SARS-CoV-2 Omicron variant:recent progress and future perspectives

作     者：Yao Fan Xiang Li Lei Zhang Shu Wan Long Zhang Fangfang Zhou 

作者机构：School of MedicineZhejiang University City College310015 HangzhouZhejiangChina Institutes of Biology and Medical ScienceSoochow University215123 SuzhouPRChina The Eighth Affiliated HospitalSun Yat-sen University518033 ShenzhenChina MOE Laboratory of Biosystems Homeostasis&Protection and Innovation Center for Cell Signaling NetworkLife Sciences InstituteZhejiang University310058 HangzhouChina Department of Orthopaedic SurgeryThe First Affiliated Hospital of Wenzhou Medical University325000 WenzhouChina Brain CenterAffiliated Zhejiang HospitalZhejiang University School of Medicine310058 HangzhouChina 

出 版 物：《Signal Transduction and Targeted Therapy》 (信号转导与靶向治疗（英文）)

年 卷 期：2022年第7卷第5期

页      面：1586-1596页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学] 

基　　金：We would like to apologize to those researchers whose related work we were not able to cite in this review.This work was supported by a special program from the Ministry of Science and Technology of China(2021YFA1101000) the Chinese National Natural Science Funds(31925013 and U20A20393 to L.Z.,31871405,32125016 and 82041009 to F.Z.) Zhejiang Provincial Natural Science Foundation of China under Grant(LBY21H060001 to L.Z.) the Medical and the Medical and Health Research Project of Zhejiang Province(2020RC115 to L.Z.) Jiangsu National Science Foundation(BK20180043 and 19KJA550003 to F.Z.) the Zhejiang Natural Science Fund(LD19C070001to L.Z.) the Key Project of University Natural Science Foundation of Jiangsu Province(19KJA550003) A project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions,and the Medical and Health Research Project of Zhejiang Province(2020RC155 to L.Z.) 

主　　题：acute respiratory raised 

摘      要：Since the outbreak of the coronavirus disease 2019(COVID-19)pandemic,there have been a few variants of the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),one of which is the Omicron variant(B.1.1.529).The Omicron variant is the most mutated SARS-CoV-2 variant,and its high transmissibility and immune evasion ability have raised global *** to its enhanced transmissibility,Omicron has rapidly replaced Delta as the dominant variant in several ***,recent studies have shown that the Omicron variant exhibits reduced pathogenicity due to altered cell *** addition.