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Combined phacoemulsification and goniosynechialysis with or without endoscopic cyclophotocoagulation in the treatment of PACG with cataract

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International Journal of Ophthalmology(English edition) 2020年第9期13卷 1385-1390页

作者： wan-shu zhou Wen-Xiang Lin Yun-Yun Geng Tao wang Beijing Tongren Eye Center Beijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Tongren HospitalCapital Medical UniversityBeijing 100730China

AIM:To investigate the efficacy and safety of combined phacoemulsification and goniosynechialysis with or without endoscopic cyclophotocoagulation(PGE group and PG group)for the treatment of patients with coexisting primary angle-closure glaucoma(PACG)and ***:The clinical data of patients with PACG and cataract were retrospectively *** was a total of 88 eyes in the study and were divided into two groups,42 eyes in PGE group and 46 eyes in PG *** success cumulative survival,preoperative and postoperative intraocular pressure(IOP),number of IOPlowering medications,best corrected visual acuity(BCVA)in the two groups were observed for more than 12 mo and compared within each group and between two ***:The mean IOP in PGE group declined from24.9 mm Hg preoperatively to 14.1 mm Hg at the first month after operation(P<0.001)and at the last visit 16.2 mm Hg(P<0.001).Meanwhile PG group also showed significant decrease,from 24.1 mm Hg preoperatively to 13.0 mm Hg at Imo after operation(P<0.001)and 15.3 mm Hg at the last visit(P=0.004).The mean medications reliance reduced in both groups,in PGE group was reduced from 1.62 preoperatively to 0.13 at the last visit(P<0.001),in PG group from 0.87 to 0.10(P<0.001).At the last visit,BCVA increased from 0.21 to 0.60 in PGE group(P<0.001)and from 0.24 to 0.67 in PG group(P<0.001).The success rate of PGE group at 1 mo was95.2%,then decreased to 70.7%at the last visit,whereas in PG group,the success rate at 1 mo was 100%,at the last visit was 73.4%.CONCLUSION:PGE shows promise for PACG patients with cataracts to reduce IOP,lighten the medication burden and improve visual acuity,and PG still has its value in specific patients.

关键词： endoscopic cyclophotocoagulation primary angle-closure glaucoma cataract combined glaucoma and cataract surgery laser surgery

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基于3S技术的辽河河口湿地生态环境需水量研究

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节水灌溉 2017年第7期 84-87,93页

作者：张琬抒周林飞成遣沈阳农业大学水利学院沈阳110866

利用3S技术对辽河河口湿地覆被信息进行提取,为生态环境需水量计算提供数据基础。根据研究区的实际情况和生态系统特征确定生态环境需水量的计算类型和计算方法,经计算结果表明:适宜生态环境需水量为2.74亿m3/a;多年平均降雨下、75%频... 详细信息

利用3S技术对辽河河口湿地覆被信息进行提取,为生态环境需水量计算提供数据基础。根据研究区的实际情况和生态系统特征确定生态环境需水量的计算类型和计算方法,经计算结果表明:适宜生态环境需水量为2.74亿m3/a;多年平均降雨下、75%频率下和95%频率下对应的最小生态环境需水量分别为0.78、0.94和1.10亿m3/a。为有利于水资源的优化配置,给出了它们的生态环境逐月需水过程。在缺水的情况下,最小生态需水量计算是非常重要的。

关键词：辽河河口湿地适宜生态环境需水量最小生态环境需水量

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重度妊高征并发腹水48例临床分析

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实用妇产科杂志 2004年第5期20卷 277-278页

作者：罗丹王红静周淑罗艳王世阆四川大学华西第二医院四川成都610041 蒲江人民医院四川蒲江611600

目的 :分析重度妊娠高血压综合征 (简称妊高征 )并发腹水的临床特点和防治方法。方法 :将我院 1996年 1月～ 2 0 0 2年 12月间 2 0 4例重度妊高征分为并发腹水组 (A组 ,4 8例 )和未并发腹水组 (B组 ,15 6例 ) ,比较其临床特点。结果 :A... 详细信息

目的 :分析重度妊娠高血压综合征 (简称妊高征 )并发腹水的临床特点和防治方法。方法 :将我院 1996年 1月～ 2 0 0 2年 12月间 2 0 4例重度妊高征分为并发腹水组 (A组 ,4 8例 )和未并发腹水组 (B组 ,15 6例 ) ,比较其临床特点。结果 :A、B两组间比较 ,终止妊娠的时间、肝功能检查总蛋白、白蛋白、白 /球比值、乳酸脱氢酶、血肌酐、2 4小时尿蛋白定量、宫内死胎发生率、新生儿早产发生率、孕产妇并发症的发生率差异有显著性 (P <0 .0 5 )。结论 :重度妊娠高血压综合征并发腹水病情极为严重 ,应及时终止妊娠 ,分娩后腹水可消退 ;早期、系统、定期的产前检查可及时发现、预防重度妊高征及并发症的发生。

关键词：妊娠高血压综合征并发症腹水预后

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Host-Induced Gene Silencing of Effector AGLIP1 Enhanced Resistance of Rice to Rhizoctonia solani AG1-IA

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Rice science 2024年第4期31卷 463-474,I0031-I0034页

作者： ZHAO Mei LIU Xiaoxue wan Jun zhou Erxun shu Canwei Pesticide State Key Laboratory of Green Pesticide Guangdong Province Key Laboratory of Microbial Signals and Disease ControlCollege of Plant ProtectionSouth China Agricultural UniversityGuangzhou 510642China College of Life Science and Engineering Henan University of Urban ConstructionPingdingshan 467036China

Rice sheath blight, caused by Rhizoctonia solani AG1-IA, is a major disease in rice-growing areas worldwide. Effectors of phytopathogenic fungi play important roles during the infection process of fungal pathogens onto their host plants. However, the molecular mechanisms by which R. solani effectors regulate rice immunity are not well understood. Through prediction, 78 candidate effector molecules were identified. Using the tobacco rattle virus-host induced gene silencing(TRV-HIGS) system, 45 RNAi constructs of effector genes were infiltrated into Nicotiana benthamiana leaves. The results revealed that eight of these constructs resulted in a significant reduction in necrosis caused by infection with the AG1-IA strain GD-118. Additionally, stable rice transformants carrying the double-stranded RNA construct for one of the effector genes, AGLIP1, were generated to further verify the function of this gene. The suppression of the AGLIP1 gene increased the resistance of both N. benthamiana and rice against GD-118, and also affected the growth rate of GD-118, indicating that AGLIP1 is a key pathogenic factor. Small RNA sequencing showed that the HIGS vectors were processed into si RNAs within the plants and then translocated to the fungi, leading to the silencing of the target genes. As a result, AGLIP1 might be an excellent candidate for HIGS, thereby enhancing crop resistance against the pathogen and contributing to the control of R. solani infection.

关键词： Rhizoctonia solani host-induced gene silencing lipase tobacco rattle virus

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Use of Helical Strakes for FIV Suppression of Two Inclined Flexible Cylinders in A Side-by-Side Arrangement

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China Ocean Engineering 2018年第3期32卷 331-340页

作者： XU wan-hai ZHANG shu-hai zhou Li-dan GAO Xi-feng State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin UniversityTianjin 300072China Collaborative Innovation Centre for Advanced Ship and Deep-Sea Exploration Shanghai 200240China

The experimental studies on flow-induced vibrations(FIV) reduction of two side-by-side flexible cylinders inclined at 45° by using the helical strakes were carried out in a towing tank. The main aim of the experiment is to check whether the helical strakes with a pitch of 17.5 D and a height of 0.25 D, which is considered as the most effective vibration suppression device for the isolated cylinder undergoing vortex-shedding, still perform very well to reduce FIV of two inclined flexible cylinders in a side-by-side arrangement. The vibration of two identical inclined cylinders with a mass ratio of 1.90 and an aspect ratio of 350 was tested in the experiment. The center-to-center distance between the two cylinders was 3.0 D. The uniform flow was simulated by towing the cylinder models along the *** towing velocity varied from 0.05 to 1.0 m/s with an interval of 0.05 m/s. The maximum Reynolds number can be up to 1.6×104. Three cases were experimentally studied in this paper, including two side-by-side inclined smooth cylinders, only one smooth cylinder fitted with helical strakes in the two side-by-side inclined cylinders system and both two cylinders attached with helical strakes. The variations of displacement amplitude, dominant frequency, FIV suppression efficiency and dominant mode for the two side-by-side inclined cylinders with reduced velocity were shown and discussed.

关键词： helical strakes FIV suppression inclined cylinder side-by-side towing tank experiment

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Enhanced elastic beam model with BADS integrated for settlement assessment of immersed tunnels

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Underground Space 2023年第5期12卷 79-88页

作者： Cong Tang shu-Yu He Zheng Guan wan-Huan zhou Zhen-Yu Yin State Key Laboratory of Internet of Things for Smart City and Department of Civil and Environmental Engineering University of MacaoTaipaMacao 999078China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong Kong 999077China

Excessive settlement may induce structural damage and water leakage in immersed tunnels,seriously threatening the tunnels’***,making accurate assessment of the settlement in immersed tunnels is difficult due to the incomplete knowledge of the geotechnical parameters and the inadequacy of the model *** paper proposes an effective method to accurately assess the settlement in immersed *** enhanced beam on elastic foundation model(E-BEFM)is developed for the settlement assessment,with the Bayesian adaptive direct search algorithm adopted to estimate unknown model parameters based on previous *** proposed method is applied to a field case of the Hong Kong–Zhuhai–Macao immersed *** original BEFM is used for comparison to highlight the better assessment performance of E-BEFM,particularly for joints’differential *** show that the proposed method can provide accurate predictions of the total settlement,angular distortion(a representation of tubes’relatively differential settlement),and joints’differential settlement,which consequently supports the associated maintenance decision-making and potential risk prevention for immersed tunnels in service.

关键词： Immersed tunnel Settlement Beam on elastic foundation model Bayesian adaptive direct search Hong Kong-Zhuhai-Macao tunnel

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SARS-CoV-2 Omicron variant:recent progress and future perspectives

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Signal Transduction and Targeted Therapy 2022年第5期7卷 1586-1596页

作者： Yao Fan Xiang Li Lei Zhang shu wan Long Zhang Fangfang zhou School of Medicine Zhejiang University City College310015 HangzhouZhejiangChina Institutes of Biology and Medical Science Soochow University215123 SuzhouPRChina The Eighth Affiliated Hospital Sun Yat-sen University518033 ShenzhenChina MOE Laboratory of Biosystems Homeostasis&Protection and Innovation Center for Cell Signaling Network Life Sciences InstituteZhejiang University310058 HangzhouChina Department of Orthopaedic Surgery The First Affiliated Hospital of Wenzhou Medical University325000 WenzhouChina Brain Center Affiliated Zhejiang HospitalZhejiang University School of Medicine310058 HangzhouChina

Since the outbreak of the coronavirus disease 2019(COVID-19)pandemic,there have been a few variants of the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),one of which is the Omicron variant(B.1.1.529).The Omicron variant is the most mutated SARS-CoV-2 variant,and its high transmissibility and immune evasion ability have raised global *** to its enhanced transmissibility,Omicron has rapidly replaced Delta as the dominant variant in several ***,recent studies have shown that the Omicron variant exhibits reduced pathogenicity due to altered cell *** addition.

关键词： acute respiratory raised

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Influence of Screw Design on Burden Descending Velocity and Particle Segregation in COREX Shaft Furnace

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Journal of Iron and Steel Research International 2016年第6期23卷 516-524页

作者： Hai-feng LI Heng zhou Tao ZHANG Yang YOU Zong-shu ZOU wan-ren XU School of Metallurgy Northeastern University Baoshan Iron and Steel Co. Ltd.

COREX shaft furnace（SF）is an industrial system that employs screw feeders;thus,the burden descending velocity and particle segregation in the SF can be directly affected by the design of screw.A three-dimensional actual size model of COREX-3000 SF was established using the discrete element *** types of burdens,including pellet,ore,flux and coke,were considered in this *** this consideration,the effect of screw design on solid flow was *** showed that,in the base case,burdens fell primarily down from the first flight of the *** burden descending velocities were nearly uniform in the peripheral direction and decreased along the radial *** addition,the normalized particle size increased in the center area and decreased in the wall *** the flight diameter of screw benefited an even flow pattern and restrained the rolling tendency of burden from the edge to center *** optimized case was also proposed,in which a uniform solid flow profile could be obtained and the evenness of descending velocity along the radius could be greatly improved.

关键词： screw COREX descending burden normalized radius Velocity segregation torque pellet

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Excellent mechanical properties and resistance to cavitation erosion for an ultra-low carbon Cr Mn N stainless steel through quenching and partitioning treatment

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International Journal of Minerals,Metallurgy and Materials 2018年第5期25卷 547-553页

作者： Ze-an zhou wan-tang Fu Zhe Zhu Bin Li Zhong-ping Shi shu-hua Sun State Key Laboratory of Metastable Materials Science and Technology Yanshan University

The retained austenite content(RAC),the mechanical properties,and the resistance to cavitation erosion(CE)of the00Cr13Mn8Mo N steel after quenching and partitioning(Q&P)processing were *** results show that the Q&P process affected the RAC,which reached the maximum value after partitioning at 400°C for 10 *** tensile strength of the steel slightly decreased with increasing partitioning temperature and ***,the elongation and product of strength and elongation first increased and then *** sample partitioned at 400°C for 10 min exhibited the optimal property:a strength-ductility of 23.8 GPa?%.The resistance to CE for the 00Cr13Mn8Mo N steel treated by the Q&P process was improved due to work hardening,spalling,and cavitation-induced martensitic transformation of the retained austenite.

关键词： CrMnN steel quenching and partitioning process retained austenite mechanical property cavitation erosion

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Strength and Microstructure of Mortar Containing Glass Powder and/or Glass Aggregate

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Journal of Wuhan University of Technology(Materials Science) 2016年第6期31卷 1302-1310页

作者：刘数华 wanG shu zhou Wei LI Lihua XIAO Henglin WEI Jianpeng TANG wan State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan University Wuhan 430072 China China Construction Ready Mixed Concrete Co. Ltd. Wuhan 430000 China School of Civil Engineering and Architecture Hubei University of Technology Wuhan 430068 China

The compressive strength of mortar containing glass powder（GP） and/or glass aggregate（GA） was tested, and its microstructure was also studied by thermogravimetric and differential thermal analysis（TG-DTA）, scanning electron microscopy（SEM）, energy dispersive spectroscopic analysis（EDX）, and X-ray diffraction（XRD） techniques. The incorporation of GA would decrease the compressive strength of the mortar in the absence of GP. Incorporating both GA and GP could change the hydration environment, promote pozzolanic reaction of GP and improve the compressive strength. GP does not lead to but can effectively control ASR（Alkali Silica Reaction）. GP and GA do not transform the type of hydrates, but have a great influence on the amounts of hydration products, and generate more calcium silicate hydrate（C-S-H gel） with lower Ca/Si ratio. GP and GA with good gradation will make the microstructure denser.

关键词： glass powder glass aggregate mortar strength microstructure

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