Triboelectric nanogenerators for self-powered neurostimulation

作     者：Shumao Xu Farid Manshaii Xiao Xiao Junyi Yin Jun Chen 

作者机构：Department of BioengineeringUniversity of CaliforniaLos AngelesLos AngelesCA 90095USA 

出 版 物：《Nano Research》 (纳米研究（英文版）)

年 卷 期：2024年第17卷第10期

页      面：8926-8941页

核心收录：

学科分类：080801[工学-电机与电器] 0808[工学-电气工程] 08[工学] 

基　　金：the Vernroy Makoto Watanabe Excellence in Research Award at the UCLA Samueli School of Engineering,the Office of Naval Research Young Investigator Award(No.N00014-24-1-2065) NIH Grant(No.R01 CA287326) the American Heart Association for the Innovative Project Award(No.23IPA1054908) Transformational Project Award(No.23TPA1141360) Second Century Early Faculty Independence Award(No.23SCEFIA1157587) the Brain&Behavior Research Foundation Young Investigator Grant(No.30944) the NIH National Center for Advancing Translational Science UCLA CTSI(No.KL2TR001882) 

主　　题：triboelectric nanogenerators neurostimulation self-powered soft bioelectronics biomechanical energy harvesting 

摘      要：The burgeoning field of soft bioelectronics heralds a new dawn in medical treatment for neurological and psychiatric conditions,presenting innovative methods for the stimulation,inhibition,and precise sensing of neuronal *** to these advancements is the challenge of power supply;devices dependent on traditional batteries face limitations regarding miniaturization and require invasive surgeries for battery *** nanogenerators(TENGs),which generate power from biomechanical movements,offer a promising solution for developing self-powered neurostimulation devices without the need for an external power *** review delves into recent progress in TENGs,with a focus on their application in selfpowered neurostimulation *** utility of TENGs across various nervous systems—including the center,autonomic,and somatic nervous systems—is explored and presented,highlighting the potential for these devices to facilitate neurological *** summarizing TENGs’operational details and the potential for clinical translation,this review also identifies challenges associated with the implantation and integration of neural electrodes and presents recent advances in solutions,aiming to reshape electric treatments for neurological diseases.