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Perforated gastric ulcer causing mediastinal emphysema: A case report

World Journal of Clinical Cases 2024年第4期12卷 859-864页

作者： Zhi-Cheng Dai Xun-Wu Gui feng-He Yang Hao-Yuan zhang wen-feng zhang Department of General Surgery Mengcheng County First People's HospitalMengcheng 233500Anhui ProvinceChina Department of Medical Imaging Mengcheng County First People's HospitalMengcheng 233500Anhui ProvinceChina

BACKGROUND Mediastinal emphysema is a condition in which air enters the mediastinum between the connective tissue spaces within the pleura for a variety of *** can be spontaneous or secondary to chest trauma,esophageal perforation,medi-cally induced factors,*** common symptoms are chest pain,tightness in the chest,and respiratory *** mediastinal emphysema patients have mild symptoms,but severe mediastinal emphysema can cause respiratory and circulatory failure,resulting in serious *** SUMMARY A 75-year-old man,living alone,presented with sudden onset of severe epigastric pain with chest tightness after drinking *** to the remoteness of his residence and lack of neighbors,the patient was found by his nephew and brought to the hospital the next morning after the disease *** tomography(CT)showed free gas in the abdominal cavity,mediastinal emph-ysema,and subcutaneous *** gastrointestinal angiography showed that the esophageal mucosa was intact and the gastric antrum was ***,we chose to perform open gastric perforation repair on the patient under thoracic epidural anesthesia combined with intravenous *** operative incision of the muscle layer of the patient's abdominal wall was made,and a large amount of subperitoneal gas was *** a continued incision of the peritoneum revealed the presence of a perforation of approx-imately 0.5 cm in the gastric antrum,which we repaired after pathological ***,the patient received high-flow oxygen and cough *** CT was performed on the first and sixth postoperative days,and the mediastinal and subcutaneous gas was gradually *** After gastric perforation,a large amount of free gas in the abdominal cavity can reach the mediastinum through the loose connective tissue at the esophageal hiatus of the diaphragm,and upper gastrointestinal angiography can clarify the site of *** pat

关键词： Gastric ulcer Perforated Mediastinal emphysema Case report

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Study on buffering performance of thin-walled metal tube with different angles

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Defence Technology（防务技术） 2018年第6期14卷 702-708页

作者： Qun Liu wen-tao Wang wen-feng zhang Beijing Institute of Space Mechanics and Electricity BeijingChina

High frequency shock load is often generated during pyrotechnic device working, which is detrimental to spacecraft structures and electric devices. Therefore, it is valuable to reduce the shock load in pyrotechnic device design. Actually, there are several ways to decrease pyroshock loads, such as reduction of powder,installation of buffering structure, insulation of damageable devices, and so on. Considered assuring the function of pyrotechnic device and minimum of structure modification, shock absorbing structure is more propitious to be introduced in pyrotechnic device. In this paper, based on the method of thinwalled metal tube diameter-expanding, a thin-walled tube shock buffering structure was designed on a separate bolt. Built on the simplified structure of a separate bolt, the model of cone piston impacting thin-walled tube absorber was established, and the thin-walled tube shock absorbing characteristics and the relation between cone angles and absorber performance were analyzed. The results showed that the change of buffering force of thin-walled tube could be divided into four phases, and each phase was correspondent to the cone piston structure. In addition, as the cone angle increases, the max shock acceleration changes in the style of decrease-increase-decrease-increase, which is the result of coupled effects of cone piston max enter depth, buffering force and energy loss. In short, these results could establish the relationships between thin-walled tube absorbing performance and its structure, which is of significance to develop low-shock pyrotechnic device.

关键词： Pyroshock Shock absorbing Thin-walled metal tube

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QFS-domains and Quasicontinuous Domains

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Acta Mathematica Sinica,English Series 2015年第2期31卷 295-304页

作者： wen feng zhang Xiao Quan XU Department of Mathematics Sichuan University School of Mathematics and Computer Science Jiangxi Science & Technology Normal University Department of Mathematics Jiangxi Normal University

In this paper, we show that （1） for each QFS-domain L, L is an ωQFS-domain iff L has a countable base for the Scott topology; （2） the Scott-continuous retracts of QFS-domains are QFS- domains; （3） for a quasicontinuous domain L, L is Lawson compact iff L is a finitely generated upper set and for any x1, x2 ∈ L and finite G1, G2 C L with G1 〈〈 x1, G2 〈〈 x2, there is a finite subset F C L such that ↑ x1 x2 G2; （4） L is a QFS-d0main iff L is a quasicontinuous domain and given any finitely many pairs {（Fi, xi）： Fi is finite, xi ∈ L with Fi 〈〈 xi, 1 ≤i ≤n}, there is a quasi-finitely separating function 5 on L such that Fi 〈〈 δ（xi）〈〈 xi.

关键词： QFS-domain quasicontinuous domain Scott topology Lawson compact

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Bubble-templated Construction of Three-dimensional Ceramic Network for Enhanced Thermal Conductivity of Silicone Rubber Composites

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Chinese Journal of Polymer Science 2021年第7期39卷 789-795页

作者： Shou-Jun Li Jing-Chao Li Pei-ZhiJi wen-feng zhang Yong-Lai Lu Li-Qun zhang State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China Beijing Key Laboratory of Wood Science and Engineering&MOE Key Laboratory of Wooden Material Science and Application Beijing Forestry UniversityBeijing W0083China Key Laboratory of Carbon Fiber and Functional Polymers Ministry of EducationBeijing University of Chemical TechnologyBeijing 100029China Engineering Research Center of Elastomer Materials Energy Conservation and Resources Ministry of EducationBeijing University of Chemical TechnologyBeijing 100029China

With the continuous development of the electronics industry,the energy density of modern electronic devices increases constantly,thus releasing a lot of heat during *** electronic devices take higher and higher request to the thermal interface *** high thermal conductivity needs to establish an interconnecting thermal conductivity network in the *** this purpose,the suspension of Al203 and curdlan was first foamed to construct a bubble-templated continuous ceramic *** to the rapid gelation property of curdlan,we can easily remove moisture by hot air ***,the high thermally conductive composites are prepared by vacuum impregnation of silicone *** result showed that composites prepared by our method have higher thermal conductivity than the samples obtained by traditional *** thermal conductivity of the prepared composite material reached 1.253 W·m^(-1)·K·^-(1)when the alumina content was 69.6 wt%.This facile method is expected to be applied to the preparation of high-performance thermal interface materials.

关键词： Thermally conductive network Alumina Curdlan Thermal conductivity

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A multi-stream network for retrosynthesis prediction

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Frontiers of Computer Science 2024年第2期18卷 231-233页

作者： Qiang zhang Juan LIU wen zhang feng YANG Zhihui YANG Xiaolei zhang Institute of Artificial Intelligence School of Computer ScienceWuhan UniversityWuhan 430072China College of Informatics Huazhong Agricultural UniversityWuhan 430072China

1 Introduction Retrosynthesis aims to predict a set of reactants for producing given molecules[1],which plays a significant part in the biochemistry field,such as molecular pathway design and drug *** existing methods perform better in solving this problem,most of these methods[2,3]only describe the molecules from one kind of perspective,such as they use Simplified Molecular Input Line Entry System(SMILES)strings[4]to represent the atomic components and the relationship between atoms of molecules or leverage Extended Connectivity Fingerprints(ECFPs)represent the information of the molecular sub-structure composition via binary vectors[5].

关键词： synthesis reactant hough

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Highly reversible Zn anode enabled by anticatalytic carbon layer with suppressed hydrogen evolution

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Rare Metals 2024年第7期43卷 3044-3054页

作者： wen-Duo zhang Chuang Sun Yu-Xuan Zhu feng Gao Chao Lai School of Chemistry and Materials Science Jiangsu Normal UniversityXuzhou221116China

Aqueous zinc-ion batteries(AZIBs)have emerged as a promising high-efficiency energy storage system due to the high energy density,low-cost and environmental ***,the practical application of AZIBs is severely restricted by the challenges faced by the Zn anode,which include uncontrollable dendrite growth,corrosion and hydrogen evolution ***,a simple and convenient physical vapor deposition(PVD)method is reported for fabricating uniform graphite as a protection layer on the surface of Zn *** high conductivity graphite layer on Zn anode(denoted as Zn@C)not only benefits the uniform distribution of the electric field,but also provides numerous Zn nucleation sites to regulate and navigate Zn-ion stripping/plating ***,the graphite layer with a poor catalytic activity endows the Zn@C anode with a highly suppressed hydrogen ***,a hydrogen and dendrite free anode is achieved with artificial anticatalytic carbon layer on Zn anode,exhibiting a high reversibility and excellent cycling stability over 2600 h at the current density of 5 mA·cm^(-2)with a capacity of 2.5 mAh·cm^(-2)and longtime cycling stability for assembled full *** work strategically designs the properties of the artificial interface layer to effectively address various challenges simultaneously,which presents insights for the future development of high-performance rechargeable AZIBs.

关键词： Zn metal anode Artificial anticatalytic layer Hydrogen suppression Dendrite free

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Encoding and display technologies for combinatorial libraries in drug discovery:The coming of age from biology to therapy

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3362-3384页

作者： Yu Fan Ruibing feng Xinya zhang Zhen-Liang Wang feng Xiong Shuihua zhang zhang-feng Zhong Hua Yu Qing-wen zhang zhang zhang Yitao Wang Guodong Li Macao Centre for Research and Development in Chinese Medicine State Key Laboratory of Quality Research in Chinese MedicineInstitute of Chinese Medical SciencesUniversity of MacaoMacao SAR 999078China State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoMacao SAR 999078China International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development Ministry of Education(MoE)of People’s Republic of ChinaCollege of PharmacyJinan UniversityGuangzhou 510632China Zhuhai UM Science and Technology Research Institute Zhuhai 519031China Department of Pharmacy Guangzhou Red Cross HospitalFaculty of Medical ScienceJinan UniversityGuangzhou 510632China Geriatric Medicine First People’s Hospital of XinXiang and the Fifth Affiliated Hospital of Xinxiang Medical CollegeXinxiang 453100China Shenzhen Innovation Center for Small Molecule Drug Discovery Co. Ltd.Shenzhen 518000China

Drug discovery is a sophisticated process that incorporates scientific innovations and cuttingedge *** to traditional bioactivity-based screening methods,encoding and display technologies for combinatorial libraries have recently advanced from proof-of-principle experiments to promising tools for pharmaceutical hit discovery due to their high screening efficiency,throughput,and resource *** review systematically summarizes the development history,typology,and prospective applications of encoding and displayed technologies,including phage display,ribosomal display,mRNA display,yeast cell display,one-bead one-compound,DNA-encoded,peptide nucleic acidencoded,and new peptide-encoded technologies,and examples of preclinical and clinical *** discuss the progress of novel targeted therapeutic agents,covering a spectrum from small-molecule inhibitors and nonpeptidic macrocycles to linear,monocyclic,and bicyclic peptides,in addition to *** also address the pending challenges and future prospects of drug discovery,including the size of screening libraries,advantages and disadvantages of the technology,clinical translational potential,and market *** review is intended to establish a comprehensive high-throughput drug discovery strategy for scientific researchers and clinical drug developers.

关键词： Drug screening Phage display DNA-encoded chemical libraries Peptide-encoded chemical libraries Clinical drugs

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Catalytic oxidation of pentanethiol on basic nitrogen doped carbon hollow spheres derived from waste tires

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Petroleum Science 2022年第4期19卷 1888-1896页

作者： Jing Luo wen-feng zhang Yan-Chen Wei Ji-Xing Liu Chao Wang Yi-Ru Zou Hai-Tao Ju Li-Ping Mu Yan-Hong Chao Hong-Bing Ji wen-Shuai Zhu School of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang212013JiangsuChina School of Materials Science and Engineering Jiangsu UniversityZhenjiang212013JiangsuChina School of the Environment and Safety Engineering Jiangsu UniversityZhenjiang212013JiangsuChina College of Chemical Engineering and Environment State Key Laboratory of Heavy Oil ProcessingChina University of Petroleum-BeijingChangping102249BeijingChina School of Chemistry Sun Yat-Sen UniversityGuangzhou510275GuangdongChina

A series of basic nitrogen doped carbon hollow spheres(p-N-C) catalysts derived from waste tires were prepared by a green, facile and environmental “leavening” strategy for the catalytic oxidation of pentanethiol. Compared to pristine carbon, the p-N-C has a higher surface curvature conducive to the enrichment of substrates, leading to an excellent catalytic performance. This increased surface curvature of p-N-C was fabricated on the synergistic effect of two foaming agents((NH4)2 C2 O4 and NaHCO3), and the released gas also endows the spherical shell of p-N-C with a hierarchical porous structure, promoting the accessibility of active sites with pentanethiol. Pyridine-like and pyrrolic-like nitrogen atoms were investigated as reactive sites on the p-N-C to accelerate the electron transfer from sulfur to active surface oxygen and enhance the adsorption/oxidation process. As a result, the optimal p-N-C catalyst exhibits superior adsorption and oxidation performance(99.9%) of pentanethiol, outperforming the “unleavened”catalyst(20.8%). This work offers a new avenue for the fabrication of highly efficient materials for the desulfurization of fuel.

关键词： Carbon hollow spheres Nitrogen-doping Waste tires Leavening strategy Pentanethiol

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Antimicrobial resistance characteristics and phylogenetic relationships of pleuromutilin-resistant Enterococcus isolates from different environmental samples along a laying hen production chain

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Journal of Environmental Sciences 2024年第3期137卷 195-205页

作者： Cong Lin Yuxuan feng Xianjun Xie Haoyu zhang Jie Wu Yixiao Zhu Jing Yu Jingyi feng wen Su Shanming Lai Anyun zhang Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province Key Laboratory of Bio-Resource and Eco-Environment of Ministry of EducationCollege of Life SciencesSichuan UniversityChengdu 610065China

Antimicrobial resistance in the laying hen production industry has become a serious public health *** antimicrobial resistance and phylogenetic relationships of the common conditional pathogen Enterococcus along the laying hen production chain have not been systematically clarified.105 Enterococcus isolates were obtained from 115 environmental samples (air,dust,feces,fies,sewage,and soil) collected along the laying hen production chain (breeding chicken,chick,young chicken,and commercial laying hen).These Enterococcus isolates exhibited resistance to some clinically relevant antibiotics,such as tetracycline (92.4%),streptomycin (92.4%),and erythromycin (91.4%),and all strains had multidrug resistance *** genome sequencing characterized 29 acquired antibiotic resistance genes (ARGs) that conferred resistance to 11 classes of antibiotics in 51pleuromutilin-resistant Enterococcus isolates,and lsa(E),which mediates resistance to pleuromutilins,always co-occurred with lnu(B).Alignments with the Mobile Genetic Elements database identified four transposons (Tn554,Tn558,Tn6261,and Tn6674) with several ARGs(erm(A),ant(9)-la,fex(A),and optrA) that mediated resistance to many clinically important ***,we identified two new transposons that carried ARGs in the Tn554 family designated as Tn7508 and Tn7492.A complementary approach based on conventional multi-locus sequence typing and whole genome single nucleotide polymorphism analysis showed that phylogenetically related pleuromutilin-resistant Enterococcus isolates were widely distributed in various environments on different production *** results indicate that environmental contamination by antimicrobial-resistant Enterococcus requires greater attention,and they highlight the risk of pleuromutilin-resistant Enterococcus and ARGs disseminating along the laying hen production chain,thereby warranting effective disinfection.

关键词： Antimicrobial resistance Enterococcus Laying hen production chain Pleuromutilin

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Sensing-Assisted Accurate and Fast Beam Management for Cellular-Connected mmWave UAV Network

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China Communications 2024年第6期21卷 271-289页

作者： Cui Yanpeng zhang Qixun feng Zhiyong Qin wen Zhou Ying Wei Zhiqing zhang Ping School of Information and Communication Engineering Beijing University of Posts and TelecommunicationsBeijing 100876China School of Computer Science Northwestern Polytechnical UniversityXi’an 710072China

Beam management,including initial access(IA)and beam tracking,is essential to the millimeter-wave Unmanned Aerial Vehicle(UAV)***,the conventional communicationonly and feedback-based schemes suffer a high delay and low accuracy of beam alignment,since they only enable the receiver to passively“hear”the information of the transmitter from the radio *** paper presents a novel sensing-assisted beam management approach,the first solution that fully utilizes the information from the visual domain to improve communication *** employ both integrated sensing and communication and computer vision techniques and design an extended Kalman filtering method for beam tracking and ***,we also propose a novel dual identity association solution to distinguish multiple UAVs in dynamic ***-world experiments and numerical results show that the proposed solution outperforms the conventional methods in IA delay,association accuracy,tracking error,and communication performance.

关键词： beam management integrated sensing and communication UAV communication

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