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Inter-comparisons of VOC oxidation mechanisms based on box model:A focus on OH reactivity

Journal of Environmental Sciences 2022年第4期34卷 286-296页

作者： Xiaoyun Yang Bin Yuan Zhe Peng Yuwen Peng caihong wu Suxia Yang Jin Li Min Shao Institute for Environmental and Climate Research Jinan UniversityGuangzhou 511443China Guangdong-Hongkong-Macao Joint Laboratory of Collaborative Innovation for Environmental Quality Guangzhou 511443China Department of Chemistry and Cooperative Institute for Research in Environmental Sciences University of ColoradoBoulderCO 80309USA

Volatile organic compounds(VOCs)oxidation processes play a very important role in atmospheric chemistry,and the chemical reactions are expressed in various manners in chemical *** gain an improved understanding of VOCs evolution during oxidation processes and evaluate the discrepancies of VOCs oxidation schemes among different mechanisms,we used the total VOC reactivity as a diagnostic and evaluated tool to explore the differences for six widely used chemical *** compared the total VOC reactivity evolution under high-NO_(x)xconditions for several sets of precursors,including n-pentane,toluene,ethene,isoprene and a mixture of 57 Photochemical Assessment Monitoring Stations(PAMS)species in a 0-D photochemical box ***-comparison of total VOC reactivity of individual precursor simulations showed discrepancies to different extent of the oxidation schemes among the studied mechanisms,which are mainly attributed to the different lumping approaches for organic *** PAMS simulation showed smaller discrepancy than individual precursor cases in terms of total VOC ***07 and RACM2 performances are found to better match the MCM for simulation of total VOC *** suggest that the performance in simulating secondary organic products,OH concentrations and NO_(x)concentrations are related to the OH reactivity discrepancies among various chemical *** in this study can be used in selection of chemical mechanisms to better model OH reactivity in different *** results in this study also provide directions to further improve the ability in modelling total VOC reactivity with the chemical mechanisms.

关键词： VOCs Box model Chemical mechanism Total VOC reactivity VOC oxidation

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Mechanism of mitochondrial respiratory control in cas-pase-3 induced positive feed-back loop in apoptosis

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Chinese Science Bulletin 2002年第6期47卷 480-484页

作者： XIA Tian JIANG Chunsun LI Linjiang CHEN Quan wu caihong LIU Shusen National Key Lab of Biomembrane and Membrane Biotechnology Peking UniversityBeijing 100871China National Key Lab of Biomembrane and Membrane Biotechnology Institute of ZoologyChinese Academy of SciencesBeijing 100080China Tianjin Sports Institute Tianjin 300381China

Caspase-3 plays a central role in the execution of apoptosis. Besides many substrates of caspase-3, mitochondria seem to be one of the candidate targets in the apop-totic process. We evaluated the effects of caspase-3 on the isolated mitochondria in detail, and especially focused on the mechanism involved in mitochondrial functions, which were not fully assessed till now. Our results showed that re-combinant caspase-3 induced the increase of superoxide production, the dissipation of mitochondrial membrane potential and rate increasing of mitochondrial state 4 respiration. Caspases inhibitor, z-VAD-fmk can inhibit these effects of caspase-3 on mitochondria. Bcl-xL and cyclosporin A were also shown to be able to inhibit these changes. These results suggested a possible mechanism in caspase-3 induced disruption of mitochondrial membrane barrier which formed a positive feedback loop in apoptosis.

关键词： mitochondria caspase-3 ROS RCR membrane poten-tial PTP.

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Human endothelial senescence can be induced by TNF-α

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Chinese Science Bulletin 2002年第2期47卷 118-122页

作者： Jianjun Zhou Yunfei Gao Hongfang Wang Quan Chen caihong wu Meifu Feng The National Key Laboratory of Biomembrane and Membrane Biotechnology College of Life Sciences Peking University Beijing China The National Key Laboratory of Biomembrane and Membrane Biotechnology Institute of Zoology Chinese Academy of Sciences Beijing China Department of Cell Biology and Genetics College of Life Sciences Peking University Beijing China

TNF-α is one of the most important proin-flammatory cytokines in mediating multiple physio-patho-logical functions during immunological responses. Vascular endothelial cells, when stimulated by TNF-α, can increase the expression of multiple cytokines and cellular adhesion molecules and, in turn, actively promote the inflammatory responses by recruiting and activating of leukocytes to the inflammatory site. In addition to endothelial death induced by TNF-α, we found for the first time that TNF-α can also induce the human endothelial cells senescence. The induced senescent endothelial cells will display SA-B-Gal staining and they were arrested in G0-G1 phase. We found that △(?)m would always be up-regulated in response to TNF-α stimula-tion at early time but when the cells become senescent, △(?)m shows a tendency to decrease. It may reflect the sthenic func-tion of mitochondria at early time in response to TNF-α stimulation and decay when the endothelial cells were in-duced senescent. ROS

关键词： TNF-α endothelial cells inflammation senescence.

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Peroxidase from foxtail millet bran exerts anticolorectal cancer activity via targeting cellsurface GRP78 to inactivate STAT3 pathway

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Acta Pharmaceutica Sinica B 2022年第3期12卷 1254-1270页

作者： Shuhua Shan Jinping Niu Ruopeng Yin Jiangying Shi Lizhen Zhang caihong wu Hanqing Li Zhuoyu Li Institute of Biotechnology Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of EducationShanxi UniversityTaiyuan 030006China School of Life Science Shanxi UniversityTaiyuan 030006China

Molecular targeted therapy has become an emerging promising strategy in cancer treatment,and screening the agents targeting at cancer cell specific targets is very desirable for cancer *** previous study firstly found that a secretory peroxidase of class III derived from foxtail millet bran(FMBP)exhibited excellent targeting anti-colorectal cancer(CRC)activity in vivo and in vitro,whereas its underlying target remains *** highlight of present study focuses on the finding that cell surface glucose-regulated protein 78(cs GRP78)abnormally located on CRC is positively correlated with the anti-CRC effects of FMBP,indicating it serves as a potential target of FMBP against ***,we demonstrated that the combination of FMBP with the nucleotide binding domain(NBD)of cs GRP78interfered with the downstream activation of signal transducer and activator of transcription 3(STAT3)in CRC cells,thus promoting the intracellular accumulation of reactive oxygen species(ROS)and cell grown *** phenomena were further confirmed in nude mice tumor ***,our study highlights cs GRP78 acts as an underlying target of FMBP against CRC,uncovering the clinical potential of FMBP as a targeted agent for CRC in the future.

关键词： Foxtail millet bran FMBP csGRP78 STAT3 ROS Colorectal cancer

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Research on Human Body Behavior Recognition Based on Vision

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International Journal of Technology Management 2017年第2期 59-61页

作者： caihong wu wuhan Technology and Business University Wuhan Hubei Province 430065 China

This paper proposes the research on human body behavior recognition based on vision. Behavior based on high-level human structure can describe behavior more accurately, but it is dif？ cult to extract the behavioral characteristics while often relying on the accuracy of the human pose estimation. Moving object extraction of the moving targets in video analysis as the main content, research based on the image sequence robust, fast moving target extraction, motion estimation and target description algorithm, and the correlation between motion detection is to use frame, frame by comparing the difference between for change and not change area. The model is proposed based on the probability theory, and the future research will be focused on the simulation.

关键词： Human Body Behavior Recognition Computer Vision

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Application of diversified evaluation in middle school english teaching

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现代盐化工 2019年第1期46卷 149-150页

作者： wu caihong Anqing Normal University

Most of the current evaluations are for selecting and screening students, paying too much attention to students' scores and rankings, ignoring the true feedback on the students' actual learning process, not to mention incentives, regulation,and development of the student's daily study. Most schools still use the single final evaluation method of the test to evaluate students' academic performance.

关键词： formative evaluation multiple intelligences humanistic psychology

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Volatile organic compounds in wintertime North China Plain:Insights from measurements of proton transfer reaction time-of-flight mass spectrometer(PTR-ToF-MS)

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Journal of Environmental Sciences 2022年第4期34卷 98-114页

作者： Xianjun He Bin Yuan caihong wu Sihang Wang Chaomin Wang Yibo Huangfu Jipeng Qi Nan Ma Wanyun Xu Ming Wang Wentai Chen Hang Su Yafang Cheng Min Shao Institute for Environmental and Climate Research Jinan UniversityGuangzhou 511443China Guangdong-Hongkong-Macao Joint Laboratory of Collaborative Innovation for Environmental Quality Guangzhou 511443China State Key Laboratory of Severe Weather&Key Laboratory for Atmospheric Chemistry of China Meteorology Administration Chinese Academy of Meteorological SciencesBeijing 100081China Collaborative Innovation Center of Atmospheric Environment and Equipment Technology Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution ControlSchool of Environmental Science and EngineeringNanjing University of Information Science&TechnologyNanjing 210044China Nanjing Intelligent Environmental Science and Technology Co. Ltd.Nanjing 211800China Max Planck Institute for Chemistry Mainz 55128Germany

The characteristics of wintertime volatile organic compounds(VOCs)in the North China Plain(NCP)region are complicated and remain *** measurements were conducted by a proton transfer reaction time-of-flight mass spectrometer(PTR-ToF-MS)at a rural site in the NCP from November to December *** ions measured by PTRToF-MS were quantified and the overall VOC compositions were investigated by combining the measurements of PTR-ToF-MS and gas chromatography-mass spectrometer/flame ionization detector(GC-MS/FID).The measurement showed that although atmospheric VOCs concentrations are often dominated by primary emissions,the secondary formation of oxygenated VOCs(OVOCs)is non-negligible in the wintertime,i.e.,OVOCs accounts for 42%±7%in the total VOCs(151.3±75.6 ppbV).We demonstrated that PTR-MS measurements for isoprene are substantially overestimated due to the interferences of *** chemical changes of organic carbon in a pollution accumulation period were investigated,which suggests an essential role of fragmentation reactions for large,chemically reduced compounds during the heavy-polluted stage in wintertime *** changes of emission ratios of VOCs between winter 2011 and winter 2018 in the NCP support the positive effect of“coal to gas”strategies in curbing air *** high abundances of some key species(*** aromatics)indicate the strong emissions of coal combustion in wintertime of *** ratio of naphthalene to C8 aromatics was proposed as a potential indicator of the influence of coal combustion on VOCs.

关键词： North China Plain Volatile organic compound Wintertime PTR-ToF-MS

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Reflection on Core Competence of College Teachers Under the New Situation

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International English Education Research 2014年第11期 9-10页

作者： Han caihong wu Xianghua Duan Qingxiang Zhengzhou University of Science & Technology Zhengzhou Henan China 450064

＂Core competence＂ has been introduced to the field of education in the early twenty-first century and directly points to teachers. In college, teacher＇s core competence is their ability to integrate different aspects of knowledge and capacities, as well as keep continuous advantages in competitions. Core competence is the core and nature of teacher＇s professional competition. Therefore, cultivating and strengthening their core competence is the key to promote their professional development.

关键词： new situation core competence college teacher

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改革开放以来中国共产党改革话语的演进及启示

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河南社会科学 2018年第12期26卷 7-11页

作者：武彩鸿河南财经政法大学党委宣传部河南郑州450046

改革开放以来,中国共产党改革话语发生了多方位的演进。关于改革动因、改革目的、改革指导思想、改革方法、改革思维、改革纠偏以及改革成就的话语变化,是与中国共产党领导下的改革开放伟大实践息息相关的。在这些演进中,坚守四项基本... 详细信息

改革开放以来,中国共产党改革话语发生了多方位的演进。关于改革动因、改革目的、改革指导思想、改革方法、改革思维、改革纠偏以及改革成就的话语变化,是与中国共产党领导下的改革开放伟大实践息息相关的。在这些演进中,坚守四项基本原则是不变的底线,正确处理改革发展稳定的关系体现了在坚持中发展、在发展中坚持的马克思主义实践观。中国共产党改革话语的演进启示我们,构建改革话语,要坚持创新性与继承性相结合,寻求"破"和"立"之间的平衡;坚持科学性与艺术性相结合,增强话语解释力和感染力;坚持意识形态性和文化性相结合,凝聚强大中国力量;坚持针对性与系统性相结合,促进话语更加成熟。

关键词：改革开放中国共产党改革话语演进启示

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驷马山分洪道膨胀土特性及其滑坡治理

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工程勘察 2010年第2期38卷 14-18页

作者：吴彩虹安徽省水利水电勘测设计院安徽蚌埠233000

本文以安徽省滁河驷马山分洪道膨胀土为研究对象,对分洪道不同河段的膨胀土边坡进行取样,开展了膨胀土在不同工况条件下的物理力学试验。通过室内试验和现场监测,获得了膨胀土膨缩变形与土体抗剪强度变化等特征参数。经过对分洪道边坡... 详细信息

本文以安徽省滁河驷马山分洪道膨胀土为研究对象,对分洪道不同河段的膨胀土边坡进行取样,开展了膨胀土在不同工况条件下的物理力学试验。通过室内试验和现场监测,获得了膨胀土膨缩变形与土体抗剪强度变化等特征参数。经过对分洪道边坡滑动形成机理和变化规律的调查和分析,提出了膨胀土边坡稳定计算中强度取值的建议和边坡滑动的治理措施,为分洪道扩大工程及其同类工程设计提供了地质依据。

关键词：膨胀土胀缩变形边坡稳定浅层滑动

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