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Method for determining the position of landslide slip-surface with a typical inclinometric curves

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Journal of Mountain Science 2024年第2期21卷 413-432页

作者： chen Hao WU hong-gang Ocean College Zhejiang UniversityZhoushan 316000China China Northwest Research Institute Co.Ltd.of CREC Lanzhou 730070China

In the actual monitoring of deep hole displacement,the identification of slip surfaces is primarily based on abrupt changes observed in the inclinometric *** conventional identification methods,inclinometric curves exhibiting indications of sliding can be categorized into three types:B-type,D-type,and *** position of the slip surface is typically determined by identifying the depth corresponding to the point of maximum displacement ***,this method is sensitive to the interval of measurement points and the observation scale of the coordinate axes and suffers from unclear sliding surfaces and uncertain *** on the variation characteristics of these diagonal curves,we classified the landslide into three components:the sliding body,the sliding interval,and the immobile ***,three different generalization models were established to analyze the relationships between the curve form and the slip surface location based on different physical indicators such as displacement rate,relative displacement,and *** results show that the displacement rate curves of an r-type slope exhibit a clustering feature in the sliding interval,and by solving for the depth of discrete points within the step phase,it is possible to determine the location of the slip *** the other hand,D-type slopes have inflection points in the relative displacement curve located at the slip *** acceleration curves of B-type slopes exhibit clustering characteristics during the sliding interval,while the scattered acceleration data demonstrate wandering ***,the slip surface location can be revealed by solving the depth corresponding to the maximum acceleration with cubic spline *** approach proposed in this paper was applied to the monitoring data of a landslide in Yunnan Province,*** results indicate that our approach can accurately identify the slip surface location and enable computability of its po

关键词： Inclinometric curve Slip-surface position Displacement rate Relative displacement Acceleration

Triboelectric nanogenerators for self-powered neurostimulation

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Nano Research 2024年第10期17卷 8926-8941页

作者： Shumao Xu Farid Manshaii xiao xiao Junyi Yin Jun chen Department of Bioengineering University of CaliforniaLos AngelesLos AngelesCA 90095USA

The burgeoning field of soft bioelectronics heralds a new dawn in medical treatment for neurological and psychiatric conditions,presenting innovative methods for the stimulation,inhibition,and precise sensing of neuronal *** to these advancements is the challenge of power supply;devices dependent on traditional batteries face limitations regarding miniaturization and require invasive surgeries for battery *** nanogenerators(TENGs),which generate power from biomechanical movements,offer a promising solution for developing self-powered neurostimulation devices without the need for an external power *** review delves into recent progress in TENGs,with a focus on their application in selfpowered neurostimulation *** utility of TENGs across various nervous systems—including the center,autonomic,and somatic nervous systems—is explored and presented,highlighting the potential for these devices to facilitate neurological *** summarizing TENGs’operational details and the potential for clinical translation,this review also identifies challenges associated with the implantation and integration of neural electrodes and presents recent advances in solutions,aiming to reshape electric treatments for neurological diseases.

关键词： triboelectric nanogenerators neurostimulation self-powered soft bioelectronics biomechanical energy harvesting

Isotopic characteristics and source analysis of atmospheric ammonia during agricultural periods in the Xichuan area of the Danjiangkou Reservoir

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Journal of Environmental Sciences 2024年第2期136卷 460-469页

作者： xiaoshu chen Tongqian Zhao Chunyan xiao xiaoming Guo Feihong chen Institute of Resources and Environment Henan Polytechnic UniversityJiaozuo 454000China

Nitrogen deposition is an important means of exogenous nitrogen input in reservoir *** activities around the reservoir lead to a sharp increase in the concentration of ammonia in the atmosphere,which poses a threat to the reservoir water *** the contribution of agricultural ammonia release to atmospheric NH_(x)(gaseous NH_(3)and particulate NH_(4)^(+)),in the reservoir area can provide a theoretical foundation for local reactive nitrogen *** collected atmospheric NH_(3)and NH_(4)^(+)samples during the agricultural periods and analyzed the isotopic characteristics of atmospheric NH_(x)and the contribution rates of different ammonia sources in the Xichuan area of the Danjiangkou *** results showed that the initialδ~(15)N values of NH_(3)(-30.0‰to–7.2‰)and particulate NH_(4)^(+)(–33‰to+4.9‰for finer and coarser particles,respectively)are different,and their contribution ratios from dissimilar ammonia sources are also different,among which NH_(4)^(+)is more susceptible to meteorological ***,since the atmospheric NH_(x)in the Xichuan area is mainly gaseous NH_(3),the final sources of atmospheric ammonia nitrogen source depend on gaseous NH_(3).Agricultural sources(59%-74%)were the main NH_(3)sources in this *** them,the fertilizer use emission was dominant;it had the highest contribution rate in summer during the agricultural period and a more prominent impact in areas with less human *** regulation of the application of high-ammonia releasing fertilizer,especially during the agricultural period in summer,is an effective way to reduce the threat of atmospheric ammonia to water health.

关键词： Danjiangkou reservoir Atmospheric ammonia nitrogen Isotope Ammonia source analysis Agricultural sources

Comparison of biliary protein spectrum in gallstone patients with obesity and those with normal body weight

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Hepatobiliary & Pancreatic Diseases International 2024年第4期23卷 385-392页

作者： Min-Zhi chen Ping Xie xiao-Chang Wu Zhen-Hua Tan Hai Qian Zhi-hong Ma Xing Yao Department of Hepatopancreatobiliary Surgery Huzhou Central HospitalAffiliated Huzhou HospitalZhejiang University School of MedicineHuzhou 313000China Huzhou Key Laboratory of Molecular Medicine Huzhou Central HospitalAffiliated Huzhou HospitalZhejiang University School of MedicineHuzhou 313000China

Background: Obesity is a common public health issue and is currently deemed a disease. Research has shown that the risk of gallstones in individuals with obesity is elevated. This study aimed to explore the bile proteomics differences between cholelithiasis patients with obesity and normal body weight. Methods: Bile samples from 20 patients(10 with obesity and 10 with normal body weight) who underwent laparoscopic cholecystectomy at our center were subjected to tandem mass tag labeling(TMT) and liquid chromatography-tandem mass spectrometry(LC-MS/MS), followed by further bioinformatic analysis. Results: Among the differentially expressed proteins, 23 were upregulated and 67 were downregulated. Bioinformatic analysis indicated that these differentially expressed proteins were mainly involved in cell development, inflammatory responses, glycerolipid metabolic processes, and protein activation cascades. In addition, the activity of the peroxisome proliferator-activated receptor(PPAR, a subfamily of nuclear receptors) signaling pathway was decreased in the Kyoto Encyclopedia of Genes and Genomes(KEGG) enrichment analysis. Two downregulated proteins in the PPAR signaling pathway, APO A-Ⅰ and APO A-Ⅱ, were confirmed using enzyme-linked immunosorbent assay. Conclusions: The PPAR signaling pathway may play a crucial role in the development of cholelithiasis among patients with obesity. Furthermore, biliary proteomics profiling of gallstones patients with obesity is revealed, providing a reference for future research.

关键词： Proteome profiling Gallstones Obesity-associated gallstones Tandem mass tag labeling PPAR signaling

Endoscopic-ultrasound-guided biliary drainage with placement of electrocautery-enhanced lumen-apposing metal stent for palliation of malignant biliary obstruction:Updated meta-analysis

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 907-920页

作者： Zu-Xiang Peng Fang-Fang chen Wen Tang Xu Zeng hong-Juan Du Ru-Xian Pi hong-Ming Liu xiao-xiao Lu Department of Hepatobiliary Surgery Daping HospitalArmy Medical UniversityChongqing 400042China Department of Oncology Chongqing General HospitalChongqing UniversityChongqing 401147China Department of Gastroenterology and Hepatobiliary Surgery People’s Hospital of Fenggang CountyGuizhou 564200Guizhou ProvinceChina Hepatobiliary and Pancreatic Tumor Center Chongqing University Cancer HospitalChongqing 400030China

BACKGROUND Endoscopic ultrasound-guided biliary drainage using electrocautery-enhanced(ECE)delivery of lumen-apposing metal stent(LAMS)is gradually being re-cognized as a viable palliative technique for malignant biliary obstruction after endoscopic retrograde cholangiopancreatography(ERCP)***,most of the studies that have assessed its efficacy and safety were small and *** meta-analyses of six or fewer studies that were published 2 years ago were therefore underpowered to yield convincing *** To update the efficacy and safety of ECE-LAMS for treatment of biliary ob-struction after ERCP *** We searched PubMed,EMBASE,and Scopus databases from the inception of the ECE technique to May 13,*** outcome measure was pooled technical success rate,and secondary outcomes were pooled rates of clinical success,re-intervention,and adverse ***-analysis was performed using a random-effects model following Freeman-Tukey double-arcsine transformation in R soft-ware(version 4.1.3).RESULTS Fourteen eligible studies involving 620 participants were ultimately *** pooled rate of technical success was 96.7%,and clinical success was 91.0%.Adverse events were reported in 17.5%of *** reinter-vention rate was 7.3%.Subgroup analyses showed results were generally *** ECE-LAMS has favorable success with acceptable adverse events in relieving biliary obstruction when ERCP is *** consistency of results across most subgroups suggested that this is a generalizable approach.

关键词： Biliary obstruction Biliary drainage Electrocautery-enhanced lumen-apposing metal stents Endoscopic ultrasound Endoscopic retrograde cholangiopancreatography failure

Regioselective cation exchange reaction for photoelectrochemical water splitting

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Rare Metals 2024年第7期43卷 3400-3407页

作者： Mo-Yan chen Tai-Song Zhang Zhi Yan Jiang-Nan Lv xiao-Ting Sun Rui-Xia Yang Mark TSwihart xiao-hong Xu Yang Liu Research Institute of Materials Science of Shanxi Normal University&Key Laboratory of Magnetic Molecules and Magnetic Information Materials of Ministry of Education Taiyuan 030031China Department of Chemical and Biological Engineering University at Buffalo(SUNY)NY 14260USA Department of Materials Science Fudan UniversityShanghai 200433China

Engineering copper sulfide-based heterostructures via cation exchange(CE)is an appealing approach,as it allows selective combination of distinct compositions and functions of metal *** heterostructures can play a significant role in photoelectrochemical applications,but the effect of the ratio between two or more domains in such heterostructures on the photoresponse has not been well explored.

关键词： exchange sulfide splitting

Progress on Bionic Textured Cutting Tools:A Review and Prospects

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Journal of Bionic Engineering 2024年第1期21卷 19-55页

作者： hong Wei Guangjun chen Zhuang chen Zhiwei Yu Jiashuai Huang Tianjin Key Laboratory of High Speed Cutting and Precision Processing Tianjin 300222China School of Mechanical Engineering Tianjin University of Technology and EducationTianjin 300222China

Cutting tools are known as the“productivity”of the manufacturing industry,which affects the production efficiency and quality of the workpiece,and has become the focus of research and attention in academia and ***,traditional cutting tools often suffer from adhesion or wear during the cutting process,which considerably reduces the cutting efficiency and service life of the tools,and makes it difficult to meet current production *** solve the above problems,scholars have introduced bionics into the tool’s design,applying the microscopic structure of the biological surface to the tool surface to alleviate the tool’s *** paper mainly summarizes the research progress of bionic textured cutting ***,categorize whether the bionic texture design is inspired by a single organism or multiple ***,it is discussed that the non-smooth surface of the biological surface has five characteristics:hydrophilic lubricity,wear resistance,drag reduction and hydrophobicity,anti-adhesion,and arrangement,and the non-smooth structure of these different characteristics are applied to the surface of the tool is designed with bionic ***,the cutting performance of bionic textured cutting tools is *** anti-friction and wear-resisting mechanism of bionic textured cutting tools is ***,some pending problems and perspectives have been proposed to provide new inspirations for the design of bionic textured cutting tools.

关键词： Bionic textured cutting tools Biological microstructure characteristics Cutting performance Anti-friction and wear-resisting mechanism

Publication trends of Leber congenital amaurosis researches:a bibliometric study during 2002-2022

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International Journal of Ophthalmology(English edition) 2024年第8期17卷 1501-1509页

作者： xiao-Xu Huang Yi-Min Wang Min-Yue Xie Yi-Qing Sun xiao-Huan Zhao Yu-hong chen Jie-Qiong chen Si-Yang Han Min-Wen Zhou xiao-Dong Sun Department of Ophthalmology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China National Clinical Research Center for Eye Disease Shanghai 200080China Shanghai Key Laboratory of Ocular Fundus Diseases Shanghai 200080China Shanghai Engineering Center for Visual Science and Photomedicine Shanghai 200080China Department of Ophthalmology Zhongshan HospitalFudan UniversityShanghai 200030China Beijing Tongren Hospital Capital Medical UniversityBeijing 100054China Eberly College of Science Penn State UniversityUniversity Park 16802-1503United States

AIM:To analyze the changes in scientific output relating to Leber congenital amaurosis(LCA)and forecast the study trends in this ***:All of the publications in the field of LCA from 2002 to 2022 were collected from Web of Science(WOS)*** analyzed the quantity(number of publications),quality(citation and H-index)and development trends(relative research interest,RRI)of published LCA research over the last two ***,VOSviewer software was applied to define the co-occurrence network of keywords in this ***:A total of 2158 publications were ultimately *** found that the focus on LCA kept rising and peaked in 2015 and 2018,which is consistent with the development trend of gene *** USA has contributed most to this field with 1162 publications,56674 citations and the highest H-index value(116).The keywords analysis was divided into five clusters to show the hotspots in the field of LCA,namely mechanism-related,genotype-related,local phenotype-related,system phenotype-related,and *** also identified gene therapy and antiretinal degeneration therapy as a major focus in recent ***:Our study illustrates historical research process and future development trends in LCA *** may help to guide the orientation for further clinical diagnosis,treatment and scientific research.

关键词： VOSviewer bibliometrics Leber congenital amaurosis gene therapy hotpots

The acceptance of traditional Chinese medicine among patients with Parkinson's disease:A hospital survey

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Journal of Integrative Medicine 2024年第2期22卷 180-187页

作者： Peng Wang Jing hong Zhu-qian Tang Bi-zhen Gong xiao-rong Qi Han Jiang Bo Pan Qi chen Postgraduate School Medical School of Chinese People’s Liberation ArmyBeijing 100853China Senior Department of Traditional Chinese Medicine the Sixth Medical Center of PLA General HospitalBeijing 100853China Department of Integration of Chinese and Western Medicine School of Basic Medical SciencesPeking UniversityBeijing 100191China Department of Integrative Oncology the First Affiliated Hospital of Naval Medical UniversityShanghai 200433China School of Traditional Chinese Medicine Naval Medical UniversityShanghai 200433China School of Pharmacy Nanjing University of Chinese MedicineNanjing 210023Jiangsu ProvinceChina Department of Dermatology the First Clinical Medical CollegeAnhui University of Chinese MedicineHefei 230012Anhui ProvinceChina

Objective:The efficacy of medications for Parkinson’s disease(PD)tend to decline over time,which has a serious impact on patients’health and quality of *** some extent,traditional Chinese medicine(TCM)can resolve the distressing problem of ineffective dopaminergic medication in PD *** purpose of this study was to investigate the attitude,acceptance,and independent predictors of TCM in PD patients admitted to the outpatient department of a tertiary ***:A cross-sectional study of PD patients was conducted in the outpatient department of a large tertiary hospital in Beijing from March 2022 to June 2023.A self-report questionnaire was developed to investigate PD patients’attitudes and acceptance of TCM based on the *** logistic regression analyses were also performed to further clarify the independent predictors influencing patients’adoption of TCM ***:A total of 397 patients completed the questionnaire,of which 78.09%were willing to be treated with TCM and 21.91%indicated that they were not willing to use *** logistic regression analysis showed that several parameters were correlated with a patient’s willingness to include TCM in their therapeutic *** included education level of a bachelor’s degree(odds ratio[OR)=8.554;95%confidence interval[CI]:4.112–17.794;P<0.001,vs junior high school education),living in an urban setting(OR=8.022;95%CI:4.577–14.060;P<0.001,vs rural),having other underlying diseases(OR=5.126;95%CI:3.078–8.537;P<0.001,vs none),having previously used TCM(OR=3.083;95%CI:1.852–5.134;P<0.001,vs not used),believing that TCM therapy is safe(OR=3.530;95%CI:1.446–8.616;P=0.006,vs not thought),believing that TCM therapy is effective(OR=3.859;95%CI:1.482–10.047;P=0.006,vs not understood),and being willing to discuss ongoing TCM therapy with an attending physician(OR=62.468;95%CI:30.350–128.574;P<0.001,vs not informed).Conclusion:This study initially investigated the acceptance

关键词： Parkinson's disease Traditional Chinese medicine Cross-sectional study