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Simultaneous optimization of phononic and electronic transport in two-dimensional Bi2O2Se by defect engineering

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Science China(Information Sciences) 2023年第6期66卷 87-93页

作者： Fang YAng Hong Kuan ng Jing WU Yunshan zhAO Junpeng LU School of Physics Southeast University Institute of Materials Research and Engineering Agency for ScienceTechnology and Research NNU-SULI Thermal Energy Research Center (NSTER) & Center for Quantum Transport and Thermal Energy Science (CQTES) School of Physics and TechnologyNanjing Normal University

Defect engineering represents one degree of freedom to tune the physical and chemical properties of two-dimensional (2D)***,we demonstrate that the thermal and electronic properties of 2D Bi2O2Se can be optimized simultaneously by introducing oxygen defects.2D Bi2O2Se and its oxygendeficient counterpart (Bi2Ox Se,xng oxygen defects,the thermal conductivity of 2D Bi2O2Se is reduced by nearly three times,achieving an extremely low thermal conductivity of 0.68±0.06 W/mK at room temperature via the thermal bridge *** low thermal conductivity is enabled by the scattering of phonons by targeting of high-,mid-,and low-frequency phonons due to oxygen defects,strong anharmonicity,and nanostructure boundaries,***,the mobility is also improved to 260–500 cm2·V-1·s-1and the usual polar optical phonon scattering in 2D Bi2O2Se is weakened owing to the introduction of oxygen *** results promise potential applications for thermoelectric design,nanoelectronics,and thermal barrier coating devices based on emerging 2D materials.

关键词： 2D Bi$_2$O$_2$Se thermal conductivity oxygens defects phonon scattering mobility

Ten-year review of trends in children with type 1 diabetes in England and Wales

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World Journal of Diabetes 2023年第8期14卷 1194-1201页

作者： Sze M ng Astha Soni Department of Paediatrics Mersey and West Lancashire Teaching Hospitals NHS TrustOrmskirk L392AZUnited Kingdom Department of Women's and Children's Health University of LiverpoolLiverpool L693BXMerseysideUnited Kingdom Faculty of Health Social Care&MedicineEdge Hill UniversityOrmskirk L394QPLancashireUnited Kingdom Department of Paediatrics Sheffield Children's HospitalSheffield S102THUnited Kingdom

This review describes the prevalence,incidence,and demographics of children and young people(CYP)with type 1 diabetes in England and Wales using data from the United Kingdom National Paediatric Diabetes Audit(NPDA)and has almost 100%submission from all paediatric diabetes centres *** is a powerful benchmarking tool and is an essential part of a long-term quality improvement programme for CYP with *** characteristics of this population by age,insulin regimen,complication rates,health inequalities,access to diabetes technology,socioeconomic deprivation and glycaemic outcomes over the past decade is described in the *** NPDA for England and Wales is commissioned by the United Kingdom Healthcare Quality Improvement Partnership as part of the National Clinical Audit for the United Kingdom National Service Framework for *** rising incidence of Type 1 diabetes is evidenced in the past *** in national median glycated hemoglobin for CYP with diabetes is observed over the last 10 years and the improvement sustained by various initiatives and quality improvement programmes implemented with universal health coverage.

关键词： Paediatric Type 1 Trends Outcomes Glycated hemoglobin

Master equation and runaway speed of the Francis turbine

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Journal of Hydrodynamics 2018年第2期30卷 203-217页

作者： zh.zh.ng Free Researcher Zurich Switzerland

The master equation of the Francis turbine is derived based on the combination of the angular momentum（Euler） and the energy laws. It relates the geometrical design of the impeller and the regulation settings（guide vane angle and rotational speed） to the discharge and the power output. The master equation, thus, enables the complete characteristics of a given Francis turbine to be easily computed. While applying the energy law, both the shock loss at the impeller inlet and the swirling loss at the impeller exit are taken into account. These are main losses which occur at both the partial load and the overloads and, thus, dominantly influence the characteristics of the Francis turbine. They also totally govern the discharge of the water through the impeller when the impeller is found in the standstill. The computations have been performed for the discharge, the hydraulic torque and the hydraulic efficiency. They were also compared with the available measurements on a model turbine. Excellent agreement has been achieved. The computations also enable the runaway speed of the Francis turbine and the related discharge to be determined as a function of the setting angle of the guide vanes.

关键词： Francis turbine master equation runaway speed hydraulic efficiency shock loss swirling loss streamline similarity method

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Neutrophil diversity and plasticity:Implications for organ transplantation

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Cellular & Molecular Immunology 2023年第9期20卷 993-1001页

作者： Junwen Qu Jingsi Jin Ming zh.ng Lai Guan ng Shanghai Immune Therapy Institute Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Department of Urology Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China

Neutrophils,as the first defenders against external microbes and stimuli,are highly active and finely regulated innate immune *** evidence has challenged the conventional dogma that neutrophils are a homogeneous population with a short lifespan that promotes tissue *** findings on neutrophil diversity and plasticity in homeostatic and disease states have centered on neutrophils in the *** contrast,a comprehensive understanding of tissue-specialized neutrophils in health and disease is still *** article will first discuss how multiomics advances have contributed to our understanding of neutrophil heterogeneity and diversification in resting and pathological *** discussion will be followed by a focus on the heterogeneity and role of neutrophils in solid organ transplantation and how neutrophils may contribute to transplant-related *** goal of this article is to provide an overview of the research on the involvement of neutrophils in transplantation,with the aim that this may draw attention to an underappreciated area of neutrophil research.

关键词： Neutrophil Heterogeneity Transplantation

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全膝關節置換術後硬膜外嗎啡的鎮痛效果研究

镜湖医学 2024年第1期24卷 17-19页

作者：冼東鋒吳朝興廖婧吳俊晞吳達星曹麗勤澳門鏡湖醫院麻醉科中国

目的本文對全膝關節置換術後病人硬膜外單次給予嗎啡的鎮痛效果進行了研究。方法研究資料來自澳門鏡湖醫院,2021年4月~2022年8月60例全膝關節置換手術病人隨機分到試驗組(腰硬聯合麻醉:單次蛛網膜下腔注射0.5%布比卡因2-3ml+硬膜外注射... 详细信息

目的本文對全膝關節置換術後病人硬膜外單次給予嗎啡的鎮痛效果進行了研究。方法研究資料來自澳門鏡湖醫院,2021年4月~2022年8月60例全膝關節置換手術病人隨機分到試驗組(腰硬聯合麻醉:單次蛛網膜下腔注射0.5%布比卡因2-3ml+硬膜外注射嗎啡2mg)和對照組(單次蛛網膜下腔注射0.5%布比卡因2~3ml),兩組患者術中均行關節周圍浸潤。記錄患者術後0~6h、6~12h、12~24h、24~36h、36~48h的NRS(numerical rating scale)疼痛評分以及是否發生瘙癢、尿瀦留、噁心嘔吐、呼吸抑制。結果與對照組相比,試驗組術後48小時内NRS評分≧4分發生率較低(20.0%[6/30]vs.46.7%[14/30]P=0.028),試驗組尿瀦留發生率高於對照組(36.7%[11/30]vs.6.7%[2/30]P=0.005)。結論硬膜外小劑量嗎啡可以減少全膝關節置換術後病人中至重度疼痛發生率,但病人術後尿瀦留風險增加。

关键词：硬膜外鎮痛嗎啡全膝關節置換術

Effect of perioperative branched chain amino acids supplementationin liver cancer patients undergoing surgical intervention: Asystematic review

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World Journal of Gastrointestinal Surgery 2023年第11期15卷 2596-2618页

作者： Kwan Yi Yap HongHui Chi Sherryl ng Doris HL ng Vishal G Shelat Yong Loo Lin School of Medicine National University of SingaporeSingapore 117597Singapore Department of Gastroenterology and Hepatology Tan Tock Seng HospitalSingapore 308433Singapore Lee Kong Chian School of Medicine Nanyang Technological UniversitySingapore 636921Singapore Department of General Surgery Tan Tock Seng HospitalSingapore 308433Singapore

performed independently by authors(Yap KY,Chi H,ng S)identified 50 studies for full-text ***,12 prospective RCTs and 4 non-randomised studies(1 non-randomised trial and 3 observational studies)were included.A detailed PRISMA diagram is shown in Figure *** studies included were assessed for risk of bias,with a summary of the assessment shown in Figure 2 and Table 1 for trials and non-interventional studies,*** PRISMA checklist is appended in Supplementary Figure 1.

关键词： Branched-chain amino acid Liver cancer Liver surgery Nutritional supplement Perioperative supplementation

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Journal of Hydrodynamics 2018年第1期30卷 140-152页

作者： zh.zh.ng Free Researcher Zurich Switzerland

An analytical method is presented, which enables the non-uniform velocity and pressure distributions at the impeller inlet of a pump to be accurately computed. The analyses are based on the potential flow theory and the geometrical similarity of the streamline distribution along the leading edge of the impeller blades. The method is thus called streamline similarity method（SSM）. The obtained geometrical form of the flow distribution is then simply described by the geometrical variable G（s） and the first structural constant G_Ⅰ. As clearly demonstrated and also validated by experiments, both the flow velocity and the pressure distributions at the impeller inlet are usually highly non-uniform. This knowledge is indispensible for impeller blade designs to fulfill the shockless inlet flow condition. By introducing the second structural constant G_Ⅱ, the paper also presents the simple and accurate computation of the shock loss, which occurs at the impeller inlet. The introduction of two structural constants contributes immensely to the enhancement of the computational accuracies. As further indicated, all computations presented in this paper can also be well applied to the non-uniform exit flow out of an impeller of the Francis turbine for accurately computing the related mean values.

关键词： Pumps streamline similarity method flow distribution shock loss structural constant

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Clustering Indoor Location Data for Social Distancing and Human Mobility to Combat COVID-19

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Computers, Materials & Continua 2022年第4期71卷 907-924页

作者： Yuan Ai Ho Chee Keong Tan Yin Hoe ng School of Information Technology Monash University MalaysiaJalan Lagoon SelatanBandar Sunway47500Selangor Darul EhsanMalaysia Faculty of Engineering Multimedia UniversityPersiaran MultimediaCyberjaya63100Selangor Darul EhsanMalaysia

The world is experiencing the unprecedented time of a pandemic caused by the coronavirus disease(i.e.,COVID-19).As a countermeasure,contact tracing and social distancing are essential to prevent the transmission of the virus,which can be achieved using indoor location *** on the indoor location analytics,the human mobility on a site can be monitored and planned to minimize human’s contact and enforce social distancing to contain the transmission of *** the indoor location data,the clustering can be applied to cluster spatial data,spatio-temporal data and movement behavior features for proximity detection or contact tracing *** specifically,we propose the Coherent Moving Cluster(CMC)algorithm for contact tracing,the density-based clustering(DBScan)algorithm for identification of hotspots and the trajectory clustering(TRACLUS)algorithm for clustering indoor *** feature extraction mechanism is then developed to extract useful and valuable features that can assist the proposed system to construct the network of users based on the similarity of the movement behaviors of the *** network of users is used to model an optimization problem to manage the human mobility on a *** objective function is formulated to minimize the probability of contact between the users and the optimization problem is solved using the proposed effective scheduling solution based on *** simulation results show that the proposed indoor location analytics system outperforms the existing clustering methods by about 30%in terms of accuracy of clustering *** adopting this system for human mobility management,the count of close contacts among the users within a confined area can be reduced by 80%in the scenario where all users are allowed to access the site.

关键词： Indoor location analytics COVID-19 contact tracing social distancing spatial-temporal dimensions human mobility

Unmasking metabolic dependencies in pancreatic cancer: aberrant polyamine synthesis as a promising new therapeutic target

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Signal Transduction and Targeted Therapy 2023年第11期8卷 5151-5152页

作者： Gerrit Wolters-Eisfeld Thilo Hackert Cenap Güngör Department of General Visceral and Thoracic SurgeryUniversity Medical Center Hamburg-EppendorfHamburgGermany

In a recently published Nature article,Lee et *** distinct metabolic dependencies of pancreatic ductal adenocarcinoma(PDA)cells compared to normal tissue,and discovered that PDA cells exhibited a unique reliance on de novo ornithine synthesis from glutamine,rather than *** aberrant polyamine synthesis offers a promising therapeutic target for pancreatic cancer.

关键词： synthesis den depen