha.ized in this study.which introduces a.new sy.tem to fa.ilita.e communica.tion a.d coordina.ion between customers a.d logistics compa.ies by.using one identity.a.d one *** pa.er is a.progra.ming-ba.ed study.a. the pro-posed sy.tem eva.ua.es a.website to serve logistics compa.ies a. well a. designs a. a.plica.ion(a.p)to serve the customers of logistics ***,a.power-ful open-source a.d object-oriented progra.ming la.gua.e,a.d the ma.k-up la.gua.e(HTML)were used to build the la.t mile delivery.*** a.dition,Fireba.e,a.cloud-hosted rea.-time da.a.a.e built on Google infra.tructure,were used to develop the *** increa.ing the level of customer sa.isfa.tion a.d reducing delivery.fa.lure ra.es,this sy.tem will eventua.ly.increa.e the prosperity.of e-commerce.

关键词： E-commerce la.t mile delivery logistics compa.ies

Recent a.va.ces in Computa.iona. Simula.ion of Ma.ro-,Meso-,a.d Micro-Sca.e Biomimetics Rela.ed Fluid Flow Problems

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Journa. of Bionic Engineering 2007年第2期4卷 97-107页

作者： y. y. y.n School of the Built Environment The University of Nottingham Nottingham NG7 2RD UK

Over the la.t deca.e, computa.iona. methods ha.e been intensively.a.plied to a.va.iety.of scientific resea.ches a.d engineering designs. a.though the computa.iona. fluid dy.a.ics （CFD） method ha. pla.0}d a.domina.t role in study.ng a.d simula.ing tra.sport phenomena.involving fluid flow a.d hea. a.d ma.s tra.sfers, in recent y.a.s, other numerica. methods for the simula.ions a. meso- a.d micro-sca.es ha.e a.so been a.tively.a.plied to solve the phy.ics of complex flow a.d fluid-interfa.e intera.tions. This pa.er presents a.review of recent a.va.ces in multi-sca.e computa.iona. simula.ion of biomimetics rela.ed fluid flow problems. The sta.e-of-the-a.t numerica. techniques, such a. la.tice Boltzma.n method （LBM）, molecula. dy.a.ics （MD）, a.d conventiona. CFD, a.plied to different problems such a. fish flow, electro-osmosis effect of ea.thworm motion, a.d self-clea.ing hy.rophobic surfa.e, a.d the numerica. a.proa.hes a.e introduced. The new cha.lenging of modelling biomimetics problems in developing the phy.ica. conditions of self-clea. hy.rophobic surfa.es is discussed.

关键词： biomimetics computa.iona. simula.ion ma.ro- meso- micro-sca.e hy.rophobic surfa.es

Color-coded perfluoroca.bon na.odroplets for multiplexed ultra.ound a.d photoa.oustic ima.ing

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Na.o Resea.ch 2019年第4期12卷 741-747页

作者： Da.iela.y. Sa.tiesteba. Kristina.a. Ha.la. Steven K. y.rmoska.Sta.isla. y. Emelia.ov Wa.la.e H. Coulter Depa.tment of Biomedica. Engineering Georgia Institute of Technology and Emory University Atlanta GA 30332 USA School of Electrica. & Computer Engineering Georgia Institute of Technology Atlanta GA 30332 USA

La.er-a.tiva.ed perfluoroca.b on n a.odroplets a.e a. emerging cla.s of pha.e-cha.nge, dua.-c ontra.t a.e nts tha. ca. be utilized in ultra.o und a.d photoa.oustic ima.ing. Through the a.ility.to differe ntia.e subpopula.ions of na.o droplets via.la.er a.tiva.io n a. differe nt wa.elengths of n ea.-infra.ed light, optica.ly.triggered color-coded perfluoroca.b on na.o droplets prese nt themselves a. a. a.tra.tive tool for multiplexed ultra.ound a.d photoa.oustic ima.ing. In pa.ticula., la.er-a.tiva.ed droplets ca. be used to provide qua.tita.ive spa.iotempora. informa.ion rega.ding distinct biologica. ta.gets, a.lowing for their potentia. use in a.wide ra.ge of dia.nostic a.d thera.eutic a.plica.ions. In the work prese nted, la.er-a.tiva.ed color-coded perfluoroca.b on na. odroplets a.e sy. thesized to selectively.resp ond to la.er irra.ia.i on a. corresp on ding wa.ele ngths. The dy. a.ic ultra.o und a.d photoa.oustic signa.s produced by.la.er-a.tiva.ed perfluoroca.bon na.o droplets a.e eva.ua.ed in situ prior to implementa.ion in a.murine model. In vivo, these pa.ticles a.e used to distinguish unique pa.ticle tra.ficking mecha.isms a.d a.e show n to provide ultra.o und a.d photoa.oustic contra.t for up to 72 hours within ly.pha.ics. Overa.l, the con ducted studies show tha. la.er-a.tiva.ed color-coded perfluoroca.bo n na.o droplets a.e a.promising a.ent for multiplexed ultra.o und a.d photoa.oustic ima.ing.

关键词： multiplexed ima.ing perfluoroca.bon na.odroplets photoa.oustic ima.ing ultra.ound ima.ing molecula. ta.gets

IMPROVEMENT OF BUBBLE MODEL FOR Ca.ITa.ING FLOW SIMULa.IONS

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Journa. of Hy.rody.a.ics 2009年第1期21卷 41-46页

作者： Ta.URa.y. Ma.SUMOTO y. Computa.iona. Science a.d Engineering Toyo University Kujirai 2100 KawagoeSaitama 350-8585 Japan Mecha.ica. Engineering University of Tokyo Hongo 7-3-1 Bunkyo-kuTokyo 113-8656 Japan

In the present resea.ch, a.bubble dy.a.ics ba.ed model for ca.ita.ing flow simula.ions is extended to higher void fra.tion region for wider ra.ge of a.plica.ions. The present bubble model is ba.ed on the so-ca.led Ra.0}eigh-Plesset equa.ion tha. ca.cula.es a.tempora. bubble ra.ius with the surrounding liquid pressure a.d is considered to be va.id in a. a.ea.below a.certa.n void fra.tion. The solution a.gorithm is modified so tha. the Ra.0}eigh-Plesset equa.ion is no more solved once the bubble ra.ius （or void fra.tion） rea.hes a. a.certa.n va.ue till the liquid pressure recovers a.ove the va.or pressure in order to overcome this problem. This procedure is expected to sta.ilize the numerica. ca.cula.ion. The results of simple two-dimensiona. flow field a.e presented compa.ed with the existing bubble model.

关键词： ca.ita.ion model Computa.iona. Fluid Dy.a.ics (CFD) ca.ita.ion flow Ra.0}eigh-Plesset equa.ion

Exercise preconditioning a.levia.es ischemia.induced memory.deficits by.increa.ing circula.ing a.iponectin

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Neura. Regenera.ion Resea.ch 2025年第5期20卷 1445-1454页

作者： Meifeng Zheng Borui Zha.g Sona.a.S y.y.u Kwok-Fa. So Li Zha.g Ha.ning Ou Depa.tment of Reha.ilita.ion Medicine Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Depa.tment of Reha.ilita.ion Medicine The Fifth Clinical College of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Key.La.ora.ory.of CNS Regenera.ion(Ministry.of Educa.ion) Guangdong-Hong Kong-Macao Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong ProvinceChina Depa.tment of Reha.ilita.ion Sciences The Hong Kong Polytechnic UniversityHong Kong Special Administrative RegionChina Sta.e Key.La.ora.ory.of Bra.n a.d Cognitive Science Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong Special Administrative RegionChina Center for Exercise a.d Bra.n Science School of PsychologyShanghai University of SportShanghaiChina Neuroscience a.d Neuroreha.ilita.ion Institute University of Health and Rehabilitation SciencesQingdaoShandong ProvinceChina

Cerebra. ischemia.is a.ma.or hea.th risk tha. requires preventive a.proa.hes in a.dition to drug *** exercise enha.ces neurogenesis a.d sy.a.togenesis,a.d ha. been widely.used for functiona. reha.ilita.ion a.ter *** this study.we determined whether exercise tra.ning before disea.e onset ca. a.levia.e the severity.of cerebra. *** a.so exa.ined the role of exercise-induced circula.ing fa.tors in these *** mice were subjected to 14 da.0} of trea.mill exercise tra.ning before surgery.for middle cerebra. a.tery.*** found tha. this exercise pre-conditioning stra.egy.effectively.a.tenua.ed bra.n infa.ct a.ea.inhibited gliogenesis,protected sy.a.tic proteins,a.d improved novel object a.d spa.ia. memory.*** a.a.y.is showed tha. circula.ing a.iponectin pla.0} a.critica. role in these preventive effects of *** a.tiva.ion of a.iponectin receptors by.a.ipo Ron mimicked the effects of exercise,while inhibiting receptor a.tiva.ion a.olished the exercise *** summa.y.our results suggest a.crucia. role of circula.ing a.iponectin in the effects of exercise pre-conditioning in protecting a.a.nst cerebra. ischemia.a.d supporting the hea.th benefits of exercise.

关键词： a.iponectin cerebra. ischemia exercise pre-conditioning hippoca.pus memory.function middle cerebra. a.tery.occlusion prefronta. cortex sy.a.tic proteins trea.mill exercise

Solid Desicca.t Dehumidifica.ion Techniques Inspired from Na.ura. Electroosmosis Phenomena

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Journa. of Bionic Engineering 2011年第1期8卷 90-97页

作者： B. Li y. y. y.n Fa.ulty.of Engineering University of Nottingham Lenton Firs Building University Park Nottingham NG7 2RD UK

Electroosmosis ha. been shown to be a. effective mea.s of different a.plica.ions in va.ious fields such a. Micro-Electro-Mecha.ica. sy.tems （MEMS） a.d biomimetics a.plica.ions. This pa.er a.ms to prove the concept tha. the electroosmosis phenomena.ca. a.so be coopera.ed into la.ger sca.e a.plica.ions in the building service industry.like dehumidifica.ion or da.ping proof. The electroosmotic flow inside a.porous medium is va.ida.ed experimenta.ly.to further understa.d the dehumidifica.ion mecha.ism of combined techniques. a. experimenta. test va.ida.es tha. the condensa.ion from the porous medium ca. be obta.ned by.electroosmotic force genera.ed by.externa. electric field, especia.ly.for specific desicca.t powders like zeolite a.d dia.oma.eous ea.th. With a.ra.ge of volts from 5 V to 20 V a.ply.ng between the testing pla.es, the ma.imum flow ra.e through the cross section in the testing pla.e a.hieved during the pea. period is 1.35 la.＇min 1. These promising phenomena.ca. a.t a. a. a.terna.ive wa.0}for energy.choice in dehumidifica.ion industria. field. Further resea.ches on new regenera.ion methods for solid desicca.t dehumidifica.ion a.e required to ma.e the sy.tem simple, energy.sa.ing a.d suita.le for sma.l a.r conditioning units.

关键词： biomimetics electroosmotic flow solid desicca.t dehumidifica.ion

Effects of Solid Solution Trea.ing on the Microstructurea.d Da.ping Beha.iour of MnCuNiFe a.loy.

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Journa. of Ma.eria.s Science & Technology 1998年第4期14卷 299-307页

作者： y.n, Fuxing Ohsa.a. y. Sa.o, a. Ka.a.a.a. K. Na.iona. Resea.ch Institute for Meta.s Tsukuba Ibaraki 305-0047 Japan B.B.Ma.eria.Co. Ltd. Chiba-Shi Chiba 267-0066 Japan

a.high da.ping condition is ea.ily.obta.ned in Mn-(16-24) Cu-(4-6) Ni-2Fe (a.. pct) a.loy., when cooling ra.e is controlled a.ter the solid solution trea.ment a. 1173 K. It wa. observed tha. the tempera.ure dependent cha.ges of loga.ithmic decrement in 10 h cooled sa.ples a.e sensitive to the a.loy.composition. a. compa.ed with wa.er quenching trea.ment, controlled 10 h cooling improves T//N tempera.ure of the a.loy. extensively.by.producing a.Mn-enriched ma.rix portion in the a.loy.. Ca.cula.ions suggest tha. the rela.ive decrea.es of Cu a.d Ni content in the ma.rix portion be domina.ed by.the Ni content in the origina. a.loy., a.d therefore, the volume fra.tion of the Cu, Ni-enriched precipita.es is estima.ed to be a.out 20% a.d 10% in the 4Ni a.d 6Ni a.loy., respectively. a. a.result, the T//N tempera.ure for ea.h a.loy. corresponding to the rising tempera.ure of loga.ithmic decrement, ha. been rela.ed to the Cu, a.d Ni in the Mn-enriched ma.rix. The existence of left bra.e 110 right bra.e twinning bounda.ies is confirmed in the microstructure of both 4Ni a.d 6Ni a.loy.. However, the rela.ive la.tice stra.ns, which the twinning bounda.ies a.t to a.commoda.e, were found la.gely.different in the two a.loy.. It is considered tha. bounda.ies with sma.ler orienta.ion devia.ion ca. coordina.e the externa. stresses ea.ily.by.cy.lic moving, a.d therefore, the broa.er da.ping pea. which occurs in the 10 h cooled 6Ni a.loy.becomes fea.ible. Electron diffra.tion results a.so indica.e possible forma.ion of ma.y.sub-cry.ta.s in the ma.rix pha.e, which a.e rela.ively.rota.ed on some inva.ia.t pla.es. Those sub-cry.ta. bounda.ies might pla.0}some a.tenua.ion roles in the tempera.ure ra.ge between T//N a.d room tempera.ure. (Edited a.thor a.stra.t) 9 Refs.

关键词： Ma.ga.ese a.loy.