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Prediction model of end-point phosphorus content for BOF based on monotone-constrained BP neural network

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Journal of Iron and Steel Research International 2022年第5期29卷 751-760页

作者： Kai-xiao Zhou Wen-hui Lin Jian-kun Sun Jiang-shan Zhang De-zheng Zhang xiao-ming feng Qing Liu State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing100083China School of Computer and Communication Engineering University of Science and Technology BeijingBeijing100083China Xinyu Iron and Steel Co. Ltd.Xinyu338001JiangxiChina

Dephosphorization is essential content in the steelmaking process,and the process after the converter has no dephosphorization ***,phosphorus must be removed to the required level in the converter *** order to better control the end-point phosphorus content of basic oxygen furnace(BOF),a prediction model of end-point phosphorus content for BOF based on monotone-constrained backpropagation(BP)neural network was *** the theoretical analysis of the dephosphorization process,ten factors that affect the end-point phosphorus content were determined as the input variables of the *** correlations between influencing factors and end-point phosphorus content were determined as the constraint condition of the model.200 sets of data were used to verify the accuracy of the model,and the hit ratios in the range of±0.005%and±0.003%are 94%and 74%,*** fit coefficient of determination of the predicted value and the actual value is 0.8456,and the root-mean-square error is 0.0030;the predictive accuracy is better than that of ordinary BP neural network,and this model has good *** can provide useful reference for real production and also provide a new approach for metallurgical predictive modeling.

关键词： Converter End-point phosphorus content Monotonic constraint BP neural network Prediction model Steelmaking

Gene expression profile analyses of mice livers injured by Leigongteng

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World Journal of Gastroenterology 2007年第26期13卷 3619-3624页

作者： Yong Chen, xiao-ming Zhang feng-Mei Han Peng Du Qi-Song Xia Hubei Provincial Key Laboratory of Traditional Chinese Medicine & Biotechnology School of Life Science Hubei University Wuhan 430062 Hubei Province China

AIM： To analyze the gene expression profiles of mice livers injured by Leigongteng and explore the relationship between the differentially expressed genes and liver damage. METHODS： The experimental mice were randomly divided into a control group and a liver-injured group in which the mice were administrated 33 μγ, of triptolide/ kg per day for 30 d. Liver mRNAs were extracted from animals in both groups and were reverse-transcribed to cDNA with dUTP labeled by different fluorescence （Cy3, Cy5） as hybridization probes. The mixed probes were hybridized with oligonucleotide microarray chips. The fluorescent signal results were acquired by scanner and analyzed with software. RESULTS： Among the 35852 target genes, 29 genes were found to be significantly differentially expressed, with 20 genes up-regulated and 9 genes down-regulated. The reliability of the differentially expressed genes was validated by RT-PCR experiments of 5 randomly selected differentially expressed genes. CONCLUSION： Based on the biological functions of the differentially expressed genes, it is obvious that the occurrence and development of liver damage induced by Leigongteng in mice are highly associated with immune response, metabolism, apoptosis and the cell skeleton of liver cells. This might be important for elucidating the regulatory network of gene expression associated with liver damage and it may also be important for discovering the pathogenic mechanisms of liver damage induced by Leigongteng.

关键词： Tripterygium Wilfordii Hook.f. Gene expre-ssion profile Oligonucleotide microarray Mice

A new method for concentration analysis of bacterial endotoxins in perfluorocarbon

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Frontiers of Materials Science 2014年第4期8卷 399-402页

作者： Dan-Dan CHEN xiao-ming feng Chun-Ren WANG Qing-Quan HUANG Zhao-Peng YANG Qing-Yuan MENG National Institutes for Food and Druq Control Beijing 100050 China School of Materials Science and Engineering Tsinghua University Beijing 100084 China

This communication demonstrates the feasibility of the gel-clot method for the analysis of bacterial endotoxins in water extracts of perfluorocarbon which is a water insoluble liquid medical device. Perfluorocarbon （10 mL） was shaken with 10 mL water for 15 min at 2000 r/min and the endotoxin present was extracted to the aqueous phase without interference inhibition/enhancement of the product and the recovery of endotoxin added to perfluorocarbon was determined, A validation study confirmed that endotoxins presented in perfluorocarbon pass over into the aqueous phase at concentrations of 20, 10 and 5EU/mL with recoveries from 86.8% to 96.8%. Therefore, the gel-clot test is suitable for detecting bacterial endotoxins in perfluorocarbon which is a water insoluble medical device.

关键词： perfluorocarbon bacterial endotoxin endotoxin recovery

Synthesis of 3-Substituted-6-(2,4-Dichlorophenyl)-s-Triazolo[3.4-b]-1,3,4-Oxadiazoles

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Chinese Chemical Letters 1997年第12期8卷 0-0,0-0页

作者： xiao ming feng Xun HE Yao Zhong JIANG(Union Laboratory of Asymmetric Synthcsis, Chengdu Institute of Orgnic ChemistryChinesc Academy of Sciences, Chengdu 610041) Union Lab. of Asymmetric Synthesis Chengdu Inst. of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 China

Fourteen new 2-acylhydrazino-5 -(2,4-dichlorophenyl)-1, 3,4 -oxadiazo les were prepared by nucleophilic displacement of acylhpeine at the 2-position of 2-methylsulfonyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole. Fourteen new 3-substhad-6-(2,4-dichlorophenyl)-s-triazolo [3,4-b]-1,3,4-oxadiazoles were obtained by treating 2 -acylhydrazion- 5-(2,4-dichlorophenyl )- 1, 3,4-oxadiazoles with K2CO3 solution. All the new compounds showed significant antibacterial activity

关键词： Cl Chen Dichlorophenyl Oxadiazoles Synthesis of 3-Substituted-6 s-Triazolo[3.4-b

Chilling Tolerance of Cucumber During Germination is Related to Expression of Lysine Decarboxylase Gene

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Agricultural Sciences in China 2005年第12期4卷 898-902页

作者： LU ming-hui LI xiao-ming CHEN Jin-feng CHEN Long-zheng QIAN Chun-tao National Key Laboratory of Crop Genetics and Germplasm Enhancement College of Horticulture Nanjing Agricultural UniversityNanjing 210095 P.R.China

Using cDNA-AFLP technique, a specific fragment was isolated from cucumber cultivar Changchun mici possessing chilling tolerance induced at low temperature （15℃）. This fragment, named cctr 132, could not be induced in the chilling sensitive cucumber cultivar Beijing jietou. After recovering the fragment, sequencing and translating, the results of blastx and blastp in GenBank of NCBI indicated that CCTR132 had 88.37% identities and 100% positives with Oryza sativa putative lysine decarboxylase-like protein respectively, and PGGXGTXXE, the putative conserved domain of lysine decarboxylase family, was detected from CCTR132, suggesting the cucumber chilling tolerance during germination is related to the expression of the lysine decarboxylase gene.

关键词： Cucumber Chilling tolerance cDNA-AFLP Lysine decarboxylase Cadaverine

Shortened duration and reduced area of frozen soil in the Northern Hemisphere

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The Innovation 2021年第3期2卷 109-117页

作者： Ting Li Yong-Zhe Chen Li-Jian Han Lin-Hai Cheng Yi-He Lv Bo-Jie Fu xiao-ming feng Xing Wu State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Earth Surface Processes and Resource Ecology Faculty of Geographical ScienceBeijing Normal UniversityBeijing 100875China

The changes in near-surface soil freeze-thaw cycles(FTCs)are crucial to understanding the related hydrological and biological processes in terrestrial ecosystems under a changing ***,long-term dynamics of soil FTCs at the hemisphere scale and the underlying mechanisms are not well *** this study,the spatiotemporal patterns and main driving factors of soil FTCs across the Northern Hemisphere(NH)during 1979–2017 were analyzed using multisource data fusion and attribution *** results showed that the duration and the annual mean area of frozen soil in the NH decreased significantly at rates of 0.13±0.04 days/year and 4.93104 km^(2)/year,respectively,over the past 40 *** were mainly because the date of frozen soil onset was significantly delayed by 0.1±0.02 days/year,while the end of freezing and onset of thawing were substantially advanced by 0.21±0.02 and 0.15±0.03 days/year,***,the interannual FTC changes were more drastic in Eurasia than in North America,especially at mid-latitudes(30–45N)and in Arctic regions(>75N).More importantly,our results highlighted that near-surface air temperature(Ta)and snowpack are the main driving factors of the spatiotemporal variations in soil ***,our results suggested that the long-term dynamics of soil FTCs at the hemisphere scale should be considered in terrestrial biosphere models to reduce uncertainties in future simulations.

关键词： freeze-thaw cycles frozen duration air temperature snow water equivalent soil moisture

Syntheses of (3-Benzyl-4-Aroyl-1,2,4-Triazole-5-yl)[5-(3,4,5-Trimethoxylphenyl)-1,3,4-Oxadizole-2-yl] Sulfides

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Chinese Chemical Letters 1997年第3期8卷 195-198页

作者： xiao ming feng Rong CHEN Lian Fu TANG and Yao Zhong JIANG (Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041) (To whom correspondence should be addressed ) Chengdu Inst. of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 China

Twelve new (3-benzyl-4-aroyl-1,2,4-triazole-5-yl)[5-(3,4,5-trimethoxyphenyl)-1,3,4- oxadiazole-2-yl]sulfides(2) have been synthesized from the nucleophilic displacements of 3-benzyl-4- trimethoxyphenyl)-1,3,4-oxadiazole(1). Compounds(2) were screened for their antibacterial activity against *** at 0.01%. The results show that some compounds(2) have strong inhibiting effects

关键词： Chen Zhang Syntheses of Benzyl-4-Aroyl-1,2,4-Triazole-5-yl Oxadizole-2-yl Sulfides Trimethoxylphenyl

High-dense nanocrystalline W-based alloy prepared by hot isostatic pressing with uniform microstructure, ultrahigh hardness and good thermal stability

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Tungsten 2025年第1期7卷 120-136页

作者： Zao-ming Wu Lin He Lin-Sen Ye xiao-feng Yang Jia-Jia Zhang Hong-Bo Lei Institute of Materials China Academy of Engineering Physics

High-density uniform microstructure nanocrystalline W-10wt.% Cr-5wt.% Y（W-10Cr-5Y） alloy with an average grain size of 85 nm and a relative density of 99.8% was successfully prepared.W-Cr-Y alloys with different amounts of second-phase particles were prepared by high-energy ball milling and hot isostatic pressing *** effects of composition design,ball milling parameters,and sintering parameters on the microstructure of W-Cr-Y alloys were studied.A feasible technology for controlling the synthesis of high-density nanocrystalline W-based alloys has been *** microstructure analysis of nanocrystalline W-10Cr-5Y alloy shows that there are two types of doping in the second phase:intergranular doping and intragranular *** "uniform distribution YOx-rich particles" effectively suppresses the grain growth of W and leads to the formation of nanocrystalline W-10Cr-5Y alloy.W-10Cr-5Y has an ultra-high hardness,with a Vickers hardness of 1312±12 kgf·***-temperature annealing treatment shows that W-10Cr-5Y has good thermal stability at 1000 and1100℃,as demonstrated by the comparison of Vickers hardness and grain size between annealed and unannealed alloys.

关键词： Hot isostatic pressing Microstructure Nanocrystalline tungsten Thermal stability Vickers hardness

Resolution of Spiro[4.4]nonane-1,6-dione by Chiral Inclusion Complexation

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Chinese Chemical Letters 1999年第7期10卷 559-562页

作者： xiao ming feng De Chao ZENG Zhi Li Yao Zhong JIANG(Union Laboratory of Asymmetric Synthesis. Chengdu Institute of Organic Chemistry.)(Chinese Academy of Sciences. Chengdu 610041) Union Lab. of Asymmetric Synthesis Chengdu Inst. of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 China

The racemic spiro[4.4]nonane-1,6-dione was efficiently resolved through an enantioselective inclusion complexation using chiral host BINOL by simple recrystallization with 31 .9～38.4% yield and 1000%ee.

关键词： Resolution chiral inclusion complexation enantioselectivity