检索结果-南通市图书馆

Direct observation of spreading precursor liquids in a corner

在线全文

学校读者我要写书评

暂无评论

National Science Review 2023年第7期10卷 196-202页

作者： Weining Miao Shihao tian Quanzi Yuan Ye tian Lei Jiang Key Laboratory of Bioinspired Smart Interfacial Science Technical Institute of Physics and Chemistry Chinese Academy of Sciences School of Future Technology University of Chinese Academy of Sciences State Key Laboratory of Nonlinear Mechanics Institute of Mechanics Chinese Academy of Sciences School of Engineering Science University of Chinese Academy of Sciences

Precursor liquid is a nanoscale liquid creeping ahead of the macroscopic edge of spreading liquids,whose behaviors tightly correlate with the three-phase reaction efficiency and patterning ***,the important spatial-temporal characteristic of the precursor liquid still remains obscure because its real-time spreading process has not been directly ***,we report that the spreading ionic liquid precursors in a silicon corner can be directly captured on video using in situ scanning electron *** situ spreading videos show that the precursor liquid spreads linearly over time(ΔL～ΔT) rather than obeying the classic Lucas-Washburn law(l～t1/2) and possesses a characteristic width of ～250-310 *** analyses and molecular dynamics simulations demonstrate that the unique behaviors of precursor liquids originate from the competing effect of van der Waals force and surface *** findings provide avenues for directly observing liquid/solid interfacial phenomena on a microscopic level.

关键词： precursor liquid spreading spatial–temporal characteristic direct observation corner ionic liquids

Optimal linear estimators for systems with random measurement delays

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

控制理论与应用（英文版） 2011年第1期9卷 76-82页

作者： Sun, Shuli tian, tian School of Electronic Engineering Heilongjiang University Harbin Heilongjiang 150080 China

This paper is concerned with the optimal linear estimation problem for linear discrete-time stochastic systems with random measurement delays. A new model that describes the random delays is constructed where possible the largest delay is bounded. Based on this new model, the optimal linear estimators including filter, predictor and smoother are developed via an innovation analysis approach. The estimators are recursively computed in terms of the solutions of a Riccati difference equation and a Lyapunov difference equation. The steady-state estimators are also investigated. A sufficient condition for the convergence of the optimal linear estimators is given. A simulation example shows the effectiveness of the proposed algorithms.

关键词： Optimal linear estimation Random measurement delays Innovation analysis approach Riccati difference equation Lyapunov difference equation

Warming magnitude of Indonesian Throughflow during the penultimate deglaciation (Termination Ⅱ) and its relationship with climate change in high-latitude regions

在线全文

学校读者我要写书评

暂无评论

Chinese Science Bulletin 2010年第32期55卷 3709-3717页

作者： tian CuiCui tian Jun State Key Laboratory of Marine Geology Tongji University Shanghai 200092 China

The tropical oceans are important source areas for global heat and water vapor transport,and changes in tropical sea surface temperature (SST) will have important impacts on high-latitude and global climate change. It is crucial to establish the precise phase relationship between tropical and high-latitude climate variability to gain insight into the mechanisms of global climate change. Here,we present multi-proxy records across the penultimate deglaciation (Termination Ⅱ) from sediment Core SO18459,which is located in the outflow area of the Indonesian Throughflow (ITF) of the Timor Sea. These proxy records include planktonic and benthic foraminifera δ 18O,planktonic foraminifera G. ruber Mg/Ca-derived SST,and δ18Ow of sea surface water. The Mg/Ca-SST records indicate a warming of 4.1°C in the Timor Sea over Termination Ⅱ,which is in phase with decrease in planktonic and benthic δ18O. Our results suggest that at millennial timescales,climate change of the tropical oceans is synchronous with high-latitude ice volume changes. Furthermore,warming of the Timor Sea is almost simultaneous with warming of the Antarctic,suggesting a rapid heat transfer from the tropics to the Antarctic via the atmosphere and/or ocean circulations. The G. ruber δ18O and SST records of Core SO18459 show a marked YD-like event during Termination Ⅱ,which is probably caused by decrease in Australian rainfall or strengthening of the Western Pacific Warm Pool. However,a similar YD-like event is not observed in East Asian rainfall records. This discrepancy indicates that different tropical climate systems may have different responses to the same forcing,such as El Nio Southern Oscillation. A similar YD-like event is observed in the global benthic foraminiferal δ18O records during Termination Ⅱ,implying teleconnection of millennial scale climate change between the tropical regions and high latitudes.

关键词：印度尼西亚贯穿流高纬度地区气候变暖冰消期倒数全球气候变化热带海洋底栖有孔虫

L^p Solutions of Backward Stochastic Volterra Integral Equations

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2012年第9期28卷 1875-1882页

作者： tian Xiao WANG School of Mathematics Shandong University

This paper is devoted to the unique solvability of backward stochastic Volterra integral equations （BSVIEs, for short）, in terms of both M-solution and the adapted solutions. We prove the existence and uniqueness of M-solutions of BSVIEs in Lp （1 〈 p 〈 2）, which extends the existing results on M-solutions. The unique solvability of adapted solutions of BSVIEs in Lp （p 〉 1） is also considered, which also generalizes the results in the existing literature.

关键词： Backward stochastic Volterra integral equations M-solutions Lp solutions adapted solutions

B-cell immune checkpoint TIM-1: a potential target for tumour immunotherapy

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2023年第11期8卷 5149-5150页

作者： Xinyu tian Xiangyun Zheng Dong tian Department of Thoracic Surgery West China HospitalSichuan University37 Guoxue AlleyChengdu610041China Lung Transplant Research Laboratory Institute of Thoracic OncologyWest China HospitalSichuan University37 Guoxue AlleyChengdu610041China

Recently,Lloyd Bod et *** a study in Nature that identified the B-cell immune checkpoint T cell immunoglobulin and mucin domain 1(TIM-1)and mechanistically elucidated that targeting TIM-1 enhances the responses to type I interferon(IFN-I),promotes B cells antigen presentation and activation,subsequently enhances anti-tumour responses of CD4^(+) and CD8^(+)T cells and inhibits tumour *** study provides important implications for anti-tumour therapy.

关键词： tumour interferon

Silicone Elastomer with High Elongation at Break Used in Digital Light Processing 3D Printing

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2023年第11期41卷 1786-1795,I0010页

作者： tian-Xin Yu Ya-Yuan Liu Fu-Yue tian Nan-Ying Ning Bing Yu Ming tian State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical TechnologyBeijing 100029China Key Laboratory of Carbon Fiber and Functional Polymers Ministry of EducationBeijing University of Chemical TechnologyBeijing 100029China

3D printing silicone elastomer has demonstrated great potential in diverse areas such as medical devices,flexible electronics and soft *** is of great value to investigate how to improve the mechanical properties,including tensile strength and elongation at break of printed *** this work,a light curing system that can be applied in silicone elastomer 3D printing is explored,which is composed of vinyl terminated polysiloxane as the macromer and thiol containing polysiloxane as the crosslinking agent,and a chain extension reaction is also introduced into this light curing system via the addition of the chain extender dithiol molecules,and a light curing system accompanied with chain extension is designed and realized based on the thiol-ene click reaction *** reinforced with silica fillers,the obtained light curing system can endow the light curing silicone elastomer with better mechanical properties under the condition of a lower viscosity of the precursor,the tensile strength and elongation at break can reach 525.5 k Pa and 601%,*** light curing system provides a feasible method to solve the contradiction between the viscosity of the precursor and the mechanical properties of the light curing elastomer in the digital light processing(DLP)3D printing field.

关键词： Silicone elastomer Thiol-ene click chemistry Light curing 3D-printing Chain extender

Radiokrypton dating coming of age

在线全文

学校读者我要写书评

暂无评论

National Science Review 2016年第2期3卷 172-173页

作者： Zheng-tian Lu Hefei National Laboratory for Physical Sciences at the Microscale Synergetic Innovation Center of Quantum Information & Quantum PhysicsUniversity of Science and Technology of China

The dream of radiokrypton dating began in 1969 when Heinz Hugo Loosli and Hans Oeschger of the University of Bern first detected the decay of;Rr（half-life=230 000 yr）in krypton gas extracted from air[1].This isotope is produced in the upper atmosphere by cosmic-ray-induced spallation and neutron-activation of stable *** to its long residence time（;0;yr）in the atmosphere,;Rr is uniformly

关键词： Radiokrypton dating coming of age ATA

Metallurgical challenges in microelectronic 3D IC packaging technology for future consumer electronic products

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2013年第7期56卷 1740-1748页

作者： K. N. TU tian tian Department of Mechanical and Biomedical Engineering City University of Hong Kong Department of Materials Science and Engineering University of California at Los Angeles

Metallurgical challenges in controlling the microstructural stability of Cu and solder microbumps in 3D IC packaging technol-ogy are discussed. Using uni-directional oriented nanotwinned Cu, the controlled growth of oriented Cu6Sn5 on the nanotwinned Cu and its transformation to Cu3Sn without Kirkendall voids have been achieved. In order to join a stack of Si chips into a 3D device, multiple reflows of solder microbumps may be required; we consider localized heating to do so by the use of self-sustained explosive reaction in multi-layered Al/Ni thin films of nano thickness. It avoids re-melting of those solder joints which have been formed already in the 3D stacking structure.

关键词： 3D IC packaging microbump localized heating

CCL9/CCR1 axis-driven chemotactic nanovesicles for attenuating metastasis of SMAD4-deficient colorectal cancer by trapping TGF-β

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第8期14卷 3711-3729页

作者： Boning Niu tianyi tian Lu Wang Yinmei tian tian tian Yuanyuan Guo Hu Zhou Zhiping Zhang Tongji School of Pharmacy Huazhong University of Science and TechnologyWuhan 430030China Department of Oncology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Pharmacy Liyuan HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China School of Pharmaceutical Sciences Fujian Provincial Key Laboratory of Innovative Drug Target ResearchHigh Throughput Drug Screening PlatformXiamen UniversityXiamen 361102China National Engineering Research Center for Nanomedicine Huazhong University of Science and TechnologyWuhan 430030China Hubei Engineering Research Centre for Novel Drug Delivery System Huazhong University of Science and TechnologyWuhan 430030China

SMAD4 deficiency in colorectal cancer(CRC)is highly correlated with liver metastasis and high mortality,yet there are few effective precision therapies ***,we show that CCR1^(+)-granulocytic myeloid-derived suppressor cells(G-MDSCs)are highly infiltrated in SMAD4-deficient CRC via CCL15/CCR1 and CCL9/CCR1 axis in clinical specimens and mouse models,*** excessive TGF-β,secreted by tumor-infiltrated CCR1^(+)-G-MDSCs,suppresses the immune response of cytotoxic T lymphocytes(CTLs),thus facilitating ***,we develop engineered nanovesicles displaying CCR1 and TGFBR2 molecules(C/T-NVs)to chemotactically target the tumor driven by CCL9/CCR1 axis and trap TGF-βthrough TGF-β-TGFBR2 specific *** C/T-NVs counteract CCR1^(+)-G-MDSC infiltration through competitive responding CCL9/CCR1 axis.C/T-NVs-induced intratumoral TGF-βexhaustion alleviates the TGF-β-suppressed immune response of ***,C/T-NVs attenuate liver metastasis of SMAD4-deficient *** further exploration,high expression of programmed cell death ligand-1(PD-L1)is observed in clinical specimens of SMAD4-deficient *** C/T-NVs with anti-PD-L1 antibody(aPD-L1)induces tertiary lymphoid structure formation with sustained activation of CTLs,CXCL13^(+)-CD4^(+)T,CXCR5^(+)-CD20^(+)B cells,and enhanced secretion of cytotoxic cytokine interleukin-21 and IFN-γaround tumors,thus eradicating metastatic *** strategy elicits pleiotropic antimetastatic immunity,paving the way for nanovesicle-mediated precision immunotherapy in SMAD4-deficient CRC.

关键词： SMAD4-deficient CRC Metastasis G-MDSCs TGF-β CCR1 TGFBR2