Synthesis of 3-Substituted-6-(2,4-Dichlorophenyl)-s-Triazolo[3.4-b]-1,3,4-Oxadiazoles

作     者：Xiao Ming FENG Xun HE Yao Zhong JIANG(Union Laboratory of Asymmetric Synthcsis, Chengdu Institute of Orgnic ChemistryChinesc Academy of Sciences, Chengdu 610041) 

作者机构：Chinese Acad Sci Chengdu Inst Organ Chem Union Lab Asymmetr Synth Chengdu 610041 Peoples R China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：1997年第8卷第12期

页      面：0-0,0-0页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

主　　题：Cl Chen Dichlorophenyl Oxadiazoles Synthesis of 3-Substituted-6 s-Triazolo[3.4-b 

摘      要：Fourteen new 2-acylhydrazino-5 -(2,4-dichlorophenyl)-1, 3,4 -oxadiazo les were prepared by nucleophilic displacement of acylhpeine at the 2-position of 2-methylsulfonyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole. Fourteen new 3-substhad-6-(2,4-dichlorophenyl)-s-triazolo [3,4-b]-1,3,4-oxadiazoles were obtained by treating 2 -acylhydrazion- 5-(2,4-dichlorophenyl )- 1, 3,4-oxadiazoles with K2CO3 solution. All the new compounds showed significant antibacterial activity