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Effects of methylprednisolone or immunoglobulin when added to standard treatment with intravenous azithromycin for refractory Mycoplasma pneumoniae pneumonia in children

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World Journal of Pediatrics 2017年第4期13卷 321-327页

作者： Li-Shen Shan xin Liu xin-yuan kang Fei Wang Xiao-Hua Han Yun-Xiao Shang Department of Pediatric Pulmonology Shengjing Hospital of China Medical UniversityShenyangChina China Medical University ShenyangChina

Background:The prevalence of Mycoplasma pneumoniae pneumonia has increased considerably in recent *** evaluate the efficacy of combined treatment of azithromycin with intravenous immunoglo-bulin (IVIG) or methylprednisolone in children with refractory Mycoplasma pneumoniae pneumonia (RMPP).Methods:Children with RMPP were randomly allocated to group A [intravenous azithromycin (IA)+ methylprednisolone],group B (IA+IVIG) or group C (IA alone).Following a 7-day treatment,group C patients were randomly separated into two sub-groups:group C1 (IA+methylprednisolone) and group C2 (IA+IVIG).Temperature,respiratory symptoms and signs were *** average febrile period after treatment (F2),average total febrile period (F3),infiltration absorption,atelectasis resolution,pleural effusion disappearance were *** levels of C-reactive protein (CRP),D-dimer,and lactate dehydrogenase (LDH) were ***:Seven days after enrollment,the average F2 after treatment of group A was the *** with the control group C,the combined treatment group A and B showed higher rates of infiltration absorption,atelectasis resolution and pleural effusion disappearance,while lower levels of serum CRP,D-dimer and *** days after enrollment,all children with combined therapy clinically improved,and presented better laboratory *** C1 showed shorter F3 and lower levels of CRP and LDH than those of group ***,group A showed the shortest F3,also has the lowest CRP and ***:Azithromycin with IVIG or methylprednisolone was better treatment for children with RMPP than azithromycin *** treatment may be beneficial,especially when the efficacy of corticosteroids is insecure,thus could be considered as an alternative of primary therapeutic approaches.

关键词： immunoglobulin methylprednisolone refractory Mycoplasma pneumoniae pneumonia

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Competition of Composition Fluctuation Modes in Weakly Segregated Salt-doped Symmetric Diblock Copolymers

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Chinese Journal of Polymer Science 2024年第9期42卷 1375-1385,I0008页

作者： yuan-xin Zhou Xian Kong South China Advanced Institute for Soft Matter Science and Technology School of Emergent Soft MatterSouth China University of TechnologyGuangzhou510640China Guangdong Provincial Key Laboratory of Functional and Intelligent Hybrid Materials and Devices South China University of TechnologyGuangzhou510640China

Salt-doped block copolymers have widespread applications in batteries,fuel cells,semiconductors,and various industries,where their properties crucially depend on phase separation ***,investigations into salt-doped diblock copolymers have predominantly focused on microphase separation,overlooking the segregation between ionic and polymeric *** study employs weak segregation theory to explore the interplay between phase separation dominated by the polymer-modulated mode and the salt-out-modulated mode,corresponding to microscopic and macroscopic phase separations,*** comparing diblock copolymers doped with salts to those doped with neutral solvents,we elucidate the significant role of charged species in modulating phase *** phase separation mode exhibits a transition between the polymer-modulated and salt-out-modulated modes at different *** systems doped with neutral solvents,this transition is stepwise,while in salt-ion-doped systems,it is *** a sufficiently large Flory-Huggins parameter between ions and polymers,the salt-out-modulated mode becomes dominant,promoting macrophase *** to the solvation effect of salt ions,salt-doped systems are more inclined to undergo microphase ***,we explore factors influencing the critical wavenumber of phase separation,including doping level and the Flory-Huggins parameters between two blocks and between ions and polymeric *** findings reveal that in a neutral solvent environment,these factors alter only the boundary between micro-and macro-phase separations,leaving the critical wavenumber unchanged in microphase separation ***,in a salt-doped environment,the critical wavenumber of microphase separation varies with these *** provides valuable insights into the pivotal role of electrostatics in the phase separation of salt-doped block copolymers.

关键词： Block copolymer Phase separation Field theory Salt-doped

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SDGNN: Symmetry-Preserving Dual-Stream Graph Neural Networks

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IEEE/CAA Journal of Automatica Sinica 2024年第7期11卷 1717-1719页

作者： Jiufang Chen Ye yuan xin Luo the College of Computer Science and Technology Chongqing University of Posts and TelecommunicationsChongqing 400065 the Chongqing Key Laboratory of Big Data and Intelligent Computing Chongqing Institute of Green and Intelligent TechnologyChinese Academy of SciencesChongqing 400714China the College of Computer and Information Science Southwest UniversityChongqing 400715China IEEE

Dear Editor,This letter proposes a symmetry-preserving dual-stream graph neural network(SDGNN) for precise representation learning to an undirected weighted graph(UWG). Although existing graph neural networks(GNNs) are influential instruments for representation learning to a UWG, they invariably adopt a unique node feature matrix for illustrating the sole node set of a UWG.

关键词： representation preserving undirected

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Recent Progress and Regulation Strategies of Layered Materials as Cathode of Aqueous Zinc-Ion Batteries

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Energy & Environmental Materials 2024年第3期7卷 14-31页

作者： yuan yuan Si Wu Xiaoxue Song Jin Yong Lee Baotao kang School of Chemistry and Chemical Engineering University of JinanJinan 250022China Department of Chemistry Sungkyunkwan UniversitySuwon 16419Korea Shandong Hi-Speed Engineering Test Co. Ltd.Jinan 250022China

Aqueous zinc-ion batteries(ZIBs)have shown great potential in the fields of wearable devices,consumer electronics,and electric vehicles due to their high level of safety,low cost,and multiple electron *** layered cathode materials of ZIBs hold a stable structure during charge and discharge reactions owing to the ultrafast and straightforward(de)intercalation-type storage mechanism of Zn^(2+)ions in their tunable interlayer spacing and their abilities to accommodate other guest ions or ***,the challenges of inadequate energy density,dissolution of active materials,uncontrollable byproducts,increased internal pressure,and a large de-solvation penalty have been deemed an obstacle to the development of *** this review,recent strategies on the structure regulation of layered materials for aqueous zinc-ion energy storage devices are systematically ***,critical science challenges and future outlooks are proposed to guide and promote the development of advanced cathode materials for ZIBs.

关键词： layered cathode materials modifying strategies structure regulation zinc-ion batteries

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Numerical Analysis of Heat Transfer Characteristics to Supercritical CO_(2) in a Vertical Mini-Channel:Transition and Pseudo-Boiling

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Journal of Thermal Science 2024年第1期33卷 101-113页

作者： yuan Baoqiang WANG Wei xin Gongming DU Wenjing School of Energy and Power Engineering Shandong UniversityJi'nan 250061China

Large eddy simulations have been conducted to study upward transitional flows and heat transfer characteristics of supercritical CO_(2) in a vertical *** numerical simulation was carried out on a modified buoyantPimpleFOAM solver in OpenFOAM 7,and was verified using experiment *** results indicate that increasing the Grashof numbers can reduce the flow stability and make the flow transition *** are four stages of heat transfer in the transition process,i.e.,weakened,improved,recovered and normal heat *** heat transfer phenomena in the transition process were explained from three perspectives:thermal boundary layer theory,turbulent transport and pseudo-boiling *** transfer enhancement during transition is related to the transport of supercritical molecular clusters,and these molecular clusters are regarded as pseudo-bubbles in pseudo-boiling *** flow pattern of the pseudo-phases in the dia-Widom process contains single-phase flow,steady pseudo-film flow,unsteady pseudo-film flow,partial pseudo-bubbles flow and flocculent pseudo-film ***-bubbles have similar behaviors to subcritical bubbles,i.e.,break-up,deformation,condensation and *** researches in this work are favorable for understanding the heat transfer mechanism of supercritical fluids during flow transition.

关键词： supercritical heat transfer large eddy simulation transition pseudo-boiling

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Experimental and numerical study on protective effect of RC blast wall against air shock wave

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Defence Technology（防务技术） 2024年第1期31卷 567-579页

作者： xin-zhe Nian Quan-min Xie xin-li Kong Ying-kang Yao Kui Huang State Key Laboratory of Precision Blasting Jianghan UniversityWuhan430056China Hubei Key Laboratory of Blasting Engineering Jianghan UniversityWuhan430056China Hubei(Wuhan)Institute of Explosion and Blasting Technology Jianghan UniversityWuhan430056China College of Defense Engineering Army Engineering University of PLANanjing210007China Institute of Defense Engineering AMSPLALuoyang471023China

Prototype experiments were carried out on the explosion-proof performance of the RC blast *** mass of TNT detonated in the experiments is 5 kg and 20 kg *** shock wave overpressure was tested in different *** above experiments were numerically simulated,and the simulated shock wave overpressure waveforms were compared with that tested and given by CONWEP *** results show that the numerically simulated waveform is slightly different from the test waveform,but similar to CONWEP *** dimensional analysis and numerical simulation under different working conditions,the equation for the attenuation rate of the diffraction overpressure behind the blast wall was *** to the corresponding standards,the degree of casualties and the damage degree of the brick concrete building at a certain distance behind the wall can be determined when parameters are *** above results can provide a reference for the design and construction of the reinforced concrete blast wall.

关键词： Blast wall Shock wave Diffraction Overpressure Protection

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Atomistic understanding of rough surface on the interfacial friction behavior during the chemical mechanical polishing process of diamond

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Friction 2024年第6期12卷 1119-1132页

作者： Song yuan Xiaoguang GUO Hao WANG Renke kang Shang GAO State Key Laboratory of High-performance Precision Manufacturing Dalian University of TechnologyDalian 116024China

The roughness of the contact surface exerts a vital role in *** is still a significant challenge to understand the microscopic contact of the rough surface at the atomic ***,the rough surface with a special root mean square(RMS)value is constructed by multivariate Weierstrass–Mandelbrot(W–M)function and the rubbing process during that the chemical mechanical polishing(CMP)process of diamond is mimicked utilizing the reactive force field molecular dynamics(ReaxFF MD)*** is found that the contact area A/A0 is positively related with the load,and the friction force F depends on the number of interfacial bridge *** the surface roughness will increase the friction force and friction *** model with low roughness and high lubrication has less friction force,and the presence of polishing liquid molecules can decrease the friction force and friction *** RMS value and the degree of damage show a functional relationship with the applied load and lubrication,i.e.,the RMS value decreases more under larger load and higher lubrication,and the diamond substrate occurs severer damage under larger load and lower *** work will generate fresh insight into the understanding of the microscopic contact of the rough surface at the atomic level.

关键词： diamond random roughness reactive force field molecular dynamics(ReaxFF MD) friction Weierstrass-Mandelbrot(W-M)function chemical mechanical polishing(CMP)

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Optimization of Gas Production from Hydrate-Bearing Sediments with Fluctuation Characteristics

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Journal of Ocean University of China 2024年第3期23卷 618-632页

作者： LI Yaobin XU Tianfu xin xin YU Han yuan Yilong ZHU Huixing Key Laboratory of Groundwater Resources and Environment Ministry of EducationJilin UniversityChangchun 130021China Jilin Provincial Key Laboratory of Water Resources and Environment Jilin UniversityChangchun 130021China

As an important source of low-carbon,clean fossil energy,natural gas hydrate plays an important role in improving the global energy consumption *** the hydrate industry in the South China Sea is important to achieving‘carbon peak and carbon neutrality’goals as soon as ***-water areas subjected to the action of long-term stress and tectonic movement have developed complex and volatile terrains,and as such,the morphologies of hydrate-bearing sediments(HBSs)fluctuate *** key to numerically simulating HBS morphologies is the establishment of the conceptual model,which represents the objective and real description of the actual geological ***,current numerical simulation models have characterized HBSs into horizontal strata without considering the fluctuation *** representing the HBS as a horizontal element reduces simulation ***,the commonly used horizontal HBS model and a model considering the HBS’s fluctuation characteristics with the data of the SH2 site in the Shenhu Sea area were first constructed in this ***,their production behaviors were compared,and the huge impact of the fluctuation characteristics on HBS production was *** this basis,the key parameters affecting the depressurization production of the fluctuating HBSs were studied and *** research results show that the fluctuation characteristics have an obvious influence on the hydrate production of HBSs by affecting their temperatures and pressure distributions,as well as the transmission of the pressure drop and methane gas ***,the results show that the gas productivity of fluctuating HBSs was about 5%less than that of horizontal *** optimizing the depressurization amplitude,well length,and layout location of vertical wells,the productivity of fluctuating HBSs increased by about 56.6%.

关键词： natural gas hydrate numerical simulation fluctuation characteristics depressurization production production well optimization

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Hydrogen-rich surface of MoC catalysts for efficient CO_(2) hydrogenation induced by a coupled hydrogen donator

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Nano Research 2024年第8期17卷 7762-7767页

作者： Dong Xu Si-yuan Xia Qi-yuan Li Jie-Sheng Chen xin-Hao Li School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative MoleculesShanghai Jiao Tong UniversityShanghai 200240China

Direct CO_(2) hydrogenation offers an important strategy for promoting the global carbon balance,but high thermodynamic and kinetic stability of CO_(2) has restricted its applicability to only a handful of industrial ***,we introduce a proof-of-concept application of the electron-rich Pt surface to promote hydrogen donation for electron-rich MoC particles acting as hydrogen acceptors,thereby constructing hydrogen-rich surface of MoC active ***,the formed hydrogen-rich and electronrich surface could greatly decrease reaction activation energy to boost the efficient CO_(2) hydrogenation into formic acid over the MoC *** optimized MoC@NC/Pt-0.1(NC:nitrogen-doped carbon)catalyst exhibits a high turnover frequency(TOF)value of 1.2 h^(−1) at a lower temperature of 60℃and a TOF of 24.2 h^(−1) under standard reaction conditions widely used in the literature,exceeding 7 times of MoC@NC catalyst and surpassing the benchmark classical non-noble metal active center-based heterogeneous catalyst.

关键词： electron-rich Pt nanoparticles hydrogen donation hydrogen-rich MoC nanoparticles CO_(2) hydrogenation formic acid

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Adaptive security control of time-varying constraints nonlinear cyber-physical systems with false data injection attacks

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Journal of Control and Decision 2024年第1期11卷 50-59页

作者： Yue-Ming Wang yuan-xin Li Department of Science Liaoning University of TechnologyJinzhouPeople’s Republic of China

In this article,an adaptive security control scheme is presented for cyber-physical systems(CPSs)suffering from false data injection(FDI)attacks and time-varying state ***,an adaptive bound estimation mechanism is introduced in the backstepping control design to mitigate the effect of FDI ***,to solve the unknown sign time-varying statefeedback gains aroused by the FDI attacks,a type of Nussbaum function is employed in the adaptive security ***,by constructing a barrier Lyapunov function,it can be ensured that all signals of controlled system are bounded and the time-varying state constraints are not ***,the provided simulation examples demonstrate the effectiveness of the proposed controller.

关键词： Neural networks backstepping technology false data injection(FDI)attacks nonlinear cyber-physical systems controls

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